chlortetracycline is a lipid of Polyketides (PK) class. Chlortetracycline is associated with abnormalities such as Granulomatous Disease, Chronic, Infection, Ischemia, Cerebral Ischemia and Cerebral Infarction. The involved functions are known as Regulation, Binding (Molecular Function), Agent, Stimulus and Process. Chlortetracycline often locates in Protoplasm, Plasma membrane, Membrane, Cytoplasm and specific granule. The associated genes with chlortetracycline are FPR1 gene, P4HTM gene, Homologous Gene, HIST1H1C gene and Microbiome. The related lipids are Lysophosphatidylcholines, Sterols, dilauroyl lecithin, seminolipid and Total cholesterol. The related experimental models are Mouse Model.
To understand associated biological information of chlortetracycline, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
chlortetracycline is suspected in Ischemia, Cerebral Ischemia, Cerebral Infarction, Granulomatous Disease, Chronic, Infection, Antibiotic resistant infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with chlortetracycline
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'Chlortetracycline and demeclocycline inhibit calpains and protect mouse neurons against glutamate toxicity and cerebral ischemia.' (Jiang SX et al., 2005).
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Authors | Title | Published | Journal | PubMed Link |
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Jukes TH | Public health significance of feeding low levels of antibiotics to animals. | 1973 | Adv. Appl. Microbiol. | pmid:4584679 |
Cunningham MP | Immunization of cattle against Theileria parva. | 1977 | Adv. Exp. Med. Biol. | pmid:596297 |
Takeshige K et al. | Release of the membrane-calcium and its relation to the superoxide formation by polymorphonuclear leukocytes. | 1982 | Adv. Exp. Med. Biol. | pmid:6283837 |
Purnell RE | East Coast fever: some recent research in East Africa. | 1977 | Adv. Parasitol. | pmid:326011 |
Dumas M et al. | [Nervous system mycoses in Senegal]. | 1973 | Afr J Med Sci | pmid:4584122 |
Pearce FL et al. | Histamine secretion from mast cells treated with chlortetracycline (aureomycin): a novel calcium ionophore. | 1983 | Agents Actions | pmid:6191538 |
WoldeMussie E and Moran NC | Histamine release by compound 48/80: evidence for the depletion and repletion of calcium using chlortetracycline and 45calcium. | 1984 | Agents Actions | pmid:6084410 |
Madej J and Davidjuk V | [Treatment with tetracyclines and vitamin A of papillomatous changes in the external sex organs]. | 1973 | Akush Ginekol (Mosk) | pmid:4761883 |
TURANOVA EN et al. | [STUDY OF THE CAUSES AND PECULIARITIES OF THE CLINICAL COURSE OF CHRONIC GONORRHEA IN WOMEN]. | 1963 Nov-Dec | Akush Ginekol (Mosk) | pmid:14148729 |
BARKALAIA AI and CHERNUKH AM | [ON THE PROBLEM OF THE POSSIBILITIES OF TRANSPLACENTAL CHEMOTHERAPY OF THE FETUS WITH ANTIBIOTICS FROM THE TETRACYCLINE GROUP]. | 1963 Sep-Oct | Akush Ginekol (Mosk) | pmid:14085745 |