oxytetracycline is a lipid of Polyketides (PK) class. Oxytetracycline is associated with abnormalities such as Infection, X-linked centronuclear myopathy, Bacterial Infections, Heart failure and Onchocerciasis. The involved functions are known as Anabolism, physiological aspects, Transcription, Genetic, Fermentation and Transcriptional Activation. Oxytetracycline often locates in Chromosomes, Flank (surface region), Entire bony skeleton, Bone Marrow and Body tissue. The associated genes with oxytetracycline are Polypeptides, Homologous Gene, Gene Clusters, Locus and CYCS gene. The related lipids are LH 1 and Lipid Peroxides. The related experimental models are Disease model.
To understand associated biological information of oxytetracycline, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
oxytetracycline is suspected in Infection, Helminthiasis, Nodule, Bacterial Infections, Yeast infection, pathologic fistula and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with oxytetracycline
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Disease model are used in the study 'A molecular ecological approach to the detection and designation of the etiological agents of a model polymicrobial disease.' (Antiabong JF et al., 2013).
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Authors | Title | Published | Journal | PubMed Link |
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Pietsch GS et al. | Antibiotic treatment and post-handling survival of reindeer calves in Alaska. | 1999 | J. Wildl. Dis. | pmid:10574533 |
Zinkl JG et al. | Treatment of captive giant Canada geese affected by avian cholera. | 1977 | J. Wildl. Dis. | pmid:916145 |
Taylor RE et al. | Attempts to control Whirling disease by continuous drug feeding. | 1973 | J. Wildl. Dis. | pmid:4784316 |
Yeruham I et al. | Parapox infection in a gazelle kid (Gazella gazella). | 1994 | J. Wildl. Dis. | pmid:8028113 |
Chong W et al. | Lack of bioequivalence of two oxytetracycline formulations in the rabbit. | 2002 | J. Vet. Sci. | pmid:14614269 |
Singh M et al. | Alteration of pharmacokinetics of oxytetracycline following oral administration of Piper longum in hens. | 2005 | J. Vet. Sci. | pmid:16131821 |
Nandi SK et al. | Efficacy of nano-hydroxyapatite prepared by an aqueous solution combustion technique in healing bone defects of goat. | 2008 | J. Vet. Sci. | pmid:18487940 |
Meijer LA et al. | Three phase elimination of oxytetracycline in veal calves; the presence of an extended terminal elimination phase. | 1993 | J. Vet. Pharmacol. Ther. | pmid:8345571 |
Christodoulopoulos G et al. | Tilmicosin administration to young lambs with respiratory infection: safety and efficacy considerations. | 2002 | J. Vet. Pharmacol. Ther. | pmid:12423233 |
Doi AM et al. | Pharmacokinetics of oxytetracycline in the red pacu (Colossoma brachypomum) following different routes of administration. | 1998 | J. Vet. Pharmacol. Ther. | pmid:9811436 |
Pijpers A et al. | In vitro activity of five tetracyclines and some other antimicrobial agents against four porcine respiratory tract pathogens. | 1989 | J. Vet. Pharmacol. Ther. | pmid:2810475 |
Mayeaux MH and Winston GW | Antibiotic effects on cytochromes P450 content and mixed-function oxygenase (MFO) activities in the American alligator, Alligator mississippiensis. | 1998 | J. Vet. Pharmacol. Ther. | pmid:9731949 |
Clarke CR et al. | Pharmacokinetics of two long-acting oxytetracycline products administered subcutaneously and intramuscularly. | 1999 | J. Vet. Pharmacol. Ther. | pmid:10211720 |
Banting AD et al. | A comparative study of serum kinetics of oxytetracycline in pigs and calves following intramuscular administration. | 1985 | J. Vet. Pharmacol. Ther. | pmid:4094034 |
Serrano JM et al. | Biliary elimination kinetics and tissue concentrations of oxytetracycline after intravenous administration in hens. | 1999 | J. Vet. Pharmacol. Ther. | pmid:10372599 |
Xia WJ et al. | Comparison of pharmacokinetic parameters for two oxytetracycline preparations in pigs. | 1983 | J. Vet. Pharmacol. Ther. | pmid:6887337 |
Kumar R and Malik JK | Influence of experimentally induced theileriosis (Theileria annulata) on the pharmacokinetics of a long-acting formulation of oxytetracycline (OTC-LA) in calves. | 1999 | J. Vet. Pharmacol. Ther. | pmid:10597536 |
Nouws JF et al. | Age-dependent pharmacokinetics of oxytetracycline in ruminants. | 1983 | J. Vet. Pharmacol. Ther. | pmid:6854733 |
Grondel JL et al. | Comparative pharmacokinetics of oxytetracycline in rainbow trout (Salmo gairdneri) and African catfish (Clarias gariepinus). | 1989 | J. Vet. Pharmacol. Ther. | pmid:2746722 |
Davies CP and Webster AJ | The effects of a beta 2-agonist (clenbuterol), and anti-bacterial drugs (trimethoprim with sulphadiazine; oxytetracycline) on calf mucociliary clearance. | 1989 | J. Vet. Pharmacol. Ther. | pmid:2746727 |
Pijpers A et al. | The pharmacokinetics of oxytetracycline following intravenous administration in healthy and diseased pigs. | 1990 | J. Vet. Pharmacol. Ther. | pmid:2231874 |
Roncada P et al. | Pharmacokinetics and residual behaviour in milk of oxytetracycline in cows following administration of uterine pessaries. | 2000 | J. Vet. Pharmacol. Ther. | pmid:11107001 |
Chiayvareesajja S et al. | The complete analysis of oxytetracycline pharmacokinetics in farmed Pacific white shrimp (Litopenaeus vannamei). | 2006 | J. Vet. Pharmacol. Ther. | pmid:16958786 |
Craigmill AL et al. | Serum pharmacokinetics of oxytetracycline in sheep and calves and tissue residues in sheep following a single intramuscular injection of a long-acting preparation. | 2000 | J. Vet. Pharmacol. Ther. | pmid:11168911 |
Dowling PM and Russell AM | Pharmacokinetics of a long-acting oxytetracycline-polyethylene glycol formulation in horses. | 2000 | J. Vet. Pharmacol. Ther. | pmid:10849256 |
Dieste-Pérez L et al. | Studies on a suitable antibiotic therapy for treating swine brucellosis. | 2015 | J. Vet. Pharmacol. Ther. | pmid:25413993 |
El Korchi G et al. | Disposition of oxytetracycline in pigs after i.m. administration of two long-acting formulations. | 2001 | J. Vet. Pharmacol. Ther. | pmid:11555179 |
Ball HJ and McCaughey WJ | Combined intramuscular oxytetracycline and oral tiamulin treatment of sheep in the elimination of urogenital ureaplasmas. | 1986 | J. Vet. Pharmacol. Ther. | pmid:3701912 |
Payne MA et al. | Serum pharmacokinetics and tissue and milk residues of oxytetracycline in goats following a single intramuscular injection of a long-acting preparation and milk residues following a single subcutaneous injection. | 2002 | J. Vet. Pharmacol. Ther. | pmid:11874523 |
Coetzee JF et al. | Flow cytometric evaluation of selected antimicrobial efficacy for clearance of Anaplasma marginale in short-term erythrocyte cultures. | 2006 | J. Vet. Pharmacol. Ther. | pmid:16669861 |
Meiszberg A et al. | Detection of ceftiofur and oxytetracycline in oral fluids of swine with a pen-side competitive ELISA test after intramuscular injection. | 2011 | J. Vet. Pharmacol. Ther. | pmid:21906083 |
Schrickx J and Fink-Gremmels J | P-glycoprotein-mediated transport of oxytetracycline in the Caco-2 cell model. | 2007 | J. Vet. Pharmacol. Ther. | pmid:17217397 |
Lees P et al. | Disposition of oxytetracycline in pigs after i.m. administration of two long-acting formulations. | 2002 | J. Vet. Pharmacol. Ther. | pmid:12081620 |
Ei Korchi G et al. | Disposition of oxytetracycline in pigs after i.m. administration of two long-acting formulations. | 2002 | J. Vet. Pharmacol. Ther. | pmid:12213121 |
Bengtsson B et al. | Penetration of oxytetracycline into tissue-cages in calves. | 1986 | J. Vet. Pharmacol. Ther. | pmid:3701918 |
Watson AD | Bioavailability and bioinequivalence of drug formulations in small animals. | 1992 | J. Vet. Pharmacol. Ther. | pmid:1433477 |
Bengtsson B et al. | Mathematical description of the concentration of oxytetracycline and penicillin-G in tissue cages in calves as related to the serum concentration. | 1992 | J. Vet. Pharmacol. Ther. | pmid:1433482 |
Bengtsson B et al. | Concentrations of sulphadimidine, oxytetracycline and penicillin G in serum, synovial fluid and tissue cage fluid after parenteral administration to calves. | 1989 | J. Vet. Pharmacol. Ther. | pmid:2704059 |
Furrow RD et al. | Characterization of a Pasteurella multocida (serotype B) bovine pneumonic pasteurellosis model and the effect of antimicrobials during peracute infection. | 1986 | J. Vet. Pharmacol. Ther. | pmid:3761417 |
Schifferli D et al. | Pharmacokinetics of oxytetracycline and therapeutic implications in veal calves. | 1982 | J. Vet. Pharmacol. Ther. | pmid:7183793 |
Gajda A et al. | Correlation between oral fluid and plasma oxytetracycline concentrations after intramuscular administration in pigs. | 2017 | J. Vet. Pharmacol. Ther. | pmid:28456999 |
Ziv G et al. | Distribution of penicillin G, dihydrostreptomycin, oxytetracycline, and chloramphenicol in serum and subcutaneous chamber fluid. | 1982 | J. Vet. Pharmacol. Ther. | pmid:6178837 |
Kumar R and Malik JK | Influence of endotoxin on the disposition kinetics and dosage regimens of oxytetracycline in calves. | 2003 | J. Vet. Pharmacol. Ther. | pmid:12755898 |
Nolan MW et al. | Pharmacokinetics of oxytetracycline in the American horseshoe crab, Limulus polyphemus. | 2007 | J. Vet. Pharmacol. Ther. | pmid:17803738 |
Dorey L et al. | What is the true in vitro potency of oxytetracycline for the pig pneumonia pathogens Actinobacillus pleuropneumoniae and Pasteurella multocida? | 2017 | J. Vet. Pharmacol. Ther. | pmid:28101885 |
Dorey L et al. | Pharmacokinetic/pharmacodynamic integration and modelling of oxytetracycline for the porcine pneumonia pathogens Actinobacillus pleuropneumoniae and Pasteurella multocida. | 2017 | J. Vet. Pharmacol. Ther. | pmid:28090673 |
Review of the 1993 Veterinary Drug Bioequivalence Workshop, held on March 29-31, 1993, in Rockville, Maryland. | 1994 | J. Vet. Pharmacol. Ther. | pmid:7913728 | |
Craigmill AL | A physiologically based pharmacokinetic model for oxytetracycline residues in sheep. | 2003 | J. Vet. Pharmacol. Ther. | pmid:12603776 |
Tell LA et al. | In vivo release of oxytetracycline from a biodegradable controlled-release gel injected subcutaneously in Japanese quail (Coturnix coturnix japonica). | 2003 | J. Vet. Pharmacol. Ther. | pmid:12887604 |
Oduye OO et al. | Serum antibiotic concentration and bovine skin susceptibility to infection by Dermatophilus congolensis. | 1987 | J. Vet. Pharmacol. Ther. | pmid:3612944 |
de Laistre Banting A and Fanneau de la Horie GC | Subcutaneous and intramuscular injection of oxytetracycline in calves: comparison of serum concentration and local tolerance. | 1987 | J. Vet. Pharmacol. Ther. | pmid:3612949 |
Depelchin BO et al. | Antipyrine disposition in calves. I. Effects of some drugs. | 1987 | J. Vet. Pharmacol. Ther. | pmid:3586123 |
Burrows GE et al. | Comparative pharmacokinetics of gentamicin, neomycin and oxytetracycline in newborn calves. | 1987 | J. Vet. Pharmacol. Ther. | pmid:3586124 |
Schoevers EJ et al. | An image analysis system: an objective and accurate alternative for reading the agar diffusion test. | 1994 | J. Vet. Pharmacol. Ther. | pmid:8196092 |
Deleforge J et al. | A field evaluation of the efficacy of tolfenamic acid and oxytetracycline in the treatment of bovine respiratory disease. | 1994 | J. Vet. Pharmacol. Ther. | pmid:8196093 |
McLelland DJ et al. | Single-dose pharmacokinetics of oxytetracycline and penicillin G in tammar wallabies (Macropus eugenii). | 2011 | J. Vet. Pharmacol. Ther. | pmid:21395607 |
Bimazubute M et al. | Penetration of oxytetracycline into the nasal secretions and relationship between nasal secretions and plasma oxytetracycline concentrations after oral and intramuscular administration in healthy pigs. | 2011 | J. Vet. Pharmacol. Ther. | pmid:21395609 |
Osofsky A et al. | Investigation of Japanese quail (Coturnix japonica) as a pharmacokinetic model for cockatiels (Nymphicus hollandicus) and Poicephalus parrots via comparison of the pharmacokinetics of a single intravenous injection of oxytetracycline hydrochloride. | 2005 | J. Vet. Pharmacol. Ther. | pmid:16343282 |
Black WD et al. | Pharmacokinetic and tissue distribution study of oxytetracycline in rainbow trout following bolus intravenous administration. | 1991 | J. Vet. Pharmacol. Ther. | pmid:1774812 |
Bengtsson B et al. | Distribution of oxytetracycline to tissue cages and granuloma pouches in calves and effect of acute inflammation on distribution to tissue cages. | 1991 | J. Vet. Pharmacol. Ther. | pmid:1774815 |
Cooke RG et al. | Bioavailability of oxytetracycline dihydrate tablets in dogs. | 1981 | J. Vet. Pharmacol. Ther. | pmid:7349318 |
Brentnall C et al. | Influence of oxytetracycline on carprofen pharmacodynamics and pharmacokinetics in calves. | 2013 | J. Vet. Pharmacol. Ther. | pmid:22913421 |
Kilroy CR et al. | Chlortetracycline in swine--bioavailability and pharmacokinetics in fasted and fed pigs. | 1990 | J. Vet. Pharmacol. Ther. | pmid:2319636 |
Brown MP et al. | Oxytetracycline hydrochloride in the horse: serum, synovial, peritoneal and urine concentrations after single dose intravenous administration. | 1981 | J. Vet. Pharmacol. Ther. | pmid:7349322 |
Paschoal JA et al. | Depletion study and estimation of the withdrawal period for oxytetracycline in tilapia cultured in Brazil. | 2012 | J. Vet. Pharmacol. Ther. | pmid:21470247 |
Elsheikh HA et al. | Comparative pharmacokinetics of ampicillin trihydrate, gentamicin sulphate and oxytetracycline hydrochloride in Nubian goats and desert sheep. | 1997 | J. Vet. Pharmacol. Ther. | pmid:9280365 |
Feng Q et al. | Pharmacokinetics of oxytetracycline in hemolymph from the Chinese mitten crab, Eriocheir sinensis. | 2011 | J. Vet. Pharmacol. Ther. | pmid:21219344 |
Craigmill AL et al. | Meta-analysis of pharmacokinetic data of veterinary drugs using the Food Animal Residue Avoidance Databank: oxytetracycline and procaine penicillin G. | 2004 | J. Vet. Pharmacol. Ther. | pmid:15500573 |
Haigh JC et al. | Pharmacokinetics of long-acting oxytetracycline in fallow deer (Dama dama). | 1997 | J. Vet. Pharmacol. Ther. | pmid:9185093 |
Fletouris DJ and Papapanagiotou EP | Tissue residue depletion of oxytetracycline after repeated intramuscular administration of Oxysentin 100 in sheep. | 2009 | J. Vet. Pharmacol. Ther. | pmid:19161456 |
George LW et al. | Distribution of oxytetracycline into ocular tissues and tears of calves. | 1985 | J. Vet. Pharmacol. Ther. | pmid:3989900 |
George LW and Smith JA | Treatment of Moraxella bovis infections in calves using a long-acting oxytetracycline formulation. | 1985 | J. Vet. Pharmacol. Ther. | pmid:3989901 |
Papich MG et al. | Pharmacokinetics of oxytetracycline administered intravenously to 4 to 5-day-old foals. | 1995 | J. Vet. Pharmacol. Ther. | pmid:8587157 |
Baxter P and McKellar QA | Distribution of oxytetracycline in normal and diseased ovine lung tissue. | 1990 | J. Vet. Pharmacol. Ther. | pmid:2287036 |
Banting AL and Baggot JD | Comparison of the pharmacokinetics and local tolerance of three injectable oxytetracycline formulations in pigs. | 1996 | J. Vet. Pharmacol. Ther. | pmid:8992026 |
Escudero E et al. | The pharmacokinetics of a long-acting formulation of oxytetracycline in sheep and goats. | 1996 | J. Vet. Pharmacol. Ther. | pmid:8992031 |
Grave K et al. | Comparison in prescribing patterns of antibacterial drugs in salmonid farming in Norway during the periods 1980-1988 and 1989-1994. | 1996 | J. Vet. Pharmacol. Ther. | pmid:8803876 |
Poapolathep A et al. | Muscle tissue kinetics of oxytetracycline following intramuscular and oral administration at two dosages to giant freshwater shrimp (Macrobrachium rosenbergii). | 2008 | J. Vet. Pharmacol. Ther. | pmid:19000273 |
Nielsen P and Gyrd-Hansen N | Bioavailability of oxytetracycline, tetracycline and chlortetracycline after oral administration to fed and fasted pigs. | 1996 | J. Vet. Pharmacol. Ther. | pmid:8866460 |
Poapolathep S et al. | Disposition of a long-acting oxytetracycline formulation in Thai swamp buffaloes (Bubalus bubalis). | 2017 | J. Vet. Pharmacol. Ther. | pmid:27597645 |
Lees P et al. | Pharmacokinetic-pharmacodynamic integration and modelling of oxytetracycline for the calf pathogens Mannheimia haemolytica and Pasteurella multocida. | 2018 | J. Vet. Pharmacol. Ther. | pmid:28736817 |
Burrows GE et al. | Chloramphenicol, lincomycin and oxytetracycline disposition in calves with experimental pneumonic pasteurellosis. | 1986 | J. Vet. Pharmacol. Ther. | pmid:3723664 |
Moreno L et al. | Pharmacokinetics of oxytetracycline after intravenous administration at two dose levels to hens. | 1996 | J. Vet. Pharmacol. Ther. | pmid:8971681 |
Ho SP et al. | Antibacterial effect of chloramphenicol, thiamphenicol and florfenicol against aquatic animal bacteria. | 2000 | J. Vet. Med. Sci. | pmid:10852395 |
Kim S et al. | Application of a solid-phase fluorescence immunoassay to determine oxytetracycline and tetracycline residues in tissue of olive flounder (Paralichthys olivaceus). | 2006 | J. Vet. Med. Sci. | pmid:17146190 |
Ishihara K et al. | The dynamics of antimicrobial-resistant Campylobacter jejuni on Japanese broiler farms. | 2006 | J. Vet. Med. Sci. | pmid:16757899 |
Matayoshi M et al. | Resistance phenotypes and genotypes among multiple-antimicrobial-resistant Salmonella enterica subspecies enterica serovar Choleraesuis strains isolated between 2008 and 2012 from slaughter pigs in Okinawa Prefecture, Japan. | 2015 | J. Vet. Med. Sci. | pmid:25715779 |
Usui M et al. | Antimicrobial susceptibility of indicator bacteria isolated from chickens in Southeast Asian countries (Vietnam, Indonesia and Thailand). | 2014 | J. Vet. Med. Sci. | pmid:24476850 |
Kaya O et al. | Isolation of Dermatophilus congolensis from a cat. | 2000 | J. Vet. Med. B Infect. Dis. Vet. Public Health | pmid:10763386 |
German AJ et al. | Comparison of direct and indirect tests for small intestinal bacterial overgrowth and antibiotic-responsive diarrhea in dogs. | 2003 Jan-Feb | J. Vet. Intern. Med. | pmid:12564725 |
Kaler J et al. | Randomized clinical trial of long-acting oxytetracycline, foot trimming, and flunixine meglumine on time to recovery in sheep with footrot. | 2010 Mar-Apr | J. Vet. Intern. Med. | pmid:20051002 |
Frazer ML | Lawsonia intracellularis infection in horses: 2005-2007. | 2008 Sep-Oct | J. Vet. Intern. Med. | pmid:18681919 |
Restifo MM et al. | Cavitary effusion associated with Anaplasma phagocytophilum infection in 2 equids. | 2015 Mar-Apr | J. Vet. Intern. Med. | pmid:25711458 |
Van Biervliet J et al. | Clinical signs, computed tomographic imaging, and management of chronic otitis media/interna in dairy calves. | 2004 Nov-Dec | J. Vet. Intern. Med. | pmid:15638279 |
Sweeney RW et al. | Hepatic failure in dairy cattle following mastitis or metritis. | 1988 Apr-Jun | J. Vet. Intern. Med. | pmid:3221362 |
Hulme-Moir KL et al. | Use of real-time quantitative polymerase chain reaction to monitor antibiotic therapy in a dog with naturally acquired Mycoplasma haemocanis infection. | 2010 | J. Vet. Diagn. Invest. | pmid:20622229 |
Soehnlen MK et al. | In vitro antimicrobial inhibition of Mycoplasma bovis isolates submitted to the Pennsylvania Animal Diagnostic Laboratory using flow cytometry and a broth microdilution method. | 2011 | J. Vet. Diagn. Invest. | pmid:21908288 |
Burrows GE and Ewing P | In vitro assessment of the efficacy of erythromycin in combination with oxytetracycline or spectinomycin against Pasteurella haemolytica. | 1989 | J. Vet. Diagn. Invest. | pmid:2535123 |
Antiabong JF et al. | A molecular ecological approach to the detection and designation of the etiological agents of a model polymicrobial disease. | 2013 | J. Vet. Diagn. Invest. | pmid:23780937 |
NESBIT RM et al. | Clinical experience with terramycin in treatment of refractory urinary tract infections. | 1951 | J. Urol. | pmid:14804793 |