STERIGMATOCYSTIN

STERIGMATOCYSTIN is a lipid of Polyketides (PK) class. Sterigmatocystin is associated with abnormalities such as CLEFT LIP, CONGENITAL HEALED, Exanthema and Lung diseases. The involved functions are known as sterigmatocystin biosynthetic process, Signal, secondary metabolic process, Biosynthetic Pathways and Anabolism. Sterigmatocystin often locates in Genital system, SAGA complex, Chromosomes, germ tube and Extracellular. The associated genes with STERIGMATOCYSTIN are Genome, Genes, vif, Homologous Gene, Genes, Regulator and Gene Clusters. The related lipids are hexanoic acid, Fatty Acids and Fatty Acids, Unsaturated.

Cross Reference

Introduction

To understand associated biological information of STERIGMATOCYSTIN, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with STERIGMATOCYSTIN?

STERIGMATOCYSTIN is suspected in CLEFT LIP, CONGENITAL HEALED, Exanthema, Lung diseases and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with STERIGMATOCYSTIN

MeSH term MeSH ID Detail
Weight Gain D015430 101 associated lipids
Xeroderma Pigmentosum D014983 6 associated lipids
Precancerous Conditions D011230 48 associated lipids
Lung Neoplasms D008175 171 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Liver Diseases D008107 31 associated lipids
Hemangiosarcoma D006394 4 associated lipids
Gastritis D005756 27 associated lipids
Esophageal Neoplasms D004938 20 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with STERIGMATOCYSTIN

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with STERIGMATOCYSTIN?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with STERIGMATOCYSTIN?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with STERIGMATOCYSTIN?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with STERIGMATOCYSTIN?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with STERIGMATOCYSTIN?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with STERIGMATOCYSTIN

Download all related citations
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Authors Title Published Journal PubMed Link
Shimada T and Guengerich FP Evidence for cytochrome P-450NF, the nifedipine oxidase, being the principal enzyme involved in the bioactivation of aflatoxins in human liver. 1989 Proc. Natl. Acad. Sci. U.S.A. pmid:2492107
Lee LS Metabolic precursor regulation of aflatoxin formation in toxigenic and non-toxigenic strains of Aspergillus flavus. 1989 Mycopathologia pmid:2515437
Gao W et al. Sterigmatocystin-induced oxidative DNA damage in human liver-derived cell line through lysosomal damage. 2015 Toxicol In Vitro pmid:25176419
Li M et al. An ultra-sensitive monoclonal antibody-based competitive enzyme immunoassay for sterigmatocystin in cereal and oil products. 2014 PLoS ONE pmid:25184275
Baertschi SW et al. Comparison of rates of enzymatic oxidation of aflatoxin B1, aflatoxin G1, and sterigmatocystin and activities of the epoxides in forming guanyl-N7 adducts and inducing different genetic responses. 1989 Mar-Apr Chem. Res. Toxicol. pmid:2519710
Wang J et al. Sterigmatocystin induces G1 arrest in primary human esophageal epithelial cells but induces G2 arrest in immortalized cells: key mechanistic differences in these two models. 2015 Arch. Toxicol. pmid:25294323
Fushimi Y et al. Measurement of sterigmatocystin concentrations in urine for monitoring the contamination of cattle feed. 2014 Toxins (Basel) pmid:25375815
Pfeiffer E et al. Catechol formation: a novel pathway in the metabolism of sterigmatocystin and 11-methoxysterigmatocystin. 2014 Chem. Res. Toxicol. pmid:25380456
Hossain MZ and Goto T Determination of sterigmatocystin in grain using gas chromatography-mass spectrometry with an on-column injector. 2015 Mycotoxin Res pmid:25394696
Bok JW et al. Illumina identification of RsrA, a conserved C2H2 transcription factor coordinating the NapA mediated oxidative stress signaling pathway in Aspergillus. 2014 BMC Genomics pmid:25416206