STERIGMATOCYSTIN

STERIGMATOCYSTIN is a lipid of Polyketides (PK) class. Sterigmatocystin is associated with abnormalities such as CLEFT LIP, CONGENITAL HEALED, Exanthema and Lung diseases. The involved functions are known as sterigmatocystin biosynthetic process, Signal, secondary metabolic process, Biosynthetic Pathways and Anabolism. Sterigmatocystin often locates in Genital system, SAGA complex, Chromosomes, germ tube and Extracellular. The associated genes with STERIGMATOCYSTIN are Genome, Genes, vif, Homologous Gene, Genes, Regulator and Gene Clusters. The related lipids are hexanoic acid, Fatty Acids and Fatty Acids, Unsaturated.

Cross Reference

Introduction

To understand associated biological information of STERIGMATOCYSTIN, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with STERIGMATOCYSTIN?

STERIGMATOCYSTIN is suspected in CLEFT LIP, CONGENITAL HEALED, Exanthema, Lung diseases and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with STERIGMATOCYSTIN

MeSH term MeSH ID Detail
Adenocarcinoma D000230 166 associated lipids
Lung Neoplasms D008175 171 associated lipids
Cattle Diseases D002418 24 associated lipids
Body Weight D001835 333 associated lipids
Esophageal Neoplasms D004938 20 associated lipids
Precancerous Conditions D011230 48 associated lipids
Gastritis D005756 27 associated lipids
Liver Diseases D008107 31 associated lipids
Weight Gain D015430 101 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Adenoma D000236 40 associated lipids
Xeroderma Pigmentosum D014983 6 associated lipids
Hemangiosarcoma D006394 4 associated lipids
Per page 10 20 | Total 14

PubChem Associated disorders and diseases

What pathways are associated with STERIGMATOCYSTIN

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with STERIGMATOCYSTIN?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with STERIGMATOCYSTIN?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with STERIGMATOCYSTIN?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with STERIGMATOCYSTIN?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with STERIGMATOCYSTIN?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with STERIGMATOCYSTIN

Download all related citations
Per page 10 20 50 100 | Total 527
Authors Title Published Journal PubMed Link
Sivakumar V et al. Lipid peroxidation as a possible secondary mechanism of sterigmatocystin toxicity. 2001 Hum Exp Toxicol pmid:11727790
D'Souza CA et al. Characterization of the role of the FluG protein in asexual development of Aspergillus nidulans. 2001 Genetics pmid:11454752
Dezotti NO and Zucchi TM Identification of Aspergillus nidulans genes essential for the accumulation of sterigmatocystin. 2001 Fungal Genet. Biol. pmid:11686675
Klich M et al. A new sterigmatocystin-producing Emericella variant from agricultural desert soils. 2001 Syst. Appl. Microbiol. pmid:11403392
Shimizu K and Keller NP Genetic involvement of a cAMP-dependent protein kinase in a G protein signaling pathway regulating morphological and chemical transitions in Aspergillus nidulans. 2001 Genetics pmid:11156981
Cao W et al. [Mutation of p53 and Ki-ras gene in human fetal lung fibroblast cells in vitro by sterigmatocystin]. 2000 Wei Sheng Yan Jiu pmid:12725069
Keller NP et al. Requirement of monooxygenase-mediated steps for sterigmatocystin biosynthesis by Aspergillus nidulans. 2000 Appl. Environ. Microbiol. pmid:10618248
Xie TX et al. Absence of p53-mediated G1 arrest with induction of MDM2 in sterigmatocystin-treated cells. 2000 Int. J. Oncol. pmid:10995885
Klich MA et al. Molecular and physiological aspects of aflatoxin and sterigmatocystin biosynthesis by Aspergillus tamarii and A. ochraceoroseus. 2000 Appl. Microbiol. Biotechnol. pmid:10855723
Cary JW et al. Generation of aflR disruption mutants of Aspergillus parasiticus. 2000 Appl. Microbiol. Biotechnol. pmid:10919326
Motomura M et al. Cloning and characterization of the O-methyltransferase I gene (dmtA) from Aspergillus parasiticus associated with the conversions of demethylsterigmatocystin to sterigmatocystin and dihydrodemethylsterigmatocystin to dihydrosterigmatocystin in aflatoxin biosynthesis. 1999 Appl. Environ. Microbiol. pmid:10543813
Butchko RA et al. Aspergillus nidulans mutants defective in stc gene cluster regulation. 1999 Genetics pmid:10511551
Brown MP et al. Genetic and molecular analysis of aflatoxin biosynthesis. 1999 Fungal Genet. Biol. pmid:10328980
Gengan RM et al. Synthesis of sterigmatocystin derivatives and their biotransformation to aflatoxins by a blocked mutant of Aspergillus parasiticus. 1998-1999 Mycopathologia pmid:10481291
Feng GH and Leonard TJ Culture conditions control expression of the genes for aflatoxin and sterigmatocystin biosynthesis in Aspergillus parasiticus and A. nidulans. 1998 Appl. Environ. Microbiol. pmid:9603849
Guzmán-de-Peña D et al. Correlation between the regulation of sterigmatocystin biosynthesis and asexual and sexual sporulation in Emericella nidulans. 1998 Antonie Van Leeuwenhoek pmid:9717578
Adams TH and Yu JH Coordinate control of secondary metabolite production and asexual sporulation in Aspergillus nidulans. 1998 Curr. Opin. Microbiol. pmid:10066549
Sun X et al. [Mutation of p53 gene in human fetal gastric mucosal cells by sterigmatocystin in vitro]. 1998 Wei Sheng Yan Jiu pmid:10682599
Meyers DM et al. Characterization of aflJ, a gene required for conversion of pathway intermediates to aflatoxin. 1998 Appl. Environ. Microbiol. pmid:9758789
Fernandes M et al. Sequence-specific binding by Aspergillus nidulans AflR, a C6 zinc cluster protein regulating mycotoxin biosynthesis. 1998 Mol. Microbiol. pmid:9680223
Sweeney MJ and Dobson AD Mycotoxin production by Aspergillus, Fusarium and Penicillium species. 1998 Int. J. Food Microbiol. pmid:9801191
Woloshuk CP and Prieto R Genetic organization and function of the aflatoxin B1 biosynthetic genes. 1998 FEMS Microbiol. Lett. pmid:9532734
Wieser J et al. Dominant mutations affecting both sporulation and sterigmatocystin biosynthesis in Aspergillus nidulans. 1997 Curr. Genet. pmid:9339347
Prieto R and Woloshuk CP ord1, an oxidoreductase gene responsible for conversion of O-methylsterigmatocystin to aflatoxin in Aspergillus flavus. 1997 Appl. Environ. Microbiol. pmid:9143099
Kelkar HS et al. Aspergillus nidulans stcL encodes a putative cytochrome P-450 monooxygenase required for bisfuran desaturation during aflatoxin/sterigmatocystin biosynthesis. 1997 J. Biol. Chem. pmid:8999832
Hicks JK et al. Aspergillus sporulation and mycotoxin production both require inactivation of the FadA G alpha protein-dependent signaling pathway. 1997 EMBO J. pmid:9305634
Zhang X et al. [Effects of sterigmatocystin on ras p21 expression and ultrastructure of human lung fibroblasts in vitro]. 1997 Wei Sheng Yan Jiu pmid:10325614
Brown DW et al. Twenty-five coregulated transcripts define a sterigmatocystin gene cluster in Aspergillus nidulans. 1996 Proc. Natl. Acad. Sci. U.S.A. pmid:8643646
Yu JH et al. Conservation of structure and function of the aflatoxin regulatory gene aflR from Aspergillus nidulans and A. flavus. 1996 Curr. Genet. pmid:8662194
Scudamore KA et al. Analytical methods for the determination of sterigmatocystin in cheese, bread and corn products using HPLC with atmospheric pressure ionization mass spectrometric detection. 1996 Food Addit Contam pmid:8718750
Lou JL et al. Production and characterization of a monoclonal antibody against sterigmatocystin. 1996 Biomed. Environ. Sci. pmid:8721623
Kelkar HS et al. Aspergillus nidulans stcP encodes an O-methyltransferase that is required for sterigmatocystin biosynthesis. 1996 Appl. Environ. Microbiol. pmid:8900026
Prieto R et al. Identification of aflatoxin biosynthesis genes by genetic complementation in an Aspergillus flavus mutant lacking the aflatoxin gene cluster. 1996 Appl. Environ. Microbiol. pmid:8967772
Kim SG and Cho MK Expression of glutathione S-transferases Ya, Yb1, Yb2, Yc1 and Yc2 and microsomal epoxide hydrolase genes by thiazole, benzothiazole and benzothiadiazole. 1996 Biochem. Pharmacol. pmid:8951341
Abd Alla EA et al. Sterigmatocystin: incidence, fate and production by Aspergillus versicolor in Ras cheese. 1996 Nahrung pmid:9008831
Lou J et al. [Preparation and identification of monoclonal antibody against sterigmatocystin]. 1995 Zhonghua Yu Fang Yi Xue Za Zhi pmid:7796690
Klich MA et al. Hybridization of genes involved in aflatoxin biosynthesis to DNA of aflatoxigenic and non-aflatoxigenic aspergilli. 1995 Appl. Microbiol. Biotechnol. pmid:8597546
Lou J et al. [Production and characterization of sterigmatocystin]. 1995 Wei Sheng Wu Xue Bao pmid:8701584
Tian H et al. [Determination of sterigmatocystin in cancerous tissues, blood and urine in patients with liver and stomach cancer]. 1995 Zhonghua Yu Fang Yi Xue Za Zhi pmid:8556937
Keller NP et al. stcS, a putative P-450 monooxygenase, is required for the conversion of versicolorin A to sterigmatocystin in Aspergillus nidulans. 1995 Appl. Environ. Microbiol. pmid:7486998
Walsh AA et al. 2,3,7,8-Tetrachlorodibenzo-p-dioxin sensitization of cultured human epidermal cells to carcinogenic heterocyclic amine toxicity. 1995 Carcinogenesis pmid:7554073
Yu JH and Leonard TJ Sterigmatocystin biosynthesis in Aspergillus nidulans requires a novel type I polyketide synthase. 1995 J. Bacteriol. pmid:7642507
Keller NP and Adams TH Analysis of a mycotoxin gene cluster in Aspergillus nidulans. 1995 SAAS Bull. Biochem. Biotechnol. pmid:7546572
El-Kady IA et al. Natural occurrence of mycotoxins in different spices in Egypt. 1995 Folia Microbiol. (Praha) pmid:8919936
Volkov NV [The diagnosis of mycotoxin hepatitis in swine]. 1994 Sep-Oct Mikrobiol. Z. pmid:7834101
Venitt S and Biggs PJ Radon, mycotoxins, p53, and uranium mining. 1994 Lancet pmid:7907754
Barnes SE et al. Synthesis of sterigmatocystin on a chemically defined medium by species of Aspergillus and Chaetomium. 1994 Mycopathologia pmid:8047108
McConnell IR and Garner RC DNA adducts of aflatoxins, sterigmatocystin and other mycotoxins. 1994 IARC Sci. Publ. pmid:7806340
Hodges RL et al. Genetic modification of an echinocandin B-producing strain of Aspergillus nidulans to produce mutants blocked in sterigmatocystin biosynthesis. 1994 J. Ind. Microbiol. pmid:7765669
Ji X et al. Effects of sterigmatocystin and T-2 toxin on the induction of unscheduled DNA synthesis in primary cultures of human gastric epithelial cells. 1994 Nat. Toxins pmid:8087430