oxytetracycline is a lipid of Polyketides (PK) class. Oxytetracycline is associated with abnormalities such as Infection, X-linked centronuclear myopathy, Bacterial Infections, Heart failure and Onchocerciasis. The involved functions are known as Anabolism, physiological aspects, Transcription, Genetic, Fermentation and Transcriptional Activation. Oxytetracycline often locates in Chromosomes, Flank (surface region), Entire bony skeleton, Bone Marrow and Body tissue. The associated genes with oxytetracycline are Polypeptides, Homologous Gene, Gene Clusters, Locus and CYCS gene. The related lipids are LH 1 and Lipid Peroxides. The related experimental models are Disease model.
To understand associated biological information of oxytetracycline, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
oxytetracycline is suspected in Infection, Helminthiasis, Nodule, Bacterial Infections, Yeast infection, pathologic fistula and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with oxytetracycline
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Disease model are used in the study 'A molecular ecological approach to the detection and designation of the etiological agents of a model polymicrobial disease.' (Antiabong JF et al., 2013).
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Authors | Title | Published | Journal | PubMed Link |
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Teare JA et al. | Pharmacokinetics of a long-acting oxytetracycline preparation in ring-necked pheasants, great horned owls, and Amazon parrots. | 1985 | Am. J. Vet. Res. | pmid:4083606 |
Palmer GH et al. | Absorption in calves of amoxicillin, ampicillin, and oxytetracycline given in milk replacer, water, or an oral rehydration formulation. | 1983 | Am. J. Vet. Res. | pmid:6824227 |
Wooley RE et al. | Inhibitory effects of combinations of oxytetracycline, dimethyl sulfoxide, and EDTA-tromethamine on Escherichia coli. | 1981 | Am. J. Vet. Res. | pmid:6802044 |
Hatch RC et al. | Induced acute aflatoxicosis in goats: treatment with activated charcoal or dual combinations of oxytetracycline, stanozolol, and activated charcoal. | 1982 | Am. J. Vet. Res. | pmid:6803625 |
Toutain PL and Raynaud JP | Pharmacokinetics of oxytetracycline in young cattle: comparison of conventional vs long-acting formulations. | 1983 | Am. J. Vet. Res. | pmid:6881660 |
Ames TR et al. | Oxytetracycline concentrations in healthy and diseased calves. | 1983 | Am. J. Vet. Res. | pmid:6881673 |
Kuttler KL and Simpson JE | Relative efficacy of two oxytetracycline formulations and doxycycline in the treatment of acute anaplasmosis in splenectomized calves. | 1978 | Am. J. Vet. Res. | pmid:629473 |
Clark JD et al. | Effects of various treatments on induced chronic aflatoxicosis in rabbits. | 1982 | Am. J. Vet. Res. | pmid:6807140 |
Wooley RE et al. | Antibacterial action of combinations of oxytetracycline, dimethyl sulfoxide, and EDTA-tromethamine on Proteus, Salmonella, and Aeromonas. | 1982 | Am. J. Vet. Res. | pmid:6807142 |
Latour PB and Barnum DA | Use of ducks as a model to study the effect of antibiotics in feed on the fecal shedding of Salmonella. | 1981 | Am. J. Vet. Res. | pmid:7041704 |
George LW et al. | Effectiveness of two benzathine cloxacillin formulations for treatment of naturally occurring infectious bovine keratoconjunctivitis. | 1989 | Am. J. Vet. Res. | pmid:2774340 |
DOZSA L and OLSON NO | THE EFFECT OF VARIOUS ANTIBIOTICS ON THE UTERINE MUCOSA OF VIBRIO FETUS-INFECTED COWS. | 1964 | Am. J. Vet. Res. | pmid:14103211 |
Kniffen TS et al. | Bioavailability, pharmacokinetics, and plasma concentration of tetracycline hydrochloride fed to swine. | 1989 | Am. J. Vet. Res. | pmid:2712418 |
Rohde C et al. | Effects of phenylbutazone on bone activity and formation in horses. | 2000 | Am. J. Vet. Res. | pmid:10803649 |
Kuttler KL | Influence of a second Anaplasma exposure on the success of treatment to eliminate Anaplasma carrier infections in cattle. | 1983 | Am. J. Vet. Res. | pmid:6869997 |
VanEnkevort BA et al. | Alterations in bone remodeling in the femur after medullary reaming and cemented hip arthroplasty in dogs. | 1999 | Am. J. Vet. Res. | pmid:10451197 |
George LW et al. | Comparison of two oxytetracycline formulations in the treatment of laboratory-induced pasteurellosis of pigs. | 1983 | Am. J. Vet. Res. | pmid:6870001 |
Bowen JM and McMullan WC | Influence of induced hypermagnesemia and hypocalcemia on neuromuscular blocking property of oxytetracycline in the horse. | 1975 | Am. J. Vet. Res. | pmid:1147343 |
Davis RW et al. | The effects of an oxytetracycline preparation on the thyroid gland: a preliminary report. | 1966 | Am. J. Vet. Res. | pmid:5913021 |
Owen RA et al. | Effects of transportation, surgery, and antibiotic therapy in ponies infected with Salmonella. | 1983 | Am. J. Vet. Res. | pmid:6337537 |
Kerwin SC et al. | Effect of hyperbaric oxygen treatment on incorporation of an autogenous cancellous bone graft in a nonunion diaphyseal ulnar defect in cats. | 2000 | Am. J. Vet. Res. | pmid:10850847 |
Ferré PJ et al. | Comparison of ultrasonography and pharmacokinetic analysis of creatine kinase release for quantitative assessment of postinjection muscle damage in sheep. | 2001 | Am. J. Vet. Res. | pmid:11703010 |
Simpson CF | Morphologic alterations of Anaplasma marginale in calves after treatment with oxytetracycline. | 1975 | Am. J. Vet. Res. | pmid:1190584 |
Brown MP and MacCallum FJ | A system of grading ossification in limbs of foals to assist in radiologic interpretation. | 1975 | Am. J. Vet. Res. | pmid:1137212 |
BARNES LE | Oxytetracycline in bovine mastitis. I. Treatment of mastitis. | 1955 | Am. J. Vet. Res. | pmid:13238740 |
Pindak FF et al. | Incidence and distribution of spirochetes in the digestive tract of dogs. | 1965 | Am. J. Vet. Res. | pmid:5882556 |
Guerra MA and Nicoletti P | Comparison of the susceptibility of Brucella abortus isolates obtained before and after cows were treated with oxytetracycline and streptomycin. | 1986 | Am. J. Vet. Res. | pmid:3099613 |
Bretzlaff KN et al. | Distribution of oxytetracycline in the genital tract of cows. | 1982 | Am. J. Vet. Res. | pmid:7091807 |
Lubbers BV et al. | Effects of two simulated oxytetracycline dosing regimens on horizontal transfer of antimicrobial resistance plasmids in an in vitro pharmacodynamic model. | 2011 | Am. J. Vet. Res. | pmid:21728847 |
Sarmiento JI and Moon HW | Postweaning diarrhea in swine: effects of oxytetracycline on enterotoxigenic Escherichia coli infection. | 1988 | Am. J. Vet. Res. | pmid:3048158 |
Magonigle RA and Newby TJ | Elimination of naturally acquired chronic Anaplasma marginale infections with a long-acting oxytetracycline injectable. | 1982 | Am. J. Vet. Res. | pmid:7165161 |
Kuttler KL | Efficacy of oxytetracycline and a dithiosemicarbazone in the treatment of bovine anaplasmosis. | 1971 | Am. J. Vet. Res. | pmid:5094519 |
Hatch RC et al. | Effect of antibacterials, anabolic steroid, and diethyldithiocarbamate on induced acute aflatoxicosis in goats. | 1982 | Am. J. Vet. Res. | pmid:6280533 |
Gross DR et al. | Cardiovascular effects of intravenous administration of propylene glycol and of oxytetracycline in propylene glycol in calves. | 1979 | Am. J. Vet. Res. | pmid:475130 |
Gross DR et al. | Adverse cardiovascular effects of oxytetracycline preparations and vehicles in intact awake calves. | 1981 | Am. J. Vet. Res. | pmid:7294473 |
Abbitt B et al. | Effect of dihydrostreptomycin or oxytetracycline on reproductive capacity of bulls. | 1984 | Am. J. Vet. Res. | pmid:6084431 |
Gyles C et al. | In vivo transfer of an Escherichia coli enterotoxin plasmid possessing genes for drug resistance. | 1978 | Am. J. Vet. Res. | pmid:358869 |
McElroy DE et al. | Pharmacokinetics of oxytetracycline hydrochloride in rabbits. | 1987 | Am. J. Vet. Res. | pmid:3631718 |
BARNES LE | Oxytetracycline in bovine mastitis. II. Milk levels following local and parenteral administration. | 1956 | Am. J. Vet. Res. | pmid:13283224 |
Anderson KL et al. | Potential for oxytetracycline administration by three routes to cause milk residues in lactating cows, as detected by radioimmunoassay (Charm II) and high-performance liquid chromatography test methods. | 1995 | Am. J. Vet. Res. | pmid:7695153 |
Moats WA et al. | Comparison of a radioimmunoassay (Charm II) test with high-performance liquid chromatography for detection of oxytetracycline residues in milk samples from lactating cattle. | 1995 | Am. J. Vet. Res. | pmid:7653890 |
Simpson CF | Morphologic alteration of Paranaplasma caudata following treatment of calves with oxytetracycline. | 1977 | Am. J. Vet. Res. | pmid:931133 |
Wintz LR et al. | Age-dependent effects of systemic administration of oxytetracycline on the viscoelastic properties of rat tail tendons as a mechanistic basis for pharmacological treatment of flexural limb deformities in foals. | 2012 | Am. J. Vet. Res. | pmid:23176422 |
Smith JA and George LW | Treatment of acute ocular Moraxella bovis infections in calves with a parenterally administered long-acting oxytetracycline formulation. | 1985 | Am. J. Vet. Res. | pmid:4014830 |
Milward FW et al. | Effectiveness of various therapeutic regimens for bovine brucellosis. | 1984 | Am. J. Vet. Res. | pmid:6208830 |
Fecteau KA and Eiler H | Evaluation of injections of collagenase and oxytetracycline via the umbilical artery as treatment for retained placenta in cattle. | 1996 | Am. J. Vet. Res. | pmid:8712518 |
KILLOUGH JH and MAGILL GB | A comparative study of fumagillin and oxytetracycline in amebiasis. | 1954 | Am. J. Trop. Med. Hyg. | pmid:13207553 |
Albach RA et al. | A comparison of in vitro drug sensitivities of strains of entamoeba which grow at 37 degrees C and at room temperature. | 1966 | Am. J. Trop. Med. Hyg. | pmid:5959098 |
GELFAND M and ALVES WD | Terramycin in schistosomiasis; a trial in six cases. | 1953 | Am. J. Trop. Med. Hyg. | pmid:13007928 |
WEINSTEIN PP et al. | Treatment of a case of balantidial dysentery with terramycin. | 1952 | Am. J. Trop. Med. Hyg. | pmid:12996748 |
LEWIS RA et al. | Antibiotic dietary supplements in the therapy of childhood protein malnutrition. | 1956 | Am. J. Trop. Med. Hyg. | pmid:13327183 |
WILLIAMS RW | The growth stimulating effect of APF, terramycin hydrochloride, vitamin B12 and an undetermined factor X upon Aedes aegypti (L) Diptera, Culicidae. | 1953 | Am. J. Trop. Med. Hyg. | pmid:13007931 |
Nfon CK et al. | Lack of resistance after re-exposure of cattle cured of Onchocerca ochengi infection with oxytetracycline. | 2007 | Am. J. Trop. Med. Hyg. | pmid:17255232 |
CAT ND | Terramycin in the treatment of trachoma. | 1952 | Am. J. Trop. Med. Hyg. | pmid:14952704 |
SCHWABE CW et al. | HOST-PARASITE RELATIONSHIPS IN ECHINOCOCCOSIS. IX. IN VITRO SURVIVAL OF HYDATID SCOLICES AND THE EFFECTS OF DRUGS UPON SCOLEX RESPIRATION. | 1963 | Am. J. Trop. Med. Hyg. | pmid:14044745 |
MOST H and VAN ASSENDELFT F | Laboratory and clinical observations on the effect of terramycin in the treatment of amebiasis. | 1951 | Am. J. Trop. Med. Hyg. | pmid:14829737 |
TOBIE JE et al. | Laboratory results on the efficacy of terramycin, aureomycin and bacitracin in the treatment of asymptomatic amebiasis. | 1951 | Am. J. Trop. Med. Hyg. | pmid:14857244 |
HIGGINS AR et al. | Studies in shigellosis. IV. A controlled trial of sulfadiazine, dihydrostreptomycin and oxytetracycline as long term prophylaxis agents in a highly endemic environment for shigellosis. | 1955 | Am. J. Trop. Med. Hyg. | pmid:14361908 |
PREZYNA AP et al. | Treatment of scrub typhus in the Pescadores Islands with chloramphenicol, aureomycin and terramycin. | 1954 | Am. J. Trop. Med. Hyg. | pmid:13180818 |
HOEKENGA MT | Terramycin treatment of balantidiasis in Honduras. | 1953 | Am. J. Trop. Med. Hyg. | pmid:13040661 |
Williams TW et al. | Serratia marcescens as a postoperative pathogen. | 1971 | Am. J. Surg. | pmid:4326385 |
DIAMOND JJ and IMPINK RR | Intraperitoneal administration of terramycin in the treatment of generalized peritonitis. | 1957 | Am. J. Surg. | pmid:13403068 |
Dillon ML and Bowling KA | Effect of antibiotics on wound and stool cultures. Comparison of intravenous terramycin with other antibiotics. | 1967 | Am. J. Surg. | pmid:5334435 |
ALLEN RF | A study of the effect of terramycin on the intestinal flora, with special reference to the accompanying side effects. | 1953 | Am. J. Surg. | pmid:13104764 |
Orlowski T et al. | Mechanical arterial suture in contaminated wounds. | 1973 | Am. J. Surg. | pmid:4714778 |
EICHENWALD HF and SHINEFIELD HR | RATIONAL USE OF ANTIBIOTICS. | 1964 | Am. J. Surg. | pmid:14129331 |
Bowden JJ et al. | Dexamethasone and oxytetracycline reverse the potentiation of neurogenic inflammation in airways of rats with Mycoplasma pulmonis infection. | 1994 | Am. J. Respir. Crit. Care Med. | pmid:7524980 |
Guzzo J et al. | Tetracycline-induced inhibition of Na+ transport in the toad urinary bladder. | 1978 | Am. J. Physiol. | pmid:100018 |
Lanman RC et al. | Hepatic uptake and biliary excretion of tetracycline in the rat. | 1973 | Am. J. Physiol. | pmid:4745227 |
Cleall JF et al. | Normal craniofacial skeletal growth of the rat. | 1968 | Am. J. Phys. Anthropol. | pmid:4178215 |
FURTH FW et al. | The effect of aureomycin and terramycin on the X-radiated rat. | 1952 Mar-Apr | Am. J. Pathol. | pmid:14903050 |
COULTER MP et al. | Therapy of the x-irradiation syndrome with terramycin. | 1952 Sep-Oct | Am. J. Pathol. | pmid:12976528 |
Krause U et al. | Aqueous humor penetration of alpha-deoxyoxytetracycline (doxycycline) in man. | 1972 | Am. J. Ophthalmol. | pmid:5064423 |
Hardy D et al. | The cytology of conjunctival smears from aboriginal school children at Yalata, South Australia. | 1967 | Am. J. Ophthalmol. | pmid:6025178 |
Aratoon V | Surgery of pterygium by conjunctival pedicle flap. | 1967 | Am. J. Ophthalmol. | pmid:6027354 |
ATKINSON WS | Half glasses for aphakia. | 1955 | Am. J. Ophthalmol. | pmid:13228542 |
TOWN AE | Ophthalmic use of terramycin. | 1951 | Am. J. Ophthalmol. | pmid:14829487 |
Hanna C et al. | The effect of ophthalmic ointments on corneal wound healing. | 1973 | Am. J. Ophthalmol. | pmid:4353441 |
Fraunfelder FT et al. | Entrapment of ophthalmic ointment in the cornea. | 1973 | Am. J. Ophthalmol. | pmid:4355254 |
PILKERTON R et al. | Intraocular drug levels achieved by a method of retrograde arterial perfusion. | 1963 | Am. J. Ophthalmol. | pmid:13943598 |
LOCATCHER-KHORAZO D | The effect on the ocular bacterial flora of local treatment with chloromycetin (chloramphenicol), terramycin or penicillin-streptomycin ophthalmic ointments in preoperative cataract cases and miscellaneous infections. | 1953 | Am. J. Ophthalmol. | pmid:13030659 |
GELLER HO and THYGESON P | Aureomycine, chloromycetin, and terramycin in experimental herpes-simplex virus infections. | 1951 | Am. J. Ophthalmol. | pmid:14829527 |
KURZ GH | RETINOPATHY OF OBSCURE (TOXIC?) ORIGIN IN HODGKIN'S DISEASE. | 1964 | Am. J. Ophthalmol. | pmid:14123443 |
DICKINSON RH | Ophthalmic use of terramycin and hydrocortisone. | 1955 | Am. J. Ophthalmol. | pmid:14376470 |
ORMSBY HL et al. | Topical therapy in inclusion conjunctivitis. | 1952 | Am. J. Ophthalmol. | pmid:13007754 |
Simmons RE and O'Rourke J | Intra-arterial infusion therapy of pseudomonas and staphylococcal endophthalmitis in dogs. | 1968 | Am. J. Ophthalmol. | pmid:4969585 |
SMITH OW et al. | The effect of oxytetracycline in pregnancy complicated by glomerular nephritis: a case study. | 1954 | Am. J. Obstet. Gynecol. | pmid:13171424 |
SHAPIRO LH and LENTZ JW | GONORRHEA TREATED WITH OXYTETRACYCLINE. PRELIMINARY REPORT ON THE USE OF VARIOUS DOSAGES IN WOMEN. | 1963 | Am. J. Obstet. Gynecol. | pmid:14056192 |
Silverman M and Okun R | Oxytetracycline-nystatin in the prevention of candidal vaginitis. | 1971 | Am. J. Obstet. Gynecol. | pmid:4937726 |
Shapiro LH and Lentz JW | Final report on the effectiveness of oxytetracycline in the treatment of gonorrhea in females. | 1966 | Am. J. Obstet. Gynecol. | pmid:5903676 |
SHAPIRO LH | Preliminary report of utilization of intramuscular oxytetracycline for treatment of gonorrhea in women. | 1962 | Am. J. Obstet. Gynecol. | pmid:13911301 |
MIDDLETON TF | A clinical evaluation of 25 cases treated with terramycin intramuscular. | 1955 | Am. J. Obstet. Gynecol. | pmid:14361557 |
PRINCE LN et al. | THE EVALUATION OF OXYTETRACYCLINE IN THE TREATMENT OF GONORRHEA IN THE PRENATAL PATIENT. A PRELIMINARY REPORT. | 1964 | Am. J. Obstet. Gynecol. | pmid:14215876 |
Stropes L et al. | Multiple recurrences of nocardial pneumonia. | 1980 Sep-Oct | Am. J. Med. Sci. | pmid:7001904 |
Steigbigel NH et al. | Susceptibility of common pathogenic bacteria to seven tetracycline antibiotics in vitro. | 1968 | Am. J. Med. Sci. | pmid:4384524 |
Massell BF et al. | Temporary suppression of penicillinase-producing staphylococci in the throat flora by oxytetracycline. | 1966 | Am. J. Med. Sci. | pmid:5918197 |
CASTANEDA MR and CARRILLO-CARDENAS C | A new approach to treatment of brucellosis. | 1953 | Am. J. Med. Sci. | pmid:13104400 |
SENECA H and BERGENDAHL E | The synergistic amebicidal effect of tetracycline, oxytetracycline and carbomycin on cultures of Endameba histolytica. | 1954 | Am. J. Med. Sci. | pmid:13171377 |
MOUNTAIN DC and KRUMENACHER FP | Oral undecylinic acid in the prevention of the so-called monilial complications secondary to the use of aureomycin, chloramphenicol and terramycin. | 1953 | Am. J. Med. Sci. | pmid:13030464 |
MORTON HS et al. | The value of oral terramycin in pre-operative preparation of the gut. | 1953 | Am. J. Med. Sci. | pmid:13057858 |