oxytetracycline is a lipid of Polyketides (PK) class. Oxytetracycline is associated with abnormalities such as Infection, X-linked centronuclear myopathy, Bacterial Infections, Heart failure and Onchocerciasis. The involved functions are known as Anabolism, physiological aspects, Transcription, Genetic, Fermentation and Transcriptional Activation. Oxytetracycline often locates in Chromosomes, Flank (surface region), Entire bony skeleton, Bone Marrow and Body tissue. The associated genes with oxytetracycline are Polypeptides, Homologous Gene, Gene Clusters, Locus and CYCS gene. The related lipids are LH 1 and Lipid Peroxides. The related experimental models are Disease model.
To understand associated biological information of oxytetracycline, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
oxytetracycline is suspected in Infection, Helminthiasis, Nodule, Bacterial Infections, Yeast infection, pathologic fistula and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with oxytetracycline
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Disease model are used in the study 'A molecular ecological approach to the detection and designation of the etiological agents of a model polymicrobial disease.' (Antiabong JF et al., 2013).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Conforti P et al. | [Diffusion of antibiotics in central nervous system tissue (preliminary study)]. | 1971 Jul-Sep | Minerva Neurochir | pmid:5144628 |
LENTI G and FAZIO M | [Clinical observations on the use of terramycin]. | 1951 | Minerva Med. | pmid:14863247 |
DINA MA and POZZUOLI R | [THE USE OF TETRACYCLINE AS FLUOROCHROME AND APPLICATIONS IN ONCOLOGIC DIAGNOSIS]. | 1964 | Minerva Med. | pmid:14231298 |
Grasso E and Mondino P | [Doxycycline in brucellar infection]. | 1972 | Minerva Med. | pmid:5049880 |
Bariffi F and Marcatili S | [Clinical results of the use of doxycycline in the treatment of acute and chronic bronchopneumopathies]. | 1972 | Minerva Med. | pmid:5012343 |
[Pharmacological aspects of terramycin; toxicity. Review of the literature]. | 1951 | Minerva Med. | pmid:14910351 | |
Pasquale A et al. | [Clinico-experimental study of a new tetracycline: doxycycline (alpha-6-desoxy-5-oxytetracycline)]. | 1971 | Minerva Med. | pmid:5285339 |
Ciappi G et al. | [Clinical and functional aspects of combined antibiotic and sercretolytic treatment in the exacerbation of chronic bronchopneumonias]. | 1971 | Minerva Med. | pmid:5136614 |
Meciani L et al. | [Use of doxycycline in angiosurgery patients]. | 1971 | Minerva Med. | pmid:5566184 |
Giuliani V et al. | [The use of a new antibiotic for local administration in burns]. | 1980 | Minerva Med. | pmid:7393469 |
Di Nola F et al. | [Treatment of tetanus: methyldiazepinone as a sedative drug]. | 1971 | Minerva Med. | pmid:4397548 |
GEMMI M and BANCALE A | [Cure of three cases of pulmonary abscess treated with terramycin]. | 1952 | Minerva Med. | pmid:13025032 |
GIUNCHI G | [Treatment of Q fever with terramycin]. | 1951 | Minerva Med. | pmid:14842935 |
Meoni S et al. | [Bisolvomycin in the theray of chronic bronchitis]. | 1971 | Minerva Med. | pmid:5548390 |
PATELSKI RA | [Present status of terramycin]. | 1950 | Minerva Med. | pmid:14815473 |
ABRATE M and LALLONI R | [CONTRIBUTION TO THE USE OF INTRAVENOUS CHLOROPROMAZINE IN TETANUS]. | 1963 | Minerva Med. | pmid:14124191 |
SEREMBE M | [Intrapleural oxytetracycline in the therapy of tuberculous empyema]. | 1956 | Minerva Med. | pmid:13348302 |
IZAR G and GASPERSIC A | [Terramycin in bacterial and protozoal infections]. | 1951 | Minerva Med. | pmid:14863246 |
PERRINI F | [Terramycin in therapy of gynecological phlogoses]. | 1953 | Minerva Ginecol | pmid:13071788 |
OLIVELLI F | [Vaginal absorption and elimination of terramycin]. | 1953 | Minerva Ginecol | pmid:13071826 |
Grio R et al. | [Antibacterial activity of meclocycline (Mecloderm) in non-specific vaginitis. Study of 262 cases]. | 1986 | Minerva Ginecol | pmid:3703368 |
Facchini V et al. | [Activity of topical flunoxaprofen in nonspecific vaginitis. Comparison with meclocycline sulfosalicylate]. | 1989 | Minerva Ginecol | pmid:2626206 |
Cavanenghi D et al. | [Pseudomembranous colitis induced by clindamycin-lincomycin combination. Description of a clinical case]. | 1985 Apr-Jun | Minerva Dietol Gastroenterol | pmid:4034041 |
MONTILLI G | [The use of terramycin in dermatology]. | 1953 | Minerva Dermatol | pmid:13144457 |
MONTILLI G | [Treatment of post-gonococcal urethritis with terramycin]. | 1953 | Minerva Dermatol | pmid:13086696 |
MEL C | [Comparative statistical evaluation of the therapeutic efficacy of oxytetracycline and of tetracycline in surgical infections]. | 1956 | Minerva Chir | pmid:13399845 |
GENNAI N | [Terramycin treatment of acute hematogenic osteomyelitis; case report]. | 1956 | Minerva Chir | pmid:13378133 |
Damele C | [Therapeutical effect of doxycycline in surgery]. | 1971 | Minerva Chir | pmid:5579725 |
Lobello R | [Postoperative pulmonary complications following abdominal surgery. Study on the preventive use of a bronchosecretolytic agent associated with an antibiotic]. | 1975 | Minerva Chir | pmid:1093063 |
SOAVE F | [Diffuse bacterial peritonitis of the child & endoperitoneal treatment with oxytetracycline & tetracycline]. | 1958 | Minerva Chir | pmid:13565464 |
FERGUSON C et al. | Local use of antibiotics in chronic urethritis. | 1952 | Mil Surg | pmid:14956671 |
KORMANO M | FLUORESCENT STAINING OF SPERMATID HEADS WITH OXYTETRACYCLINE. | 1965 | Mikroskopie | pmid:14305659 |
Willke A et al. | [Susceptibility of Vibrio cholerae El-Tor strains to various antibiotics]. | 1988 | Mikrobiyol Bul | pmid:3273600 |
Penzikova GA et al. | [The nucleases of oxytetracycline producing actinomycetes]. | 1976 Mar-Apr | Mikrobiologiia | pmid:819760 |
ORLOVA NV et al. | [DISTRIBUTION AMONG ACTINOMYCETES, FUNGI AND BACTERIA OF SUBSTANCES STIMULATING OXYTETRACYCLINE PRODUCTION BY MUTANTS OF ACT. RIMOSUS T-572]. | 1964 Nov-Dec | Mikrobiologiia | pmid:14336844 |
Orlova NV and Andrianova MB | [Oxytetracycline biosynthesis by Actinomyces rimosus on media with differenti carbohydrates]. | 1966 Jan-Feb | Mikrobiologiia | pmid:5982563 |
ZAITSEVA ZM and ORLOVA NV | [Studies on synthesis of oxytetracycline (terramycin) by Actinomyces rimosus LS-T-118 cultures]. | 1959 Mar-Apr | Mikrobiologiia | pmid:13666437 |
ORLOVA NV | [Effect of oils on oxytetracycline biosynthesis by Act. rimosus cultures]. | 1961 Jul-Aug | Mikrobiologiia | pmid:14482291 |
KOROTIAEV AI | [Effect of chloramphenicol (levomycetin), streptomycin and oxytetracycline on the activity of the acetylation enzyme]. | 1962 May-Jun | Mikrobiologiia | pmid:14458516 |
ORLOVA NV and VERKHOVTSEVA TP | [Significance of phosphorus, nitrogen and lactic acid of corn extract in biosynthesis of oxytetracycline]. | 1959 Jul-Aug | Mikrobiologiia | pmid:14429067 |
ZAITSEVA ZM and ORLOVA NV | [Studies on physiological principles of a mutant of Act. rimosus LS-T-572 related to the biosynthesis of oxytetracycline]. | 1962 May-Jun | Mikrobiologiia | pmid:14009630 |
RautenshteÄn IaI et al. | [Occurrence of lysis in a culture of Actinomyces rimosus]. | 1972 Nov-Dec | Mikrobiologiia | pmid:4657959 |
RautenshteÄn IaI et al. | [Factors causing lysis of an Actinomyces rimosus culture, the producer of the antibiotic, oxytetracycline]. | 1975 Sep-Oct | Mikrobiologiia | pmid:1634 |
Vyshepan ED and Meleshkina LV | [Induction of protein synthesis in a microbial cell by foreign RNA]. | 1967 Nov-Dec | Mikrobiologiia | pmid:5618851 |
Engel'brekht G and Makh F | [Physiological study on the interrelation of fat metabolism and oxytetracycline biosynthesis in Actinomyces rimosus]. | 1967 Nov-Dec | Mikrobiologiia | pmid:5618863 |
NOVIKOV VM | [ON THE EFFECT OF ANTIBIOTICS ON ANTHRAX BACILLUS IN VITRO]. | 1963 | Mikrobiol Zh | pmid:14105475 |
Borisova VM and DvoÄnos LM | [The participation of fungus peroxidase in the detoxication of respiratory toxins]. | 1971 May-Jun | Mikrobiol Zh | pmid:5152467 |
Kucher VI | [Resistance of staphylococci to ethonium and some antibiotics]. | 1970 May-Jun | Mikrobiol Zh | pmid:5205114 |
Ginzburg TS and Drabkina RO | [The antitubercular activity of oxytetracycline]. | 1969 Jul-Sep | Mikrobiol Zh | pmid:4996128 |
Klimchuk MD | [Comparative study of antibiotics on rickettsia Provazekii]. | 1967 Mar-Apr | Mikrobiol Zh | pmid:4979719 |
Gravius B et al. | The 387 kb linear plasmid pPZG101 of Streptomyces rimosus and its interactions with the chromosome. | 1994 | Microbiology (Reading, Engl.) | pmid:7952179 |
Wang P et al. | Genetic characterization of enzymes involved in the priming steps of oxytetracycline biosynthesis in Streptomyces rimosus. | 2011 | Microbiology (Reading, Engl.) | pmid:21622525 |
Pandza K et al. | Physical mapping shows that the unstable oxytetracycline gene cluster of Streptomyces rimosus lies close to one end of the linear chromosome. | 1997 | Microbiology (Reading, Engl.) | pmid:9168599 |
Hranueli D et al. | A comparative study of protoplast preparation and regeneration in Streptomyces rimosus and Streptomyces lividans. | 1986 | Microbiologica | pmid:3747855 |
Petković H et al. | Genetics of Streptomyces rimosus, the oxytetracycline producer. | 2006 | Microbiol. Mol. Biol. Rev. | pmid:16959966 |
Ishihara K et al. | Distribution of antimicrobial-resistant lactic acid bacteria in natural cheese in Japan. | 2013 | Microbiol. Immunol. | pmid:23930694 |
Nakamura M et al. | Drug resistance and R plasmids in Escherichia coli strains isolated from imported pet birds. | 1980 | Microbiol. Immunol. | pmid:6163947 |
Nfon CK et al. | Eosinophils contribute to killing of adult Onchocerca ochengi within onchocercomata following elimination of Wolbachia. | 2006 | Microbes Infect. | pmid:16962357 |
Zeineldin M et al. | Impact of parenteral antimicrobial administration on the structure and diversity of the fecal microbiota of growing pigs. | 2018 | Microb. Pathog. | pmid:29578067 |
Seyfried EE et al. | Occurrence of tetracycline resistance genes in aquaculture facilities with varying use of oxytetracycline. | 2010 | Microb. Ecol. | pmid:20217406 |
Lin L et al. | Proteomic Analysis of Alterations in Aeromonas hydrophila Outer Membrane Proteins in Response to Oxytetracycline Stress. | 2018 | Microb. Drug Resist. | pmid:29356594 |
Yin S et al. | Identification of a cluster-situated activator of oxytetracycline biosynthesis and manipulation of its expression for improved oxytetracycline production in Streptomyces rimosus. | 2015 | Microb. Cell Fact. | pmid:25886456 |
Tsuji K | High-pressure liquid chromatography of antibiotics. | 1975 | Meth. Enzymol. | pmid:48995 |
Tam CS et al. | Bone apposition rate as an index of bone metabolism. | 1978 | Metab. Clin. Exp. | pmid:622046 |
DE MAGALHAES O | [Better curative therapy of exanthematous typhys in Brazil (Piza-Meyer-Gomes disease)]. | 1953 | Mem. Inst. Oswaldo Cruz | pmid:13185064 |
ROSTALSKI M and SCHREYER CH | [Not Available]. | 1956 | Medizinische | pmid:13399696 |
KOCH E et al. | [Clinical manifestations and pathogenesis of the terramycin intoxication]. | 1954 | Medizinische | pmid:13176004 |
STOTTER G | [Experiences in therapeutic use of terramycin]. | 1952 | Medizinische | pmid:12992405 |
STOTTER G | [Experiences in therapeutic use of terramycin]. | 1952 | Medizinische | pmid:12992419 |
BAUER KM and WUNDT W | [Studies on blood level and excretion following intramuscular application of terramycin]. | 1954 | Medizinische | pmid:13235107 |
LUTZEYER W et al. | [Oxytetracycline therapy in urology with special consideration of renal function]. | 1958 | Medizinische | pmid:13516284 |
VON PEIN H | [Therapeutic results with terramycin]. | 1952 | Medizinische | pmid:13001800 |
SCHAPER G | [Hospital dyspepsia and management with terramycin]. | 1955 | Medizinische | pmid:13287656 |
GROSS R | [Experiences with terramycin therapy in gynecology. I]. | 1955 | Medizinische | pmid:13287677 |
GROSS R | [Experiences with terramycin therapy in gynecology. II]. | 1955 | Medizinische | pmid:13287688 |
BESSERER G | [Local use of cortisone preparations in the gynecological practice]. | 1958 | Medizinische | pmid:13599926 |
VON BLUMRODER WO | [A case of osteomyelitis complicating scarlet fever treated with terramycin]. | 1955 | Medizinische | pmid:14383091 |
VALDES LA VALLINA F | [A new medical compound in urinary infections. Clinical observations]. | 1959 | Medicina (Mex) | pmid:13840774 |
RUIZ SANCHEZ F et al. | [Two cases of malaria treated with terramycin; clinical note]. | 1951 | Medicina (Mex) | pmid:24541302 |
SAUZA H | [Intramuscular terramycin and tetracyn in the treatment of whooping cough]. | 1956 | Medicina (Mex) | pmid:13368962 |
MALDONADO HERNANDEZ J | [Pyelonephritis during pregnancy. Evaluation of a new medicamentous combination (preliminary report)]. | 1962 | Medicina (Mex) | pmid:14468841 |
JORDAN R | [Topical use of the oxytetracycline-hydrocortisone combination in the treatment of acute gingivitis]. | 1962 | Medicina (Mex) | pmid:14452442 |
GAYTAN V | [Intraperitoneal terramycin in therapy of generalized peritonitis]. | 1959 | Medicina (Mex) | pmid:13632301 |
SAAVEDRA AMARO S | [Oxytetracycline in neurotraumatology]. | 1959 | Medicina (Mex) | pmid:13632305 |
SAAVEDRA AMARO S and LOPEZ ZEPEDA L | [Clinical evaluation of the antibiotic association oxytetracycline-oleandomycin in the treatment of various infections in medical and surgical practice]. | 1958 | Medicina (Mex) | pmid:13621976 |
RUIZ SANCHEZ F et al. | [Treatment of amebic dysentery with terramycin; preliminary note]. | 1950 | Medicina (Mex) | pmid:14775365 |
MELLADO JF | [Use of oxytetracycline (terramycin) in the surgical treatment of exposed fractures]. | 1958 | Medicina (Mex) | pmid:13599868 |
SALDANA SOTOMAYOR F | [Oxytetracycline therapy of severe bronchopneumonia in infants and pre-school children]. | 1958 | Medicina (Mex) | pmid:13599871 |
GONZALEZ CUESTA A | [Treatment of mastitis with the association of oxytetracycline and oxytocin]. | 1960 | Medicina (Mex) | pmid:13850985 |
SAUZA H | [Intramuscular terramycin in the treatment of whooping-cough]. | 1956 | Medicina (Mex) | pmid:13347590 |
UCARLUCAS JM | [DISENTERIA AMEBIANA]. | 1963 | Medicina (Madr) | pmid:14089865 |
SIERRA J | [OXYTETRACYCLINE-POLYMYXIN B IN THE TREATMENT OF CHRONIC SUPPURATIVE OTITIS MEDIA WITH ASSOCIATED FUNGI]. | 1963 | Medicina (Madr) | pmid:14092173 |
[Hypoglycemic acition of the oxytetracycline]. | 1967 Mar-Apr | Medicina (B Aires) | pmid:5600647 | |
FLOREZ TASCON FJ et al. | [Terramycin]. | 1951 | Medicamenta (Madr) | pmid:14852347 |
REY BUSTO M | [Treatment of enterobiasis with terramycin]. | 1953 | Medicamenta (Madr) | pmid:13054158 |
Bertić BM | [Therapeutic use of vibramycin in obstetrics]. | 1976 | Med. Pregl. | pmid:1256373 |
ZETZMANN M | [New method in the treatment of uterine cervix erosion]. | 1957 | Med. Klin. (Munich) | pmid:13399766 |
RIEDERER VON PAAR R and SCHWEIER P | [Oral oxytetracyline in pediatrics]. | 1958 | Med. Klin. (Munich) | pmid:13589595 |
GUNTHER HE | [Treatment of adnexitis with cortisones (prednisolone)]. | 1958 | Med. Klin. (Munich) | pmid:13565332 |
WEBER F | [Experience with oxytetracycline in the treatment of osteomyelitis]. | 1955 | Med. Klin. (Munich) | pmid:14383175 |