STERIGMATOCYSTIN

STERIGMATOCYSTIN is a lipid of Polyketides (PK) class. Sterigmatocystin is associated with abnormalities such as CLEFT LIP, CONGENITAL HEALED, Exanthema and Lung diseases. The involved functions are known as sterigmatocystin biosynthetic process, Signal, secondary metabolic process, Biosynthetic Pathways and Anabolism. Sterigmatocystin often locates in Genital system, SAGA complex, Chromosomes, germ tube and Extracellular. The associated genes with STERIGMATOCYSTIN are Genome, Genes, vif, Homologous Gene, Genes, Regulator and Gene Clusters. The related lipids are hexanoic acid, Fatty Acids and Fatty Acids, Unsaturated.

Cross Reference

Introduction

To understand associated biological information of STERIGMATOCYSTIN, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with STERIGMATOCYSTIN?

STERIGMATOCYSTIN is suspected in CLEFT LIP, CONGENITAL HEALED, Exanthema, Lung diseases and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with STERIGMATOCYSTIN

MeSH term MeSH ID Detail
Adenocarcinoma D000230 166 associated lipids
Adenoma D000236 40 associated lipids
Body Weight D001835 333 associated lipids
Cattle Diseases D002418 24 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Esophageal Neoplasms D004938 20 associated lipids
Gastritis D005756 27 associated lipids
Hemangiosarcoma D006394 4 associated lipids
Liver Diseases D008107 31 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Per page 10 20 | Total 14

PubChem Associated disorders and diseases

What pathways are associated with STERIGMATOCYSTIN

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with STERIGMATOCYSTIN?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with STERIGMATOCYSTIN?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with STERIGMATOCYSTIN?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with STERIGMATOCYSTIN?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with STERIGMATOCYSTIN?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with STERIGMATOCYSTIN

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Authors Title Published Journal PubMed Link
Gengan RM et al. Synthesis of sterigmatocystin derivatives and their biotransformation to aflatoxins by a blocked mutant of Aspergillus parasiticus. 1998-1999 Mycopathologia pmid:10481291
Pro MJ et al. Transformation of sterigmatocystin and O-methylsterigmatocystin by aflatoxigenic and nonaflatoxigenic field isolates of the Aspergillus flavus group. 1991 Mycopathologia pmid:1780000
Cary JW and Ehrlich KC Aflatoxigenicity in Aspergillus: molecular genetics, phylogenetic relationships and evolutionary implications. 2006 Mycopathologia pmid:16944284
Narasaiah KV et al. Biochemical analysis of oxidative stress in the production of aflatoxin and its precursor intermediates. 2006 Mycopathologia pmid:16944285
Hitokoto H et al. Chemically defined medium for high yields of sterigmatocystin. 1982 Mycopathologia pmid:7099245
Cary JW et al. Characterization of the Aspergillus ochraceoroseus aflatoxin/sterigmatocystin biosynthetic gene cluster. 2009 May-Jun Mycologia pmid:19537208
Cary JW et al. Characterization of aflatoxin-producing fungi outside of Aspergillus section Flavi. 2005 Mar-Apr Mycologia pmid:16396350
Cary JW et al. Functional and phylogenetic analysis of the Aspergillus ochraceoroseus aflQ (ordA) gene ortholog. 2012 Jul-Aug Mycologia pmid:22495451
Morita H et al. Mutagenicity of various chemicals including nickel and cobalt compounds in cultured mouse FM3A cells. 1991 Mutat. Res. pmid:1922156
Shahin MM The importance of analyzing structure-activity relationships in mutagenicity studies. 1989 Mutat. Res. pmid:2682227
Shahin MM Relationships between structure and mutagenic activity of environmental chemicals. 1987 Mutat. Res. pmid:3119999
Mori H et al. Genotoxic effects of a variety of sterigmatocystin-related compounds in the hepatocyte/DNA-repair test and the Salmonella microsome assay. 1986 Mutat. Res. pmid:3081801
Abdel-Wahhab MA et al. Adsorption of sterigmatocystin by montmorillonite and inhibition of its genotoxicity in the Nile tilapia fish (Oreachromis nilaticus). 2005 Mutat. Res. pmid:15781206
Pachter R and Steyn PS Quantum-chemical studies of aflatoxin B1, sterigmatocystin and versicolorin A, and a comparison with their mutagenic activity. 1985 May-Jun Mutat. Res. pmid:3923331
Reddy MV et al. Formation and persistence of sterigmatocystin--DNA adducts in rat liver determined via 32P-postlabeling analysis. 1985 Mutat. Res. pmid:4047087
Shimada T et al. Rat pulmonary microsomal cytochrome P-450 enzymes involved in the activation of procarcinogens. 1992 Mutat. Res. pmid:1281274
Chu FS Mycotoxins: food contamination, mechanism, carcinogenic potential and preventive measures. 1991 Mar-Apr Mutat. Res. pmid:2017214
Ueda N et al. Acute cytogenetic effect of sterigmatocystin on rat bone-marrow cells in vivo. 1984 Mutat. Res. pmid:6717486
Rodriguez-Arnaiz R and Aranda JH Metabolic activation of four drugs in the eye mosaic assay measuring principally mitotic recombination in Drosophila melanogaster: differences in strain susceptibility and route of exposure. 1994 Mutat. Res. pmid:7510026
Curry PT et al. Induction of sister-chromatid exchanges in vivo in mice by the mycotoxins sterigmatocystin and griseofulvin. 1984 Aug-Sep Mutat. Res. pmid:6472322
Ellard S et al. The use of genetically engineered V79 Chinese hamster cultures expressing rat liver CYP1A1, 1A2 and 2B1 cDNAs in micronucleus assays. 1991 Mutagenesis pmid:1800893
Leema G et al. Keratitis due to Aspergillus flavus: clinical profile, molecular identification of fungal strains and detection of aflatoxin production. 2010 Mol. Vis. pmid:20461152
Maggio-Hall LA et al. Fundamental contribution of beta-oxidation to polyketide mycotoxin production in planta. 2005 Mol. Plant Microbe Interact. pmid:16134890
Gao X et al. Inactivation of the lipoxygenase ZmLOX3 increases susceptibility of maize to Aspergillus spp. 2009 Mol. Plant Microbe Interact. pmid:19132874
Hicks J et al. RcoA has pleiotropic effects on Aspergillus nidulans cellular development. 2001 Mol. Microbiol. pmid:11260466
Jin Y et al. Requirement of spermidine for developmental transitions in Aspergillus nidulans. 2002 Mol. Microbiol. pmid:12410837
Fernandes M et al. Sequence-specific binding by Aspergillus nidulans AflR, a C6 zinc cluster protein regulating mycotoxin biosynthesis. 1998 Mol. Microbiol. pmid:9680223
Zhang YQ and Keller NP Blockage of methylcitrate cycle inhibits polyketide production in Aspergillus nidulans. 2004 Mol. Microbiol. pmid:15066039
Reyes-Dominguez Y et al. Heterochromatic marks are associated with the repression of secondary metabolism clusters in Aspergillus nidulans. 2010 Mol. Microbiol. pmid:20132440
Brodhagen M et al. Reciprocal oxylipin-mediated cross-talk in the Aspergillus-seed pathosystem. 2008 Mol. Microbiol. pmid:18181962
Bok JW et al. Secondary metabolic gene cluster silencing in Aspergillus nidulans. 2006 Mol. Microbiol. pmid:16968230
Tsitsigiannis DI and Keller NP Oxylipins act as determinants of natural product biosynthesis and seed colonization in Aspergillus nidulans. 2006 Mol. Microbiol. pmid:16420358
Yin WB et al. An Aspergillus nidulans bZIP response pathway hardwired for defensive secondary metabolism operates through aflR. 2012 Mol. Microbiol. pmid:22283524
Ramamoorthy V et al. veA-dependent RNA-pol II transcription elongation factor-like protein, RtfA, is associated with secondary metabolism and morphological development in Aspergillus nidulans. 2012 Mol. Microbiol. pmid:22783880
Soukup AA et al. Overexpression of the Aspergillus nidulans histone 4 acetyltransferase EsaA increases activation of secondary metabolite production. 2012 Mol. Microbiol. pmid:22882998
Lara-Rojas F et al. Aspergillus nidulans transcription factor AtfA interacts with the MAPK SakA to regulate general stress responses, development and spore functions. 2011 Mol. Microbiol. pmid:21320182
Schinko T et al. Transcriptome analysis of nitrate assimilation in Aspergillus nidulans reveals connections to nitric oxide metabolism. 2010 Mol. Microbiol. pmid:20969648
Bayram O et al. The protein kinase ImeB is required for light-mediated inhibition of sexual development and for mycotoxin production in Aspergillus nidulans. 2009 Mol. Microbiol. pmid:19210625
Feng X et al. cpsA regulates mycotoxin production, morphogenesis and cell wall biosynthesis in the fungus Aspergillus nidulans. 2017 Mol. Microbiol. pmid:28370587
Stinnett SM et al. Aspergillus nidulans VeA subcellular localization is dependent on the importin alpha carrier and on light. 2007 Mol. Microbiol. pmid:17163983
Saikia S and Scott B Functional analysis and subcellular localization of two geranylgeranyl diphosphate synthases from Penicillium paxilli. 2009 Mol. Genet. Genomics pmid:19529962
Olarte RA et al. Enhanced diversity and aflatoxigenicity in interspecific hybrids of Aspergillus flavus and Aspergillus parasiticus. 2015 Mol. Ecol. pmid:25773520
Shimizu M et al. Hydrolase controls cellular NAD, sirtuin, and secondary metabolites. 2012 Mol. Cell. Biol. pmid:22801369
Xing X et al. Involvement of MAPK and PI3K signaling pathway in sterigmatocystin-induced G2 phase arrest in human gastric epithelium cells. 2011 Mol Nutr Food Res pmid:21287681
Versilovskis A and De Saeger S Sterigmatocystin: occurrence in foodstuffs and analytical methods--an overview. 2010 Mol Nutr Food Res pmid:19998385
Zhang Y et al. Effects of sterigmatocystin on TNF-α, IL-6 and IL-12 expression in murine peripheral blood mononuclear cells and peritoneal macrophages in vivo. 2012 Mol Med Rep pmid:22344519
Tong PZ et al. Effects of sterigmatocystin on esophageal epithelium and experimental reflux esophagitis in rats. 2013 Mol Med Rep pmid:23942904
Volkov NV [The diagnosis of mycotoxin hepatitis in swine]. 1994 Sep-Oct Mikrobiol. Z. pmid:7834101
Yoshinari T et al. Dioctatin A is a strong inhibitor of aflatoxin production by Aspergillus parasiticus. 2007 Microbiology (Reading, Engl.) pmid:17660441
Yu HY et al. Functional analyses of heterotrimeric G protein G alpha and G beta subunits in Gibberella zeae. 2008 Microbiology (Reading, Engl.) pmid:18227243