chlortetracycline

chlortetracycline is a lipid of Polyketides (PK) class. Chlortetracycline is associated with abnormalities such as Granulomatous Disease, Chronic, Infection, Ischemia, Cerebral Ischemia and Cerebral Infarction. The involved functions are known as Regulation, Binding (Molecular Function), Agent, Stimulus and Process. Chlortetracycline often locates in Protoplasm, Plasma membrane, Membrane, Cytoplasm and specific granule. The associated genes with chlortetracycline are FPR1 gene, P4HTM gene, Homologous Gene, HIST1H1C gene and Microbiome. The related lipids are Lysophosphatidylcholines, Sterols, dilauroyl lecithin, seminolipid and Total cholesterol. The related experimental models are Mouse Model.

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Introduction

To understand associated biological information of chlortetracycline, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with chlortetracycline?

chlortetracycline is suspected in Ischemia, Cerebral Ischemia, Cerebral Infarction, Granulomatous Disease, Chronic, Infection, Antibiotic resistant infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with chlortetracycline

MeSH term MeSH ID Detail
Hyperglycemia D006943 21 associated lipids
Impetigo D007169 3 associated lipids
Inflammation D007249 119 associated lipids
Leukemia, Experimental D007942 42 associated lipids
Lymphadenitis D008199 8 associated lipids
Mycoplasma Infections D009175 13 associated lipids
Myocardial Infarction D009203 21 associated lipids
Osteomyelitis D010019 10 associated lipids
Otitis Media D010033 12 associated lipids
Pasteurella Infections D010326 8 associated lipids
Per page 10 20 50 | Total 49

PubChem Associated disorders and diseases

What pathways are associated with chlortetracycline

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with chlortetracycline?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with chlortetracycline?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with chlortetracycline?

Related references are published most in these journals:

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What genes are associated with chlortetracycline?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with chlortetracycline?

Mouse Model

Mouse Model are used in the study 'Chlortetracycline and demeclocycline inhibit calpains and protect mouse neurons against glutamate toxicity and cerebral ischemia.' (Jiang SX et al., 2005).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with chlortetracycline

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Per page 10 20 50 100 | Total 4669
Authors Title Published Journal PubMed Link
Smolen JE The fluorescence response of chlortetracycline-loaded human neutrophils is modulated by prostaglandin E1, but not by cyclic nucleotides. 1983 FEBS Lett. pmid:6313429
Coates TD et al. The mechanism of action of the antiinflammatory agents dexamethasone and Auranofin in human polymorphonuclear leukocytes. 1983 Blood pmid:6313097
Moyed HS and Bertrand KP Mutations in multicopy Tn10 tet plasmids that confer resistance to inhibitory effects of inducers of tet gene expression. 1983 J. Bacteriol. pmid:6307969
Priputina LS et al. [Information in support of barring the use of tetracyclines and streptomycin as growth stimulants]. 1982 May-Jun Vopr Pitan pmid:6287735
Best L et al. Phosphoinositide metabolism in human blood platelets: effects of two types of divalent cation chelators. 1982 Thromb. Res. pmid:6287663
Fabiato A Fluorescence and differential light absorption recordings with calcium probes and potential-sensitive dyes in skinned cardiac cells. 1982 Can. J. Physiol. Pharmacol. pmid:6286076
Takeshige K et al. Release of the membrane-calcium and its relation to the superoxide formation by polymorphonuclear leukocytes. 1982 Adv. Exp. Med. Biol. pmid:6283837
Smolen JE and Weissmann G The effect of various stimuli and calcium antagonists on the fluorescence response of chlorotetracycline-loaded human neutrophils. 1982 Biochim. Biophys. Acta pmid:6282339
Edelson HS et al. Dissociation by piroxicam of degranulation and superoxide anion generation from decrements in chlortetracycline fluorescence of activated human neutrophils. 1982 Biochem. Biophys. Res. Commun. pmid:6280690
Mathew MK et al. Membrane channel-forming polypeptides. Aqueous phase aggregation and membrane-modifying activity of synthetic fluorescent alamethicin fragments. 1982 J. Biol. Chem. pmid:6277888
Owen NE and Le Breton GC Ca2+ mobilization in blood platelets as visualized by chlortetracycline fluorescence. 1981 Am. J. Physiol. pmid:6274207
Takeshige K et al. Release of calcium from membranes and its relation to phagocytotic metabolic changes: a fluorescence study on leukocytes loaded with chlortetracycline. 1980 Biochem. Biophys. Res. Commun. pmid:6251808
West GB Histamine release from mast cells of the rat. 1984 Int. Arch. Allergy Appl. Immunol. pmid:6202644
Kim JV et al. Ca2+ transport in mitochondria of the ciliate protozoan Tetrahymena pyriformis. 1984 Cell Calcium pmid:6201283
Palevitz BA and Hodge LD The endoplasmic reticulum in the cortex of developing guard cells: coordinate studies with chlorotetracycline and osmium ferricyanide. 1984 Dev. Biol. pmid:6198223
Pearce FL et al. Histamine secretion from mast cells treated with chlortetracycline (aureomycin): a novel calcium ionophore. 1983 Agents Actions pmid:6191538
White JR and Pearce FL Effect of anti-allergic and cyclic AMP-active drugs on histamine secretion from rat mast cells treated with the novel calcium ionophore chlortetracycline. 1983 Int. Arch. Allergy Appl. Immunol. pmid:6190762
Streptococcal infections of skin and pharynx. 1978 N. Engl. J. Med. pmid:618456
Pershadsingh HA et al. Ca2+-dependent depolarization of energized mitochondrial membrane potential by chlortetracycline (aureomycin). 1982 J. Biol. Chem. pmid:6182140
Gershengorn MC Thyrotropin releasing hormone. A review of the mechanisms of acute stimulation of pituitary hormone release. 1982 Mol. Cell. Biochem. pmid:6181387