oxytetracycline

oxytetracycline is a lipid of Polyketides (PK) class. Oxytetracycline is associated with abnormalities such as Infection, X-linked centronuclear myopathy, Bacterial Infections, Heart failure and Onchocerciasis. The involved functions are known as Anabolism, physiological aspects, Transcription, Genetic, Fermentation and Transcriptional Activation. Oxytetracycline often locates in Chromosomes, Flank (surface region), Entire bony skeleton, Bone Marrow and Body tissue. The associated genes with oxytetracycline are Polypeptides, Homologous Gene, Gene Clusters, Locus and CYCS gene. The related lipids are LH 1 and Lipid Peroxides. The related experimental models are Disease model.

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Introduction

To understand associated biological information of oxytetracycline, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with oxytetracycline?

oxytetracycline is suspected in Infection, Helminthiasis, Nodule, Bacterial Infections, Yeast infection, pathologic fistula and other diseases in descending order of the highest number of associated sentences.

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Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with oxytetracycline

PubChem Associated disorders and diseases

What pathways are associated with oxytetracycline

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with oxytetracycline?

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What functions are associated with oxytetracycline?


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What lipids are associated with oxytetracycline?

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What genes are associated with oxytetracycline?

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What common seen animal models are associated with oxytetracycline?

Disease model

Disease model are used in the study 'A molecular ecological approach to the detection and designation of the etiological agents of a model polymicrobial disease.' (Antiabong JF et al., 2013).

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NCBI Entrez Crosslinks

All references with oxytetracycline

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Authors Title Published Journal PubMed Link
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Dyer DC Pharmacokinetics of oxytetracycline in the turkey: evaluation of biliary and urinary excretion. 1989 Am. J. Vet. Res. pmid:2712419
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Davis RW et al. The effects of an oxytetracycline preparation on the thyroid gland: a preliminary report. 1966 Am. J. Vet. Res. pmid:5913021
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Simpson CF Morphologic alterations of Anaplasma marginale in calves after treatment with oxytetracycline. 1975 Am. J. Vet. Res. pmid:1190584
Brown MP and MacCallum FJ A system of grading ossification in limbs of foals to assist in radiologic interpretation. 1975 Am. J. Vet. Res. pmid:1137212
BARNES LE Oxytetracycline in bovine mastitis. I. Treatment of mastitis. 1955 Am. J. Vet. Res. pmid:13238740
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Palmer JE et al. Effect of treatment with oxytetracycline during the acute stages of experimentally induced equine ehrlichial colitis in ponies. 1992 Am. J. Vet. Res. pmid:1476312
Magonigle RA and Newby TJ Elimination of naturally acquired chronic Anaplasma marginale infections with a long-acting oxytetracycline injectable. 1982 Am. J. Vet. Res. pmid:7165161
Kuttler KL Efficacy of oxytetracycline and a dithiosemicarbazone in the treatment of bovine anaplasmosis. 1971 Am. J. Vet. Res. pmid:5094519
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Gross DR et al. Cardiovascular effects of intravenous administration of propylene glycol and of oxytetracycline in propylene glycol in calves. 1979 Am. J. Vet. Res. pmid:475130
Abbitt B et al. Effect of dihydrostreptomycin or oxytetracycline on reproductive capacity of bulls. 1984 Am. J. Vet. Res. pmid:6084431
McElroy DE et al. Pharmacokinetics of oxytetracycline hydrochloride in rabbits. 1987 Am. J. Vet. Res. pmid:3631718
Hidalgo RJ Propagation of Anaplasma marginale in bovine lymph node cell culture. 1975 Am. J. Vet. Res. pmid:1094867
BARNES LE Oxytetracycline in bovine mastitis. II. Milk levels following local and parenteral administration. 1956 Am. J. Vet. Res. pmid:13283224
Anderson KL et al. Potential for oxytetracycline administration by three routes to cause milk residues in lactating cows, as detected by radioimmunoassay (Charm II) and high-performance liquid chromatography test methods. 1995 Am. J. Vet. Res. pmid:7695153
Moats WA et al. Comparison of a radioimmunoassay (Charm II) test with high-performance liquid chromatography for detection of oxytetracycline residues in milk samples from lactating cattle. 1995 Am. J. Vet. Res. pmid:7653890
Simpson CF Morphologic alteration of Paranaplasma caudata following treatment of calves with oxytetracycline. 1977 Am. J. Vet. Res. pmid:931133
Wintz LR et al. Age-dependent effects of systemic administration of oxytetracycline on the viscoelastic properties of rat tail tendons as a mechanistic basis for pharmacological treatment of flexural limb deformities in foals. 2012 Am. J. Vet. Res. pmid:23176422
Paulsen DB et al. Use of an indwelling bronchial catheter model of bovine pneumonic pasteurellosis for evaluation of therapeutic efficacy of various compounds. 1992 Am. J. Vet. Res. pmid:1524292
Tornquist SJ et al. Use of a polymerase chain reaction assay to study response to oxytetracycline treatment in experimental Candidatus Mycoplasma haemolamae infection in alpacas. 2009 Am. J. Vet. Res. pmid:19719425
Smith JA and George LW Treatment of acute ocular Moraxella bovis infections in calves with a parenterally administered long-acting oxytetracycline formulation. 1985 Am. J. Vet. Res. pmid:4014830
Milward FW et al. Effectiveness of various therapeutic regimens for bovine brucellosis. 1984 Am. J. Vet. Res. pmid:6208830
Fecteau KA and Eiler H Evaluation of injections of collagenase and oxytetracycline via the umbilical artery as treatment for retained placenta in cattle. 1996 Am. J. Vet. Res. pmid:8712518
Myers MJ et al. In vitro modulation of bovine blood neutrophils and mononuclear cells by oxytetracycline. 1995 Am. J. Vet. Res. pmid:8533970
KILLOUGH JH and MAGILL GB A comparative study of fumagillin and oxytetracycline in amebiasis. 1954 Am. J. Trop. Med. Hyg. pmid:13207553
Albach RA et al. A comparison of in vitro drug sensitivities of strains of entamoeba which grow at 37 degrees C and at room temperature. 1966 Am. J. Trop. Med. Hyg. pmid:5959098
GELFAND M and ALVES WD Terramycin in schistosomiasis; a trial in six cases. 1953 Am. J. Trop. Med. Hyg. pmid:13007928
WEINSTEIN PP et al. Treatment of a case of balantidial dysentery with terramycin. 1952 Am. J. Trop. Med. Hyg. pmid:12996748
LEWIS RA et al. Antibiotic dietary supplements in the therapy of childhood protein malnutrition. 1956 Am. J. Trop. Med. Hyg. pmid:13327183
WILLIAMS RW The growth stimulating effect of APF, terramycin hydrochloride, vitamin B12 and an undetermined factor X upon Aedes aegypti (L) Diptera, Culicidae. 1953 Am. J. Trop. Med. Hyg. pmid:13007931
Nfon CK et al. Lack of resistance after re-exposure of cattle cured of Onchocerca ochengi infection with oxytetracycline. 2007 Am. J. Trop. Med. Hyg. pmid:17255232
CAT ND Terramycin in the treatment of trachoma. 1952 Am. J. Trop. Med. Hyg. pmid:14952704
SCHWABE CW et al. HOST-PARASITE RELATIONSHIPS IN ECHINOCOCCOSIS. IX. IN VITRO SURVIVAL OF HYDATID SCOLICES AND THE EFFECTS OF DRUGS UPON SCOLEX RESPIRATION. 1963 Am. J. Trop. Med. Hyg. pmid:14044745
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TOBIE JE et al. Laboratory results on the efficacy of terramycin, aureomycin and bacitracin in the treatment of asymptomatic amebiasis. 1951 Am. J. Trop. Med. Hyg. pmid:14857244
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PREZYNA AP et al. Treatment of scrub typhus in the Pescadores Islands with chloramphenicol, aureomycin and terramycin. 1954 Am. J. Trop. Med. Hyg. pmid:13180818
HOEKENGA MT Terramycin treatment of balantidiasis in Honduras. 1953 Am. J. Trop. Med. Hyg. pmid:13040661
Williams TW et al. Serratia marcescens as a postoperative pathogen. 1971 Am. J. Surg. pmid:4326385
DIAMOND JJ and IMPINK RR Intraperitoneal administration of terramycin in the treatment of generalized peritonitis. 1957 Am. J. Surg. pmid:13403068
Dillon ML and Bowling KA Effect of antibiotics on wound and stool cultures. Comparison of intravenous terramycin with other antibiotics. 1967 Am. J. Surg. pmid:5334435
ALLEN RF A study of the effect of terramycin on the intestinal flora, with special reference to the accompanying side effects. 1953 Am. J. Surg. pmid:13104764
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Bowden JJ et al. Dexamethasone and oxytetracycline reverse the potentiation of neurogenic inflammation in airways of rats with Mycoplasma pulmonis infection. 1994 Am. J. Respir. Crit. Care Med. pmid:7524980
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Lanman RC et al. Hepatic uptake and biliary excretion of tetracycline in the rat. 1973 Am. J. Physiol. pmid:4745227
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Hardy D et al. The cytology of conjunctival smears from aboriginal school children at Yalata, South Australia. 1967 Am. J. Ophthalmol. pmid:6025178
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ATKINSON WS Half glasses for aphakia. 1955 Am. J. Ophthalmol. pmid:13228542
TOWN AE Ophthalmic use of terramycin. 1951 Am. J. Ophthalmol. pmid:14829487
Hanna C et al. The effect of ophthalmic ointments on corneal wound healing. 1973 Am. J. Ophthalmol. pmid:4353441
Fraunfelder FT et al. Entrapment of ophthalmic ointment in the cornea. 1973 Am. J. Ophthalmol. pmid:4355254
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LOCATCHER-KHORAZO D The effect on the ocular bacterial flora of local treatment with chloromycetin (chloramphenicol), terramycin or penicillin-streptomycin ophthalmic ointments in preoperative cataract cases and miscellaneous infections. 1953 Am. J. Ophthalmol. pmid:13030659
GELLER HO and THYGESON P Aureomycine, chloromycetin, and terramycin in experimental herpes-simplex virus infections. 1951 Am. J. Ophthalmol. pmid:14829527
KURZ GH RETINOPATHY OF OBSCURE (TOXIC?) ORIGIN IN HODGKIN'S DISEASE. 1964 Am. J. Ophthalmol. pmid:14123443
DICKINSON RH Ophthalmic use of terramycin and hydrocortisone. 1955 Am. J. Ophthalmol. pmid:14376470
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SMITH OW et al. The effect of oxytetracycline in pregnancy complicated by glomerular nephritis: a case study. 1954 Am. J. Obstet. Gynecol. pmid:13171424
SHAPIRO LH and LENTZ JW GONORRHEA TREATED WITH OXYTETRACYCLINE. PRELIMINARY REPORT ON THE USE OF VARIOUS DOSAGES IN WOMEN. 1963 Am. J. Obstet. Gynecol. pmid:14056192
Silverman M and Okun R Oxytetracycline-nystatin in the prevention of candidal vaginitis. 1971 Am. J. Obstet. Gynecol. pmid:4937726
Shapiro LH and Lentz JW Final report on the effectiveness of oxytetracycline in the treatment of gonorrhea in females. 1966 Am. J. Obstet. Gynecol. pmid:5903676
SHAPIRO LH Preliminary report of utilization of intramuscular oxytetracycline for treatment of gonorrhea in women. 1962 Am. J. Obstet. Gynecol. pmid:13911301
MIDDLETON TF A clinical evaluation of 25 cases treated with terramycin intramuscular. 1955 Am. J. Obstet. Gynecol. pmid:14361557
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Steigbigel NH et al. Susceptibility of common pathogenic bacteria to seven tetracycline antibiotics in vitro. 1968 Am. J. Med. Sci. pmid:4384524
Massell BF et al. Temporary suppression of penicillinase-producing staphylococci in the throat flora by oxytetracycline. 1966 Am. J. Med. Sci. pmid:5918197
SENECA H and BERGENDAHL E The synergistic amebicidal effect of tetracycline, oxytetracycline and carbomycin on cultures of Endameba histolytica. 1954 Am. J. Med. Sci. pmid:13171377
MOUNTAIN DC and KRUMENACHER FP Oral undecylinic acid in the prevention of the so-called monilial complications secondary to the use of aureomycin, chloramphenicol and terramycin. 1953 Am. J. Med. Sci. pmid:13030464
SAYER RJ et al. Terramycin: clinical, pharmacologic, and bacteriologic studies. 1951 Am. J. Med. Sci. pmid:14810703
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