| MeSH term | MeSH ID | Detail |
|---|---|---|
| Adenocarcinoma | D000230 | 166 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Cattle Diseases | D002418 | 24 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Esophageal Neoplasms | D004938 | 20 associated lipids |
| Precancerous Conditions | D011230 | 48 associated lipids |
| Gastritis | D005756 | 27 associated lipids |
| Liver Diseases | D008107 | 31 associated lipids |
| Weight Gain | D015430 | 101 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
STERIGMATOCYSTIN
STERIGMATOCYSTIN is a lipid of Polyketides (PK) class. Sterigmatocystin is associated with abnormalities such as CLEFT LIP, CONGENITAL HEALED, Exanthema and Lung diseases. The involved functions are known as sterigmatocystin biosynthetic process, Signal, secondary metabolic process, Biosynthetic Pathways and Anabolism. Sterigmatocystin often locates in Genital system, SAGA complex, Chromosomes, germ tube and Extracellular. The associated genes with STERIGMATOCYSTIN are Genome, Genes, vif, Homologous Gene, Genes, Regulator and Gene Clusters. The related lipids are hexanoic acid, Fatty Acids and Fatty Acids, Unsaturated.
Cross Reference
Introduction
To understand associated biological information of STERIGMATOCYSTIN, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with STERIGMATOCYSTIN?
STERIGMATOCYSTIN is suspected in CLEFT LIP, CONGENITAL HEALED, Exanthema, Lung diseases and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with STERIGMATOCYSTIN
PubChem Associated disorders and diseases
What pathways are associated with STERIGMATOCYSTIN
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with STERIGMATOCYSTIN?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with STERIGMATOCYSTIN?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with STERIGMATOCYSTIN?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with STERIGMATOCYSTIN?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with STERIGMATOCYSTIN?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with STERIGMATOCYSTIN
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid: | ||||
| Essery JM et al. | Preparation and antitumor activities of some derivatives of 5-methoxysterigmatocystin. | 1976 | J. Med. Chem. | pmid:1003414 |
| Adams TH and Yu JH | Coordinate control of secondary metabolite production and asexual sporulation in Aspergillus nidulans. | 1998 | Curr. Opin. Microbiol. | pmid:10066549 |
| Zhang X et al. | [Effects of sterigmatocystin on ras p21 expression and ultrastructure of human lung fibroblasts in vitro]. | 1997 | Wei Sheng Yan Jiu | pmid:10325614 |
| Brown MP et al. | Genetic and molecular analysis of aflatoxin biosynthesis. | 1999 | Fungal Genet. Biol. | pmid:10328980 |
| Gengan RM et al. | Synthesis of sterigmatocystin derivatives and their biotransformation to aflatoxins by a blocked mutant of Aspergillus parasiticus. | 1998-1999 | Mycopathologia | pmid:10481291 |
| Butchko RA et al. | Aspergillus nidulans mutants defective in stc gene cluster regulation. | 1999 | Genetics | pmid:10511551 |
| Motomura M et al. | Cloning and characterization of the O-methyltransferase I gene (dmtA) from Aspergillus parasiticus associated with the conversions of demethylsterigmatocystin to sterigmatocystin and dihydrodemethylsterigmatocystin to dihydrosterigmatocystin in aflatoxin biosynthesis. | 1999 | Appl. Environ. Microbiol. | pmid:10543813 |
| Keller NP et al. | Requirement of monooxygenase-mediated steps for sterigmatocystin biosynthesis by Aspergillus nidulans. | 2000 | Appl. Environ. Microbiol. | pmid:10618248 |
| Sun X et al. | [Mutation of p53 gene in human fetal gastric mucosal cells by sterigmatocystin in vitro]. | 1998 | Wei Sheng Yan Jiu | pmid:10682599 |
| Klich MA et al. | Molecular and physiological aspects of aflatoxin and sterigmatocystin biosynthesis by Aspergillus tamarii and A. ochraceoroseus. | 2000 | Appl. Microbiol. Biotechnol. | pmid:10855723 |
| Cary JW et al. | Generation of aflR disruption mutants of Aspergillus parasiticus. | 2000 | Appl. Microbiol. Biotechnol. | pmid:10919326 |
| Wogan GN | Mycotoxins. | 1975 | Annu Rev Pharmacol | pmid:1096795 |
| Xie TX et al. | Absence of p53-mediated G1 arrest with induction of MDM2 in sterigmatocystin-treated cells. | 2000 | Int. J. Oncol. | pmid:10995885 |
| Reiss J | [Biosynthetic pathways of important mycotoxins]. | 1978 | Z. Allg. Mikrobiol. | pmid:111430 |
| Shimizu K and Keller NP | Genetic involvement of a cAMP-dependent protein kinase in a G protein signaling pathway regulating morphological and chemical transitions in Aspergillus nidulans. | 2001 | Genetics | pmid:11156981 |
| Hicks J et al. | RcoA has pleiotropic effects on Aspergillus nidulans cellular development. | 2001 | Mol. Microbiol. | pmid:11260466 |
| Klich M et al. | A new sterigmatocystin-producing Emericella variant from agricultural desert soils. | 2001 | Syst. Appl. Microbiol. | pmid:11403392 |
| Steyn M and Rabie CJ | Production of sterigmatocystin. | 1975 | J Assoc Off Anal Chem | pmid:1141192 |
| D'Souza CA et al. | Characterization of the role of the FluG protein in asexual development of Aspergillus nidulans. | 2001 | Genetics | pmid:11454752 |
| Dezotti NO and Zucchi TM | Identification of Aspergillus nidulans genes essential for the accumulation of sterigmatocystin. | 2001 | Fungal Genet. Biol. | pmid:11686675 |
| Stich HF and Laishes BA | The response of Xeroderma pigmentosum cells and controls to the activated mycotoxins, aflatoxins and sterigmatocystin. | 1975 | Int. J. Cancer | pmid:1171827 |
| Sivakumar V et al. | Lipid peroxidation as a possible secondary mechanism of sterigmatocystin toxicity. | 2001 | Hum Exp Toxicol | pmid:11727790 |
| Bradner WT et al. | Fermentation, isolation, and antitumor activity of sterigmatocystins. | 1975 | Antimicrob. Agents Chemother. | pmid:1180542 |
| Halls NA and Ayres JC | Factors affecting the production of sterigmatocystin in semisynthetic media. | 1975 | Appl Microbiol | pmid:1190766 |
| Lafont P and Debeaupuis JP | [Effect of sterigmatocystin on the toxinogenesis of the Aspergillus flavus group]. | 1979 | Mycopathologia | pmid:119164 |
| Udwary DW et al. | Synthesis of 11-hydroxyl O-methylsterigmatocystin and the role of a cytochrome P-450 in the final step of aflatoxin biosynthesis. | 2002 | J. Am. Chem. Soc. | pmid:11996570 |
| Terao K et al. | The effects of O-acetylsterigmatocystin and related compounds on rat liver and cultured chicken embryonal liver cells. | 1975 | Chem. Biol. Interact. | pmid:1201614 |
| Engelhart S et al. | Occurrence of toxigenic Aspergillus versicolor isolates and sterigmatocystin in carpet dust from damp indoor environments. | 2002 | Appl. Environ. Microbiol. | pmid:12147486 |
| Ma F et al. | Inhibition of vacuolation toxin activity of Helicobacter pylori by iodine, nitrite and potentiation by sodium chloride, sterigmatocystin and fluoride. | 2002 | Toxicol In Vitro | pmid:12206820 |
| Calvo AM et al. | Relationship between secondary metabolism and fungal development. | 2002 | Microbiol. Mol. Biol. Rev. | pmid:12208999 |
| Sun XM et al. | Effects of sterigmatocystin, deoxynivalenol and aflatoxin G1 on apoptosis of human peripheral blood lymphocytes in vitro. | 2002 | Biomed. Environ. Sci. | pmid:12244755 |
| Kononenko GP et al. | [Comparative characteristics of immunoreagents based on aflatoxin B1 hemiacetals and sterigmatocystine]. | 2002 Sep-Oct | Prikl. Biokhim. Mikrobiol. | pmid:12391761 |
| Lee LW et al. | Function of native OmtA in vivo and expression and distribution of this protein in colonies of Aspergillus parasiticus. | 2002 | Appl. Environ. Microbiol. | pmid:12406770 |
| Jin Y et al. | Requirement of spermidine for developmental transitions in Aspergillus nidulans. | 2002 | Mol. Microbiol. | pmid:12410837 |
| Frank HK | [Marginals to mycotoxin research (author's transl)]. | 1975 | Arzneimittelforschung | pmid:1243052 |
| Joshi BK et al. | Bioactive natural products from a sclerotium-colonizing isolate of Humicola fuscoatra. | 2002 | J. Nat. Prod. | pmid:12444718 |
| Duracková Z et al. | Bioautographic detection of mycotoxins on thin-layer chromatograms. | 1976 | J. Chromatogr. | pmid:1245565 |
| Sullivan G et al. | Thin-layer chromatographic separation of sterigmatocystin, 5-methoxy-sterigmatocystin and O-methylsterigmatocystin. | 1976 | J. Chromatogr. | pmid:1245589 |
| Kingston DG and Chen PN | High-performance liquid chromatography of sterigmatocystin and other metabolites of Aspergillus versicolor. | 1976 | J. Chromatogr. | pmid:1254677 |
| Huang X et al. | [Effects of sterigmatocystin on interleukin-2 secretion of human peripheral blood mononuclear cells in vitro]. | 2002 | Wei Sheng Yan Jiu | pmid:12561545 |
| Kononenko GP et al. | [Specific features of albumin interactions with hemiacetals of aflatoxins and sterigmatocystin]. | 2003 Jan-Feb | Prikl. Biokhim. Mikrobiol. | pmid:12625053 |
| Atalla MM et al. | Mycotoxin production in wheat grains by different Aspergilli in relation to different relative humidities and storage periods. | 2003 | Nahrung | pmid:12653428 |
| Fujii K et al. | Tumor induction by a single subcutaneous injection of sterigmatocystin in newborn mice. | 1976 | Cancer Res. | pmid:1268822 |
| Reiss J | Prevention of the formation of mycotoxins in whole wheat bread by citric acid and lactic acid. (Mycotoxins in foodstuffs. IX). | 1976 | Experientia | pmid:1269599 |
| Reijula K and Tuomi T | Mycotoxins of aspergilli: exposure and health effects. | 2003 | Front. Biosci. | pmid:12700107 |
| Cao W et al. | [Mutation of p53 and Ki-ras gene in human fetal lung fibroblast cells in vitro by sterigmatocystin]. | 2000 | Wei Sheng Yan Jiu | pmid:12725069 |
| Lemieszek-Chodorowska K | [Identification and semiquantitative determination of ochratoxins A and B, sterigmatocystin and aflatoxin B-1]. | 1976 | Rocz Panstw Zakl Hig | pmid:1273420 |
| Ma F et al. | Long-term treatment with sterigmatocystin, a fungus toxin, enhances the development of intestinal metaplasia of gastric mucosa in Helicobacter pylori-infected Mongolian gerbils. | 2003 | Scand. J. Gastroenterol. | pmid:12739707 |
| Yu J et al. | Cloning and functional expression of an esterase gene in Aspergillus parasitcus. | 2002 | Mycopathologia | pmid:12749588 |