oxytetracycline

oxytetracycline is a lipid of Polyketides (PK) class. Oxytetracycline is associated with abnormalities such as Infection, X-linked centronuclear myopathy, Bacterial Infections, Heart failure and Onchocerciasis. The involved functions are known as Anabolism, physiological aspects, Transcription, Genetic, Fermentation and Transcriptional Activation. Oxytetracycline often locates in Chromosomes, Flank (surface region), Entire bony skeleton, Bone Marrow and Body tissue. The associated genes with oxytetracycline are Polypeptides, Homologous Gene, Gene Clusters, Locus and CYCS gene. The related lipids are LH 1 and Lipid Peroxides. The related experimental models are Disease model.

Cross Reference

Introduction

To understand associated biological information of oxytetracycline, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with oxytetracycline?

oxytetracycline is suspected in Infection, Helminthiasis, Nodule, Bacterial Infections, Yeast infection, pathologic fistula and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with oxytetracycline

MeSH term MeSH ID Detail
Dental Caries D003731 6 associated lipids
Cattle Diseases D002418 24 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Body Weight D001835 333 associated lipids
Mandibular Diseases D008336 5 associated lipids
Foreign-Body Reaction D005549 10 associated lipids
Arthritis D001168 41 associated lipids
Fractures, Bone D050723 4 associated lipids
Abscess D000038 13 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Per page 10 20 50 100 | Total 137

PubChem Associated disorders and diseases

What pathways are associated with oxytetracycline

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with oxytetracycline?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with oxytetracycline?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with oxytetracycline?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with oxytetracycline?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with oxytetracycline?

Disease model

Disease model are used in the study 'A molecular ecological approach to the detection and designation of the etiological agents of a model polymicrobial disease.' (Antiabong JF et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with oxytetracycline

Download all related citations
Per page 10 20 50 100 | Total 5138
Authors Title Published Journal PubMed Link
Wang Y et al. Comparison of oxytetracycline degradation behavior in pig manure with different antibiotic addition methods. 2015 Environ Sci Pollut Res Int pmid:26278905
Alavi N et al. Assessment of oxytetracycline and tetracycline antibiotics in manure samples in different cities of Khuzestan Province, Iran. 2015 Environ Sci Pollut Res Int pmid:26165993
Shentu JL et al. Effect from low-level exposure of oxytetracycline on abundance of tetracycline resistance genes in arable soils. 2015 Environ Sci Pollut Res Int pmid:25925140
Kim SY et al. Occurrence and diversity of tetracycline resistance genes in the agricultural soils of South Korea. 2016 Environ Sci Pollut Res Int pmid:27638788
Domínguez C et al. Evaluation of antibiotic mobility in soil associated with swine-slurry soil amendment under cropping conditions. 2014 Environ Sci Pollut Res Int pmid:24938815
Fernández-Calviño D et al. Kinetics of tetracycline, oxytetracycline, and chlortetracycline adsorption and desorption on two acid soils. 2015 Environ Sci Pollut Res Int pmid:25081007
Castro-Gutiérrez V et al. Impact of oxytetracycline and bacterial bioaugmentation on the efficiency and microbial community structure of a pesticide-degrading biomixture. 2018 Environ Sci Pollut Res Int pmid:29442313
Gao M et al. Removal mechanism of di-n-butyl phthalate and oxytetracycline from aqueous solutions by nano-manganese dioxide modified biochar. 2018 Environ Sci Pollut Res Int pmid:29290063
Nakano T et al. Effect of excessive doses of oxytetracycline on stress-related biomarker expression in coho salmon. 2018 Environ Sci Pollut Res Int pmid:26111749
Wang J et al. Effects of thermophilic composting on oxytetracycline, sulfamethazine, and their corresponding resistance genes in swine manure. 2015 Environ Sci Process Impacts pmid:26216606
Wang X et al. Effects of oxytetracycline on archaeal community, and tetracycline resistance genes in anaerobic co-digestion of pig manure and wheat straw. 2016 Environ Technol pmid:27115735
Zheng D et al. Performance comparison of biofilm and suspended sludge from a sequencing batch biofilm reactor treating mariculture wastewater under oxytetracycline stress. 2016 Environ Technol pmid:26854088
Çelebi H et al. Removals of non-analogous OTC and BaP in AMCBR with and without primary substrate. 2016 Environ Technol pmid:26670775
Ma W et al. Treatment of antibiotics wastewater utilizing successive hydrolysis, denitrification and nitrification. 2002 Environ Technol pmid:12118620
Akyol C et al. Acidification of non-medicated and oxytetracycline-medicated cattle manures during anaerobic digestion. 2014 Sep-Oct Environ Technol pmid:25145191
Giordano R et al. Effect of a high dose of three antibiotics on the reproduction of a parthenogenetic strain of Folsomia candida (Isotomidae: Collembola). 2010 Environ. Entomol. pmid:22127168
Kleinstreuer NC et al. Environmental impact on vascular development predicted by high-throughput screening. 2011 Environ. Health Perspect. pmid:21788198
Liu J et al. Soil-borne reservoirs of antibiotic-resistant bacteria are established following therapeutic treatment of dairy calves. 2016 Environ. Microbiol. pmid:26486254
Jin X et al. The effect of Cu(2+) chelation on the direct photolysis of oxytetracycline: A study assisted by spectroscopy analysis and DFT calculation. 2016 Environ. Pollut. pmid:27155101
Leal JF et al. Use of sunlight to degrade oxytetracycline in marine aquaculture's waters. 2016 Environ. Pollut. pmid:27049790
Kay P et al. A lysimeter experiment to investigate the leaching of veterinary antibiotics through a clay soil and comparison with field data. 2005 Environ. Pollut. pmid:15589660
Kong WD et al. Uptake of oxytetracycline and its phytotoxicity to alfalfa (Medicago sativa L.). 2007 Environ. Pollut. pmid:17029682
Gomiero A and Viarengo A Effects of elevated temperature on the toxicity of copper and oxytetracycline in the marine model, Euplotes crassus: a climate change perspective. 2014 Environ. Pollut. pmid:25163430
Kong WD et al. The veterinary antibiotic oxytetracycline and Cu influence functional diversity of the soil microbial community. 2006 Environ. Pollut. pmid:16413090
Chen C et al. Occurrence of antibiotics and antibiotic resistances in soils from wastewater irrigation areas in Beijing and Tianjin, China. 2014 Environ. Pollut. pmid:25016103
Brain RA et al. Effects of a mixture of tetracyclines to Lemna gibba and Myriophyllum sibiricum evaluated in aquatic microcosms. 2005 Environ. Pollut. pmid:15996801
Zhang Y et al. Insights into aquatic toxicities of the antibiotics oxytetracycline and ciprofloxacin in the presence of metal: complexation versus mixture. 2012 Environ. Pollut. pmid:22475550
Wallace JS et al. Occurrence and transformation of veterinary antibiotics and antibiotic resistance genes in dairy manure treated by advanced anaerobic digestion and conventional treatment methods. 2018 Environ. Pollut. pmid:29455089
Chen F et al. Distribution and accumulation of endocrine-disrupting chemicals and pharmaceuticals in wastewater irrigated soils in Hebei, China. 2011 Environ. Pollut. pmid:21477905
Hanson ML et al. Field assessment of oxytetracycline exposure to the freshwater macrophytes Egeria densa Planch. and Ceratophyllum demersum L. 2006 Environ. Pollut. pmid:16253408
Duan M et al. Effects of biochar on reducing the abundance of oxytetracycline, antibiotic resistance genes, and human pathogenic bacteria in soil and lettuce. 2017 Environ. Pollut. pmid:28284554
Tian Z et al. Chronic impacts of oxytetracycline on mesophilic anaerobic digestion of excess sludge: Inhibition of hydrolytic acidification and enrichment of antibiotic resistome. 2018 Environ. Pollut. pmid:29449116
Zhou L et al. Environmental concentrations of antibiotics impair zebrafish gut health. 2018 Environ. Pollut. pmid:29291524
Leal JF et al. Antibacterial activity of oxytetracycline photoproducts in marine aquaculture's water. 2017 Environ. Pollut. pmid:27769773
Yang JF et al. Dissipation of oxytetracycline in soils under different redox conditions. 2009 Environ. Pollut. pmid:19467565
Zhang W et al. Accumulation of tetracycline resistance genes in aquatic biofilms due to periodic waste loadings from swine lagoons. 2009 Environ. Sci. Technol. pmid:19921873
Oleszczuk P et al. Adsorption and desorption of oxytetracycline and carbamazepine by multiwalled carbon nanotubes. 2009 Environ. Sci. Technol. pmid:20000507
Bui TX and Choi H Comment on "Adsorption and desorption of oxytetracycline and carbamazepine by multiwalled carbon nanotubes". 2010 Environ. Sci. Technol. pmid:20469851
Simon NS Loosely bound oxytetracycline in riverine sediments from two tributaries of the Chesapeake bay. 2005 Environ. Sci. Technol. pmid:15952351
Rosenblum ES et al. Effects of temperature on host-pathogen-drug interactions in red abalone, Haliotis rufescens, determined by 1H NMR metabolomics. 2006 Environ. Sci. Technol. pmid:17154019
Figueroa RA and MacKay AA Sorption of oxytetracycline to iron oxides and iron oxide-rich soils. 2005 Environ. Sci. Technol. pmid:16190225
Kulshrestha P et al. Investigating the molecular interactions of oxytetracycline in clay and organic matter: insights on factors affecting its mobility in soil. 2004 Environ. Sci. Technol. pmid:15352447
Rubert KF and Pedersen JA Kinetics of oxytetracycline reaction with a hydrous manganese oxide. 2006 Environ. Sci. Technol. pmid:17180969
Engemann CA et al. Fate of tetracycline resistance genes in aquatic systems: migration from the water column to peripheral biofilms. 2008 Environ. Sci. Technol. pmid:18754359
Knapp CW et al. Indirect evidence of transposon-mediated selection of antibiotic resistance genes in aquatic systems at low-level oxytetracycline exposures. 2008 Environ. Sci. Technol. pmid:18754392
Liu M et al. Abundance and distribution of tetracycline resistance genes and mobile elements in an oxytetracycline production wastewater treatment system. 2012 Environ. Sci. Technol. pmid:22709269
Aristilde L et al. Interactions of oxytetracycline with a smectite clay: a spectroscopic study with molecular simulations. 2010 Environ. Sci. Technol. pmid:20866047
Carrasquillo AJ et al. Sorption of ciprofloxacin and oxytetracycline zwitterions to soils and soil minerals: influence of compound structure. 2008 Environ. Sci. Technol. pmid:18983086
DeLorenzo ME et al. Exposure of the grass shrimp, Palaemonetes pugio, to antimicrobial compounds affects associated Vibrio bacterial density and development of antibiotic resistance. 2016 Environ. Toxicol. pmid:25348372
Rose PE and Pedersen JA Fate of oxytetracycline in streams receiving aquaculture discharges: model simulations. 2005 Environ. Toxicol. Chem. pmid:15683166
Peng FJ et al. Antibacterial activity of the soil-bound antimicrobials oxytetracycline and ofloxacin. 2014 Environ. Toxicol. Chem. pmid:24408539
ter Laak TL et al. The effect of pH and ionic strength on the sorption of sulfachloropyridazine, tylosin, and oxytetracycline to soil. 2006 Environ. Toxicol. Chem. pmid:16629129
ter Laak TL et al. Estimation of soil sorption coefficients of veterinary pharmaceuticals from soil properties. 2006 Environ. Toxicol. Chem. pmid:16629132
Zounková R et al. Complex evaluation of ecotoxicity and genotoxicity of antimicrobials oxytetracycline and flumequine used in aquaculture. 2011 Environ. Toxicol. Chem. pmid:21312248
Kay P et al. Fate of veterinary antibiotics in a macroporous tile drained clay soil. 2004 Environ. Toxicol. Chem. pmid:15180364
Li D et al. Determination and fate of oxytetracycline and related compounds in oxytetracycline production wastewater and the receiving river. 2008 Environ. Toxicol. Chem. pmid:18092864
Jones AD et al. Factors influencing the sorption of oxytetracycline to soils. 2005 Environ. Toxicol. Chem. pmid:15839547
Thiele-Bruhn S Microbial inhibition by pharmaceutical antibiotics in different soils--dose-response relations determined with the iron(III) reduction test. 2005 Environ. Toxicol. Chem. pmid:15839561
Goetsch HE et al. Oxytetracycline interactions at the soil-water interface: effects of environmental surfaces on natural transformation and growth inhibition of Azotobacter vinelandii. 2012 Environ. Toxicol. Chem. pmid:22821843
Uyaguari M et al. Acute effects of the antibiotic oxytetracycline on the bacterial community of the grass shrimp, Palaemonetes pugio. 2009 Environ. Toxicol. Chem. pmid:19400597
Gao M et al. Interactive effect of oxytetracycline and lead on soil enzymatic activity and microbial biomass. 2013 Environ. Toxicol. Pharmacol. pmid:23892283
Gao M et al. Combined effects of oxytetracycline and Pb on earthworm Eisenia fetida. 2014 Environ. Toxicol. Pharmacol. pmid:24607684
Wang C et al. The oxidative stress response of oxytetracycline in the ciliate Pseudocohnilembus persalinus. 2017 Environ. Toxicol. Pharmacol. pmid:28881225
Suga N et al. Risk assessment of oxytetracycline in water phase to major sediment bacterial community: a water-sediment microcosm study. 2013 Environ. Toxicol. Pharmacol. pmid:23619519
Slana M and Dolenc MS Environmental Risk Assessment of antimicrobials applied in veterinary medicine-A field study and laboratory approach. 2013 Environ. Toxicol. Pharmacol. pmid:23274419
Rodrigues S et al. Histological alterations in gills and liver of rainbow trout (Oncorhynchus mykiss) after exposure to the antibiotic oxytetracycline. 2017 Environ. Toxicol. Pharmacol. pmid:28599186
Oliveira R et al. Effects of oxytetracycline and amoxicillin on development and biomarkers activities of zebrafish (Danio rerio). 2013 Environ. Toxicol. Pharmacol. pmid:24008007
Gao M et al. Avoidance behavior of Eisenia fetida in oxytetracycline- and heavy metal-contaminated soils. 2016 Environ. Toxicol. Pharmacol. pmid:27665306
Mihciokur H and Oguz M Removal of oxytetracycline and determining its biosorption properties on aerobic granular sludge. 2016 Environ. Toxicol. Pharmacol. pmid:27485178
Tang Z et al. Improved oxytetracycline production in Streptomyces rimosus M4018 by metabolic engineering of the G6PDH gene in the pentose phosphate pathway. 2011 Enzyme Microb. Technol. pmid:22112266
Yu L et al. Oxytetracycline biosynthesis improvement in Streptomyces rimosus following duplication of minimal PKS genes. 2012 Enzyme Microb. Technol. pmid:22500899
Carević O and Cerlek N The inhibitory effect of oxytetracycline on the glucose degradation in human erythrocytes. 1971 Enzymologia pmid:4940282
Sanciu G et al. Outbreak of mastitis in sheep caused by multi-drug resistant Enterococcus faecalis in Sardinia, Italy. 2013 Epidemiol. Infect. pmid:22595402
Sasaki Y et al. Prevalence and antimicrobial susceptibility of Salmonella in Japanese broiler flocks. 2012 Epidemiol. Infect. pmid:22281015
Nijsten R et al. Resistance in faecal Escherichia coli isolated from pigfarmers and abattoir workers. 1994 Epidemiol. Infect. pmid:8062879
O'Connor AM et al. Verotoxins in commensal Escherichia coli in cattle: the effect of injectable subcutaneous oxytetracycline in addition to in-feed chlortetracycline on prevalence. 2004 Epidemiol. Infect. pmid:14979593
Pilsworth RC and Head MJ A study of ten cases of focal peritarsal infection as a cause of severe lameness in the thoroughbred racehorse: clinical signs, differential diagnosis, treatment and outcome. 2001 Equine Vet. J. pmid:11469769
Horspool LJ and McKellar QA Disposition of oxytetracycline in horses, ponies and donkeys after intravenous administration. 1990 Equine Vet. J. pmid:2209525
Sampieri F et al. Tetracycline therapy of Lawsonia intracellularis enteropathy in foals. 2006 Equine Vet. J. pmid:16411593
HAENEL H and GERRIETS E [Feeding of chickens with tetracycline in nutritive, therapeutic and overdosage quantities]. 1961 Ernahrungsforsch Ber Mitt pmid:13710402
Ruth M et al. A clinical comparison of hydrocortisone butyrate with oxytetracycline/hydrocortisone acetate-polymyxin B in the local treatment of acute external otitis. 1990 Eur Arch Otorhinolaryngol pmid:2156538
Yildirim E et al. Rapid pleurodesis in symptomatic malignant pleural effusion. 2005 Eur J Cardiothorac Surg pmid:15621465
Talevi A et al. Prediction of drug intestinal absorption by new linear and non-linear QSPR. 2011 Eur J Med Chem pmid:21112128
Machán V et al. SORB-GEL method of analysis of 99mTc-labelled compounds. 1980 Eur J Nucl Med pmid:7379804
Liu SS et al. Continuous forces are more effective than intermittent forces in expanding sutures. 2010 Eur J Orthod pmid:20053718
Chetoni P et al. Silicone rubber/hydrogel composite ophthalmic inserts: preparation and preliminary in vitro/in vivo evaluation. 1998 Eur J Pharm Biopharm pmid:9700030
de Jonge HR and Hülsmann WC Inhibition of mitochondrial-protein synthesis in rat small-intestinal epithelium. 1973 Eur. J. Biochem. pmid:4347093
Hobson D et al. Evaluation of a seven day course of oxytetracycline in women with chlamydial cervicitis. 1986 Eur. J. Clin. Microbiol. pmid:3780714
Ridgway GL et al. The activity of ciprofloxacin and other 4-quinolones against Chlamydia trachomatis and Mycoplasmas in vitro. 1984 Eur. J. Clin. Microbiol. pmid:6237903
Czeizel AE and Rockenbauer M A population-based case-control teratologic study of oral oxytetracycline treatment during pregnancy. 2000 Eur. J. Obstet. Gynecol. Reprod. Biol. pmid:10659913
Hobusch D and Putzke HP [Effect of oxytetracycline (OTC) on the secretion kinetics of the rat exocrine pancreas]. 1971 Exp Pathol (Jena) pmid:4335637
METZGER JF et al. Antibiotics in tissue culture. 1954 Exp. Cell Res. pmid:13173487
Chandler HL et al. The role of the slug transcription factor in cell migration during corneal re-epithelialization in the dog. 2007 Exp. Eye Res. pmid:17196588
Terzian LA et al. The sporogonous of Plasmodium vivax in Anopheles mosquitoes as a system for evaluating the prophylactic and curative capabilities of potential antimalarial compounds. 1968 Exp. Parasitol. pmid:4876903
Todorovic RA et al. Babesia bigemina, Babesia argentina, and Anaplasma marginale: Coinfectious immunity in bovines. 1975 Exp. Parasitol. pmid:1123013
Speybroeck N et al. Titrating Theileria parva: single stocks against combination of stocks. 2008 Exp. Parasitol. pmid:18155195
Graf E and Benz G Toxicity of streptomycin and terramycin, and influence on growth and developmental time of Drosophila melanogaster. 1970 Experientia pmid:5492218
Lal OP Synergism of terramycin to inhibit the reproductivity of aphis fabae scop. 1972 Experientia pmid:5045184
Katsuragi T and Suzuki T Ouabain-induced release of extraneuronal catecholamine in the isolated guinea-pig vas deferens. 1976 Experientia pmid:950020
Brzin B The effect of penicillin on Pasteurella pseudotuberculosis morphology. 1964 Experientia pmid:5853677