STERIGMATOCYSTIN

STERIGMATOCYSTIN is a lipid of Polyketides (PK) class. Sterigmatocystin is associated with abnormalities such as CLEFT LIP, CONGENITAL HEALED, Exanthema and Lung diseases. The involved functions are known as sterigmatocystin biosynthetic process, Signal, secondary metabolic process, Biosynthetic Pathways and Anabolism. Sterigmatocystin often locates in Genital system, SAGA complex, Chromosomes, germ tube and Extracellular. The associated genes with STERIGMATOCYSTIN are Genome, Genes, vif, Homologous Gene, Genes, Regulator and Gene Clusters. The related lipids are hexanoic acid, Fatty Acids and Fatty Acids, Unsaturated.

Cross Reference

Introduction

To understand associated biological information of STERIGMATOCYSTIN, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with STERIGMATOCYSTIN?

STERIGMATOCYSTIN is suspected in CLEFT LIP, CONGENITAL HEALED, Exanthema, Lung diseases and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with STERIGMATOCYSTIN

MeSH term MeSH ID Detail
Adenocarcinoma D000230 166 associated lipids
Lung Neoplasms D008175 171 associated lipids
Cattle Diseases D002418 24 associated lipids
Body Weight D001835 333 associated lipids
Esophageal Neoplasms D004938 20 associated lipids
Precancerous Conditions D011230 48 associated lipids
Gastritis D005756 27 associated lipids
Liver Diseases D008107 31 associated lipids
Weight Gain D015430 101 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with STERIGMATOCYSTIN

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with STERIGMATOCYSTIN?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with STERIGMATOCYSTIN?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with STERIGMATOCYSTIN?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with STERIGMATOCYSTIN?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with STERIGMATOCYSTIN?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with STERIGMATOCYSTIN

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Per page 10 20 50 100 | Total 527
Authors Title Published Journal PubMed Link
Ezekiel CN et al. Fungal and mycotoxin assessment of dried edible mushroom in Nigeria. 2013 Int. J. Food Microbiol. pmid:23454813
Veršilovskis A and Bartkevičs V Stability of sterigmatocystin during the bread making process and its occurrence in bread from the Latvian market. 2012 Mycotoxin Res pmid:23606050
Xie TX [Sterigmatocystin induced adenocarcinoma of the lung and atypical hyperplasia of glandular stomach in mice]. 1990 Zhonghua Zhong Liu Za Zhi pmid:2364865
Zhang D et al. Sterigmatocystin-induced DNA damage triggers G2 arrest via an ATM/p53-related pathway in human gastric epithelium GES-1 cells in vitro. 2013 PLoS ONE pmid:23705030
Cabaret O et al. Metabolic detoxification pathways for 5-methoxy-sterigmatocystin in primary tracheal epithelial cells. 2014 Xenobiotica pmid:23756242
Shantappa S et al. Role of the zinc finger transcription factor SltA in morphogenesis and sterigmatocystin biosynthesis in the fungus Aspergillus nidulans. 2013 PLoS ONE pmid:23840895
Mueller A et al. Individual and combined effects of mycotoxins from typical indoor moulds. 2013 Toxicol In Vitro pmid:23851004
Ramakrishna Y and Bhat RV Minicolumn chromatography for the detection of sterigmatocystin in agricultural commodities. 1990 Mycopathologia pmid:2388681
Nützmann HW et al. Distinct amino acids of histone H3 control secondary metabolism in Aspergillus nidulans. 2013 Appl. Environ. Microbiol. pmid:23892751
Tong PZ et al. Effects of sterigmatocystin on esophageal epithelium and experimental reflux esophagitis in rats. 2013 Mol Med Rep pmid:23942904
Xu YM et al. Secoemestrin D, a cytotoxic epitetrathiodioxopiperizine, and emericellenes A-E, five sesterterpenoids from Emericella sp. AST0036, a fungal endophyte of Astragalus lentiginosus1. 2013 J. Nat. Prod. pmid:24251417
Wang X et al. Inhibitors of neutrophil recruitment identified using transgenic zebrafish to screen a natural product library. 2014 Dis Model Mech pmid:24291762
Meerarani S and Shanmugasundaram ER Preparation of 14C-sterigmatocystin and its in vivo and in vitro binding with macromolecules. 1987 Indian J. Exp. Biol. pmid:2444532
Song F et al. Three new sterigmatocystin analogues from marine-derived fungus Aspergillus versicolor MF359. 2014 Appl. Microbiol. Biotechnol. pmid:24458562
Huang S et al. Impairment of cell cycle progression by sterigmatocystin in human pulmonary cells in vitro. 2014 Food Chem. Toxicol. pmid:24480041
Anninou N et al. Mycotoxins' activity at toxic and sub-toxic concentrations: differential cytotoxic and genotoxic effects of single and combined administration of sterigmatocystin, ochratoxin A and citrinin on the hepatocellular cancer cell line Hep3B. 2014 Int J Environ Res Public Health pmid:24514428
Lee MK et al. NsdD is a key repressor of asexual development in Aspergillus nidulans. 2014 Genetics pmid:24532783
Almeida C et al. Chemical and bioactive natural products from Microthyriaceae sp., an endophytic fungus from a tropical grass. 2014 Lett. Appl. Microbiol. pmid:24612068
Zheng R et al. Simultaneous determination of aflatoxin B(1), B(2), G(1), G(2), ochratoxin A, and sterigmatocystin in traditional Chinese medicines by LC-MS-MS. 2014 Anal Bioanal Chem pmid:24658469
Sasaki R et al. Development of an analytical method for the determination of sterigmatocystin in grains using LCMS after immunoaffinity column purification. 2014 Mycotoxin Res pmid:24696064
Shimada T and Guengerich FP Evidence for cytochrome P-450NF, the nifedipine oxidase, being the principal enzyme involved in the bioactivation of aflatoxins in human liver. 1989 Proc. Natl. Acad. Sci. U.S.A. pmid:2492107
Lee LS Metabolic precursor regulation of aflatoxin formation in toxigenic and non-toxigenic strains of Aspergillus flavus. 1989 Mycopathologia pmid:2515437
Gao W et al. Sterigmatocystin-induced oxidative DNA damage in human liver-derived cell line through lysosomal damage. 2015 Toxicol In Vitro pmid:25176419
Li M et al. An ultra-sensitive monoclonal antibody-based competitive enzyme immunoassay for sterigmatocystin in cereal and oil products. 2014 PLoS ONE pmid:25184275
Baertschi SW et al. Comparison of rates of enzymatic oxidation of aflatoxin B1, aflatoxin G1, and sterigmatocystin and activities of the epoxides in forming guanyl-N7 adducts and inducing different genetic responses. 1989 Mar-Apr Chem. Res. Toxicol. pmid:2519710
Wang J et al. Sterigmatocystin induces G1 arrest in primary human esophageal epithelial cells but induces G2 arrest in immortalized cells: key mechanistic differences in these two models. 2015 Arch. Toxicol. pmid:25294323
Fushimi Y et al. Measurement of sterigmatocystin concentrations in urine for monitoring the contamination of cattle feed. 2014 Toxins (Basel) pmid:25375815
Pfeiffer E et al. Catechol formation: a novel pathway in the metabolism of sterigmatocystin and 11-methoxysterigmatocystin. 2014 Chem. Res. Toxicol. pmid:25380456
Hossain MZ and Goto T Determination of sterigmatocystin in grain using gas chromatography-mass spectrometry with an on-column injector. 2015 Mycotoxin Res pmid:25394696
Bok JW et al. Illumina identification of RsrA, a conserved C2H2 transcription factor coordinating the NapA mediated oxidative stress signaling pathway in Aspergillus. 2014 BMC Genomics pmid:25416206
Wu YZ et al. The furofuran-ring selectivity, hydrogen peroxide-production and low Km value are the three elements for highly effective detoxification of aflatoxin oxidase. 2015 Food Chem. Toxicol. pmid:25533793
Adamson RH Induction of hepatocellular carcinoma in nonhuman primates by chemical carcinogens. 1989 Cancer Detect. Prev. pmid:2559797
Olarte RA et al. Enhanced diversity and aflatoxigenicity in interspecific hybrids of Aspergillus flavus and Aspergillus parasiticus. 2015 Mol. Ecol. pmid:25773520
Biancardi A and Dall'Asta C Determination of sterigmatocystin in feed by LC-MS/MS. 2015 Food Addit Contam Part A Chem Anal Control Expo Risk Assess pmid:26471726
Marley E et al. Analysis of sterigmatocystin in cereals, animal feed, seeds, beer and cheese by immunoaffinity column clean-up and HPLC and LC-MS/MS quantification. 2015 Food Addit Contam Part A Chem Anal Control Expo Risk Assess pmid:26515281
Xu L et al. One-pot synthesis of carbon dots-embedded molecularly imprinted polymer for specific recognition of sterigmatocystin in grains. 2016 Biosens Bioelectron pmid:26544869
Shimada T et al. Human liver microsomal cytochrome P-450 enzymes involved in the bioactivation of procarcinogens detected by umu gene response in Salmonella typhimurium TA 1535/pSK1002. 1989 Cancer Res. pmid:2655891
Bennett JW et al. Sterigmatocystin production on complex and defined substrates. 1989 Mycopathologia pmid:2662007
Moore GG et al. Draft Genome Sequences of Two Closely Related Aflatoxigenic Aspergillus Species Obtained from the Ivory Coast. 2015 Genome Biol Evol pmid:26637470
Zouaoui N et al. Cytotoxic effects induced by patulin, sterigmatocystin and beauvericin on CHO-K1 cells. 2016 Food Chem. Toxicol. pmid:26802678
Korkalainen M et al. Synergistic proinflammatory interactions of microbial toxins and structural components characteristic to moisture-damaged buildings. 2017 Indoor Air pmid:26806918
Shahin MM The importance of analyzing structure-activity relationships in mutagenicity studies. 1989 Mutat. Res. pmid:2682227
Jiang X et al. Sterigmatocystin-induced checkpoint adaptation depends on Chk1 in immortalized human gastric epithelial cells in vitro. 2017 Arch. Toxicol. pmid:26914363
Chung DH et al. Immunochemical assay applied to mycotoxin biosynthesis: ELISA comparison of sterigmatocystin production by Aspergillus versicolor and Aspergillus nidulans. 1989 Mycopathologia pmid:2693965
Despot DJ et al. Species diversity and cytotoxic potency of airborne sterigmatocystin-producing Aspergilli from the section Versicolores. 2016 Sci. Total Environ. pmid:27100010
Cleveland TE Conversion of dihydro-O-methylsterigmatocystin to aflatoxin B2 by Aspergillus parasiticus. 1989 May-Jun Arch. Environ. Contam. Toxicol. pmid:2730159
Liu S et al. Determination of Sterigmatocystin in Infant Cereals from Hangzhou, China. 2016 J AOAC Int pmid:27330032
Orti DL et al. Chromatographic and spectroscopic properties of hemiacetals of aflatoxin and sterigmatocystin metabolites. 1989 J. Chromatogr. pmid:2738124
Jeżak K et al. The capability of fungi isolated from moldy dwellings to produce toxins. 2016 Int J Occup Med Environ Health pmid:27518891
Piontek M et al. Occurrence of the Toxin-Producing Aspergillus versicolor Tiraboschi in Residential Buildings. 2016 Int J Environ Res Public Health pmid:27589778