chlortetracycline is a lipid of Polyketides (PK) class. Chlortetracycline is associated with abnormalities such as Granulomatous Disease, Chronic, Infection, Ischemia, Cerebral Ischemia and Cerebral Infarction. The involved functions are known as Regulation, Binding (Molecular Function), Agent, Stimulus and Process. Chlortetracycline often locates in Protoplasm, Plasma membrane, Membrane, Cytoplasm and specific granule. The associated genes with chlortetracycline are FPR1 gene, P4HTM gene, Homologous Gene, HIST1H1C gene and Microbiome. The related lipids are Lysophosphatidylcholines, Sterols, dilauroyl lecithin, seminolipid and Total cholesterol. The related experimental models are Mouse Model.
To understand associated biological information of chlortetracycline, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
chlortetracycline is suspected in Ischemia, Cerebral Ischemia, Cerebral Infarction, Granulomatous Disease, Chronic, Infection, Antibiotic resistant infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with chlortetracycline
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Mouse Model are used in the study 'Chlortetracycline and demeclocycline inhibit calpains and protect mouse neurons against glutamate toxicity and cerebral ischemia.' (Jiang SX et al., 2005).
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Authors | Title | Published | Journal | PubMed Link |
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King JO | The continuous feeding of two antibiotics to growing rabbits. | 1967 | Br. Vet. J. | pmid:6074284 |
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Edelson HS et al. | Dissociation by piroxicam of degranulation and superoxide anion generation from decrements in chlortetracycline fluorescence of activated human neutrophils. | 1982 | Biochem. Biophys. Res. Commun. | pmid:6280690 |
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Moyed HS and Bertrand KP | Mutations in multicopy Tn10 tet plasmids that confer resistance to inhibitory effects of inducers of tet gene expression. | 1983 | J. Bacteriol. | pmid:6307969 |
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Smolen JE | The fluorescence response of chlortetracycline-loaded human neutrophils is modulated by prostaglandin E1, but not by cyclic nucleotides. | 1983 | FEBS Lett. | pmid:6313429 |
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