oxytetracycline

oxytetracycline is a lipid of Polyketides (PK) class. Oxytetracycline is associated with abnormalities such as Infection, X-linked centronuclear myopathy, Bacterial Infections, Heart failure and Onchocerciasis. The involved functions are known as Anabolism, physiological aspects, Transcription, Genetic, Fermentation and Transcriptional Activation. Oxytetracycline often locates in Chromosomes, Flank (surface region), Entire bony skeleton, Bone Marrow and Body tissue. The associated genes with oxytetracycline are Polypeptides, Homologous Gene, Gene Clusters, Locus and CYCS gene. The related lipids are LH 1 and Lipid Peroxides. The related experimental models are Disease model.

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Introduction

To understand associated biological information of oxytetracycline, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with oxytetracycline?

oxytetracycline is suspected in Infection, Helminthiasis, Nodule, Bacterial Infections, Yeast infection, pathologic fistula and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with oxytetracycline

MeSH term MeSH ID Detail
Hypersensitivity, Delayed D006968 43 associated lipids
Ulna Fractures D014458 2 associated lipids
Esophageal Diseases D004935 3 associated lipids
Ulcer D014456 16 associated lipids
Myocardial Infarction D009203 21 associated lipids
Lymphoma D008223 18 associated lipids
Hematoma D006406 5 associated lipids
Tooth Discoloration D014075 7 associated lipids
Neoplasms, Multiple Primary D009378 8 associated lipids
Vaginitis D014627 6 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with oxytetracycline

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with oxytetracycline?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with oxytetracycline?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with oxytetracycline?

Related references are published most in these journals:

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What genes are associated with oxytetracycline?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with oxytetracycline?

Disease model

Disease model are used in the study 'A molecular ecological approach to the detection and designation of the etiological agents of a model polymicrobial disease.' (Antiabong JF et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with oxytetracycline

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Authors Title Published Journal PubMed Link
Magonigle RA and Newby TJ Response of cattle upon reexposure to Anaplasma marginale after elimination of chronic carrier infections. 1984 Am. J. Vet. Res. pmid:6731981
Nicoletti P et al. Efficacy of various treatment regimens, using liposomal streptomycin in cows with brucellosis. 1989 Am. J. Vet. Res. pmid:2505648
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Magonigle RA et al. Efficacy of a new oxytetracycline formulation against clinical anaplasmosis. 1978 Am. J. Vet. Res. pmid:697150
Wooley RE et al. Inhibitory effects of combinations of oxytetracycline, dimethyl sulfoxide, and EDTA-tromethamine on Escherichia coli. 1981 Am. J. Vet. Res. pmid:6802044
Hatch RC et al. Induced acute aflatoxicosis in goats: treatment with activated charcoal or dual combinations of oxytetracycline, stanozolol, and activated charcoal. 1982 Am. J. Vet. Res. pmid:6803625
Kuttler KL and Simpson JE Relative efficacy of two oxytetracycline formulations and doxycycline in the treatment of acute anaplasmosis in splenectomized calves. 1978 Am. J. Vet. Res. pmid:629473
Clark JD et al. Effects of various treatments on induced chronic aflatoxicosis in rabbits. 1982 Am. J. Vet. Res. pmid:6807140
Wooley RE et al. Antibacterial action of combinations of oxytetracycline, dimethyl sulfoxide, and EDTA-tromethamine on Proteus, Salmonella, and Aeromonas. 1982 Am. J. Vet. Res. pmid:6807142
George LW et al. Effectiveness of two benzathine cloxacillin formulations for treatment of naturally occurring infectious bovine keratoconjunctivitis. 1989 Am. J. Vet. Res. pmid:2774340
Kniffen TS et al. Bioavailability, pharmacokinetics, and plasma concentration of tetracycline hydrochloride fed to swine. 1989 Am. J. Vet. Res. pmid:2712418
Dyer DC Pharmacokinetics of oxytetracycline in the turkey: evaluation of biliary and urinary excretion. 1989 Am. J. Vet. Res. pmid:2712419
Rohde C et al. Effects of phenylbutazone on bone activity and formation in horses. 2000 Am. J. Vet. Res. pmid:10803649
Marín CM et al. Efficacy of long-acting oxytetracycline alone or in combination with streptomycin for treatment of Brucella ovis infection of rams. 1989 Am. J. Vet. Res. pmid:2712423
Wooley RE et al. Attempted reversal of oxytetracycline resistance of Proteus mirabilis by EDTA-tromethamine lavage in experimentally induced canine and feline cystitis. 1975 Am. J. Vet. Res. pmid:811139
Bretzlaff KN et al. Distribution of oxytetracycline in the healthy and diseased postpartum genital tract of cows. 1983 Am. J. Vet. Res. pmid:6869979
Bretzlaff KN et al. Distribution of oxytetracycline in genital tract tissues of postpartum cows given the drug by intravenous and intrauterine routes. 1983 Am. J. Vet. Res. pmid:6869980
Kuttler KL Influence of a second Anaplasma exposure on the success of treatment to eliminate Anaplasma carrier infections in cattle. 1983 Am. J. Vet. Res. pmid:6869997
VanEnkevort BA et al. Alterations in bone remodeling in the femur after medullary reaming and cemented hip arthroplasty in dogs. 1999 Am. J. Vet. Res. pmid:10451197
George LW et al. Comparison of two oxytetracycline formulations in the treatment of laboratory-induced pasteurellosis of pigs. 1983 Am. J. Vet. Res. pmid:6870001
Bowen JM and McMullan WC Influence of induced hypermagnesemia and hypocalcemia on neuromuscular blocking property of oxytetracycline in the horse. 1975 Am. J. Vet. Res. pmid:1147343
YODER HW and PACKER RA Bovine blood serum concentrations of terramycin (Oxytetracycline) following intravenous and intramuscular administration. 1954 Am. J. Vet. Res. pmid:13171501
Miller RA and Reimschuessel R Epidemiologic cutoff values for antimicrobial agents against Aeromonas salmonicida isolates determined by frequency distributions of minimal inhibitory concentration and diameter of zone of inhibition data. 2006 Am. J. Vet. Res. pmid:17078743
Simpson CF Morphologic alterations of Anaplasma marginale in calves after treatment with oxytetracycline. 1975 Am. J. Vet. Res. pmid:1190584
BARNES LE Oxytetracycline in bovine mastitis. I. Treatment of mastitis. 1955 Am. J. Vet. Res. pmid:13238740
Kaneene JB et al. Drug residues in milk after intrauterine injection of oxytetracycline, lincomycin-spectinomycin, and povidone-iodine in cows with metritis. 1986 Am. J. Vet. Res. pmid:2942064
MacNeil JD et al. Bioassay techniques and high-performance liquid chromatography for detection of oxytetracycline residues in tissues from calves. 1989 Am. J. Vet. Res. pmid:2919831
Hewson J et al. Impact of isoflupredone acetate treatment on clinical signs and weight gain in weanling heifers with experimentally induced Mannheimia haemolytica bronchopneumonia. 2011 Am. J. Vet. Res. pmid:22126689
Pindak FF et al. Incidence and distribution of spirochetes in the digestive tract of dogs. 1965 Am. J. Vet. Res. pmid:5882556
Sarmiento JI and Moon HW Postweaning diarrhea in swine: effects of oxytetracycline on enterotoxigenic Escherichia coli infection. 1988 Am. J. Vet. Res. pmid:3048158
Arnoczky SP et al. In vitro effects of oxytetracycline on matrix metalloproteinase-1 mRNA expression and on collagen gel contraction by cultured myofibroblasts obtained from the accessory ligament of foals. 2004 Am. J. Vet. Res. pmid:15077693
Palmer JE et al. Effect of treatment with oxytetracycline during the acute stages of experimentally induced equine ehrlichial colitis in ponies. 1992 Am. J. Vet. Res. pmid:1476312
Oukessou M et al. Pharmacokinetics and local tolerance of a long-acting oxytetracycline formulation in camels. 1992 Am. J. Vet. Res. pmid:1416372
Magonigle RA and Newby TJ Elimination of naturally acquired chronic Anaplasma marginale infections with a long-acting oxytetracycline injectable. 1982 Am. J. Vet. Res. pmid:7165161
Gross DR et al. Adverse cardiovascular effects of oxytetracycline preparations and vehicles in intact awake calves. 1981 Am. J. Vet. Res. pmid:7294473
Abbitt B et al. Effect of dihydrostreptomycin or oxytetracycline on reproductive capacity of bulls. 1984 Am. J. Vet. Res. pmid:6084431
Gyles C et al. In vivo transfer of an Escherichia coli enterotoxin plasmid possessing genes for drug resistance. 1978 Am. J. Vet. Res. pmid:358869
byford RL et al. Chemoprophylaxis of vector-borne anaplasmosis with sustained-release boluses. 1981 Am. J. Vet. Res. pmid:7340579
Larson VL and Stowe CM Plasma and tissue concentrations of oxytetracycline in the horse after intravenous administration. 1981 Am. J. Vet. Res. pmid:7340586
BARNES LE Oxytetracycline in bovine mastitis. II. Milk levels following local and parenteral administration. 1956 Am. J. Vet. Res. pmid:13283224
Fielding CL et al. Evaluation of potential predictor variables for PCR assay diagnosis of Anaplasma phagocytophilum infection in equids in Northern California. 2018 Am. J. Vet. Res. pmid:30085857
Edmondson AJ et al. Survival analysis for evaluation of corneal ulcer healing times in calves with naturally acquired infectious bovine keratoconjunctivitis. 1989 Am. J. Vet. Res. pmid:2764337
Anderson KL et al. Potential for oxytetracycline administration by three routes to cause milk residues in lactating cows, as detected by radioimmunoassay (Charm II) and high-performance liquid chromatography test methods. 1995 Am. J. Vet. Res. pmid:7695153
Ames TR and Patterson EB Oxytetracycline concentrations in plasma and lung of healthy and pneumonic calves, using two oxytetracycline preparations. 1985 Am. J. Vet. Res. pmid:3909863
Simpson CF Morphologic alteration of Paranaplasma caudata following treatment of calves with oxytetracycline. 1977 Am. J. Vet. Res. pmid:931133
Wintz LR et al. Age-dependent effects of systemic administration of oxytetracycline on the viscoelastic properties of rat tail tendons as a mechanistic basis for pharmacological treatment of flexural limb deformities in foals. 2012 Am. J. Vet. Res. pmid:23176422
Button C and Mülders MS Effects of oxytetracycline in propylene glycol, oxytetracycline in saline solution, and propylene glycol alone on blood ionized calcium and plasma total calcium in sheep. 1984 Am. J. Vet. Res. pmid:6476580
Paulsen DB et al. Use of an indwelling bronchial catheter model of bovine pneumonic pasteurellosis for evaluation of therapeutic efficacy of various compounds. 1992 Am. J. Vet. Res. pmid:1524292
Tornquist SJ et al. Use of a polymerase chain reaction assay to study response to oxytetracycline treatment in experimental Candidatus Mycoplasma haemolamae infection in alpacas. 2009 Am. J. Vet. Res. pmid:19719425
Milward FW et al. Effectiveness of various therapeutic regimens for bovine brucellosis. 1984 Am. J. Vet. Res. pmid:6208830