oxytetracycline

oxytetracycline is a lipid of Polyketides (PK) class. Oxytetracycline is associated with abnormalities such as Infection, X-linked centronuclear myopathy, Bacterial Infections, Heart failure and Onchocerciasis. The involved functions are known as Anabolism, physiological aspects, Transcription, Genetic, Fermentation and Transcriptional Activation. Oxytetracycline often locates in Chromosomes, Flank (surface region), Entire bony skeleton, Bone Marrow and Body tissue. The associated genes with oxytetracycline are Polypeptides, Homologous Gene, Gene Clusters, Locus and CYCS gene. The related lipids are LH 1 and Lipid Peroxides. The related experimental models are Disease model.

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Introduction

To understand associated biological information of oxytetracycline, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with oxytetracycline?

oxytetracycline is suspected in Infection, Helminthiasis, Nodule, Bacterial Infections, Yeast infection, pathologic fistula and other diseases in descending order of the highest number of associated sentences.

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Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with oxytetracycline

PubChem Associated disorders and diseases

What pathways are associated with oxytetracycline

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with oxytetracycline?

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What functions are associated with oxytetracycline?


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What lipids are associated with oxytetracycline?

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What genes are associated with oxytetracycline?

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What common seen animal models are associated with oxytetracycline?

Disease model

Disease model are used in the study 'A molecular ecological approach to the detection and designation of the etiological agents of a model polymicrobial disease.' (Antiabong JF et al., 2013).

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NCBI Entrez Crosslinks

All references with oxytetracycline

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Authors Title Published Journal PubMed Link
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Magonigle RA et al. Efficacy of a new oxytetracycline formulation against clinical anaplasmosis. 1978 Am. J. Vet. Res. pmid:697150
Wooley RE et al. Inhibitory effects of combinations of oxytetracycline, dimethyl sulfoxide, and EDTA-tromethamine on Escherichia coli. 1981 Am. J. Vet. Res. pmid:6802044
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Ames TR et al. Oxytetracycline concentrations in healthy and diseased calves. 1983 Am. J. Vet. Res. pmid:6881673
Kuttler KL and Simpson JE Relative efficacy of two oxytetracycline formulations and doxycycline in the treatment of acute anaplasmosis in splenectomized calves. 1978 Am. J. Vet. Res. pmid:629473
Clark JD et al. Effects of various treatments on induced chronic aflatoxicosis in rabbits. 1982 Am. J. Vet. Res. pmid:6807140
Wooley RE et al. Antibacterial action of combinations of oxytetracycline, dimethyl sulfoxide, and EDTA-tromethamine on Proteus, Salmonella, and Aeromonas. 1982 Am. J. Vet. Res. pmid:6807142
Latour PB and Barnum DA Use of ducks as a model to study the effect of antibiotics in feed on the fecal shedding of Salmonella. 1981 Am. J. Vet. Res. pmid:7041704
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Dyer DC Pharmacokinetics of oxytetracycline in the turkey: evaluation of biliary and urinary excretion. 1989 Am. J. Vet. Res. pmid:2712419
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Marín CM et al. Efficacy of long-acting oxytetracycline alone or in combination with streptomycin for treatment of Brucella ovis infection of rams. 1989 Am. J. Vet. Res. pmid:2712423
Wooley RE et al. Attempted reversal of oxytetracycline resistance of Proteus mirabilis by EDTA-tromethamine lavage in experimentally induced canine and feline cystitis. 1975 Am. J. Vet. Res. pmid:811139
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Kuttler KL Influence of a second Anaplasma exposure on the success of treatment to eliminate Anaplasma carrier infections in cattle. 1983 Am. J. Vet. Res. pmid:6869997
George LW et al. Comparison of two oxytetracycline formulations in the treatment of laboratory-induced pasteurellosis of pigs. 1983 Am. J. Vet. Res. pmid:6870001
Bowen JM and McMullan WC Influence of induced hypermagnesemia and hypocalcemia on neuromuscular blocking property of oxytetracycline in the horse. 1975 Am. J. Vet. Res. pmid:1147343
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Kerwin SC et al. Effect of hyperbaric oxygen treatment on incorporation of an autogenous cancellous bone graft in a nonunion diaphyseal ulnar defect in cats. 2000 Am. J. Vet. Res. pmid:10850847
Ferré PJ et al. Comparison of ultrasonography and pharmacokinetic analysis of creatine kinase release for quantitative assessment of postinjection muscle damage in sheep. 2001 Am. J. Vet. Res. pmid:11703010
Wooley RE et al. In vitro action of combinations of antimicrobial agents and EDTA-tromethamine on Pseudomonas aeruginosa. 1983 Am. J. Vet. Res. pmid:6414345
Kaneene JB et al. Drug residues in milk after intrauterine injection of oxytetracycline, lincomycin-spectinomycin, and povidone-iodine in cows with metritis. 1986 Am. J. Vet. Res. pmid:2942064
MacNeil JD et al. Bioassay techniques and high-performance liquid chromatography for detection of oxytetracycline residues in tissues from calves. 1989 Am. J. Vet. Res. pmid:2919831
Pindak FF et al. Incidence and distribution of spirochetes in the digestive tract of dogs. 1965 Am. J. Vet. Res. pmid:5882556
Lubbers BV et al. Effects of two simulated oxytetracycline dosing regimens on horizontal transfer of antimicrobial resistance plasmids in an in vitro pharmacodynamic model. 2011 Am. J. Vet. Res. pmid:21728847
Palmer JE et al. Effect of treatment with oxytetracycline during the acute stages of experimentally induced equine ehrlichial colitis in ponies. 1992 Am. J. Vet. Res. pmid:1476312
Oukessou M et al. Pharmacokinetics and local tolerance of a long-acting oxytetracycline formulation in camels. 1992 Am. J. Vet. Res. pmid:1416372
Gross DR et al. Adverse cardiovascular effects of oxytetracycline preparations and vehicles in intact awake calves. 1981 Am. J. Vet. Res. pmid:7294473
Gyles C et al. In vivo transfer of an Escherichia coli enterotoxin plasmid possessing genes for drug resistance. 1978 Am. J. Vet. Res. pmid:358869
byford RL et al. Chemoprophylaxis of vector-borne anaplasmosis with sustained-release boluses. 1981 Am. J. Vet. Res. pmid:7340579
McElroy DE et al. Pharmacokinetics of oxytetracycline hydrochloride in rabbits. 1987 Am. J. Vet. Res. pmid:3631718
Larson VL and Stowe CM Plasma and tissue concentrations of oxytetracycline in the horse after intravenous administration. 1981 Am. J. Vet. Res. pmid:7340586
Hidalgo RJ Propagation of Anaplasma marginale in bovine lymph node cell culture. 1975 Am. J. Vet. Res. pmid:1094867
Fugler LA et al. Plasma matrix metalloproteinase activity in horses after intravenous infusion of lipopolysaccharide and treatment with matrix metalloproteinase inhibitors. 2013 Am. J. Vet. Res. pmid:23438126
Fielding CL et al. Evaluation of potential predictor variables for PCR assay diagnosis of Anaplasma phagocytophilum infection in equids in Northern California. 2018 Am. J. Vet. Res. pmid:30085857
Edmondson AJ et al. Survival analysis for evaluation of corneal ulcer healing times in calves with naturally acquired infectious bovine keratoconjunctivitis. 1989 Am. J. Vet. Res. pmid:2764337
Ames TR and Patterson EB Oxytetracycline concentrations in plasma and lung of healthy and pneumonic calves, using two oxytetracycline preparations. 1985 Am. J. Vet. Res. pmid:3909863
Button C and Mülders MS Effects of oxytetracycline in propylene glycol, oxytetracycline in saline solution, and propylene glycol alone on blood ionized calcium and plasma total calcium in sheep. 1984 Am. J. Vet. Res. pmid:6476580
Paulsen DB et al. Use of an indwelling bronchial catheter model of bovine pneumonic pasteurellosis for evaluation of therapeutic efficacy of various compounds. 1992 Am. J. Vet. Res. pmid:1524292
Tornquist SJ et al. Use of a polymerase chain reaction assay to study response to oxytetracycline treatment in experimental Candidatus Mycoplasma haemolamae infection in alpacas. 2009 Am. J. Vet. Res. pmid:19719425
Smith JA and George LW Treatment of acute ocular Moraxella bovis infections in calves with a parenterally administered long-acting oxytetracycline formulation. 1985 Am. J. Vet. Res. pmid:4014830