chlortetracycline is a lipid of Polyketides (PK) class. Chlortetracycline is associated with abnormalities such as Granulomatous Disease, Chronic, Infection, Ischemia, Cerebral Ischemia and Cerebral Infarction. The involved functions are known as Regulation, Binding (Molecular Function), Agent, Stimulus and Process. Chlortetracycline often locates in Protoplasm, Plasma membrane, Membrane, Cytoplasm and specific granule. The associated genes with chlortetracycline are FPR1 gene, P4HTM gene, Homologous Gene, HIST1H1C gene and Microbiome. The related lipids are Lysophosphatidylcholines, Sterols, dilauroyl lecithin, seminolipid and Total cholesterol. The related experimental models are Mouse Model.
To understand associated biological information of chlortetracycline, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
chlortetracycline is suspected in Ischemia, Cerebral Ischemia, Cerebral Infarction, Granulomatous Disease, Chronic, Infection, Antibiotic resistant infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with chlortetracycline
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'Chlortetracycline and demeclocycline inhibit calpains and protect mouse neurons against glutamate toxicity and cerebral ischemia.' (Jiang SX et al., 2005).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Fuska J et al. | Biotransformation of benzyl thiocyanate by Streptomyces aureofaciens. | 1994 | Lett. Appl. Microbiol. | pmid:7765389 |
Astarie-Dequeker C et al. | Endothelin-3 reduces Ca(2+)-uptake and Ca2+ content of platelet internal stores. | 1995 | Biochem. Biophys. Res. Commun. | pmid:7763261 |
ZakrevskiÄ VI et al. | [Polyamines in microorganisms sensitive and resistant to antibiotics]. | 1976 | Antibiotiki | pmid:776080 |
Maxwell CV et al. | Effect of dietary chlortetracycline during breeding and(or) farrowing and lactation on reproductive performance of sows: a cooperative study. S-145 Committee on Nutritional Systems for Swine to Increase Reproductive Efficiency. | 1994 | J. Anim. Sci. | pmid:7759367 |
Shi QX and Roldan ER | Bicarbonate/CO2 is not required for zona pellucida- or progesterone-induced acrosomal exocytosis of mouse spermatozoa but is essential for capacitation. | 1995 | Biol. Reprod. | pmid:7756449 |
Kisker C et al. | The complex formed between Tet repressor and tetracycline-Mg2+ reveals mechanism of antibiotic resistance. | 1995 | J. Mol. Biol. | pmid:7707374 |
Kiser JS | A perspective on the use of antibiotics in animal feeds. | 1976 | J. Anim. Sci. | pmid:770412 |
Nguyen-Van-Ai et al. | [Bacteriological and epidemiological considerations on shigelloses in South Vietnam (1969-1973)]. | 1975 May-Jun | Bull Soc Pathol Exot Filiales | pmid:770024 |
Ellington JE et al. | Binding of stallion spermatozoa to the equine zona pellucida after coculture with oviductal epithelial cells. | 1993 | J. Reprod. Fertil. | pmid:7688425 |
Dairi T et al. | Conserved organization of genes for biosynthesis of chlortetracycline in Streptomyces strains. | 1995 | Biosci. Biotechnol. Biochem. | pmid:7670200 |