STERIGMATOCYSTIN

STERIGMATOCYSTIN is a lipid of Polyketides (PK) class. Sterigmatocystin is associated with abnormalities such as CLEFT LIP, CONGENITAL HEALED, Exanthema and Lung diseases. The involved functions are known as sterigmatocystin biosynthetic process, Signal, secondary metabolic process, Biosynthetic Pathways and Anabolism. Sterigmatocystin often locates in Genital system, SAGA complex, Chromosomes, germ tube and Extracellular. The associated genes with STERIGMATOCYSTIN are Genome, Genes, vif, Homologous Gene, Genes, Regulator and Gene Clusters. The related lipids are hexanoic acid, Fatty Acids and Fatty Acids, Unsaturated.

Cross Reference

Introduction

To understand associated biological information of STERIGMATOCYSTIN, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with STERIGMATOCYSTIN?

STERIGMATOCYSTIN is suspected in CLEFT LIP, CONGENITAL HEALED, Exanthema, Lung diseases and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with STERIGMATOCYSTIN

MeSH term MeSH ID Detail
Adenocarcinoma D000230 166 associated lipids
Adenoma D000236 40 associated lipids
Body Weight D001835 333 associated lipids
Cattle Diseases D002418 24 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Esophageal Neoplasms D004938 20 associated lipids
Gastritis D005756 27 associated lipids
Hemangiosarcoma D006394 4 associated lipids
Liver Diseases D008107 31 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with STERIGMATOCYSTIN

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with STERIGMATOCYSTIN?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with STERIGMATOCYSTIN?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with STERIGMATOCYSTIN?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with STERIGMATOCYSTIN?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with STERIGMATOCYSTIN?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with STERIGMATOCYSTIN

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Per page 10 20 50 100 | Total 527
Authors Title Published Journal PubMed Link
Bartoszewska M et al. The significance of peroxisomes in secondary metabolite biosynthesis in filamentous fungi. 2011 Biotechnol. Lett. pmid:21660569
Xu L et al. One-pot synthesis of carbon dots-embedded molecularly imprinted polymer for specific recognition of sterigmatocystin in grains. 2016 Biosens Bioelectron pmid:26544869
Hitchman TS et al. Hexanoate synthase, a specialized type I fatty acid synthase in aflatoxin B1 biosynthesis. 2001 Bioorg. Chem. pmid:16256699
Sun XM et al. Effects of sterigmatocystin, deoxynivalenol and aflatoxin G1 on apoptosis of human peripheral blood lymphocytes in vitro. 2002 Biomed. Environ. Sci. pmid:12244755
Lou JL et al. Production and characterization of sterigmatocystin. 1994 Biomed. Environ. Sci. pmid:7702759
Lou JL et al. Production and characterization of a monoclonal antibody against sterigmatocystin. 1996 Biomed. Environ. Sci. pmid:8721623
Marcet-Houben M et al. Phylogenetic analysis of homologous fatty acid synthase and polyketide synthase involved in aflatoxin biosynthesis. 2008 Bioinformation pmid:19052664
Yao DS et al. A novel biosensor for sterigmatocystin constructed by multi-walled carbon nanotubes (MWNT) modified with aflatoxin-detoxifizyme (ADTZ). 2006 Bioelectrochemistry pmid:16122991
Bhatnagar D and Cleveland TE Fate of the methyl group during the conversion of sterigmatocystin into O-methylsterigmatocystin and aflatoxin B1 by cell-free preparations of Aspergillus parasiticus. 1988 Biochimie pmid:3139090
Gopalakrishnan S et al. Solution structure of the covalent sterigmatocystin-DNA adduct. 1992 Biochemistry pmid:1329956
Black SM et al. Increased sterigmatocystin-induced mutation frequency in Saccharomyces cerevisiae expressing cytochrome P450 CYP2B1. 1992 Biochem. Pharmacol. pmid:1739423
Steyn M and Thiel PG Biliary excretion of sterigmatocystin by vervet monkeys. 1976 Biochem. Pharmacol. pmid:817724
Kim SG and Cho MK Expression of glutathione S-transferases Ya, Yb1, Yb2, Yc1 and Yc2 and microsomal epoxide hydrolase genes by thiazole, benzothiazole and benzothiadiazole. 1996 Biochem. Pharmacol. pmid:8951341
Jeenah MS and Dutton MF The conversion of sterigmatocystin to O-methylsterigmatocystin and aflatoxin B1 by a cell-free preparation. 1983 Biochem. Biophys. Res. Commun. pmid:6418171
Zhang X et al. [Experimental lung carcinoma induced by fungi and mycotoxins--a review]. 2003 Beijing Da Xue Xue Bao pmid:12920799
Bryant BR et al. Acute hepatic necrosis and death in a subadult southern white rhinoceros (Ceratotherium simum) associated with exposure to sterigmatocystin in forage contaminated with Aspergillus nidulans. 2016 Aust. Vet. J. pmid:27785798
Frank HK [Marginals to mycotoxin research (author's transl)]. 1975 Arzneimittelforschung pmid:1243052
Jakšić D et al. Cytotoxicity and genotoxicity of versicolorins and 5-methoxysterigmatocystin in A549 cells. 2012 Arch. Toxicol. pmid:22648070
Jiang X et al. Sterigmatocystin-induced checkpoint adaptation depends on Chk1 in immortalized human gastric epithelial cells in vitro. 2017 Arch. Toxicol. pmid:26914363
Wang J et al. Sterigmatocystin induces G1 arrest in primary human esophageal epithelial cells but induces G2 arrest in immortalized cells: key mechanistic differences in these two models. 2015 Arch. Toxicol. pmid:25294323