STERIGMATOCYSTIN

STERIGMATOCYSTIN is a lipid of Polyketides (PK) class. Sterigmatocystin is associated with abnormalities such as CLEFT LIP, CONGENITAL HEALED, Exanthema and Lung diseases. The involved functions are known as sterigmatocystin biosynthetic process, Signal, secondary metabolic process, Biosynthetic Pathways and Anabolism. Sterigmatocystin often locates in Genital system, SAGA complex, Chromosomes, germ tube and Extracellular. The associated genes with STERIGMATOCYSTIN are Genome, Genes, vif, Homologous Gene, Genes, Regulator and Gene Clusters. The related lipids are hexanoic acid, Fatty Acids and Fatty Acids, Unsaturated.

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Introduction

To understand associated biological information of STERIGMATOCYSTIN, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with STERIGMATOCYSTIN?

STERIGMATOCYSTIN is suspected in CLEFT LIP, CONGENITAL HEALED, Exanthema, Lung diseases and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with STERIGMATOCYSTIN

MeSH term MeSH ID Detail
Liver Neoplasms, Experimental D008114 46 associated lipids
Adenoma D000236 40 associated lipids
Xeroderma Pigmentosum D014983 6 associated lipids
Hemangiosarcoma D006394 4 associated lipids
Per page 10 20 | Total 14

PubChem Associated disorders and diseases

What pathways are associated with STERIGMATOCYSTIN

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with STERIGMATOCYSTIN?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with STERIGMATOCYSTIN?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with STERIGMATOCYSTIN?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with STERIGMATOCYSTIN?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with STERIGMATOCYSTIN?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with STERIGMATOCYSTIN

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Authors Title Published Journal PubMed Link
Lepom P Determination of sterigmatocystin in feed by high-performance liquid chromatography with column switching. 1986 J. Chromatogr. pmid:3700539
Duraković S [Mycotoxins as carcinogenic agents]. 1985 Nov-Dec Lijec Vjesn pmid:3908865
Pachter R and Steyn PS Quantum-chemical studies of aflatoxin B1, sterigmatocystin and versicolorin A, and a comparison with their mutagenic activity. 1985 May-Jun Mutat. Res. pmid:3923331
Dutton MF et al. Biosynthetic relationship among aflatoxins B1, B2, M1, and M2. 1985 Appl. Environ. Microbiol. pmid:3925881
Wehner FC et al. Mutagenicity of 5,6-dimethoxysterigmatocystin, a metabolite from Aspergillus multicolor, in the Salmonella/microsome system. 1979 Appl. Environ. Microbiol. pmid:396882
Vesonder RF and Horn BW Sterigmatocystin in dairy cattle feed contaminated with Aspergillus versicolor. 1985 Appl. Environ. Microbiol. pmid:3977312
Francis OJ et al. Thin layer chromatographic determination of sterigmatocystin in cheese. 1985 Jul-Aug J Assoc Off Anal Chem pmid:4030632
Reddy MV et al. Formation and persistence of sterigmatocystin--DNA adducts in rat liver determined via 32P-postlabeling analysis. 1985 Mutat. Res. pmid:4047087
Schroeder HW and Hein H Natural occurrence of sterigmatocystin in in-shell pecans. 1977 Can. J. Microbiol. pmid:406023
Rabie CJ et al. New species of Aspergillus producing sterigmatocystin. 1977 Appl. Environ. Microbiol. pmid:406838
Chen PN et al. Reduction of sterigmatocystin and versicolorin A hemiacetals with sodium borohydride. 1977 J. Org. Chem. pmid:410911
Udagawa S et al. The production of chaetoglobosins, sterigmatocystin, O-methylsterigmatocystin, and chaetocin by Chaetomium spp. and related fungi. 1979 Can. J. Microbiol. pmid:436014
Mabuchi M Sequential hepatic changes during sterigmatocystin-induced carcinogenesis in the rat. 1979 Jpn. J. Exp. Med. pmid:44322
Zwicker GM et al. Long-term administration of sterigmatocystin and Penicillium viridicatum to mice. 1974 Food Cosmet Toxicol pmid:4459245
Zamir LO and Ginsburg R Aflatoxin biosynthesis: detection of transient, acetate-dependent intermediates in Aspergillus by kinetic pulse-labeling. 1979 J. Bacteriol. pmid:457592
Thurm V et al. [Hygienic significance of sterigmatocystin in vegetable foods. 1. Analytical detection of sterigmatocystin]. 1979 Nahrung pmid:471029
Paul P and Thurm V [Hygienic significance of sterigmatocystin in vegetable foods. 2. Production of sterigmatocystin by Aspergillus versicolor]. 1979 Nahrung pmid:471030
Thurm V et al. [Hygienic significance of sterigmatocystin in vegetable foods. 3. Occurrence of sterigmatocystin]. 1979 Nahrung pmid:471031
Mojtahedi H et al. Toxic aspergilli from pistachio nuts. 1979 Mycopathologia pmid:481560
Maekawa A et al. Hepatic changes in male ACI/N rats on low dietary levels of sterigmatocystin. 1979 Gan pmid:535686
Gorst-Allman CP et al. Oxidation of the bisdihydrofuran moieties of aflatoxin B1 and sterigmatocystin; conformation of tetrahydrofurobenzofurans. 1977 J. Chem. Soc. Perkin Trans. I pmid:559687
Umeda M et al. Mutagenicity and inducibility of DNA single-strand breaks and chromosome aberrations by various mycotoxins. 1977 Gan pmid:563356
Weiss R [Mycotoxins and their significance for the human and animal health]. 1978 Tierarztl Prax pmid:580511
Singh R and Hsieh DP Enzymatic conversion of sterigmatocystin into aflatoxin B1 by cell-free extracts of Aspergillus parasiticus. 1976 Appl. Environ. Microbiol. pmid:5954
Le Bars J [Bioproduction of sterigmatocystine by Aspergillus versicolor (Vuill.) tiraboschi in dry fodder]. 1977 Ann Nutr Aliment pmid:613923
Patterson DS Metabolic activation and detoxification of mycotoxins. 1977 Ann Nutr Aliment pmid:613940
Tutel'ian VA and Kravchenko LV [New data on the metabolism and mechanism of action of mycotoxins]. 1981 Vestn. Akad. Med. Nauk SSSR pmid:6162293
Perry MJ et al. The effect of the synergy between sterigmatocystin and a fungal metabolite on Bacillus subtilis. 1982 J. Appl. Bacteriol. pmid:6175614
Ito N et al. Comparison of the promoting effects of various agents in induction of preneoplastic lesions in rat liver. 1983 Environ. Health Perspect. pmid:6191977
Douros JD Lower plants as a source of anticancer drugs. 1976 Cancer Treat Rep pmid:62614
Richard JL et al. Complement activity, serum protein, and hepatic changes in guinea pigs given sterigmatocystin or aflatoxin, alone or in combination. 1978 Am. J. Vet. Res. pmid:629440
Bartos J and Matyás Z [Study of the presence of sterigmatocystin in Czechoslovak grain]. 1983 Vet Med (Praha) pmid:6405538
Chinnici JP et al. Effects of mycotoxin pretreatment on aflatoxin B1 post-treatment toxicity in Drosophila melanogaster (Diptera). 1983 J. Invertebr. Pathol. pmid:6408193
Jeenah MS and Dutton MF The conversion of sterigmatocystin to O-methylsterigmatocystin and aflatoxin B1 by a cell-free preparation. 1983 Biochem. Biophys. Res. Commun. pmid:6418171
Randerath K et al. Biochemical (postlabelling) methods for analysis of carcinogen-DNA adducts. 1984 IARC Sci. Publ. pmid:6443609
Curry PT et al. Induction of sister-chromatid exchanges in vivo in mice by the mycotoxins sterigmatocystin and griseofulvin. 1984 Aug-Sep Mutat. Res. pmid:6472322
Kawai K et al. Inhibitory effect of sterigmatocystin and 5,6-dimethoxysterigmatocystin on ATP synthesis in mitochondria. 1984 Appl. Environ. Microbiol. pmid:6508300
Hsieh DP et al. Anthraquinones in the biosynthesis of sterigmatocystin by Aspergillus versicolor. 1978 Appl. Environ. Microbiol. pmid:655714
Bennett JW and Christensen SB New perspectives on aflatoxin biosynthesis. 1983 Adv. Appl. Microbiol. pmid:6650265
Ueda N et al. Acute cytogenetic effect of sterigmatocystin on rat bone-marrow cells in vivo. 1984 Mutat. Res. pmid:6717486
Hitokoto H et al. Inhibitory effects of spices on growth and toxin production of toxigenic fungi. 1980 Appl. Environ. Microbiol. pmid:6769391
Essigmann JM et al. Use of the isolated perfused rat liver to study carcinogen-DNA adduct formation from aflatoxin B1 and sterigmatocystin. 1980 Cancer Res. pmid:6781740
Zamir LO and Hufford KD Precursor recognition by kinetic pulse-labeling in a toxigenic aflatoxin B1-producing strain of Aspergillus. 1981 Appl. Environ. Microbiol. pmid:6789767
Applebaum RS and Marth EH Biogenesis of the C20 polyketide, aflatoxin. A review. 1981 Mycopathologia pmid:6798444
Perry MJ et al. The isolation of a fungal metabolite which exhibits antimicrobial synergy with sterigmatocystin. 1982 J. Appl. Bacteriol. pmid:6802793
Gunst K et al. Effects of aflatoxin B, aflatoxin B, aflatoxin G and sterigmatocystin on viability, rates of development, and body length in two strains of Drosophila melanogaster (Diptera). 1982 J. Invertebr. Pathol. pmid:6806396
Bartos J and Matyás Z [Study of cheeses for the presence of sterigmatocystin]. 1982 Vet Med (Praha) pmid:6818752
Czerwiecki L [Detection and determination of the content of selected mycotoxins in grain]. 1982 Rocz Panstw Zakl Hig pmid:6820849
Enomoto M et al. High incidence of angiosarcomas in brown-fat tissue and livers of mice fed sterigmatocystin. 1982 Food Chem. Toxicol. pmid:6890509
Hendricks JD et al. Hepatocarcinogenicity of sterigmatocystin and versicolorin A to rainbow trout (Salmo gairdneri) embryos. 1980 J. Natl. Cancer Inst. pmid:6929388
Hitokoto H et al. Fungal contamination and mycotoxin detection of powdered herbal drugs. 1978 Appl. Environ. Microbiol. pmid:697361
Stark AA Mutagenicity and carcinogenicity of mycotoxins: DNA binding as a possible mode of action. 1980 Annu. Rev. Microbiol. pmid:7002024
Fincham JE et al. Squamous cell carcinoma in an African green monkey. 1982 Vet. Pathol. pmid:7090145
Hitokoto H et al. Chemically defined medium for high yields of sterigmatocystin. 1982 Mycopathologia pmid:7099245
Schmidt R et al. High-performance liquid chromatography of the mycotoxin sterigmatocystin and its application to the analysis of mouldy rice for sterigmatocystin. 1981 J. Chromatogr. pmid:7228939
Terao K and Ito E The effects of naturally occurring bisdihydrofuran ring-containing mycotoxins on cultured chick embryonal hepatocytes. 1981 Gan pmid:7274652
Szebiotko K et al. Mycotoxins in cereal grain. Part I. Ochratoxin, citrinin, sterigmatocystin, penicillic acid and toxigenic fungi in cereal grain. 1981 Nahrung pmid:7278949
Sekita S et al. Mycotoxin production by Chaetomium spp. and related fungi. 1981 Can. J. Microbiol. pmid:7296410
Ayer WA et al. Identification of sterigmatocystin as a metabolite of Monocillium nordinii. 1981 Can. J. Microbiol. pmid:7296415
Noda K et al. Cytotoxic and mutagenic effects of sterigmatocystin on cultured Chinese hamster cells. 1981 Carcinogenesis pmid:7296761
van Egmond HP et al. Thin layer chromatographic method for analysis and chemical confirmation of sterigmatocystin in cheese. 1980 J Assoc Off Anal Chem pmid:7380781
Northolt MD et al. Fungal growth and the presence of sterigmatocystin in hard cheese. 1980 J Assoc Off Anal Chem pmid:7380782
Hendricks JD et al. Rainbow trout (Salmo gairdneri) embryos: a sensitive animal model for experimental carcinogenesis. 1980 Fed. Proc. pmid:7439406
Gertz C and Böschemeyer L [A screening method for the determination of various mycotoxins in food (author's transl)]. 1980 Z Lebensm Unters Forsch pmid:7445756
Keller NP et al. stcS, a putative P-450 monooxygenase, is required for the conversion of versicolorin A to sterigmatocystin in Aspergillus nidulans. 1995 Appl. Environ. Microbiol. pmid:7486998
Rodriguez-Arnaiz R and Aranda JH Metabolic activation of four drugs in the eye mosaic assay measuring principally mitotic recombination in Drosophila melanogaster: differences in strain susceptibility and route of exposure. 1994 Mutat. Res. pmid:7510026
Zohri AA and Ismail MA Based on biochemical and physiological behavior, where is Aspergillus egyptiacus better placed? 1994 Folia Microbiol. (Praha) pmid:7537240
Keller NP and Adams TH Analysis of a mycotoxin gene cluster in Aspergillus nidulans. 1995 SAAS Bull. Biochem. Biotechnol. pmid:7546572
Walsh AA et al. 2,3,7,8-Tetrachlorodibenzo-p-dioxin sensitization of cultured human epidermal cells to carcinogenic heterocyclic amine toxicity. 1995 Carcinogenesis pmid:7554073
Yu JH and Leonard TJ Sterigmatocystin biosynthesis in Aspergillus nidulans requires a novel type I polyketide synthase. 1995 J. Bacteriol. pmid:7642507
Miller JA and Miller EC Carcinogens occurring naturally in foods. 1976 Fed. Proc. pmid:770205
Lou JL et al. Production and characterization of sterigmatocystin. 1994 Biomed. Environ. Sci. pmid:7702759
Hodges RL et al. Genetic modification of an echinocandin B-producing strain of Aspergillus nidulans to produce mutants blocked in sterigmatocystin biosynthesis. 1994 J. Ind. Microbiol. pmid:7765669
Lou J et al. [Preparation and identification of monoclonal antibody against sterigmatocystin]. 1995 Zhonghua Yu Fang Yi Xue Za Zhi pmid:7796690
McConnell IR and Garner RC DNA adducts of aflatoxins, sterigmatocystin and other mycotoxins. 1994 IARC Sci. Publ. pmid:7806340
Volkov NV [The diagnosis of mycotoxin hepatitis in swine]. 1994 Sep-Oct Mikrobiol. Z. pmid:7834101
Venitt S and Biggs PJ Radon, mycotoxins, p53, and uranium mining. 1994 Lancet pmid:7907754
Jesenská Z and Bernát D Effect of mycotoxins on in vitro movement of tracheal cilia from one-day-old chicks. 1994 Folia Microbiol. (Praha) pmid:7959432
García ME et al. A red pigment synthesized by an Aspergillus parasiticus mutant as a possible new intermediate in the aflatoxin biosynthetic pathway. 1994 J. Appl. Bacteriol. pmid:8002480
Keller NP et al. Aspergillus nidulans verA is required for production of the mycotoxin sterigmatocystin. 1994 Appl. Environ. Microbiol. pmid:8017929
Barnes SE et al. Synthesis of sterigmatocystin on a chemically defined medium by species of Aspergillus and Chaetomium. 1994 Mycopathologia pmid:8047108
Ji X et al. Effects of sterigmatocystin and T-2 toxin on the induction of unscheduled DNA synthesis in primary cultures of human gastric epithelial cells. 1994 Nat. Toxins pmid:8087430
Schroeder HW and Kelton WH Production of sterigmatocystin by some species of the genus Aspergillus and its toxicity to chicken embryos. 1975 Appl Microbiol pmid:811164
Ueno Y and Kubota K DNA-attacking ability of carcinogenic mycotoxins in recombination-deficient mutant cells of Bacillus subtilis. 1976 Cancer Res. pmid:816461
Steyn M and Thiel PG Biliary excretion of sterigmatocystin by vervet monkeys. 1976 Biochem. Pharmacol. pmid:817724
Sommer NF et al. Aflatoxin and sterigmatocystin contamination of pistachio nuts in orchards. 1976 Appl. Environ. Microbiol. pmid:823868
Sterigmatocystin. 1976 IARC Monogr Eval Carcinog Risk Chem Man pmid:825430
Iwata K [Current status of fungl toxin studies (author's transl)]. 1976 Tanpakushitsu Kakusan Koso pmid:829167
Septien I et al. Solubility and stability of sterigmatocystin in different organic solvents. 1993 Toxicon pmid:8303729
Cox RH and Cole RJ Carbon-13 nuclear magnetic resonance studies of fungal metabolites, aflatoxins, and sterigmatocystins. 1977 J. Org. Chem. pmid:830848
Athnasios AK and Kuhn GO Improved thin layer chromatographic method for the isolation and estimation of sterigmatocystin in grains. 1977 J Assoc Off Anal Chem pmid:833082
Singh R and Hsieh DP Aflatoxin biosynthetic pathway: elucidation by using blocked mutants of Aspergillus parasiticus. 1977 Arch. Biochem. Biophys. pmid:836036
Xie TX [Effects of extract solution of Aspergillus versicolor on human fetal gastric cells in vitro]. 1993 Zhonghua Yi Xue Za Zhi pmid:8391901
Lisker N et al. Mycotoxigenic potential of Aspergillus flavus strains isolated from groundnuts growing in Israel. 1993 Mycopathologia pmid:8413500
Tian H et al. [Determination of sterigmatocystin in cancerous tissues, blood and urine in patients with liver and stomach cancer]. 1995 Zhonghua Yu Fang Yi Xue Za Zhi pmid:8556937
Klich MA et al. Hybridization of genes involved in aflatoxin biosynthesis to DNA of aflatoxigenic and non-aflatoxigenic aspergilli. 1995 Appl. Microbiol. Biotechnol. pmid:8597546
Brown DW et al. Twenty-five coregulated transcripts define a sterigmatocystin gene cluster in Aspergillus nidulans. 1996 Proc. Natl. Acad. Sci. U.S.A. pmid:8643646
Chavant L et al. [Lipid metabolism in Aspergillus versicolor (Vuill.) Tiragoschi. Relation to biogenesis of sterigmatocystin]. 1977 Mycopathologia pmid:865598
Yu JH et al. Conservation of structure and function of the aflatoxin regulatory gene aflR from Aspergillus nidulans and A. flavus. 1996 Curr. Genet. pmid:8662194
Lou J et al. [Production and characterization of sterigmatocystin]. 1995 Wei Sheng Wu Xue Bao pmid:8701584