chlortetracycline is a lipid of Polyketides (PK) class. Chlortetracycline is associated with abnormalities such as Granulomatous Disease, Chronic, Infection, Ischemia, Cerebral Ischemia and Cerebral Infarction. The involved functions are known as Regulation, Binding (Molecular Function), Agent, Stimulus and Process. Chlortetracycline often locates in Protoplasm, Plasma membrane, Membrane, Cytoplasm and specific granule. The associated genes with chlortetracycline are FPR1 gene, P4HTM gene, Homologous Gene, HIST1H1C gene and Microbiome. The related lipids are Lysophosphatidylcholines, Sterols, dilauroyl lecithin, seminolipid and Total cholesterol. The related experimental models are Mouse Model.
To understand associated biological information of chlortetracycline, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
chlortetracycline is suspected in Ischemia, Cerebral Ischemia, Cerebral Infarction, Granulomatous Disease, Chronic, Infection, Antibiotic resistant infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with chlortetracycline
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'Chlortetracycline and demeclocycline inhibit calpains and protect mouse neurons against glutamate toxicity and cerebral ischemia.' (Jiang SX et al., 2005).
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Authors | Title | Published | Journal | PubMed Link |
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MAKAREVICH MG and LAZNIKOVA TN | [Significance of phosphorus in biosynthesis of chlortetracycline]. | 1959 Jan-Feb | Antibiotiki (Mosc) | pmid:24545224 |
ALEUTSKII NN | [Effect of biomycin on Sechenov's inhibition]. | 1959 Jul-Aug | Farmakol Toksikol | pmid:13792573 |
CHERNUKH AM and BALASHOVA VA | [On the problem of the effect of chlortetracycline and tetracycline on iron cotent in the blood serum]. | 1959 Jul-Aug | Antibiotiki | pmid:13809691 |
STARSHOV PD | [Prevention of riboflavin-deficiency appearing during chlortetracycline therapy of patients with acute dysentery]. | 1959 Jul-Aug | Antibiotiki | pmid:13833867 |
MIRONOV GS et al. | [Effect of chlortetracyline on the level of bilirubin and cholesterol in the blood serum in patients with acute bacillary dysentery]. | 1959 Jul-Aug | Antibiotiki | pmid:14422865 |
ROKOS J et al. | [Effect of chlortetracycline on the activity of alpha-amylases]. | 1959 Jul-Aug | Antibiotiki | pmid:14438489 |
SOLNTSEV KM | [Assay of the preparation aurkorm-2]. | 1959 Mar-Apr | Antibiotiki (Mosc) | pmid:24545308 |
ERMOLVEVA ZV et al. | [Intramuscular injections of chlortetracycline with ecmoline and oral administration of tetracycline tablets in therapy of influenza and its complications in children]. | 1959 May-Jun | Antibiotiki (Mosc) | pmid:24545348 |
BYKOVA MA and AVER'IANOVA LL | [A method for the determination of chloretracycline concentrations in liquids, organs and tissues of animals with the aid of paper disks]. | 1959 Nov-Dec | Antibiotiki | pmid:13806624 |
MAKAROVSKAIA LN et al. | [Therapeutic activity of chlortetracycline in experimental plague caused by streptomycin resistant and sensitive strains of Pasteurella pestis]. | 1959 Nov-Dec | Antibiotiki | pmid:14420134 |
EGOROV NS and BARANOVA IP | [Effect of p-dimethylaminobenzaldehyde on chlortetracycline synthesis]. | 1959 Sep-Oct | Antibiotiki | pmid:13819549 |
SHENG ST and CHEN CP | [The effect of orthoihosphate on the pathways of carbohydrate metabolism in Streptomyces aureofaciens in connection with the synthesis of chlortetracycline]. | 1959 Sep-Oct | Antibiotiki | pmid:14445815 |
SHUL'GA IV | [On the problem of treatment of blepharitis with biomycin]. | 1959 Sep-Oct | Vestn Oftalmol | pmid:14446294 |
HEROLD M et al. | [The influence of benzyl thiocyanate on the synthesis of chlortetracycline after direct enrichment by ground barley]. | 1959 Sep-Oct | Antibiotiki | pmid:14401316 |
BOGER WP and GAVIN JJ | Demethylchlortetracycline: serum concentration studies and cerebrospinal fluid diffusion. | 1959-1960 | Antibiot Annu | pmid:13802119 |
CHAVEZ MAX G | Therapeutic evaluation of demethylchlorte-tracycline in human brucellosis. | 1959-1960 | Antibiot Annu | pmid:13809530 |
DUKE CJ et al. | Demethylchlortetracycline in the treatment of pneumonia. | 1959-1960 | Antibiot Annu | pmid:13818530 |
FUJII R et al. | Clinical results with demethylchlortetracycline in pediatrics in Japan and comparative studies with other tetracyclines. | 1959-1960 | Antibiot Annu | pmid:13825576 |
GARSON W et al. | Preliminary report on the effect of dextrosulphenidol in experimental syphilis. | 1959-1960 | Antibiot Annu | pmid:13826688 |
STOKSTAD EL et al. | The effect of calcium salts on chlortetracycline absorption. | 1959-1960 | Antibiot Annu | pmid:13834851 |
VINEYARD JP et al. | Clinical and laboratory evaluation of demethylchlortetracycline. | 1959-1960 | Antibiot Annu | pmid:13842376 |
FINLAND M et al. | Observations on demethylchlortetracycline. | 1959-1960 | Antibiot Annu | pmid:13822922 |
MARMELL M and PRIGOT A | The therapeutic value of demethyl-chlortetracycline in gonorrhea, lymphogranuloma venerum, and donovanosis. | 1959-1960 | Antibiot Annu | pmid:14421357 |
PERRY DM et al. | Demethylchloretracy cline: a clinical and laboratory appraisal. | 1959-1960 | Antibiot Annu | pmid:14432023 |
ROBERTS MS et al. | Demethylchlortetracycline in genitourinary infections. | 1959-1960 | Antibiot Annu | pmid:14437829 |
ROSS S et al. | Absorption of demethyl-chlortetracycline in children: some preliminary observations. | 1959-1960 | Antibiot Annu | pmid:14439180 |
KANOF NB and BLAU S | Oral demethylchloretetracycline in the treatment of pustular dermatoses. | 1959-1960 | Antibiot Annu | pmid:14404320 |
OLARTE J | The sensitivity of selected strains of Shigella, Salmonella, and enteropathogenic Escherichia coli to demethylchlortetracycline and tetracycline. | 1959-1960 | Antibiot Annu | pmid:14428591 |
GIBBONS RJ and REICHELDERFER TE | Transplacental transmission of demethylchlortetracycline and toxicity studies in premature and full term, newly born infants. | 1960 | Antibiotic Med Clin Ther (New York) | pmid:13705067 |
GUGGENHEIM K et al. | Effect of dietary carbohydrates and aureomycin on serum and liver cholesterol in rats. | 1960 | J. Nutr. | pmid:13709524 |
HOWE EE and BOSSHARDT DK | Antibiotics and plasma cholesterol in the mouse. | 1960 | J. Nutr. | pmid:13716253 |
HOWE EE and BOSSHARDT DK | Further studies on the effect of chlortetracycline on plasma cholesterol of the weanling mouse. | 1960 | J. Nutr. | pmid:13716254 |
IACHEVA Z | [Effect of fruit juices on the activity of penicillin, streptomycin and biomycin]. | 1960 | Izv Mikrobiol Inst (Sofiia) | pmid:13717188 |
WOZNIAK LA | Studies on binding of tetracyclines by dog and human plasma. | 1960 | Proc. Soc. Exp. Biol. Med. | pmid:13786737 |
ZOELLNER N and PARRISIUS G | [Photodynamic reactions after administration of demethylchlortetracycline]. | 1960 | Med Welt | pmid:13788725 |
ALEXANDER B | Effect of chlortetracycline on vitamin B6 and amino acid decarboxylase in bacteria from the alimentary tract of the chick. | 1960 | Appl Microbiol | pmid:13792578 |
ASNIN DI and SUTEEVA TG | [Treatment of cervico-facial actinomycosis with biomycin (chlortetracycline)]. | 1960 | Sov Med | pmid:13794830 |
BALSANO F et al. | [First observations on the use of demethylchlorotetracycline in phlogoses of the urinary tract]. | 1960 | Minerva Med. | pmid:13796322 |
CHAMPIGNY O et al. | [Influence of aureomycin on the ponderal growth and duration of survival of the adrenalectomized rat]. | 1960 | Arch Sci Physiol (Paris) | pmid:13809086 |
CLAPPER WE and PROPER R | Comparative activity of demethyl-chlortetracycline and tetracycline against organisms commonly encountered in clinical material. | 1960 | Antibiot Chemother (Northfield) | pmid:13810415 |
DOROSHOW LW and ABESHOUSE BS | Criteria for the evaluation of therapeutic agents in the treatment of urinary tract infections. I. 6-demethyl-chlortetracycline. | 1960 | Sinai Hosp J (Balt) | pmid:13817712 |
FENNER O | [Demethylchlortetracycline (ledermycin). Comparative bacteriological research]. | 1960 | Med Welt | pmid:13822177 |
EYME P | [Demethylchlortetracycline/Ledermycin (DMCTC). Clinico-therapeutic results]. | 1960 | Med Welt | pmid:13697717 |
FAERMAN NN | [The use of biomycin in the treatment of patients with pharyngeal diphtheria]. | 1960 | Zh. Mikrobiol. Epidemiol. Immunobiol. | pmid:13697864 |
SAVITSKAIA EP | [Comparative effects of biomycin and sekazin on Rickettsia prowazekii and mooseri]. | 1960 | Zh. Mikrobiol. Epidemiol. Immunobiol. | pmid:13746919 |
WORLEY DE and HANSEN MF | Chemotherapeutic studies of gastrointestinal parasites of beef cattle and bison in Kansa. | 1960 | Am. J. Vet. Res. | pmid:13845988 |
ZATULOVS'KYI BH | [Comparative studies of the effect of furacillin, levomycetin and biomycin on dysenterial bacilli]. | 1960 | Mikrobiol Zh | pmid:13847084 |
HALL RH and GALE GO | Augmentation of chlortetracycline activity against two strains of Staphylococcus by kinetin. | 1960 | Proc. Soc. Exp. Biol. Med. | pmid:13848399 |
BRECHT W | [Clinical experiences with a new tetracycline preparation]. | 1960 | Med Welt | pmid:13855582 |
MACFADDEN DL et al. | Mode of action of antibiotics in the nutrition of the dairy calf. IV. Phagocytosis of antibiotic-resistant strains of Escherichia coli. | 1960 | J. Bacteriol. | pmid:13764769 |
MALAMOS B et al. | [In vitro sensitivity of various pathogenic organisms to the 4 tetracyclines demethylchlortetracycline, chlortetracycline, oxytetracycline and tetracycline]. | 1960 | Z Mikrosk Anat Forsch | pmid:13765692 |
MALEK P and KOLC J | [Fluorescence method in the study of chlortetracycline penetration into the tissue]. | 1960 | Cas. Lek. Cesk. | pmid:13765752 |
MEYER-ROHN J | [Experimental and clinical trials with demethylchlortetracycline]. | 1960 | Arzneimittelforschung | pmid:13770045 |
MILOSEVIC M and TERZIC M | [Potentiation of the action of analgesics and hypnotics by chlortetracycline]. | 1960 | Therapie | pmid:13770986 |
TSINZERLING AV | [On the effect of chlortetracycline on the course of experimental candidamycosis in the lungs of white rats. II. Experiments with preliminary administration of chlortetracycline]. | 1960 | Biull Eksp Biol Med | pmid:13778374 |
VERGES G | [Identification and determination of tetracycline hydrochloride]. | 1960 | An Real Acad Farm | pmid:13780863 |
PARKS TR et al. | Thermal inactivation of chlortetracycline in various meat menstrua. | 1960 | Appl Microbiol | pmid:13732888 |
PETROV MN and MIRONOV GS | [Effect of biomycin on the clinical course of acute dysentery]. | 1960 | Sov Med | pmid:13734956 |
PRIGOT A et al. | The treatment of soft-tissue infections with demethylchlortetracycline. | 1960 | Antibiotic Med Clin Ther (New York) | pmid:13738020 |
REBER EF and NORTON HW | Studies of the effects of chlortetracycline, vitamin E, and vitamin K on the nutrition of the rat II. Reproduction. | 1960 | Am. J. Vet. Res. | pmid:13740111 |
FRIGERIO MJ | [A new tetracycline derivative: demethyl-chlortetracycline]. | 1960 | Dia Med | pmid:13825221 |
FUHRMAN DL and DROWNS BV | Demethylchlortetracycline. The clinical aspect of its use in dermatology. | 1960 | Arch Dermatol | pmid:13825561 |
KAWABATA T et al. | Factors affecting the decomposition of oxytetracycline and chlortetracycline. | 1960 | J. Antibiot. | pmid:13830905 |
SOBEK V | [Contribution to the influence of growth by chlortetracycline]. | 1960 | Cesk Fysiol | pmid:13832358 |
SOBEK V | [Effect of chlortetracycline on Clostridium perfringens toxin intoxication]. | 1960 | Cesk Fysiol | pmid:13832359 |
SWEENEY WM et al. | Antibiotic activity in urine and feces after oral and intravenous administration of demethylchlertetracycline. | 1960 | N. Engl. J. Med. | pmid:13836078 |
TRAFTON HM and LIND HE | Demethylchlortetracycline: effectiveness and tolerance in urinary tract infections. | 1960 | Antibiot Chemother | pmid:13839143 |
TUNEVALL G and FRISK AR | Bacteriological and clinical evaluation of demethylchlortetracycline. | 1960 | Antibiotic Med Clin Ther (New York) | pmid:13839825 |
TUNEVALL G and FRISK AR | [Demethylchlortetracycline]. | 1960 | Nord Med | pmid:13839826 |
VAUGHN RH et al. | Antibiotics in poultry meat preservation. Development in vitro of bacterial resistance to chlortetracycline. | 1960 | Appl Microbiol | pmid:13841490 |
VAVRECKA M et al. | [Effect of chlortetracycline on fat metabolism]. | 1960 | Cesk Fysiol | pmid:13841503 |
DOBREV D | [A case of biomycin hypersensitivity]. | 1960 | Suvr Med (Sofiia) | pmid:13723262 |
DOUJAK PH et al. | [Clinical and experimental research with aureomycin V]. | 1960 | Wien. Klin. Wochenschr. | pmid:13724077 |
FURESZ S et al. | [Blood levels of demethylchlortetracycline and tetracycline following administration of a single dose]. | 1960 | Minerva Med. | pmid:13702646 |
FINLAND M and GARROD LP | Demethylchlortetracycline. | 1960 | Br Med J | pmid:13822921 |
FRAGA FILHO C et al. | [Clinical and experimental investigations on a new compound of tetracycline: demethylchlortetracycline]. | 1960 | Hospital (Rio J) | pmid:13824296 |
MA ST | [Observations on 102 cases of pneumonia in infants treated with biomycin]. | 1960 | Zhonghua Er Ke Za Zhi | pmid:14467689 |
KNOTHE H | Demethylchlortetracycline: laboratory and clinical studies. | 1960 | Antibiotic Med Clin Ther (New York) | pmid:14410199 |
KOHN CM et al. | Demethylchlortetracycline in respiratory allergy. | 1960 | Ann Allergy | pmid:14410560 |
KOLLAR J and JARAI M | Biochemical studies on Streptomyces aureofaciens. I. Studies on the chlorination mechanism. | 1960 | Acta Microbiol Acad Sci Hung | pmid:14410718 |
KOLLAR J and JARAI M | Microbiological determination of small amounts of chloride. | 1960 | Acta Microbiol Acad Sci Hung | pmid:14410719 |
KUCK NA and REDIN GS | Comparison of demethylchlortetracycline with tetracycline in the control of experimental infections in mice. | 1960 | J. Pharmacol. Exp. Ther. | pmid:14412455 |
LARSON NL and HILL EG | Amine formation and metabolic activity of microorganisms in the ileum of young swine fed chlortetracycline. | 1960 | J. Bacteriol. | pmid:14414293 |
LI K | [The effect of chemotherapy on immunogenesis in experimental typhoid fever and dysentery infection. Part I. The effect of antibiotics on immunogenesis in experimental typhoid fever infection]. | 1960 | Zh. Mikrobiol. Epidemiol. Immunobiol. | pmid:14416635 |
LICHTER EA et al. | Demethylchlortetracycline therapy in pneumonia, scarlet fever, and other infections. | 1960 | Arch. Intern. Med. | pmid:14416754 |
LICHTER EA and SOBEL S | The distribution of oral demethylchlortetracycline in healthy volunteers and in patients under treatment for various infections. | 1960 | Antibiotic Med Clin Ther (New York) | pmid:14416755 |
LINZENMEIER G | [The sensitivity disc test with demethylchlortetracycline (DMCT)]. | 1960 | Chemotherapia (Basel) | pmid:14417352 |
MAGER J | Chloramphenicol and chlortetracycline inhibition of amino acid incorporation into proteins in a cell-free system from Tetrahymena pyriformis. | 1960 | Biochim. Biophys. Acta | pmid:14419796 |
MALEK P and KOLC J | Penetration of chlortetracycline into tissue affected by pathological changes. | 1960 | Antibiot Chemother (Northfield) | pmid:14420271 |
MOORE RW and WATKINS JR | The comparative effects of chlortetracycline and oxytetracycline in the treatment of turkeys with ornithosis. | 1960 | J. Am. Vet. Med. Assoc. | pmid:14423901 |
NEMIROVSKAIA BM | [Studies on the effect of chlortetracycline in combination with whooping cough vaccine on experimental whooping cough infection]. | 1960 | Zh. Mikrobiol. Epidemiol. Immunobiol. | pmid:14426528 |
RECHNIEWSKI C et al. | Preliminary report on the use of demethylchlortetracycline in infections of the urinary tract. | 1960 | Antibiotic Med Clin Ther (New York) | pmid:14436771 |
SALGARELLO G | [Research on drug protein binding. II. Electrophoretic data on the reactions of chlortetracycline with the water-soluble proteins of Escherichia coli K 12]. | 1960 | Boll. Soc. Ital. Biol. Sper. | pmid:14440989 |
SAZ AK and MARTINEZ LM | Enzymiatic basis of resistance to aureomycin. III. Inhibition by aureomycin of protein-stimulated electron transport in Eschericia coli. | 1960 | J. Bacteriol. | pmid:14442155 |
SCHOOG M | [An analysis of the effect of 7-chloro-6-demethyltetracycline]. | 1960 | Arzneimittelforschung | pmid:14443464 |
IYER R and IYER V | Action of chlortetracycline on Micrococcus pyogenes var. aureus in nutrient and non-nutrient media. | 1960 | Antibiot Chemother (Northfield) | pmid:14406186 |
IYER R and IYER V | Effect of agar on the inhibition of Micrococcus pyogenes var. aureus by chlortetracycline and other antibiotics. | 1960 | Antibiot Chemother (Northfield) | pmid:14406187 |
JAY JM | Studies on the development of chlortetracycline-resistant staphylococci in chlortetracyclin-treated beef. | 1960 | Antibiot Chemother (Northfield) | pmid:14406931 |
KIENITZ M | [Clinical and experiemntal research on the use of demethylchlortetracycline in pediatrics]. | 1960 | Med Lav | pmid:15445356 |
BUYSKE DA et al. | Concentration and persistence of tetracycline and chlortetracycline in bone. | 1960 | J. Pharmacol. Exp. Ther. | pmid:13689513 |