chlortetracycline is a lipid of Polyketides (PK) class. Chlortetracycline is associated with abnormalities such as Granulomatous Disease, Chronic, Infection, Ischemia, Cerebral Ischemia and Cerebral Infarction. The involved functions are known as Regulation, Binding (Molecular Function), Agent, Stimulus and Process. Chlortetracycline often locates in Protoplasm, Plasma membrane, Membrane, Cytoplasm and specific granule. The associated genes with chlortetracycline are FPR1 gene, P4HTM gene, Homologous Gene, HIST1H1C gene and Microbiome. The related lipids are Lysophosphatidylcholines, Sterols, dilauroyl lecithin, seminolipid and Total cholesterol. The related experimental models are Mouse Model.
To understand associated biological information of chlortetracycline, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
chlortetracycline is suspected in Ischemia, Cerebral Ischemia, Cerebral Infarction, Granulomatous Disease, Chronic, Infection, Antibiotic resistant infection and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with chlortetracycline
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
Mouse Model are used in the study 'Chlortetracycline and demeclocycline inhibit calpains and protect mouse neurons against glutamate toxicity and cerebral ischemia.' (Jiang SX et al., 2005).
Model | Cross reference | Weighted score | Related literatures |
---|
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Levesque CL et al. | Alterations in ileal mucosa bacteria related to diet complexity and growth performance in young pigs. | 2014 | PLoS ONE | pmid:25247930 |
Washburn K et al. | Pharmacokinetics of oral chlortetracycline in nonpregnant adult ewes. | 2014 | J. Vet. Pharmacol. Ther. | pmid:25131164 |
Kanwar N et al. | Impact of treatment strategies on cephalosporin and tetracycline resistance gene quantities in the bovine fecal metagenome. | 2014 | Sci Rep | pmid:24872333 |
Kodimalar K et al. | A survey of chlortetracycline concentration in feed and its residue in chicken egg in commercial layer farms. | 2014 | J. Biosci. | pmid:24845506 |
Holman DB and Chénier MR | Temporal changes and the effect of subtherapeutic concentrations of antibiotics in the gut microbiota of swine. | 2014 | FEMS Microbiol. Ecol. | pmid:25187398 |
Raspor LainÅ¡Äek P et al. | Implementation of the Bacillus cereus microbiological plate used for the screening of tetracyclines in raw milk samples with STAR protocol - the problem with false-negative results solved. | 2014 | Food Addit Contam Part A Chem Anal Control Expo Risk Assess | pmid:25230820 |
Chen C et al. | Occurrence of antibiotics and antibiotic resistances in soils from wastewater irrigation areas in Beijing and Tianjin, China. | 2014 | Environ. Pollut. | pmid:25016103 |
Lin XM et al. | Decreased expression of LamB and Odp1 complex is crucial for antibiotic resistance in Escherichia coli. | 2014 | J Proteomics | pmid:24412198 |
Chen X et al. | A novel electrochemiluminescence tetracyclines sensor based on a Ru(bpy)₃²âº-doped silica nanoparticles/Nafion film modified electrode. | 2014 | Talanta | pmid:25127561 |
Fang H et al. | Microbial response to repeated treatments of manure containing sulfadiazine and chlortetracycline in soil. | 2014 | J Environ Sci Health B | pmid:24901964 |
Chang BV et al. | Biodegradation of three tetracyclines in swine wastewater. | 2014 | J Environ Sci Health B | pmid:24762183 |
Agga GE et al. | Effects of chlortetracycline and copper supplementation on antimicrobial resistance of fecal Escherichia coli from weaned pigs. | 2014 | Prev. Vet. Med. | pmid:24655578 |
Ma Y et al. | Preparation of a novel magnetic microporous adsorbent and its adsorption behavior of p-nitrophenol and chlorotetracycline. | 2014 | J. Hazard. Mater. | pmid:24380891 |
Cazer CL et al. | Use of pharmacokinetic modeling to assess antimicrobial pressure on enteric bacteria of beef cattle fed chlortetracycline for growth promotion, disease control, or treatment. | 2014 | Foodborne Pathog. Dis. | pmid:24588058 |
Marosevic D et al. | In vivo spread of macrolide-lincosamide-streptogramin B (MLSB) resistance--a model study in chickens. | 2014 | Vet. Microbiol. | pmid:24467930 |
Liu M et al. | Feasibility of conventional and single-stage anaerobic ammonium oxidation processes for treating chlortetracycline wastewater. | 2014 | Water Sci. Technol. | pmid:25259481 |
Daghrir R et al. | Removal of chlortetracycline from spiked municipal wastewater using a photoelectrocatalytic process operated under sunlight irradiations. | 2014 | Sci. Total Environ. | pmid:23911841 |
Lin X et al. | Fluctuation of multiple metabolic pathways is required for Escherichia coli in response to chlortetracycline stress. | 2014 | Mol Biosyst | pmid:24510206 |
Shimshoni JA et al. | Acute maduramicin toxicosis in pregnant gilts. | 2014 | Food Chem. Toxicol. | pmid:24705019 |
Khan MH et al. | Chlortetracycline degradation by photocatalytic ozonation in the aqueous phase: mineralization and the effects on biodegradability. | 2013 Jan-Feb | Environ Technol | pmid:23530364 |
Musdal Y et al. | FDA-approved drugs and other compounds tested as inhibitors of human glutathione transferase P1-1. | 2013 | Chem. Biol. Interact. | pmid:23769903 |
Wei L et al. | Novel inhibitors of protein arginine deiminase with potential activity in multiple sclerosis animal model. | 2013 | J. Med. Chem. | pmid:23421315 |
Kaiser M et al. | Treatment of shoulder ulcers in sows - rubber mats and zinc ointment compared to chlortetracycline spray. | 2013 | Acta Vet. Scand. | pmid:23414554 |
Ridley EV et al. | Microbe-dependent and nonspecific effects of procedures to eliminate the resident microbiota from Drosophila melanogaster. | 2013 | Appl. Environ. Microbiol. | pmid:23475620 |
Zhu T et al. | Deciphering and engineering of the final step halogenase for improved chlortetracycline biosynthesis in industrial Streptomyces aureofaciens. | 2013 | Metab. Eng. | pmid:23800859 |
Cabral RG et al. | Effects of lasalocid and intermittent feeding of chlortetracycline on the growth of prepubertal dairy heifers. | 2013 | J. Dairy Sci. | pmid:23684035 |
Ded L et al. | In vivo exposure to 17β-estradiol triggers premature sperm capacitation in cauda epididymis. | 2013 | Reproduction | pmid:23319664 |
VMD revises advice on chlortetracyline use in calf milk replacer. | 2013 | Vet. Rec. | pmid:23335679 | |
Cottell JL et al. | blaCTX-M-32 on an IncN plasmid in Escherichia coli from beef cattle in the United States. | 2013 | Antimicrob. Agents Chemother. | pmid:23165469 |
Goossens J et al. | Chronic exposure to the mycotoxin T-2 promotes oral absorption of chlortetracycline in pigs. | 2013 | J. Vet. Pharmacol. Ther. | pmid:23701633 |
Xiao D et al. | Effects of dietary administering chitosan on growth performance, jejunal morphology, jejunal mucosal sIgA, occludin, claudin-1 and TLR4 expression in weaned piglets challenged by enterotoxigenic Escherichia coli. | 2013 | Int. Immunopharmacol. | pmid:24007779 |
Hawker DW et al. | Uptake of zwitterionic antibiotics by rice (Oryza sativa L.) in contaminated soil. | 2013 | J. Hazard. Mater. | pmid:24231322 |
Kennedy D | Time to deal with antibiotics. | 2013 | Science | pmid:24233692 |
Robbins RC et al. | Effects of quaternary benzo(c)phenanthridine alkaloids on growth performance, shedding of organisms, and gastrointestinal tract integrity in pigs inoculated with multidrug-resistant Salmonella spp. | 2013 | Am. J. Vet. Res. | pmid:24274891 |
Schultz N and Capion N | Efficacy of salicylic acid in the treatment of digital dermatitis in dairy cattle. | 2013 | Vet. J. | pmid:24268474 |
McDonald J | Chlortetracycline in calf milk replacer. | 2013 | Vet. Rec. | pmid:24057498 |
Hager D et al. | Total synthesis of herbicidin C and aureonuclemycin: impasses and new avenues. | 2013 | J. Org. Chem. | pmid:24074399 |
Daghrir R et al. | Electrochemical degradation of chlortetracycline using N-doped Ti/TiO2 photoanode under sunlight irradiations. | 2013 | Water Res. | pmid:24075724 |
Yang XQ et al. | Zeolite imidazolate framework-8 as sorbent for on-line solid-phase extraction coupled with high-performance liquid chromatography for the determination of tetracyclines in water and milk samples. | 2013 | J Chromatogr A | pmid:23870544 |
Murillo PulgarÃn JA et al. | Simultaneous determination of doxycycline and chlortetracycline in real samples by europium-sensitized luminescence. | 2013 | Appl Spectrosc | pmid:23601536 |
Kanwar N et al. | Effects of ceftiofur and chlortetracycline treatment strategies on antimicrobial susceptibility and on tet(A), tet(B), and bla CMY-2 resistance genes among E. coli isolated from the feces of feedlot cattle. | 2013 | PLoS ONE | pmid:24260423 |
Holman DB and Chénier MR | Impact of subtherapeutic administration of tylosin and chlortetracycline on antimicrobial resistance in farrow-to-finish swine. | 2013 | FEMS Microbiol. Ecol. | pmid:23397987 |
Juntunen P et al. | Absence of tetracycline resistance in Campylobacter coli isolates from Finnish finishing pigs treated with chlortetracycline. | 2013 | J. Appl. Microbiol. | pmid:23282197 |
Shepelevich VV et al. | [Sensitivity of Pseudomonas chlororaphis to antibiotics and chemical tools of plant protection]. | 2012 Nov-Dec | Mikrobiol. Z. | pmid:23293823 |
Guo L et al. | Development and validation of a liquid chromatographic/ tandem mass spectrometric method for determination of chlortetracycline, oxytetracycline, tetracycline, and doxycycline in animal feeds. | 2012 Jul-Aug | J AOAC Int | pmid:22970565 |
Del Pozo Sacristán R et al. | Efficacy of in-feed medication with chlortetracycline in a farrow-to-finish herd against a clinical outbreak of respiratory disease in fattening pigs. | 2012 Dec 22-29 | Vet. Rec. | pmid:23136309 |
Tong ZL et al. | [Anaerobic digestion of animal manure contaminated by tetracyclines]. | 2012 | Huan Jing Ke Xue | pmid:22624404 |
Anadón A et al. | Plasma disposition and tissue depletion of chlortetracycline in the food producing animals, chickens for fattening. | 2012 | Food Chem. Toxicol. | pmid:22595330 |
Chi Z and Liu R | New insights into the characterization of the binding of tetracycline analogues with lysozyme: a biophysical study. | 2012 | Chemosphere | pmid:22014467 |
Gao YY et al. | Treatment of ocular itching associated with ocular demodicosis by 5% tea tree oil ointment. | 2012 | Cornea | pmid:21955627 |
Pérez Aguirreburualde MS et al. | Acrosin activity regulation by protein kinase C and tyrosine kinase in bovine sperm acrosome exocytosis induced by lysophosphatidylcholine. | 2012 | Reprod. Domest. Anim. | pmid:22335484 |
Varel VH et al. | Effect of anaerobic digestion temperature on odour, coliforms and chlortetracycline in swine manure or monensin in cattle manure. | 2012 | J. Appl. Microbiol. | pmid:22313722 |
Guo RX and Chen JQ | Phytoplankton toxicity of the antibiotic chlortetracycline and its UV light degradation products. | 2012 | Chemosphere | pmid:22341398 |
Selvam A et al. | Composting of swine manure spiked with sulfadiazine, chlortetracycline and ciprofloxacin. | 2012 | Bioresour. Technol. | pmid:22261658 |
Lin X et al. | Differential regulation of OmpC and OmpF by AtpB in Escherichia coli exposed to nalidixic acid and chlortetracycline. | 2012 | J Proteomics | pmid:22960566 |
Liu F et al. | Changes in functional diversity of soil microbial community with addition of antibiotics sulfamethoxazole and chlortetracycline. | 2012 | Appl. Microbiol. Biotechnol. | pmid:22205443 |
Shelver WL and Varel VH | Development of a UHPLC-MS/MS method for the measurement of chlortetracycline degradation in swine manure. | 2012 | Anal Bioanal Chem | pmid:22207281 |
Poole TL et al. | Competitive effect of commensal faecal bacteria from growing swine fed chlortetracycline-supplemented feed on β-haemolytic Escherichia coli strains with multiple antimicrobial resistance plasmids. | 2012 | J. Appl. Microbiol. | pmid:22716900 |
Wang YX et al. | [Synthesis of core/shell structured magnetic carbon nanoparticles and its adsorption ability to chlortetracycline in aquatic environment]. | 2012 | Huan Jing Ke Xue | pmid:22720571 |
Li Z et al. | Determination on the binding of chlortetracycline to bovine serum albumin using spectroscopic methods. | 2012 | J. Biochem. Mol. Toxicol. | pmid:22730061 |
Kim TH et al. | Degradation and toxicity assessment of sulfamethoxazole and chlortetracycline using electron beam, ozone and UV. | 2012 | J. Hazard. Mater. | pmid:22682797 |
Wang LQ et al. | A molecularly imprinted photonic polymer sensor with high selectivity for tetracyclines analysis in food. | 2012 | Analyst | pmid:22705906 |
Hager D et al. | Stereoselective total syntheses of herbicidin C and aureonuclemycin through late-stage glycosylation. | 2012 | Angew. Chem. Int. Ed. Engl. | pmid:22644891 |
Dong L et al. | DNA damage and biochemical toxicity of antibiotics in soil on the earthworm Eisenia fetida. | 2012 | Chemosphere | pmid:22647195 |
Chen Y et al. | Photolysis of chlortetracycline in aqueous solution: kinetics, toxicity and products. | 2012 | J Environ Sci (China) | pmid:22655385 |
Lin D et al. | Physiological and molecular responses of the earthworm (Eisenia fetida) to soil chlortetracycline contamination. | 2012 | Environ. Pollut. | pmid:22868346 |
Liu X et al. | Potentials and mechanisms of genotoxicity of six pharmaceuticals frequently detected in freshwater environment. | 2012 | Toxicol. Lett. | pmid:22450446 |
Wen B et al. | Toxic effects of chlortetracycline on maize growth, reactive oxygen species generation and the antioxidant response. | 2012 | J Environ Sci (China) | pmid:23505878 |
Yin CY et al. | [Pollution characteristics and accumulation of antibiotics in typical protected vegetable soils]. | 2012 | Huan Jing Ke Xue | pmid:23213909 |
Strait EL et al. | Dysgalactia associated with Mycoplasma suis infection in a sow herd. | 2012 | J. Am. Vet. Med. Assoc. | pmid:23216044 |
Levesque CL et al. | Ileal mucosa-associated--but not ileal digesta--bacterial profiles in grower pigs are influenced by nutrition and use of antibiotics for weaner pigs. | 2012 | J. Anim. Sci. | pmid:23365406 |
Dai M et al. | In vitro development and transfer of resistance to chlortetracycline in Bacillus subtilis. | 2012 | J. Microbiol. | pmid:23124749 |
Dreher TM et al. | Effects of chlortetracycline amended feed on anaerobic sequencing batch reactor performance of swine manure digestion. | 2012 | Bioresour. Technol. | pmid:23023238 |
Wang P et al. | Heterologous expression and manipulation of three tetracycline biosynthetic pathways. | 2012 | Angew. Chem. Int. Ed. Engl. | pmid:23024027 |
Kadirvel G et al. | Effect of cryopreservation on apoptotic-like events and its relationship with cryocapacitation of buffalo (Bubalus bubalis) sperm. | 2012 | Reprod. Domest. Anim. | pmid:21676035 |
Zhang C et al. | Validation of Polo-like kinase 1 as a therapeutic target in pancreatic cancer cells. | 2012 | Cancer Biol. Ther. | pmid:22892842 |
Wang X et al. | Dietary supplementation with the probiotic Lactobacillus fermentum I5007 and the antibiotic aureomycin differentially affects the small intestinal proteomes of weanling piglets. | 2012 | J. Nutr. | pmid:22113866 |
Daghrir R et al. | Photoelectrocatalytic degradation of chlortetracycline using Ti/TiO2 nanostructured electrodes deposited by means of a Pulsed Laser Deposition process. | 2012 | J. Hazard. Mater. | pmid:22104083 |
Pakpour S et al. | Frequency of antibiotic resistance in a swine facility 2.5 years after a ban on antibiotics. | 2012 | Microb. Ecol. | pmid:21997543 |
Rérat M et al. | Bovine respiratory disease: efficacy of different prophylactic treatments in veal calves and antimicrobial resistance of isolated Pasteurellaceae. | 2012 | Prev. Vet. Med. | pmid:21945813 |
Apley MD et al. | Use estimates of in-feed antimicrobials in swine production in the United States. | 2012 | Foodborne Pathog. Dis. | pmid:22324295 |
Bachmann S et al. | Replacement of calcium for strontium in hamster sperm incubation media: effect on sperm function. | 2012 | Mol. Hum. Reprod. | pmid:21933847 |
Kim HY et al. | Biochemical effects of veterinary antibiotics on proliferation and cell cycle arrest of human HEK293 cells. | 2012 | Bull Environ Contam Toxicol | pmid:22673765 |
Kim KR et al. | Decline in extractable antibiotics in manure-based composts during composting. | 2012 | Waste Manag | pmid:21865024 |
Chi Z et al. | Binding of tetracycline and chlortetracycline to the enzyme trypsin: spectroscopic and molecular modeling investigations. | 2011 | PLoS ONE | pmid:22205948 |
Nelson ML and Levy SB | The history of the tetracyclines. | 2011 | Ann. N. Y. Acad. Sci. | pmid:22191524 |
Duggar BM | Aureomycin: a product of the continuing search for new antibiotics. | 2011 | Ann. N. Y. Acad. Sci. | pmid:22191532 |
Zhang D et al. | Strong adsorption of chlorotetracycline on magnetite nanoparticles. | 2011 | J. Hazard. Mater. | pmid:21724321 |
Stone JJ et al. | Impact of chlortetracycline on sequencing batch reactor performance for swine manure treatment. | 2011 | Bioresour. Technol. | pmid:21724384 |
Guillot M et al. | In growing pigs, chlortetracycline induces a reversible green bone discoloration and a persistent increase of bone mineral density dependent of dosing regimen. | 2011 | Res. Vet. Sci. | pmid:20723952 |
Kato Y et al. | Capacitation status of activated bovine sperm cultured in media containing methyl-β-cyclodextrin affects the acrosome reaction and fertility. | 2011 | Zygote | pmid:20727245 |
Wu RB et al. | Prevalence and diversity of class 1 integrons and resistance genes in antimicrobial-resistant Escherichia coli originating from beef cattle administered subtherapeutic antimicrobials. | 2011 | J. Appl. Microbiol. | pmid:21645183 |
Volkers G et al. | Recognition of drug degradation products by target proteins: isotetracycline binding to Tet repressor. | 2011 | J. Med. Chem. | pmid:21699184 |
Bernabò N et al. | The role of actin in capacitation-related signaling: an in silico and in vitro study. | 2011 | BMC Syst Biol | pmid:21450097 |
Miah AG et al. | Intracellular signaling cascades induced by relaxin in the stimulation of capacitation and acrosome reaction in fresh and frozen-thawed bovine spermatozoa. | 2011 | Anim. Reprod. Sci. | pmid:21493019 |
Miyata M et al. | Electrochemical oxidation of tetracycline antibiotics using a Ti/IrO2 anode for wastewater treatment of animal husbandry. | 2011 | Water Sci. Technol. | pmid:21278467 |
Ni Y et al. | Spectrophotometric study of the interaction between chlorotetracycline and bovine serum albumin using Eosin Y as site marker with the aid of chemometrics. | 2011 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:21163687 |
Mirshokraei P et al. | Pentoxifylline induces capacitation and acrosome reaction and improves quality of motility in canine ejaculated spermatozoa. | 2011 | Res. Vet. Sci. | pmid:21324497 |
Alexander TW et al. | Longitudinal characterization of antimicrobial resistance genes in feces shed from cattle fed different subtherapeutic antibiotics. | 2011 | BMC Microbiol. | pmid:21261985 |
Griffin MO et al. | Tetracycline compounds with non-antimicrobial organ protective properties: possible mechanisms of action. | 2011 | Pharmacol. Res. | pmid:20951211 |