STERIGMATOCYSTIN

STERIGMATOCYSTIN is a lipid of Polyketides (PK) class. Sterigmatocystin is associated with abnormalities such as CLEFT LIP, CONGENITAL HEALED, Exanthema and Lung diseases. The involved functions are known as sterigmatocystin biosynthetic process, Signal, secondary metabolic process, Biosynthetic Pathways and Anabolism. Sterigmatocystin often locates in Genital system, SAGA complex, Chromosomes, germ tube and Extracellular. The associated genes with STERIGMATOCYSTIN are Genome, Genes, vif, Homologous Gene, Genes, Regulator and Gene Clusters. The related lipids are hexanoic acid, Fatty Acids and Fatty Acids, Unsaturated.

Cross Reference

Introduction

To understand associated biological information of STERIGMATOCYSTIN, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with STERIGMATOCYSTIN?

STERIGMATOCYSTIN is suspected in CLEFT LIP, CONGENITAL HEALED, Exanthema, Lung diseases and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with STERIGMATOCYSTIN

MeSH term MeSH ID Detail
Adenocarcinoma D000230 166 associated lipids
Lung Neoplasms D008175 171 associated lipids
Cattle Diseases D002418 24 associated lipids
Body Weight D001835 333 associated lipids
Esophageal Neoplasms D004938 20 associated lipids
Precancerous Conditions D011230 48 associated lipids
Gastritis D005756 27 associated lipids
Liver Diseases D008107 31 associated lipids
Weight Gain D015430 101 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Adenoma D000236 40 associated lipids
Xeroderma Pigmentosum D014983 6 associated lipids
Hemangiosarcoma D006394 4 associated lipids
Per page 10 20 | Total 14

PubChem Associated disorders and diseases

What pathways are associated with STERIGMATOCYSTIN

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with STERIGMATOCYSTIN?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with STERIGMATOCYSTIN?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with STERIGMATOCYSTIN?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with STERIGMATOCYSTIN?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with STERIGMATOCYSTIN?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with STERIGMATOCYSTIN

Download all related citations
Per page 10 20 50 100 | Total 527
Authors Title Published Journal PubMed Link
Laverty G et al. The potential of antimicrobial peptides as biocides. 2011 Int J Mol Sci pmid:22072905
Cottier F and Mühlschlegel FA Communication in fungi. 2012 Int J Microbiol pmid:21961006
Khaldi N and Wolfe KH Evolutionary Origins of the Fumonisin Secondary Metabolite Gene Cluster in Fusarium verticillioides and Aspergillus niger. 2011 Int J Evol Biol pmid:21716743
Piontek M et al. Occurrence of the Toxin-Producing Aspergillus versicolor Tiraboschi in Residential Buildings. 2016 Int J Environ Res Public Health pmid:27589778
Anninou N et al. Mycotoxins' activity at toxic and sub-toxic concentrations: differential cytotoxic and genotoxic effects of single and combined administration of sterigmatocystin, ochratoxin A and citrinin on the hepatocellular cancer cell line Hep3B. 2014 Int J Environ Res Public Health pmid:24514428
Korkalainen M et al. Synergistic proinflammatory interactions of microbial toxins and structural components characteristic to moisture-damaged buildings. 2017 Indoor Air pmid:26806918
Bloom E et al. Molds and mycotoxins in dust from water-damaged homes in New Orleans after hurricane Katrina. 2009 Indoor Air pmid:19191921
Meerarani S and Shanmugasundaram ER Preparation of 14C-sterigmatocystin and its in vivo and in vitro binding with macromolecules. 1987 Indian J. Exp. Biol. pmid:2444532
Banu S and Shanmugasundaram ER Functional state of rat liver and kidney mitochondria during sterigmatocystin toxicosis. 1988 Indian J. Exp. Biol. pmid:3248844
Banu S and Shanmugasundaram ER Changes in kinetic properties of rat liver gamma-glutamyl transferase during sterigmatocystin toxicity. 1985 Indian J. Biochem. Biophys. pmid:2870981
Meerarani S and Shanmugasundaram ER Effect of sterigmatocystin, a carcinogenic mycotoxin, on urea cycle enzymes and related metabolites in rat liver. 1987 Indian J. Biochem. Biophys. pmid:3623596
Varga J et al. Aspergillus sect. Aeni sect. nov., a new section of the genus for A.karnatakaensis sp. nov. and some allied fungi. 2010 IMA Fungus pmid:22679580
Wang DS et al. Distribution and excretion of 3H-sterigmatocystin in rats. 1991 IARC Sci. Publ. pmid:1855893
Castegnaro M et al. Destruction of sterigmatocystin using sodium hypochlorite. 1991 IARC Sci. Publ. pmid:8778043
Randerath K et al. Biochemical (postlabelling) methods for analysis of carcinogen-DNA adducts. 1984 IARC Sci. Publ. pmid:6443609
McConnell IR and Garner RC DNA adducts of aflatoxins, sterigmatocystin and other mycotoxins. 1994 IARC Sci. Publ. pmid:7806340
Sterigmatocystin. 1976 IARC Monogr Eval Carcinog Risk Chem Man pmid:825430
Sivakumar V et al. Lipid peroxidation as a possible secondary mechanism of sterigmatocystin toxicity. 2001 Hum Exp Toxicol pmid:11727790
Pepeljnjak S et al. The ability of fungal isolates from human lung aspergilloma to produce mycotoxins. 2004 Hum Exp Toxicol pmid:15027811
Zheng P et al. Genome sequence of the insect pathogenic fungus Cordyceps militaris, a valued traditional Chinese medicine. 2011 Genome Biol. pmid:22112802
Khaldi N et al. Evidence for horizontal transfer of a secondary metabolite gene cluster between fungi. 2008 Genome Biol. pmid:18218086
Moore GG et al. Draft Genome Sequences of Two Closely Related Aflatoxigenic Aspergillus Species Obtained from the Ivory Coast. 2015 Genome Biol Evol pmid:26637470
Butchko RA et al. Aspergillus nidulans mutants defective in stc gene cluster regulation. 1999 Genetics pmid:10511551
D'Souza CA et al. Characterization of the role of the FluG protein in asexual development of Aspergillus nidulans. 2001 Genetics pmid:11454752
Seo JA et al. Suppressor mutations bypass the requirement of fluG for asexual sporulation and sterigmatocystin production in Aspergillus nidulans. 2003 Genetics pmid:14668366
Zhang YQ et al. Connection of propionyl-CoA metabolism to polyketide biosynthesis in Aspergillus nidulans. 2004 Genetics pmid:15514053
Seo JA et al. FluG-dependent asexual development in Aspergillus nidulans occurs via derepression. 2006 Genetics pmid:16387865
Shimizu K and Keller NP Genetic involvement of a cAMP-dependent protein kinase in a G protein signaling pathway regulating morphological and chemical transitions in Aspergillus nidulans. 2001 Genetics pmid:11156981
Lee MK et al. NsdD is a key repressor of asexual development in Aspergillus nidulans. 2014 Genetics pmid:24532783
Terao K Mesotheliomas induced by sterigmatocystin in Wistar rats. 1978 Gan pmid:210076
Umeda M et al. Mutagenicity and inducibility of DNA single-strand breaks and chromosome aberrations by various mycotoxins. 1977 Gan pmid:563356
Maekawa A et al. Hepatic changes in male ACI/N rats on low dietary levels of sterigmatocystin. 1979 Gan pmid:535686
Terao K and Ito E The effects of naturally occurring bisdihydrofuran ring-containing mycotoxins on cultured chick embryonal hepatocytes. 1981 Gan pmid:7274652
Dezotti NO and Zucchi TM Identification of Aspergillus nidulans genes essential for the accumulation of sterigmatocystin. 2001 Fungal Genet. Biol. pmid:11686675
Fog Nielsen K Mycotoxin production by indoor molds. 2003 Fungal Genet. Biol. pmid:12781669
Atoui A et al. Cross-talk between light and glucose regulation controls toxin production and morphogenesis in Aspergillus nidulans. 2010 Fungal Genet. Biol. pmid:20816830
Gerke J et al. Fungal S-adenosylmethionine synthetase and the control of development and secondary metabolism in Aspergillus nidulans. 2012 Fungal Genet. Biol. pmid:22561085
Laskowski-Peak MC et al. VEA1 is required for cleistothecial formation and virulence in Histoplasma capsulatum. 2012 Fungal Genet. Biol. pmid:22841690
Reyes-Dominguez Y et al. Heterochromatin influences the secondary metabolite profile in the plant pathogen Fusarium graminearum. 2012 Fungal Genet. Biol. pmid:22100541
Chettri P et al. The veA gene of the pine needle pathogen Dothistroma septosporum regulates sporulation and secondary metabolism. 2012 Fungal Genet. Biol. pmid:22227160
Georgianna DR and Payne GA Genetic regulation of aflatoxin biosynthesis: from gene to genome. 2009 Fungal Genet. Biol. pmid:19010433
Soukup AA et al. The Aspergillus nidulans Pbp1 homolog is required for normal sexual development and secondary metabolism. 2017 Fungal Genet. Biol. pmid:28089630
Brown MP et al. Genetic and molecular analysis of aflatoxin biosynthesis. 1999 Fungal Genet. Biol. pmid:10328980
Rank C et al. Distribution of sterigmatocystin in filamentous fungi. 2011 Apr-May Fungal Biol pmid:21530923
Reijula K and Tuomi T Mycotoxins of aspergilli: exposure and health effects. 2003 Front. Biosci. pmid:12700107
Ohtsubo K et al. High incidence of hepatic tumours in rats fed mouldy rice contaminated with Aspergillus versicolor containing sterigmatocystin. 1978 Food Cosmet Toxicol pmid:208934
Terao K et al. A synergistic effect of nitrosodimethylamine on sterigmatocystin carcinogenesis in rats. 1978 Food Cosmet Toxicol pmid:215497
Zwicker GM et al. Long-term administration of sterigmatocystin and Penicillium viridicatum to mice. 1974 Food Cosmet Toxicol pmid:4459245
Díaz Nieto CH et al. Sterigmatocystin: A mycotoxin to be seriously considered. 2018 Food Chem. Toxicol. pmid:29842907
Cui J et al. The G phase arrest induced by sterigmatocystin is dependent on hMLH1- ERK/p38-p53 pathway in human esophageal epithelium cells in vitro. 2018 Food Chem. Toxicol. pmid:29545144