chlortetracycline is a lipid of Polyketides (PK) class. Chlortetracycline is associated with abnormalities such as Granulomatous Disease, Chronic, Infection, Ischemia, Cerebral Ischemia and Cerebral Infarction. The involved functions are known as Regulation, Binding (Molecular Function), Agent, Stimulus and Process. Chlortetracycline often locates in Protoplasm, Plasma membrane, Membrane, Cytoplasm and specific granule. The associated genes with chlortetracycline are FPR1 gene, P4HTM gene, Homologous Gene, HIST1H1C gene and Microbiome. The related lipids are Lysophosphatidylcholines, Sterols, dilauroyl lecithin, seminolipid and Total cholesterol. The related experimental models are Mouse Model.
To understand associated biological information of chlortetracycline, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
chlortetracycline is suspected in Ischemia, Cerebral Ischemia, Cerebral Infarction, Granulomatous Disease, Chronic, Infection, Antibiotic resistant infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with chlortetracycline
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'Chlortetracycline and demeclocycline inhibit calpains and protect mouse neurons against glutamate toxicity and cerebral ischemia.' (Jiang SX et al., 2005).
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Authors | Title | Published | Journal | PubMed Link |
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Chi Z et al. | Binding of tetracycline and chlortetracycline to the enzyme trypsin: spectroscopic and molecular modeling investigations. | 2011 | PLoS ONE | pmid:22205948 |
Nelson ML and Levy SB | The history of the tetracyclines. | 2011 | Ann. N. Y. Acad. Sci. | pmid:22191524 |
Duggar BM | Aureomycin: a product of the continuing search for new antibiotics. | 2011 | Ann. N. Y. Acad. Sci. | pmid:22191532 |
Zhang D et al. | Strong adsorption of chlorotetracycline on magnetite nanoparticles. | 2011 | J. Hazard. Mater. | pmid:21724321 |
Stone JJ et al. | Impact of chlortetracycline on sequencing batch reactor performance for swine manure treatment. | 2011 | Bioresour. Technol. | pmid:21724384 |
Guillot M et al. | In growing pigs, chlortetracycline induces a reversible green bone discoloration and a persistent increase of bone mineral density dependent of dosing regimen. | 2011 | Res. Vet. Sci. | pmid:20723952 |
Kato Y et al. | Capacitation status of activated bovine sperm cultured in media containing methyl-β-cyclodextrin affects the acrosome reaction and fertility. | 2011 | Zygote | pmid:20727245 |
Wu RB et al. | Prevalence and diversity of class 1 integrons and resistance genes in antimicrobial-resistant Escherichia coli originating from beef cattle administered subtherapeutic antimicrobials. | 2011 | J. Appl. Microbiol. | pmid:21645183 |
Volkers G et al. | Recognition of drug degradation products by target proteins: isotetracycline binding to Tet repressor. | 2011 | J. Med. Chem. | pmid:21699184 |
Bernabò N et al. | The role of actin in capacitation-related signaling: an in silico and in vitro study. | 2011 | BMC Syst Biol | pmid:21450097 |
Miah AG et al. | Intracellular signaling cascades induced by relaxin in the stimulation of capacitation and acrosome reaction in fresh and frozen-thawed bovine spermatozoa. | 2011 | Anim. Reprod. Sci. | pmid:21493019 |
Miyata M et al. | Electrochemical oxidation of tetracycline antibiotics using a Ti/IrO2 anode for wastewater treatment of animal husbandry. | 2011 | Water Sci. Technol. | pmid:21278467 |
Stone JJ et al. | Land application of tylosin and chlortetracycline swine manure: Impacts to soil nutrients and soil microbial community structure. | 2011 | J Environ Sci Health B | pmid:21877979 |
Xie X et al. | Physiological and potential genetic toxicity of chlortetracycline as an emerging pollutant in wheat (Triticum aestivum L.). | 2010 | Environ. Toxicol. Chem. | pmid:20821522 |
Wan Y et al. | [Effect of soil organic matter and cadmium (II) on adsorption and desorption of chlortetracycline in soil]. | 2010 | Huan Jing Ke Xue | pmid:21360898 |
Spisso BF et al. | Pilot survey of commercial pasteurized milk consumed in the metropolitan area of Rio de Janeiro, Brazil, for tetracyclines residues, including the 4-epimers of oxytetracycline, tetracycline and chlortetracycline. | 2010 | Food Addit Contam Part B Surveill | pmid:24779621 |
Stone JJ et al. | Tylosin and chlortetracycline effects during swine manure digestion: influence of sodium azide. | 2010 | Bioresour. Technol. | pmid:20728345 |
Guillot M et al. | Dietary chlortetracycline induces differential effects on the accuracy of quantitative computed tomography and dual energy X-ray absorptiometry in assessing vertebral bone mineral density in growing pigs. | 2010 | Vet. J. | pmid:19501002 |
Reinbold JB et al. | The efficacy of three chlortetracycline regimens in the treatment of persistent Anaplasma marginale infection. | 2010 | Vet. Microbiol. | pmid:20346598 |
Chen WR and Huang CH | Adsorption and transformation of tetracycline antibiotics with aluminum oxide. | 2010 | Chemosphere | pmid:20378149 |
Alexander TW et al. | Farm-to-fork characterization of Escherichia coli associated with feedlot cattle with a known history of antimicrobial use. | 2010 | Int. J. Food Microbiol. | pmid:19963297 |
Reinbold JB et al. | Plasma pharmacokinetics of oral chlortetracycline in group fed, ruminating, Holstein steers in a feedlot setting. | 2010 | J. Vet. Pharmacol. Ther. | pmid:20444029 |
Giannetti L et al. | Tetracycline residues in royal jelly and honey by liquid chromatography tandem mass spectrometry: validation study according to Commission Decision 2002/657/EC. | 2010 | Anal Bioanal Chem | pmid:20607522 |
Ji K et al. | Effects of sulfathiazole, oxytetracycline and chlortetracycline on steroidogenesis in the human adrenocarcinoma (H295R) cell line and freshwater fish Oryzias latipes. | 2010 | J. Hazard. Mater. | pmid:20630653 |
Bohnert JA et al. | Optimized Nile Red efflux assay of AcrAB-TolC multidrug efflux system shows competition between substrates. | 2010 | Antimicrob. Agents Chemother. | pmid:20606071 |
Breininger E et al. | Capacitation inducers act through diverse intracellular mechanisms in cryopreserved bovine sperm. | 2010 | Theriogenology | pmid:20580081 |
Brosche S and Backhaus T | Toxicity of five protein synthesis inhibiting antibiotics and their mixture to limnic bacterial communities. | 2010 | Aquat. Toxicol. | pmid:20655118 |
Teixeira Ldos S et al. | Enhancement on the Europium emission band of Europium chlortetracycline complex in the presence of LDL. | 2010 | Anal. Biochem. | pmid:20117070 |
Cháfer-Pericás C et al. | Immunochemical determination of oxytetracycline in fish: comparison between enzymatic and time-resolved fluorometric assays. | 2010 | Anal. Chim. Acta | pmid:20171317 |
Tylová T et al. | High-throughput analysis of tetracycline antibiotics and their epimers in liquid hog manure using Ultra Performance Liquid Chromatography with UV detection. | 2010 | Chemosphere | pmid:20004932 |
Redden RR et al. | Effects of late gestation supplementation of rumen undegradable protein, vitamin E, zinc, and chlortetracycline to ewes on indices of immune transfer and productivity. | 2010 | J. Anim. Sci. | pmid:19966170 |
Lin XM et al. | A novel negative regulation mechanism of bacterial outer membrane proteins in response to antibiotic resistance. | 2010 | J. Proteome Res. | pmid:20718490 |
Cornick NA | Tylosin and chlorotetracycline decrease the duration of fecal shedding of E. coli O157:H7 by swine. | 2010 | Vet. Microbiol. | pmid:20018464 |
Sharma R et al. | Selected antimicrobial resistance during composting of manure from cattle administered sub-therapeutic antimicrobials. | 2009 Mar-Apr | J. Environ. Qual. | pmid:19202027 |
Jones M et al. | Outbreak of Streptococcus equi ssp. zooepidemicus polyserositis in an alpaca herd. | 2009 Jan-Feb | J. Vet. Intern. Med. | pmid:19175745 |
Haghedooren E et al. | Silica-based monolithic columns versus conventional particle-packed columns for liquid chromatographic analysis of tetracycline, oxytetracycline and chlortetracycline. | 2009 | Talanta | pmid:19269409 |
Grasso AN et al. | Optical properties of metacycline, oxytetracycline and chlortetracycline europium complexes in the presence of hydrogen peroxide. | 2009 | J Fluoresc | pmid:19184377 |
Arikan OA et al. | Management of antibiotic residues from agricultural sources: use of composting to reduce chlortetracycline residues in beef manure from treated animals. | 2009 | J. Hazard. Mater. | pmid:18829164 |
Hakuta T et al. | Practical method for the detection of tetracyclines in honey by HPLC and derivative UV-Vis spectra. | 2009 | Anal Sci | pmid:19745545 |
Li HW et al. | Effect of leptin on motility, capacitation and acrosome reaction of human spermatozoa. | 2009 | Int. J. Androl. | pmid:19076257 |
Albaum S and Masaphy S | Comparison of rose bengal-chloramphenicol and modified aureomycin-rose bengal-glucose-peptone agar as media for the enumeration of molds and yeasts in water by membrane filtration techniques. | 2009 | J. Microbiol. Methods | pmid:19111583 |
Bao Y et al. | Depletion of chlortetracycline during composting of aged and spiked manures. | 2009 | Waste Manag | pmid:18954968 |
Grunewald S et al. | Interactions between apoptotic signal transduction and capacitation in human spermatozoa. | 2009 | Hum. Reprod. | pmid:19443455 |
Baqi Y et al. | High-affinity, non-nucleotide-derived competitive antagonists of platelet P2Y12 receptors. | 2009 | J. Med. Chem. | pmid:19463000 |
Arikan O et al. | Minimally managed composting of beef manure at the pilot scale: effect of manure pile construction on pile temperature profiles and on the fate of oxytetracycline and chlortetracycline. | 2009 | Bioresour. Technol. | pmid:19450976 |
Werner JJ et al. | Photolysis of chlortetracycline on a clay surface. | 2009 | J. Agric. Food Chem. | pmid:19591472 |
Brooks SP et al. | In-feed administered sub-therapeutic chlortetracycline alters community composition and structure but not the abundance of community resistance determinants in the fecal flora of the rat. | 2009 | Anaerobe | pmid:19655426 |
Finkel S and Sullivan BH | Primary atypical pneumonia: an analysis of one hundred twenty-three cases; report of one fatality; review of fourteen cases treated with aureomycin. 1952. | 2009 | Chest | pmid:20162754 |
Chénier MR and Juteau P | Fate of chlortetracycline- and tylosin-resistant bacteria in an aerobic thermophilic sequencing batch reactor treating swine waste. | 2009 | Microb. Ecol. | pmid:19125305 |
Liu F et al. | Effects of six selected antibiotics on plant growth and soil microbial and enzymatic activities. | 2009 | Environ. Pollut. | pmid:19157661 |