oxytetracycline is a lipid of Polyketides (PK) class. Oxytetracycline is associated with abnormalities such as Infection, X-linked centronuclear myopathy, Bacterial Infections, Heart failure and Onchocerciasis. The involved functions are known as Anabolism, physiological aspects, Transcription, Genetic, Fermentation and Transcriptional Activation. Oxytetracycline often locates in Chromosomes, Flank (surface region), Entire bony skeleton, Bone Marrow and Body tissue. The associated genes with oxytetracycline are Polypeptides, Homologous Gene, Gene Clusters, Locus and CYCS gene. The related lipids are LH 1 and Lipid Peroxides. The related experimental models are Disease model.
To understand associated biological information of oxytetracycline, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
oxytetracycline is suspected in Infection, Helminthiasis, Nodule, Bacterial Infections, Yeast infection, pathologic fistula and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with oxytetracycline
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Disease model are used in the study 'A molecular ecological approach to the detection and designation of the etiological agents of a model polymicrobial disease.' (Antiabong JF et al., 2013).
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Authors | Title | Published | Journal | PubMed Link |
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Magonigle RA and Newby TJ | Response of cattle upon reexposure to Anaplasma marginale after elimination of chronic carrier infections. | 1984 | Am. J. Vet. Res. | pmid:6731981 |
Teare JA et al. | Pharmacokinetics of a long-acting oxytetracycline preparation in ring-necked pheasants, great horned owls, and Amazon parrots. | 1985 | Am. J. Vet. Res. | pmid:4083606 |
Nicoletti P et al. | Efficacy of various treatment regimens, using liposomal streptomycin in cows with brucellosis. | 1989 | Am. J. Vet. Res. | pmid:2505648 |
Palmer GH et al. | Absorption in calves of amoxicillin, ampicillin, and oxytetracycline given in milk replacer, water, or an oral rehydration formulation. | 1983 | Am. J. Vet. Res. | pmid:6824227 |
Magonigle RA et al. | Efficacy of a new oxytetracycline formulation against clinical anaplasmosis. | 1978 | Am. J. Vet. Res. | pmid:697150 |
Wooley RE et al. | Inhibitory effects of combinations of oxytetracycline, dimethyl sulfoxide, and EDTA-tromethamine on Escherichia coli. | 1981 | Am. J. Vet. Res. | pmid:6802044 |
Hatch RC et al. | Induced acute aflatoxicosis in goats: treatment with activated charcoal or dual combinations of oxytetracycline, stanozolol, and activated charcoal. | 1982 | Am. J. Vet. Res. | pmid:6803625 |
Toutain PL and Raynaud JP | Pharmacokinetics of oxytetracycline in young cattle: comparison of conventional vs long-acting formulations. | 1983 | Am. J. Vet. Res. | pmid:6881660 |
Ames TR et al. | Oxytetracycline concentrations in healthy and diseased calves. | 1983 | Am. J. Vet. Res. | pmid:6881673 |
Kuttler KL and Simpson JE | Relative efficacy of two oxytetracycline formulations and doxycycline in the treatment of acute anaplasmosis in splenectomized calves. | 1978 | Am. J. Vet. Res. | pmid:629473 |
Clark JD et al. | Effects of various treatments on induced chronic aflatoxicosis in rabbits. | 1982 | Am. J. Vet. Res. | pmid:6807140 |
Wooley RE et al. | Antibacterial action of combinations of oxytetracycline, dimethyl sulfoxide, and EDTA-tromethamine on Proteus, Salmonella, and Aeromonas. | 1982 | Am. J. Vet. Res. | pmid:6807142 |
George LW et al. | Effectiveness of two benzathine cloxacillin formulations for treatment of naturally occurring infectious bovine keratoconjunctivitis. | 1989 | Am. J. Vet. Res. | pmid:2774340 |
Kniffen TS et al. | Bioavailability, pharmacokinetics, and plasma concentration of tetracycline hydrochloride fed to swine. | 1989 | Am. J. Vet. Res. | pmid:2712418 |
Dyer DC | Pharmacokinetics of oxytetracycline in the turkey: evaluation of biliary and urinary excretion. | 1989 | Am. J. Vet. Res. | pmid:2712419 |
Rohde C et al. | Effects of phenylbutazone on bone activity and formation in horses. | 2000 | Am. J. Vet. Res. | pmid:10803649 |
MarÃn CM et al. | Efficacy of long-acting oxytetracycline alone or in combination with streptomycin for treatment of Brucella ovis infection of rams. | 1989 | Am. J. Vet. Res. | pmid:2712423 |
Wooley RE et al. | Attempted reversal of oxytetracycline resistance of Proteus mirabilis by EDTA-tromethamine lavage in experimentally induced canine and feline cystitis. | 1975 | Am. J. Vet. Res. | pmid:811139 |
Bretzlaff KN et al. | Distribution of oxytetracycline in the healthy and diseased postpartum genital tract of cows. | 1983 | Am. J. Vet. Res. | pmid:6869979 |
Bretzlaff KN et al. | Distribution of oxytetracycline in genital tract tissues of postpartum cows given the drug by intravenous and intrauterine routes. | 1983 | Am. J. Vet. Res. | pmid:6869980 |
Kuttler KL | Influence of a second Anaplasma exposure on the success of treatment to eliminate Anaplasma carrier infections in cattle. | 1983 | Am. J. Vet. Res. | pmid:6869997 |
VanEnkevort BA et al. | Alterations in bone remodeling in the femur after medullary reaming and cemented hip arthroplasty in dogs. | 1999 | Am. J. Vet. Res. | pmid:10451197 |
George LW et al. | Comparison of two oxytetracycline formulations in the treatment of laboratory-induced pasteurellosis of pigs. | 1983 | Am. J. Vet. Res. | pmid:6870001 |
Bowen JM and McMullan WC | Influence of induced hypermagnesemia and hypocalcemia on neuromuscular blocking property of oxytetracycline in the horse. | 1975 | Am. J. Vet. Res. | pmid:1147343 |
YODER HW and PACKER RA | Bovine blood serum concentrations of terramycin (Oxytetracycline) following intravenous and intramuscular administration. | 1954 | Am. J. Vet. Res. | pmid:13171501 |
Davis RW et al. | The effects of an oxytetracycline preparation on the thyroid gland: a preliminary report. | 1966 | Am. J. Vet. Res. | pmid:5913021 |
Miller RA and Reimschuessel R | Epidemiologic cutoff values for antimicrobial agents against Aeromonas salmonicida isolates determined by frequency distributions of minimal inhibitory concentration and diameter of zone of inhibition data. | 2006 | Am. J. Vet. Res. | pmid:17078743 |
Owen RA et al. | Effects of transportation, surgery, and antibiotic therapy in ponies infected with Salmonella. | 1983 | Am. J. Vet. Res. | pmid:6337537 |
Kerwin SC et al. | Effect of hyperbaric oxygen treatment on incorporation of an autogenous cancellous bone graft in a nonunion diaphyseal ulnar defect in cats. | 2000 | Am. J. Vet. Res. | pmid:10850847 |
Toofanian F and Targowski S | Experimental production of rabbit mucoid enteritis. | 1983 | Am. J. Vet. Res. | pmid:6346966 |
Ferré PJ et al. | Comparison of ultrasonography and pharmacokinetic analysis of creatine kinase release for quantitative assessment of postinjection muscle damage in sheep. | 2001 | Am. J. Vet. Res. | pmid:11703010 |
Simpson CF | Morphologic alterations of Anaplasma marginale in calves after treatment with oxytetracycline. | 1975 | Am. J. Vet. Res. | pmid:1190584 |
Brown MP and MacCallum FJ | A system of grading ossification in limbs of foals to assist in radiologic interpretation. | 1975 | Am. J. Vet. Res. | pmid:1137212 |
BARNES LE | Oxytetracycline in bovine mastitis. I. Treatment of mastitis. | 1955 | Am. J. Vet. Res. | pmid:13238740 |
Kaneene JB et al. | Drug residues in milk after intrauterine injection of oxytetracycline, lincomycin-spectinomycin, and povidone-iodine in cows with metritis. | 1986 | Am. J. Vet. Res. | pmid:2942064 |
MacNeil JD et al. | Bioassay techniques and high-performance liquid chromatography for detection of oxytetracycline residues in tissues from calves. | 1989 | Am. J. Vet. Res. | pmid:2919831 |
Hewson J et al. | Impact of isoflupredone acetate treatment on clinical signs and weight gain in weanling heifers with experimentally induced Mannheimia haemolytica bronchopneumonia. | 2011 | Am. J. Vet. Res. | pmid:22126689 |
Pindak FF et al. | Incidence and distribution of spirochetes in the digestive tract of dogs. | 1965 | Am. J. Vet. Res. | pmid:5882556 |
Guerra MA and Nicoletti P | Comparison of the susceptibility of Brucella abortus isolates obtained before and after cows were treated with oxytetracycline and streptomycin. | 1986 | Am. J. Vet. Res. | pmid:3099613 |
Bretzlaff KN et al. | Distribution of oxytetracycline in the genital tract of cows. | 1982 | Am. J. Vet. Res. | pmid:7091807 |
Lincoln SD et al. | Bovine anaplasmosis: clinical, hematologic, and serologic manifestations in cows given a long-acting oxytetracycline formulation in the prepatent period. | 1982 | Am. J. Vet. Res. | pmid:7103219 |
Lubbers BV et al. | Effects of two simulated oxytetracycline dosing regimens on horizontal transfer of antimicrobial resistance plasmids in an in vitro pharmacodynamic model. | 2011 | Am. J. Vet. Res. | pmid:21728847 |
Sarmiento JI and Moon HW | Postweaning diarrhea in swine: effects of oxytetracycline on enterotoxigenic Escherichia coli infection. | 1988 | Am. J. Vet. Res. | pmid:3048158 |
Arnoczky SP et al. | In vitro effects of oxytetracycline on matrix metalloproteinase-1 mRNA expression and on collagen gel contraction by cultured myofibroblasts obtained from the accessory ligament of foals. | 2004 | Am. J. Vet. Res. | pmid:15077693 |
Palmer JE et al. | Effect of treatment with oxytetracycline during the acute stages of experimentally induced equine ehrlichial colitis in ponies. | 1992 | Am. J. Vet. Res. | pmid:1476312 |
Oukessou M et al. | Pharmacokinetics and local tolerance of a long-acting oxytetracycline formulation in camels. | 1992 | Am. J. Vet. Res. | pmid:1416372 |
Magonigle RA and Newby TJ | Elimination of naturally acquired chronic Anaplasma marginale infections with a long-acting oxytetracycline injectable. | 1982 | Am. J. Vet. Res. | pmid:7165161 |
Kuttler KL | Efficacy of oxytetracycline and a dithiosemicarbazone in the treatment of bovine anaplasmosis. | 1971 | Am. J. Vet. Res. | pmid:5094519 |
Riner JL et al. | Influence of density and location on degradation of sustained-release boluses given to cattle. | 1982 | Am. J. Vet. Res. | pmid:7181203 |
Hatch RC et al. | Effect of antibacterials, anabolic steroid, and diethyldithiocarbamate on induced acute aflatoxicosis in goats. | 1982 | Am. J. Vet. Res. | pmid:6280533 |
Gross DR et al. | Cardiovascular effects of intravenous administration of propylene glycol and of oxytetracycline in propylene glycol in calves. | 1979 | Am. J. Vet. Res. | pmid:475130 |
Gross DR et al. | Adverse cardiovascular effects of oxytetracycline preparations and vehicles in intact awake calves. | 1981 | Am. J. Vet. Res. | pmid:7294473 |
Abbitt B et al. | Effect of dihydrostreptomycin or oxytetracycline on reproductive capacity of bulls. | 1984 | Am. J. Vet. Res. | pmid:6084431 |
Gyles C et al. | In vivo transfer of an Escherichia coli enterotoxin plasmid possessing genes for drug resistance. | 1978 | Am. J. Vet. Res. | pmid:358869 |
byford RL et al. | Chemoprophylaxis of vector-borne anaplasmosis with sustained-release boluses. | 1981 | Am. J. Vet. Res. | pmid:7340579 |
McElroy DE et al. | Pharmacokinetics of oxytetracycline hydrochloride in rabbits. | 1987 | Am. J. Vet. Res. | pmid:3631718 |
Larson VL and Stowe CM | Plasma and tissue concentrations of oxytetracycline in the horse after intravenous administration. | 1981 | Am. J. Vet. Res. | pmid:7340586 |
BARNES LE | Oxytetracycline in bovine mastitis. II. Milk levels following local and parenteral administration. | 1956 | Am. J. Vet. Res. | pmid:13283224 |
Fielding CL et al. | Evaluation of potential predictor variables for PCR assay diagnosis of Anaplasma phagocytophilum infection in equids in Northern California. | 2018 | Am. J. Vet. Res. | pmid:30085857 |
Edmondson AJ et al. | Survival analysis for evaluation of corneal ulcer healing times in calves with naturally acquired infectious bovine keratoconjunctivitis. | 1989 | Am. J. Vet. Res. | pmid:2764337 |
Anderson KL et al. | Potential for oxytetracycline administration by three routes to cause milk residues in lactating cows, as detected by radioimmunoassay (Charm II) and high-performance liquid chromatography test methods. | 1995 | Am. J. Vet. Res. | pmid:7695153 |
Ames TR and Patterson EB | Oxytetracycline concentrations in plasma and lung of healthy and pneumonic calves, using two oxytetracycline preparations. | 1985 | Am. J. Vet. Res. | pmid:3909863 |
Moats WA et al. | Comparison of a radioimmunoassay (Charm II) test with high-performance liquid chromatography for detection of oxytetracycline residues in milk samples from lactating cattle. | 1995 | Am. J. Vet. Res. | pmid:7653890 |
Simpson CF | Morphologic alteration of Paranaplasma caudata following treatment of calves with oxytetracycline. | 1977 | Am. J. Vet. Res. | pmid:931133 |
Wintz LR et al. | Age-dependent effects of systemic administration of oxytetracycline on the viscoelastic properties of rat tail tendons as a mechanistic basis for pharmacological treatment of flexural limb deformities in foals. | 2012 | Am. J. Vet. Res. | pmid:23176422 |
Button C and Mülders MS | Effects of oxytetracycline in propylene glycol, oxytetracycline in saline solution, and propylene glycol alone on blood ionized calcium and plasma total calcium in sheep. | 1984 | Am. J. Vet. Res. | pmid:6476580 |
Paulsen DB et al. | Use of an indwelling bronchial catheter model of bovine pneumonic pasteurellosis for evaluation of therapeutic efficacy of various compounds. | 1992 | Am. J. Vet. Res. | pmid:1524292 |
Tornquist SJ et al. | Use of a polymerase chain reaction assay to study response to oxytetracycline treatment in experimental Candidatus Mycoplasma haemolamae infection in alpacas. | 2009 | Am. J. Vet. Res. | pmid:19719425 |
Milward FW et al. | Effectiveness of various therapeutic regimens for bovine brucellosis. | 1984 | Am. J. Vet. Res. | pmid:6208830 |
Fecteau KA and Eiler H | Evaluation of injections of collagenase and oxytetracycline via the umbilical artery as treatment for retained placenta in cattle. | 1996 | Am. J. Vet. Res. | pmid:8712518 |
Myers MJ et al. | In vitro modulation of bovine blood neutrophils and mononuclear cells by oxytetracycline. | 1995 | Am. J. Vet. Res. | pmid:8533970 |
Malatinszky I | Two possibilities of further reduction in mortality from tuberculosis. | 1967 | Am. Rev. Respir. Dis. | pmid:6018714 |
Ashegyi B and Malatinszky I | Bronchial pulmonary disease associated with tuberculous lymph nodes. | 1968 | Am. Rev. Respir. Dis. | pmid:5647212 |
Ayvazian LF et al. | Erythrokinetic studies during antimicrobial therapy in pulmonary emphysema. | 1969 | Am. Rev. Respir. Dis. | pmid:5810804 |
Albert WC and Inkley SR | The efficacy of steroid therapy in the treatment of experimental kerosene pneumonitis. | 1968 | Am. Rev. Respir. Dis. | pmid:5683485 |
CONN HO et al. | ETHIONAMIDE-INDUCED HEPATITIS. A REVIEW WITH A REPORT OF AN ADDITIONAL CASE. | 1964 | Am. Rev. Respir. Dis. | pmid:14221666 |
PHILLIPS S | RELAPSE IN TREATED CASES OF PULMONARY TUBERCULOSIS. I. THREE-YEAR FOLLOW-UP OF 312 PATIENTS DISCHARGED FROM THE HOSPITAL WITH MEDICAL APPROVAL, 1947-1954. | 1964 | Am. Rev. Respir. Dis. | pmid:14178617 |
BUMBALO TS et al. | Pinworm infection (enterobiasis) in children; a comparative study of four oxyuricides. | 1953 | AMA Am J Dis Child | pmid:13103773 |
BALER GR | Oxytetracycline intramuscular in the treatment of early syphilis. | 1956 | AMA Arch Derm | pmid:13312644 |
BAREFOOT SW | Oxytetracycline hydrochloride-polymyxin B sulfate topical powder. | 1959 | AMA Arch Derm | pmid:13636430 |
STRITZLER C and FRANK L | Topical hydrocortisone-oxytetracycline therapy. | 1955 | AMA Arch Derm | pmid:14375396 |
SNYDER W | Terramycin therapy of eczema vaccinatum; report of a case. | 1951 | AMA Arch Derm Syphilol | pmid:14867923 |
NIEDELMAN ML | Molluscum contagiosum treated with oxytetracycline (terramycin). | 1953 | AMA Arch Derm Syphilol | pmid:13007184 |
MOPPER C | Terramycin therapy of molluscum contagiosum. | 1952 | AMA Arch Derm Syphilol | pmid:14914183 |
TSCHAN DN and WRIGHT CS | Safety of systemic oxytetracycline (terramycin) therapy following or with topical therapy. | 1954 | AMA Arch Derm Syphilol | pmid:13147576 |
ZELIGMAN I and SINESI SJ | Carbuncle caused by Gaffkya tetragena treated with oxytetracycline (terramycin). | 1953 | AMA Arch Derm Syphilol | pmid:13091374 |
WRIGHT CS and TSCHAN DN | Local oxytetracycline (terramycin) therapy of skin infections. | 1953 | AMA Arch Derm Syphilol | pmid:13029894 |
FERGUSON BC and TYLER MD | Edema and hypoproteinemia following diarrhea associated with oxytetracycline therapy. | 1954 | AMA Arch Intern Med | pmid:13196730 |
WOMACK CR et al. | Terramycin therapy of urinary tract infections. | 1952 | AMA Arch Intern Med | pmid:14884789 |
MAGILL GB and KILLOUGH JH | Oxytetracycline-streptomycin therapy in brucellosis due to Brucella melitensis. | 1953 | AMA Arch Intern Med | pmid:13016039 |
BATEMAN JC et al. | Fatal complications of intensive antibiotic therapy in patients with neoplastic disease. | 1952 | AMA Arch Intern Med | pmid:12996105 |
KNIGHT V et al. | Terramycin in treatment of human brucellosis. | 1951 | AMA Arch Intern Med | pmid:14829089 |
DI CAPRIO JM and RANTZ LA | Effects of terramycin on the bacterial flora of the bowel in man. | 1950 | AMA Arch Intern Med | pmid:14770585 |
MITSUI Y et al. | Terramycin in the treatment of trachoma. | 1951 | AMA Arch Ophthalmol | pmid:14868042 |
DOUVAS NG et al. | Role of terramycin in ophthalmology. | 1951 | AMA Arch Ophthalmol | pmid:14902193 |
CANNON EJ et al. | Studies on the intraocular penetration and toxicity of terramycin. | 1952 | AMA Arch Ophthalmol | pmid:14902207 |
FOLBRE TW et al. | Rhinoscleroma successfully treated with oxytetracycline (terramycin). | 1954 | AMA Arch Otolaryngol | pmid:13196799 |
BELDING HH | Acute perforated diverticulitis of the sigmoid colon with generalized peritonitis. | 1957 | AMA Arch Surg | pmid:13410323 |
REISS E et al. | Terramycin in treatment of peritonitis. | 1952 | AMA Arch Surg | pmid:14877394 |
MATHIEU PL | Comparison study: silver nitrate and oxytetracycline in newborn eyes; a comparison of the incidence of conjunctivitis following the instillation of silver nitrate or oxytetracycline into the eyes of newborn infants. | 1958 | AMA J Dis Child | pmid:13532153 |