chlortetracycline

chlortetracycline is a lipid of Polyketides (PK) class. Chlortetracycline is associated with abnormalities such as Granulomatous Disease, Chronic, Infection, Ischemia, Cerebral Ischemia and Cerebral Infarction. The involved functions are known as Regulation, Binding (Molecular Function), Agent, Stimulus and Process. Chlortetracycline often locates in Protoplasm, Plasma membrane, Membrane, Cytoplasm and specific granule. The associated genes with chlortetracycline are FPR1 gene, P4HTM gene, Homologous Gene, HIST1H1C gene and Microbiome. The related lipids are Lysophosphatidylcholines, Sterols, dilauroyl lecithin, seminolipid and Total cholesterol. The related experimental models are Mouse Model.

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Introduction

To understand associated biological information of chlortetracycline, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with chlortetracycline?

chlortetracycline is suspected in Ischemia, Cerebral Ischemia, Cerebral Infarction, Granulomatous Disease, Chronic, Infection, Antibiotic resistant infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with chlortetracycline

MeSH term MeSH ID Detail
Poultry Diseases D011201 21 associated lipids
Bacterial Infections D001424 21 associated lipids
Escherichia coli Infections D004927 17 associated lipids
Swine Diseases D013553 16 associated lipids
Staphylococcal Infections D013203 15 associated lipids
Synovitis D013585 15 associated lipids
Campylobacter Infections D002169 13 associated lipids
Mycoplasma Infections D009175 13 associated lipids
Corneal Diseases D003316 13 associated lipids
Otitis Media D010033 12 associated lipids
Per page 10 20 50 | Total 49

PubChem Associated disorders and diseases

What pathways are associated with chlortetracycline

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with chlortetracycline?

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What functions are associated with chlortetracycline?


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What lipids are associated with chlortetracycline?

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What genes are associated with chlortetracycline?

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What common seen animal models are associated with chlortetracycline?

Mouse Model

Mouse Model are used in the study 'Chlortetracycline and demeclocycline inhibit calpains and protect mouse neurons against glutamate toxicity and cerebral ischemia.' (Jiang SX et al., 2005).

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NCBI Entrez Crosslinks

All references with chlortetracycline

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Authors Title Published Journal PubMed Link
Malíková M and Matyás Z [Chlortetracycline residues in the meat of slaughter calves in relation to transmissible microbial resistance to antibiotics]. 1980 Vet Med (Praha) pmid:6777944
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Takeshige K et al. Release of calcium from membranes and its relation to phagocytotic metabolic changes: a fluorescence study on leukocytes loaded with chlortetracycline. 1980 Biochem. Biophys. Res. Commun. pmid:6251808
Wolniak SM et al. Detection of the membrane-calcium distribution during mitosis in Haemanthus endosperm with chlorotetracycline. 1980 J. Cell Biol. pmid:7419592
Ragheb HS Some factors affecting assay variability in the determination of chlortetracycline in premix feeds. 1980 J Assoc Off Anal Chem pmid:7430030
Uchida M Histamine-induced decrease of membrane-bound calcium ions in the membrane fraction of rabbit taenia coli. 1980 Eur. J. Pharmacol. pmid:7389828
Clark LK Coccidiosis in baby pigs. 1980 Mod Vet Pract pmid:7432341
Gains N The limitations of chlorotetracycline as a fluorescent probe of divalent cations associated with membranes. 1980 Eur. J. Biochem. pmid:7439184
Rummer HJ and Elze K [Control of puerperium in swine under conditions of extremely shortened nursing method. 1. Results of histological studies in postpartum involution and regeneration of the uterus under conditions of extremely shortened nursing period and medicamentous control of puerperium]. 1980 Arch Exp Veterinarmed pmid:7447598
Gawlitta W et al. Pinocytosis and locomotion of amoebae. XV. Visualization of Ca++-dynamics by chlorotetracycline (CTC) fluorescence during induced pinocytosis in living Amoeba proteus. 1980 Cell Tissue Res. pmid:7459998
Nagasaki K and Kasai M Magnesium permeability of sarcoplasmic reticulum vesicles monitored in terms of chlortetracycline fluorescence. 1980 J. Biochem. pmid:7390959
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Feinstein MB Release of intracellular membrane-bound calcium precedes the onset of stimulus-induced exocytosis in platelets. 1980 Biochem. Biophys. Res. Commun. pmid:6992773
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Remillard RL et al. Subtherapeutic tetracycline effects on recovery patterns of calves after Salmonella typhimurium challenge. 1981 J. Dairy Sci. pmid:7021619
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Waldroup PW et al. Comparison of low dietary calcium and sodium sulfate for the potentiation of tetracycline antibiotics in broiler diets. 1981 Oct-Dec Avian Dis. pmid:7337611
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Gimble JM et al. Studies on the Ca2+ transport mechanism of human erythrocyte inside-out plasma membrane vesicles. V. Chlortetracycline fluorescence. 1982 Biochim. Biophys. Acta pmid:6802179
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Anifantakis EM Excretion rates of antibiotics in milk of sheep and their effect on yogurt production. 1982 J. Dairy Sci. pmid:6176606
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Pershadsingh HA et al. Ca2+-dependent depolarization of energized mitochondrial membrane potential by chlortetracycline (aureomycin). 1982 J. Biol. Chem. pmid:6182140
Best L et al. Phosphoinositide metabolism in human blood platelets: effects of two types of divalent cation chelators. 1982 Thromb. Res. pmid:6287663
Jechová V et al. Role of phosphatases in the biosynthesis of chlortetracycline in Streptomyces aureofaciens. 1982 Folia Microbiol. (Praha) pmid:6125456
Mathew MK et al. Ionophore-mediated transmembrane movement of divalent cations in small unilamellar liposomes: an evaluation of the chlortetracycline fluorescence technique and correlations with black lipid membrane studies. 1982 J. Membr. Biol. pmid:7057457
Skakun NP and VysotskiÄ­ IIu [Effect of tetracyclines on bile formation in the liver]. 1982 Antibiotiki pmid:7092192
Riquelme G et al. Lipid monolayer expansion by calcium-chlorotetracycline at the air/water interface and, as inferred from cell shape changes, in the human erythrocyte membrane. 1982 Biochim. Biophys. Acta pmid:7115708
Smolen JE et al. The fluorescence response of chlorotetracycline-loaded human neutrophils. Correlations with lysosomal enzyme release and evidence for a 'trigger pool' of calcium. 1982 Biochim. Biophys. Acta pmid:7126637
Chiang T Inhibition of chlortetracycline activity by magnesium ions. 1982 J Assoc Off Anal Chem pmid:7130073
Yokoyama MT et al. The effects of antibiotics in the weanling pig diet on growth and the excretion of volatile phenolic and aromatic bacterial metabolites. 1982 Am. J. Clin. Nutr. pmid:7081123
Gatsonis CD and Ageloudis CA Quantitative determination of antibiotics by means of densitometry on TLC. Part 2: Determination of tetracyclines. 1982 Pharmazie pmid:7146072
Obara K and Yabu H Effects of caffeine on contraction and chlorotetracycline fluorescence in isolated single smooth muscle cells of guinea pig taenia coli. 1982 Jpn. J. Physiol. pmid:7169694
Bradley BD et al. Comparative pharmacokinetics of chlortetracycline in milk-fed versus conventionally fed calves. 1982 J. Vet. Pharmacol. Ther. pmid:7183795
Krishnan H et al. Effect of temperature acclimatisation of cockroaches on the binding of Ca2+ & Mg2+ to the coxal muscle mitochondria as visualised by fluorescent probe chlorotetracycline. 1982 Indian J. Biochem. Biophys. pmid:7184864
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Edelson HS et al. Dissociation by piroxicam of degranulation and superoxide anion generation from decrements in chlortetracycline fluorescence of activated human neutrophils. 1982 Biochem. Biophys. Res. Commun. pmid:6280690
Smolen JE and Weissmann G The effect of various stimuli and calcium antagonists on the fluorescence response of chlorotetracycline-loaded human neutrophils. 1982 Biochim. Biophys. Acta pmid:6282339
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Gershengorn MC and Thaw C TRH mobilizes membrane calcium in thyrotropic cells as monitored by chlortetracycline. 1982 Am. J. Physiol. pmid:6812433
NaÄ­denova M and Valerianov Ts [Isolation and characterization of mutants with blocked chlortetracycline biosynthesis]. 1982 Acta Microbiol Bulg pmid:6816018
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Schneider AS et al. Chlortetracycline as a probe of membrane-associated calcium and magnesium: interaction with red cell membranes, phospholipids, and proteins monitored by fluorescence and circular dichroism. 1983 Biochemistry pmid:6849877
Burgess T and Chiang T Effect of citric acid on inhibition of chlortetracycline activity by magnesium ions. 1983 J Assoc Off Anal Chem pmid:6863179
White JR and Pearce FL Effect of anti-allergic and cyclic AMP-active drugs on histamine secretion from rat mast cells treated with the novel calcium ionophore chlortetracycline. 1983 Int. Arch. Allergy Appl. Immunol. pmid:6190762
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Coates TD et al. The mechanism of action of the antiinflammatory agents dexamethasone and Auranofin in human polymorphonuclear leukocytes. 1983 Blood pmid:6313097
Smolen JE The fluorescence response of chlortetracycline-loaded human neutrophils is modulated by prostaglandin E1, but not by cyclic nucleotides. 1983 FEBS Lett. pmid:6313429
Smolen JE et al. Metabolic requirements for maintenance of the chlortetracycline-labeled pool of membrane-bound calcium in human neutrophils. 1983 J. Cell. Physiol. pmid:6654990
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Moyed HS and Bertrand KP Mutations in multicopy Tn10 tet plasmids that confer resistance to inhibitory effects of inducers of tet gene expression. 1983 J. Bacteriol. pmid:6307969
White JR and Pearce FL Use of chlortetracycline to monitor calcium mobilization during histamine secretion from the mast cell: a cautionary note. 1983 Anal. Biochem. pmid:6625151
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Skakun NP and VysotskiÄ­ IIu [Vitamin E and selenium-containing preparations in the prevention treatment of tetracycline-induced lesions of the liver]. 1983 Antibiotiki pmid:6638974
Skakun NP and VysotskiÄ­ IIu [Content of SH- and --S--S-groups in the blood and liver homogenates in acute poisoning with tetracycline antibiotics]. 1983 Antibiotiki pmid:6638982
Dawson KA et al. Multiple antibiotic resistance in fecal, cecal and colonic coliforms from pigs fed therapeutic and subtherapeutic concentrations of chlortetracycline. 1983 J. Anim. Sci. pmid:6643317
Nagasaki K and Kasai M Fast release of calcium from sarcoplasmic reticulum vesicles monitored by chlortetracycline fluorescence. 1983 J. Biochem. pmid:6654845
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