| MeSH term | MeSH ID | Detail |
|---|---|---|
| Adenocarcinoma | D000230 | 166 associated lipids |
| Adenoma | D000236 | 40 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Cattle Diseases | D002418 | 24 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Esophageal Neoplasms | D004938 | 20 associated lipids |
| Gastritis | D005756 | 27 associated lipids |
| Hemangiosarcoma | D006394 | 4 associated lipids |
| Liver Diseases | D008107 | 31 associated lipids |
| Liver Neoplasms, Experimental | D008114 | 46 associated lipids |
STERIGMATOCYSTIN
STERIGMATOCYSTIN is a lipid of Polyketides (PK) class. Sterigmatocystin is associated with abnormalities such as CLEFT LIP, CONGENITAL HEALED, Exanthema and Lung diseases. The involved functions are known as sterigmatocystin biosynthetic process, Signal, secondary metabolic process, Biosynthetic Pathways and Anabolism. Sterigmatocystin often locates in Genital system, SAGA complex, Chromosomes, germ tube and Extracellular. The associated genes with STERIGMATOCYSTIN are Genome, Genes, vif, Homologous Gene, Genes, Regulator and Gene Clusters. The related lipids are hexanoic acid, Fatty Acids and Fatty Acids, Unsaturated.
Cross Reference
Introduction
To understand associated biological information of STERIGMATOCYSTIN, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with STERIGMATOCYSTIN?
STERIGMATOCYSTIN is suspected in CLEFT LIP, CONGENITAL HEALED, Exanthema, Lung diseases and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with STERIGMATOCYSTIN
PubChem Associated disorders and diseases
What pathways are associated with STERIGMATOCYSTIN
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with STERIGMATOCYSTIN?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with STERIGMATOCYSTIN?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with STERIGMATOCYSTIN?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with STERIGMATOCYSTIN?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with STERIGMATOCYSTIN?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with STERIGMATOCYSTIN
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Miller JD et al. | Inflammation-associated gene transcription and expression in mouse lungs induced by low molecular weight compounds from fungi from the built environment. | 2010 | Chem. Biol. Interact. | pmid:19818335 |
| Rand TG et al. | Effects of low molecular weight fungal compounds on inflammatory gene transcription and expression in mouse alveolar macrophages. | 2011 | Chem. Biol. Interact. | pmid:21356202 |
| Terao K et al. | The effects of O-acetylsterigmatocystin and related compounds on rat liver and cultured chicken embryonal liver cells. | 1975 | Chem. Biol. Interact. | pmid:1201614 |
| Baertschi SW et al. | Comparison of rates of enzymatic oxidation of aflatoxin B1, aflatoxin G1, and sterigmatocystin and activities of the epoxides in forming guanyl-N7 adducts and inducing different genetic responses. | 1989 Mar-Apr | Chem. Res. Toxicol. | pmid:2519710 |
| Cabaret O et al. | Metabolic detoxication pathways for sterigmatocystin in primary tracheal epithelial cells. | 2010 | Chem. Res. Toxicol. | pmid:20929267 |
| Krol ES | Metabolic detoxication pathways for sterigmatocystin in primary tracheal epithelial cells: structural identification of glutathione adducts. | 2011 | Chem. Res. Toxicol. | pmid:21866893 |
| Raney KD et al. | Oxidation of aflatoxins and sterigmatocystin by human liver microsomes: significance of aflatoxin Q1 as a detoxication product of aflatoxin B1. | 1992 Mar-Apr | Chem. Res. Toxicol. | pmid:1643250 |
| Bren U et al. | Guanine alkylation by the potent carcinogen aflatoxin B1: quantum chemical calculations. | 2007 | Chem. Res. Toxicol. | pmid:17630712 |
| Pfeiffer E et al. | Catechol formation: a novel pathway in the metabolism of sterigmatocystin and 11-methoxysterigmatocystin. | 2014 | Chem. Res. Toxicol. | pmid:25380456 |
| Slot JC and Rokas A | Horizontal transfer of a large and highly toxic secondary metabolic gene cluster between fungi. | 2011 | Curr. Biol. | pmid:21194949 |
| Le THT et al. | Protein O-mannosyltransferases are required for sterigmatocystin production and developmental processes in Aspergillus nidulans. | 2018 | Curr. Genet. | pmid:29492587 |
| Yu JH et al. | Conservation of structure and function of the aflatoxin regulatory gene aflR from Aspergillus nidulans and A. flavus. | 1996 | Curr. Genet. | pmid:8662194 |
| Wieser J et al. | Dominant mutations affecting both sporulation and sterigmatocystin biosynthesis in Aspergillus nidulans. | 1997 | Curr. Genet. | pmid:9339347 |
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| Wang X et al. | Inhibitors of neutrophil recruitment identified using transgenic zebrafish to screen a natural product library. | 2014 | Dis Model Mech | pmid:24291762 |
| Freitas-Silva O et al. | Tracing fungi secondary metabolites in Brazil nuts using LC-MS/MS. | 2011 | Drug Metab Lett | pmid:21722090 |
| Hicks JK et al. | Aspergillus sporulation and mycotoxin production both require inactivation of the FadA G alpha protein-dependent signaling pathway. | 1997 | EMBO J. | pmid:9305634 |
| Panackal AA et al. | Aspergillus ustus infections among transplant recipients. | 2006 | Emerging Infect. Dis. | pmid:16704776 |
| Kusunoki M et al. | Long-term administration of the fungus toxin, sterigmatocystin, induces intestinal metaplasia and increases the proliferative activity of PCNA, p53, and MDM2 in the gastric mucosa of aged Mongolian gerbils. | 2011 | Environ Health Prev Med | pmid:21431817 |
| Ito N et al. | Comparison of the promoting effects of various agents in induction of preneoplastic lesions in rat liver. | 1983 | Environ. Health Perspect. | pmid:6191977 |