oxytetracycline

oxytetracycline is a lipid of Polyketides (PK) class. Oxytetracycline is associated with abnormalities such as Infection, X-linked centronuclear myopathy, Bacterial Infections, Heart failure and Onchocerciasis. The involved functions are known as Anabolism, physiological aspects, Transcription, Genetic, Fermentation and Transcriptional Activation. Oxytetracycline often locates in Chromosomes, Flank (surface region), Entire bony skeleton, Bone Marrow and Body tissue. The associated genes with oxytetracycline are Polypeptides, Homologous Gene, Gene Clusters, Locus and CYCS gene. The related lipids are LH 1 and Lipid Peroxides. The related experimental models are Disease model.

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Introduction

To understand associated biological information of oxytetracycline, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with oxytetracycline?

oxytetracycline is suspected in Infection, Helminthiasis, Nodule, Bacterial Infections, Yeast infection, pathologic fistula and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with oxytetracycline

MeSH term MeSH ID Detail
Dental Caries D003731 6 associated lipids
Cattle Diseases D002418 24 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Body Weight D001835 333 associated lipids
Mandibular Diseases D008336 5 associated lipids
Foreign-Body Reaction D005549 10 associated lipids
Arthritis D001168 41 associated lipids
Fractures, Bone D050723 4 associated lipids
Abscess D000038 13 associated lipids
Acute Kidney Injury D058186 34 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with oxytetracycline

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with oxytetracycline?

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What functions are associated with oxytetracycline?


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What lipids are associated with oxytetracycline?

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What genes are associated with oxytetracycline?

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What common seen animal models are associated with oxytetracycline?

Disease model

Disease model are used in the study 'A molecular ecological approach to the detection and designation of the etiological agents of a model polymicrobial disease.' (Antiabong JF et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with oxytetracycline

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Authors Title Published Journal PubMed Link
Magonigle RA and Newby TJ Response of cattle upon reexposure to Anaplasma marginale after elimination of chronic carrier infections. 1984 Am. J. Vet. Res. pmid:6731981
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Wooley RE et al. Inhibitory effects of combinations of oxytetracycline, dimethyl sulfoxide, and EDTA-tromethamine on Escherichia coli. 1981 Am. J. Vet. Res. pmid:6802044
Hatch RC et al. Induced acute aflatoxicosis in goats: treatment with activated charcoal or dual combinations of oxytetracycline, stanozolol, and activated charcoal. 1982 Am. J. Vet. Res. pmid:6803625
Toutain PL and Raynaud JP Pharmacokinetics of oxytetracycline in young cattle: comparison of conventional vs long-acting formulations. 1983 Am. J. Vet. Res. pmid:6881660
Ames TR et al. Oxytetracycline concentrations in healthy and diseased calves. 1983 Am. J. Vet. Res. pmid:6881673
Kuttler KL and Simpson JE Relative efficacy of two oxytetracycline formulations and doxycycline in the treatment of acute anaplasmosis in splenectomized calves. 1978 Am. J. Vet. Res. pmid:629473
Clark JD et al. Effects of various treatments on induced chronic aflatoxicosis in rabbits. 1982 Am. J. Vet. Res. pmid:6807140
Wooley RE et al. Antibacterial action of combinations of oxytetracycline, dimethyl sulfoxide, and EDTA-tromethamine on Proteus, Salmonella, and Aeromonas. 1982 Am. J. Vet. Res. pmid:6807142
Latour PB and Barnum DA Use of ducks as a model to study the effect of antibiotics in feed on the fecal shedding of Salmonella. 1981 Am. J. Vet. Res. pmid:7041704
George LW et al. Effectiveness of two benzathine cloxacillin formulations for treatment of naturally occurring infectious bovine keratoconjunctivitis. 1989 Am. J. Vet. Res. pmid:2774340
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Davis RW et al. The effects of an oxytetracycline preparation on the thyroid gland: a preliminary report. 1966 Am. J. Vet. Res. pmid:5913021
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Simpson CF Morphologic alterations of Anaplasma marginale in calves after treatment with oxytetracycline. 1975 Am. J. Vet. Res. pmid:1190584
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BARNES LE Oxytetracycline in bovine mastitis. I. Treatment of mastitis. 1955 Am. J. Vet. Res. pmid:13238740
Kaneene JB et al. Drug residues in milk after intrauterine injection of oxytetracycline, lincomycin-spectinomycin, and povidone-iodine in cows with metritis. 1986 Am. J. Vet. Res. pmid:2942064
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Pindak FF et al. Incidence and distribution of spirochetes in the digestive tract of dogs. 1965 Am. J. Vet. Res. pmid:5882556
Guerra MA and Nicoletti P Comparison of the susceptibility of Brucella abortus isolates obtained before and after cows were treated with oxytetracycline and streptomycin. 1986 Am. J. Vet. Res. pmid:3099613
Bretzlaff KN et al. Distribution of oxytetracycline in the genital tract of cows. 1982 Am. J. Vet. Res. pmid:7091807
Lincoln SD et al. Bovine anaplasmosis: clinical, hematologic, and serologic manifestations in cows given a long-acting oxytetracycline formulation in the prepatent period. 1982 Am. J. Vet. Res. pmid:7103219
Lubbers BV et al. Effects of two simulated oxytetracycline dosing regimens on horizontal transfer of antimicrobial resistance plasmids in an in vitro pharmacodynamic model. 2011 Am. J. Vet. Res. pmid:21728847
Sarmiento JI and Moon HW Postweaning diarrhea in swine: effects of oxytetracycline on enterotoxigenic Escherichia coli infection. 1988 Am. J. Vet. Res. pmid:3048158
Arnoczky SP et al. In vitro effects of oxytetracycline on matrix metalloproteinase-1 mRNA expression and on collagen gel contraction by cultured myofibroblasts obtained from the accessory ligament of foals. 2004 Am. J. Vet. Res. pmid:15077693
Palmer JE et al. Effect of treatment with oxytetracycline during the acute stages of experimentally induced equine ehrlichial colitis in ponies. 1992 Am. J. Vet. Res. pmid:1476312
Oukessou M et al. Pharmacokinetics and local tolerance of a long-acting oxytetracycline formulation in camels. 1992 Am. J. Vet. Res. pmid:1416372
Magonigle RA and Newby TJ Elimination of naturally acquired chronic Anaplasma marginale infections with a long-acting oxytetracycline injectable. 1982 Am. J. Vet. Res. pmid:7165161
Kuttler KL Efficacy of oxytetracycline and a dithiosemicarbazone in the treatment of bovine anaplasmosis. 1971 Am. J. Vet. Res. pmid:5094519
Riner JL et al. Influence of density and location on degradation of sustained-release boluses given to cattle. 1982 Am. J. Vet. Res. pmid:7181203
Hatch RC et al. Effect of antibacterials, anabolic steroid, and diethyldithiocarbamate on induced acute aflatoxicosis in goats. 1982 Am. J. Vet. Res. pmid:6280533
Gross DR et al. Cardiovascular effects of intravenous administration of propylene glycol and of oxytetracycline in propylene glycol in calves. 1979 Am. J. Vet. Res. pmid:475130
Gross DR et al. Adverse cardiovascular effects of oxytetracycline preparations and vehicles in intact awake calves. 1981 Am. J. Vet. Res. pmid:7294473
Abbitt B et al. Effect of dihydrostreptomycin or oxytetracycline on reproductive capacity of bulls. 1984 Am. J. Vet. Res. pmid:6084431
Gyles C et al. In vivo transfer of an Escherichia coli enterotoxin plasmid possessing genes for drug resistance. 1978 Am. J. Vet. Res. pmid:358869
byford RL et al. Chemoprophylaxis of vector-borne anaplasmosis with sustained-release boluses. 1981 Am. J. Vet. Res. pmid:7340579
McElroy DE et al. Pharmacokinetics of oxytetracycline hydrochloride in rabbits. 1987 Am. J. Vet. Res. pmid:3631718
Larson VL and Stowe CM Plasma and tissue concentrations of oxytetracycline in the horse after intravenous administration. 1981 Am. J. Vet. Res. pmid:7340586
Fugler LA et al. Plasma matrix metalloproteinase activity in horses after intravenous infusion of lipopolysaccharide and treatment with matrix metalloproteinase inhibitors. 2013 Am. J. Vet. Res. pmid:23438126
BARNES LE Oxytetracycline in bovine mastitis. II. Milk levels following local and parenteral administration. 1956 Am. J. Vet. Res. pmid:13283224
Fielding CL et al. Evaluation of potential predictor variables for PCR assay diagnosis of Anaplasma phagocytophilum infection in equids in Northern California. 2018 Am. J. Vet. Res. pmid:30085857
Edmondson AJ et al. Survival analysis for evaluation of corneal ulcer healing times in calves with naturally acquired infectious bovine keratoconjunctivitis. 1989 Am. J. Vet. Res. pmid:2764337
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Ames TR and Patterson EB Oxytetracycline concentrations in plasma and lung of healthy and pneumonic calves, using two oxytetracycline preparations. 1985 Am. J. Vet. Res. pmid:3909863
Moats WA et al. Comparison of a radioimmunoassay (Charm II) test with high-performance liquid chromatography for detection of oxytetracycline residues in milk samples from lactating cattle. 1995 Am. J. Vet. Res. pmid:7653890
Simpson CF Morphologic alteration of Paranaplasma caudata following treatment of calves with oxytetracycline. 1977 Am. J. Vet. Res. pmid:931133
Wintz LR et al. Age-dependent effects of systemic administration of oxytetracycline on the viscoelastic properties of rat tail tendons as a mechanistic basis for pharmacological treatment of flexural limb deformities in foals. 2012 Am. J. Vet. Res. pmid:23176422
Button C and Mülders MS Effects of oxytetracycline in propylene glycol, oxytetracycline in saline solution, and propylene glycol alone on blood ionized calcium and plasma total calcium in sheep. 1984 Am. J. Vet. Res. pmid:6476580
Paulsen DB et al. Use of an indwelling bronchial catheter model of bovine pneumonic pasteurellosis for evaluation of therapeutic efficacy of various compounds. 1992 Am. J. Vet. Res. pmid:1524292
Milward FW et al. Effectiveness of various therapeutic regimens for bovine brucellosis. 1984 Am. J. Vet. Res. pmid:6208830
Fecteau KA and Eiler H Evaluation of injections of collagenase and oxytetracycline via the umbilical artery as treatment for retained placenta in cattle. 1996 Am. J. Vet. Res. pmid:8712518
Myers MJ et al. In vitro modulation of bovine blood neutrophils and mononuclear cells by oxytetracycline. 1995 Am. J. Vet. Res. pmid:8533970
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BUMBALO TS et al. Pinworm infection (enterobiasis) in children; a comparative study of four oxyuricides. 1953 AMA Am J Dis Child pmid:13103773
BALER GR Oxytetracycline intramuscular in the treatment of early syphilis. 1956 AMA Arch Derm pmid:13312644
BAREFOOT SW Oxytetracycline hydrochloride-polymyxin B sulfate topical powder. 1959 AMA Arch Derm pmid:13636430
STRITZLER C and FRANK L Topical hydrocortisone-oxytetracycline therapy. 1955 AMA Arch Derm pmid:14375396
SNYDER W Terramycin therapy of eczema vaccinatum; report of a case. 1951 AMA Arch Derm Syphilol pmid:14867923
NIEDELMAN ML Molluscum contagiosum treated with oxytetracycline (terramycin). 1953 AMA Arch Derm Syphilol pmid:13007184
MOPPER C Terramycin therapy of molluscum contagiosum. 1952 AMA Arch Derm Syphilol pmid:14914183
TSCHAN DN and WRIGHT CS Safety of systemic oxytetracycline (terramycin) therapy following or with topical therapy. 1954 AMA Arch Derm Syphilol pmid:13147576
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WRIGHT CS and TSCHAN DN Local oxytetracycline (terramycin) therapy of skin infections. 1953 AMA Arch Derm Syphilol pmid:13029894
FERGUSON BC and TYLER MD Edema and hypoproteinemia following diarrhea associated with oxytetracycline therapy. 1954 AMA Arch Intern Med pmid:13196730
WOMACK CR et al. Terramycin therapy of urinary tract infections. 1952 AMA Arch Intern Med pmid:14884789
MAGILL GB and KILLOUGH JH Oxytetracycline-streptomycin therapy in brucellosis due to Brucella melitensis. 1953 AMA Arch Intern Med pmid:13016039
BATEMAN JC et al. Fatal complications of intensive antibiotic therapy in patients with neoplastic disease. 1952 AMA Arch Intern Med pmid:12996105
KNIGHT V et al. Terramycin in treatment of human brucellosis. 1951 AMA Arch Intern Med pmid:14829089
DI CAPRIO JM and RANTZ LA Effects of terramycin on the bacterial flora of the bowel in man. 1950 AMA Arch Intern Med pmid:14770585
MITSUI Y et al. Terramycin in the treatment of trachoma. 1951 AMA Arch Ophthalmol pmid:14868042
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FOLBRE TW et al. Rhinoscleroma successfully treated with oxytetracycline (terramycin). 1954 AMA Arch Otolaryngol pmid:13196799
BELDING HH Acute perforated diverticulitis of the sigmoid colon with generalized peritonitis. 1957 AMA Arch Surg pmid:13410323
REISS E et al. Terramycin in treatment of peritonitis. 1952 AMA Arch Surg pmid:14877394
MATHIEU PL Comparison study: silver nitrate and oxytetracycline in newborn eyes; a comparison of the incidence of conjunctivitis following the instillation of silver nitrate or oxytetracycline into the eyes of newborn infants. 1958 AMA J Dis Child pmid:13532153