chlortetracycline is a lipid of Polyketides (PK) class. Chlortetracycline is associated with abnormalities such as Granulomatous Disease, Chronic, Infection, Ischemia, Cerebral Ischemia and Cerebral Infarction. The involved functions are known as Regulation, Binding (Molecular Function), Agent, Stimulus and Process. Chlortetracycline often locates in Protoplasm, Plasma membrane, Membrane, Cytoplasm and specific granule. The associated genes with chlortetracycline are FPR1 gene, P4HTM gene, Homologous Gene, HIST1H1C gene and Microbiome. The related lipids are Lysophosphatidylcholines, Sterols, dilauroyl lecithin, seminolipid and Total cholesterol. The related experimental models are Mouse Model.
To understand associated biological information of chlortetracycline, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
chlortetracycline is suspected in Ischemia, Cerebral Ischemia, Cerebral Infarction, Granulomatous Disease, Chronic, Infection, Antibiotic resistant infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with chlortetracycline
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'Chlortetracycline and demeclocycline inhibit calpains and protect mouse neurons against glutamate toxicity and cerebral ischemia.' (Jiang SX et al., 2005).
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Authors | Title | Published | Journal | PubMed Link |
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Chi Z and Liu R | New insights into the characterization of the binding of tetracycline analogues with lysozyme: a biophysical study. | 2012 | Chemosphere | pmid:22014467 |
Gao YY et al. | Treatment of ocular itching associated with ocular demodicosis by 5% tea tree oil ointment. | 2012 | Cornea | pmid:21955627 |
Pérez Aguirreburualde MS et al. | Acrosin activity regulation by protein kinase C and tyrosine kinase in bovine sperm acrosome exocytosis induced by lysophosphatidylcholine. | 2012 | Reprod. Domest. Anim. | pmid:22335484 |
Varel VH et al. | Effect of anaerobic digestion temperature on odour, coliforms and chlortetracycline in swine manure or monensin in cattle manure. | 2012 | J. Appl. Microbiol. | pmid:22313722 |
Guo RX and Chen JQ | Phytoplankton toxicity of the antibiotic chlortetracycline and its UV light degradation products. | 2012 | Chemosphere | pmid:22341398 |
Selvam A et al. | Composting of swine manure spiked with sulfadiazine, chlortetracycline and ciprofloxacin. | 2012 | Bioresour. Technol. | pmid:22261658 |
Lin X et al. | Differential regulation of OmpC and OmpF by AtpB in Escherichia coli exposed to nalidixic acid and chlortetracycline. | 2012 | J Proteomics | pmid:22960566 |
Liu F et al. | Changes in functional diversity of soil microbial community with addition of antibiotics sulfamethoxazole and chlortetracycline. | 2012 | Appl. Microbiol. Biotechnol. | pmid:22205443 |
Shelver WL and Varel VH | Development of a UHPLC-MS/MS method for the measurement of chlortetracycline degradation in swine manure. | 2012 | Anal Bioanal Chem | pmid:22207281 |
Poole TL et al. | Competitive effect of commensal faecal bacteria from growing swine fed chlortetracycline-supplemented feed on β-haemolytic Escherichia coli strains with multiple antimicrobial resistance plasmids. | 2012 | J. Appl. Microbiol. | pmid:22716900 |
Wang YX et al. | [Synthesis of core/shell structured magnetic carbon nanoparticles and its adsorption ability to chlortetracycline in aquatic environment]. | 2012 | Huan Jing Ke Xue | pmid:22720571 |
Li Z et al. | Determination on the binding of chlortetracycline to bovine serum albumin using spectroscopic methods. | 2012 | J. Biochem. Mol. Toxicol. | pmid:22730061 |
Kim TH et al. | Degradation and toxicity assessment of sulfamethoxazole and chlortetracycline using electron beam, ozone and UV. | 2012 | J. Hazard. Mater. | pmid:22682797 |
Wang LQ et al. | A molecularly imprinted photonic polymer sensor with high selectivity for tetracyclines analysis in food. | 2012 | Analyst | pmid:22705906 |
Hager D et al. | Stereoselective total syntheses of herbicidin C and aureonuclemycin through late-stage glycosylation. | 2012 | Angew. Chem. Int. Ed. Engl. | pmid:22644891 |
Dong L et al. | DNA damage and biochemical toxicity of antibiotics in soil on the earthworm Eisenia fetida. | 2012 | Chemosphere | pmid:22647195 |
Chen Y et al. | Photolysis of chlortetracycline in aqueous solution: kinetics, toxicity and products. | 2012 | J Environ Sci (China) | pmid:22655385 |
Lin D et al. | Physiological and molecular responses of the earthworm (Eisenia fetida) to soil chlortetracycline contamination. | 2012 | Environ. Pollut. | pmid:22868346 |
Liu X et al. | Potentials and mechanisms of genotoxicity of six pharmaceuticals frequently detected in freshwater environment. | 2012 | Toxicol. Lett. | pmid:22450446 |
Wen B et al. | Toxic effects of chlortetracycline on maize growth, reactive oxygen species generation and the antioxidant response. | 2012 | J Environ Sci (China) | pmid:23505878 |
Strait EL et al. | Dysgalactia associated with Mycoplasma suis infection in a sow herd. | 2012 | J. Am. Vet. Med. Assoc. | pmid:23216044 |
Levesque CL et al. | Ileal mucosa-associated--but not ileal digesta--bacterial profiles in grower pigs are influenced by nutrition and use of antibiotics for weaner pigs. | 2012 | J. Anim. Sci. | pmid:23365406 |
Dai M et al. | In vitro development and transfer of resistance to chlortetracycline in Bacillus subtilis. | 2012 | J. Microbiol. | pmid:23124749 |
Dreher TM et al. | Effects of chlortetracycline amended feed on anaerobic sequencing batch reactor performance of swine manure digestion. | 2012 | Bioresour. Technol. | pmid:23023238 |
Wang P et al. | Heterologous expression and manipulation of three tetracycline biosynthetic pathways. | 2012 | Angew. Chem. Int. Ed. Engl. | pmid:23024027 |
Kadirvel G et al. | Effect of cryopreservation on apoptotic-like events and its relationship with cryocapacitation of buffalo (Bubalus bubalis) sperm. | 2012 | Reprod. Domest. Anim. | pmid:21676035 |
Zhang C et al. | Validation of Polo-like kinase 1 as a therapeutic target in pancreatic cancer cells. | 2012 | Cancer Biol. Ther. | pmid:22892842 |
Wang X et al. | Dietary supplementation with the probiotic Lactobacillus fermentum I5007 and the antibiotic aureomycin differentially affects the small intestinal proteomes of weanling piglets. | 2012 | J. Nutr. | pmid:22113866 |
Daghrir R et al. | Photoelectrocatalytic degradation of chlortetracycline using Ti/TiO2 nanostructured electrodes deposited by means of a Pulsed Laser Deposition process. | 2012 | J. Hazard. Mater. | pmid:22104083 |
Pakpour S et al. | Frequency of antibiotic resistance in a swine facility 2.5 years after a ban on antibiotics. | 2012 | Microb. Ecol. | pmid:21997543 |
Apley MD et al. | Use estimates of in-feed antimicrobials in swine production in the United States. | 2012 | Foodborne Pathog. Dis. | pmid:22324295 |
Bachmann S et al. | Replacement of calcium for strontium in hamster sperm incubation media: effect on sperm function. | 2012 | Mol. Hum. Reprod. | pmid:21933847 |
Kim HY et al. | Biochemical effects of veterinary antibiotics on proliferation and cell cycle arrest of human HEK293 cells. | 2012 | Bull Environ Contam Toxicol | pmid:22673765 |
Kim KR et al. | Decline in extractable antibiotics in manure-based composts during composting. | 2012 | Waste Manag | pmid:21865024 |
Chi Z et al. | Binding of tetracycline and chlortetracycline to the enzyme trypsin: spectroscopic and molecular modeling investigations. | 2011 | PLoS ONE | pmid:22205948 |
Nelson ML and Levy SB | The history of the tetracyclines. | 2011 | Ann. N. Y. Acad. Sci. | pmid:22191524 |
Duggar BM | Aureomycin: a product of the continuing search for new antibiotics. | 2011 | Ann. N. Y. Acad. Sci. | pmid:22191532 |
Zhang D et al. | Strong adsorption of chlorotetracycline on magnetite nanoparticles. | 2011 | J. Hazard. Mater. | pmid:21724321 |
Stone JJ et al. | Impact of chlortetracycline on sequencing batch reactor performance for swine manure treatment. | 2011 | Bioresour. Technol. | pmid:21724384 |
Guillot M et al. | In growing pigs, chlortetracycline induces a reversible green bone discoloration and a persistent increase of bone mineral density dependent of dosing regimen. | 2011 | Res. Vet. Sci. | pmid:20723952 |
Kato Y et al. | Capacitation status of activated bovine sperm cultured in media containing methyl-β-cyclodextrin affects the acrosome reaction and fertility. | 2011 | Zygote | pmid:20727245 |
Wu RB et al. | Prevalence and diversity of class 1 integrons and resistance genes in antimicrobial-resistant Escherichia coli originating from beef cattle administered subtherapeutic antimicrobials. | 2011 | J. Appl. Microbiol. | pmid:21645183 |
Volkers G et al. | Recognition of drug degradation products by target proteins: isotetracycline binding to Tet repressor. | 2011 | J. Med. Chem. | pmid:21699184 |
Bernabò N et al. | The role of actin in capacitation-related signaling: an in silico and in vitro study. | 2011 | BMC Syst Biol | pmid:21450097 |
Miah AG et al. | Intracellular signaling cascades induced by relaxin in the stimulation of capacitation and acrosome reaction in fresh and frozen-thawed bovine spermatozoa. | 2011 | Anim. Reprod. Sci. | pmid:21493019 |
Dong XF et al. | Effects of dietary polysavone (Alfalfa extract) and chlortetracycline supplementation on antioxidation and meat quality in broiler chickens. | 2011 | Br. Poult. Sci. | pmid:21732875 |
Alexander TW et al. | Longitudinal characterization of antimicrobial resistance genes in feces shed from cattle fed different subtherapeutic antibiotics. | 2011 | BMC Microbiol. | pmid:21261985 |
Chander Y et al. | Identification of the tet(B) resistance gene in Streptococcus suis. | 2011 | Vet. J. | pmid:20696603 |
Griffin MO et al. | Tetracycline compounds with non-antimicrobial organ protective properties: possible mechanisms of action. | 2011 | Pharmacol. Res. | pmid:20951211 |
Stone JJ et al. | Land application of tylosin and chlortetracycline swine manure: Impacts to soil nutrients and soil microbial community structure. | 2011 | J Environ Sci Health B | pmid:21877979 |