STERIGMATOCYSTIN

STERIGMATOCYSTIN is a lipid of Polyketides (PK) class. Sterigmatocystin is associated with abnormalities such as CLEFT LIP, CONGENITAL HEALED, Exanthema and Lung diseases. The involved functions are known as sterigmatocystin biosynthetic process, Signal, secondary metabolic process, Biosynthetic Pathways and Anabolism. Sterigmatocystin often locates in Genital system, SAGA complex, Chromosomes, germ tube and Extracellular. The associated genes with STERIGMATOCYSTIN are Genome, Genes, vif, Homologous Gene, Genes, Regulator and Gene Clusters. The related lipids are hexanoic acid, Fatty Acids and Fatty Acids, Unsaturated.

Cross Reference

Introduction

To understand associated biological information of STERIGMATOCYSTIN, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with STERIGMATOCYSTIN?

STERIGMATOCYSTIN is suspected in CLEFT LIP, CONGENITAL HEALED, Exanthema, Lung diseases and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with STERIGMATOCYSTIN

MeSH term MeSH ID Detail
Adenocarcinoma D000230 166 associated lipids
Lung Neoplasms D008175 171 associated lipids
Cattle Diseases D002418 24 associated lipids
Body Weight D001835 333 associated lipids
Esophageal Neoplasms D004938 20 associated lipids
Precancerous Conditions D011230 48 associated lipids
Gastritis D005756 27 associated lipids
Liver Diseases D008107 31 associated lipids
Weight Gain D015430 101 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Per page 10 20 | Total 14

PubChem Associated disorders and diseases

What pathways are associated with STERIGMATOCYSTIN

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with STERIGMATOCYSTIN?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with STERIGMATOCYSTIN?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with STERIGMATOCYSTIN?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with STERIGMATOCYSTIN?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with STERIGMATOCYSTIN?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with STERIGMATOCYSTIN

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Authors Title Published Journal PubMed Link
Liu CH et al. [The secondary metabolites of the HS-3 Alternaria sp. fungus associated with holothurians]. 2010 Zhong Yao Cai pmid:21548363
Schwelm A and Bradshaw RE Genetics of dothistromin biosynthesis of Dothistroma septosporum: an update. 2010 Toxins (Basel) pmid:22069571
Duran R et al. Role of the osmotic stress regulatory pathway in morphogenesis and secondary metabolism in filamentous fungi. 2010 Toxins (Basel) pmid:22069590
Bartoszewska M et al. The significance of peroxisomes in secondary metabolite biosynthesis in filamentous fungi. 2011 Biotechnol. Lett. pmid:21660569
Jiang J et al. Involvement of a velvet protein FgVeA in the regulation of asexual development, lipid and secondary metabolisms and virulence in Fusarium graminearum. 2011 PLoS ONE pmid:22140571
Cai S et al. Sterigmatocystins from the deep-sea-derived fungus Aspergillus versicolor. 2011 J. Antibiot. pmid:21119680
Baidya S et al. Role of nitric oxide and flavohemoglobin homolog genes in Aspergillus nidulans sexual development and mycotoxin production. 2011 Appl. Environ. Microbiol. pmid:21642398
Slot JC and Rokas A Horizontal transfer of a large and highly toxic secondary metabolic gene cluster between fungi. 2011 Curr. Biol. pmid:21194949
Kusunoki M et al. Long-term administration of the fungus toxin, sterigmatocystin, induces intestinal metaplasia and increases the proliferative activity of PCNA, p53, and MDM2 in the gastric mucosa of aged Mongolian gerbils. 2011 Environ Health Prev Med pmid:21431817
Matasyoh JC et al. Larvicidal activity of metabolites from the endophytic Podospora sp. against the malaria vector Anopheles gambiae. 2011 Parasitol. Res. pmid:20922412
Xing X et al. Involvement of MAPK and PI3K signaling pathway in sterigmatocystin-induced G2 phase arrest in human gastric epithelium cells. 2011 Mol Nutr Food Res pmid:21287681
Zeng H et al. Conversion of 11-hydroxy-O-methylsterigmatocystin to aflatoxin G1 in Aspergillus parasiticus. 2011 Appl. Microbiol. Biotechnol. pmid:21153813
Rand TG et al. Effects of low molecular weight fungal compounds on inflammatory gene transcription and expression in mouse alveolar macrophages. 2011 Chem. Biol. Interact. pmid:21356202
Tóth V et al. Polyphasic characterization of "Aspergillus nidulans var. roseus" ATCC 58397. 2011 Folia Microbiol. (Praha) pmid:21858538
Krol ES Metabolic detoxication pathways for sterigmatocystin in primary tracheal epithelial cells: structural identification of glutathione adducts. 2011 Chem. Res. Toxicol. pmid:21866893
Cabaret O et al. Contribution of uniformly 13C-enriched sterigmatocystin to the study of its pulmonary metabolism. 2011 Rapid Commun. Mass Spectrom. pmid:21913247
Nützmann HW et al. Bacteria-induced natural product formation in the fungus Aspergillus nidulans requires Saga/Ada-mediated histone acetylation. 2011 Proc. Natl. Acad. Sci. U.S.A. pmid:21825172
Laverty G et al. The potential of antimicrobial peptides as biocides. 2011 Int J Mol Sci pmid:22072905
Yunus AW et al. Aflatoxin B(1) in affecting broiler's performance, immunity, and gastrointestinal tract: a review of history and contemporary issues. 2011 Toxins (Basel) pmid:22069726
Abdel-Hadi AM et al. Control of aflatoxin production of Aspergillus flavus and Aspergillus parasiticus using RNA silencing technology by targeting aflD (nor-1) gene. 2011 Toxins (Basel) pmid:22069731
Bansal J et al. Surveys of rice sold in Canada for aflatoxins, ochratoxin A and fumonisins. 2011 Food Addit Contam Part A Chem Anal Control Expo Risk Assess pmid:21623501
Houbraken J and Samson RA Phylogeny of Penicillium and the segregation of Trichocomaceae into three families. 2011 Stud. Mycol. pmid:22308045
Tisch D et al. The phosducin-like protein PhLP1 impacts regulation of glycoside hydrolases and light response in Trichoderma reesei. 2011 BMC Genomics pmid:22182583
Kattke MD et al. FRET-based quantum dot immunoassay for rapid and sensitive detection of Aspergillus amstelodami. 2011 Sensors (Basel) pmid:22163961
Zheng P et al. Genome sequence of the insect pathogenic fungus Cordyceps militaris, a valued traditional Chinese medicine. 2011 Genome Biol. pmid:22112802
Wilkinson JR et al. Expression profiling of non-aflatoxigenic Aspergillus parasiticus mutants obtained by 5-azacytosine treatment or serial mycelial transfer. 2011 Toxins (Basel) pmid:22069749
Nasmith CG et al. Tri6 is a global transcription regulator in the phytopathogen Fusarium graminearum. 2011 PLoS Pathog. pmid:21980289
Samson RA et al. New taxa in Aspergillus section Usti. 2011 Stud. Mycol. pmid:21892244
Varga J et al. Two new aflatoxin producing species, and an overview of Aspergillus section Flavi. 2011 Stud. Mycol. pmid:21892243
Boenisch MJ and Schäfer W Fusarium graminearum forms mycotoxin producing infection structures on wheat. 2011 BMC Plant Biol. pmid:21798058
Pauly JL and Paszkiewicz G Cigarette smoke, bacteria, mold, microbial toxins, and chronic lung inflammation. 2011 J Oncol pmid:21772847
Trienens M and Rohlfs M Experimental evolution of defense against a competitive mold confers reduced sensitivity to fungal toxins but no increased resistance in Drosophila larvae. 2011 BMC Evol. Biol. pmid:21756302
Khaldi N and Wolfe KH Evolutionary Origins of the Fumonisin Secondary Metabolite Gene Cluster in Fusarium verticillioides and Aspergillus niger. 2011 Int J Evol Biol pmid:21716743
Gerbaldo GA et al. Surveillance of Aflatoxin and Microbiota Related to Brewer's Grain Destined for Swine Feed in Argentina. 2011 Vet Med Int pmid:21547231
Lara-Rojas F et al. Aspergillus nidulans transcription factor AtfA interacts with the MAPK SakA to regulate general stress responses, development and spore functions. 2011 Mol. Microbiol. pmid:21320182
Mathioni SM et al. Transcriptome profiling of the rice blast fungus during invasive plant infection and in vitro stresses. 2011 BMC Genomics pmid:21247492
Freitas-Silva O et al. Tracing fungi secondary metabolites in Brazil nuts using LC-MS/MS. 2011 Drug Metab Lett pmid:21722090
Cai GH et al. Fungal DNA, allergens, mycotoxins and associations with asthmatic symptoms among pupils in schools from Johor Bahru, Malaysia. 2011 Pediatr Allergy Immunol pmid:21457336
Rank C et al. Distribution of sterigmatocystin in filamentous fungi. 2011 Apr-May Fungal Biol pmid:21530923
Huţanaşu C et al. [High levels of sterigmatocystin in patients with chronic liver diseases]. 2011 Jan-Mar Rev Med Chir Soc Med Nat Iasi pmid:21688557
Bromann K et al. Identification and characterization of a novel diterpene gene cluster in Aspergillus nidulans. 2012 PLoS ONE pmid:22506079
Cottier F and Mühlschlegel FA Communication in fungi. 2012 Int J Microbiol pmid:21961006
Gerke J et al. Fungal S-adenosylmethionine synthetase and the control of development and secondary metabolism in Aspergillus nidulans. 2012 Fungal Genet. Biol. pmid:22561085
Wartenberg D et al. Proteome analysis of the farnesol-induced stress response in Aspergillus nidulans--The role of a putative dehydrin. 2012 J Proteomics pmid:22634043
Yin WB et al. An Aspergillus nidulans bZIP response pathway hardwired for defensive secondary metabolism operates through aflR. 2012 Mol. Microbiol. pmid:22283524
Zhang Y et al. Effects of sterigmatocystin on TNF-α, IL-6 and IL-12 expression in murine peripheral blood mononuclear cells and peritoneal macrophages in vivo. 2012 Mol Med Rep pmid:22344519
Chang PK et al. Deletion of the Aspergillus flavus orthologue of A. nidulans fluG reduces conidiation and promotes production of sclerotia but does not abolish aflatoxin biosynthesis. 2012 Appl. Environ. Microbiol. pmid:22904054
Shimizu M et al. Hydrolase controls cellular NAD, sirtuin, and secondary metabolites. 2012 Mol. Cell. Biol. pmid:22801369
Kocić-Tanackov S et al. Effects of onion (Allium cepa L.) and garlic (Allium sativum L.) essential oils on the Aspergillus versicolor growth and sterigmatocystin production. 2012 J. Food Sci. pmid:22497489
Liu Y et al. Sterigmatocystin alters the number of FoxP3+ regulatory T cells and plasmacytoid dendritic cells in BALB/c mice. 2012 Food Chem. Toxicol. pmid:22429820
Jakšić D et al. Cytotoxicity and genotoxicity of versicolorins and 5-methoxysterigmatocystin in A549 cells. 2012 Arch. Toxicol. pmid:22648070
Laskowski-Peak MC et al. VEA1 is required for cleistothecial formation and virulence in Histoplasma capsulatum. 2012 Fungal Genet. Biol. pmid:22841690
Ramamoorthy V et al. veA-dependent RNA-pol II transcription elongation factor-like protein, RtfA, is associated with secondary metabolism and morphological development in Aspergillus nidulans. 2012 Mol. Microbiol. pmid:22783880
Veršilovskis A and Bartkevičs V Stability of sterigmatocystin during the bread making process and its occurrence in bread from the Latvian market. 2012 Mycotoxin Res pmid:23606050
Soukup AA et al. Overexpression of the Aspergillus nidulans histone 4 acetyltransferase EsaA increases activation of secondary metabolite production. 2012 Mol. Microbiol. pmid:22882998
Rodrigues P et al. Aflatoxigenic fungi and aflatoxins in Portuguese almonds. 2012 ScientificWorldJournal pmid:22666128
Wu D et al. ChLae1 and ChVel1 regulate T-toxin production, virulence, oxidative stress response, and development of the maize pathogen Cochliobolus heterostrophus. 2012 PLoS Pathog. pmid:22383877
Gauthier T et al. Trypacidin, a spore-borne toxin from Aspergillus fumigatus, is cytotoxic to lung cells. 2012 PLoS ONE pmid:22319557
Thrasher JD et al. A water-damaged home and health of occupants: a case study. 2012 J Environ Public Health pmid:22220187
Reyes-Dominguez Y et al. Heterochromatin influences the secondary metabolite profile in the plant pathogen Fusarium graminearum. 2012 Fungal Genet. Biol. pmid:22100541
Warth B et al. Quantitation of mycotoxins in food and feed from Burkina Faso and Mozambique using a modern LC-MS/MS multitoxin method. 2012 J. Agric. Food Chem. pmid:22835072
Levin RE PCR detection of aflatoxin producing fungi and its limitations. 2012 Int. J. Food Microbiol. pmid:22445201
Peitzsch M et al. Remediation of mould damaged building materials--efficiency of a broad spectrum of treatments. 2012 J Environ Monit pmid:22286589
Chettri P et al. The veA gene of the pine needle pathogen Dothistroma septosporum regulates sporulation and secondary metabolism. 2012 Fungal Genet. Biol. pmid:22227160
Cary JW et al. Functional and phylogenetic analysis of the Aspergillus ochraceoroseus aflQ (ordA) gene ortholog. 2012 Jul-Aug Mycologia pmid:22495451
Jurjević Z et al. Sterigmatocystin production by nine newly described Aspergillus species in section Versicolores grown on two different media. 2013 Mycotoxin Res pmid:23417508
Ezekiel CN et al. Fungal and mycotoxin assessment of dried edible mushroom in Nigeria. 2013 Int. J. Food Microbiol. pmid:23454813
Shantappa S et al. Role of the zinc finger transcription factor SltA in morphogenesis and sterigmatocystin biosynthesis in the fungus Aspergillus nidulans. 2013 PLoS ONE pmid:23840895
Mueller A et al. Individual and combined effects of mycotoxins from typical indoor moulds. 2013 Toxicol In Vitro pmid:23851004
Wang J et al. Role of hMLH1 in sterigmatocystin-induced Gâ‚‚ phase arrest in human esophageal epithelial Het-1A cells in vitro. 2013 Toxicol. Lett. pmid:23296099
Zhang D et al. Sterigmatocystin-induced DNA damage triggers G2 arrest via an ATM/p53-related pathway in human gastric epithelium GES-1 cells in vitro. 2013 PLoS ONE pmid:23705030
Tong PZ et al. Effects of sterigmatocystin on esophageal epithelium and experimental reflux esophagitis in rats. 2013 Mol Med Rep pmid:23942904
Xu YM et al. Secoemestrin D, a cytotoxic epitetrathiodioxopiperizine, and emericellenes A-E, five sesterterpenoids from Emericella sp. AST0036, a fungal endophyte of Astragalus lentiginosus1. 2013 J. Nat. Prod. pmid:24251417
Nützmann HW et al. Distinct amino acids of histone H3 control secondary metabolism in Aspergillus nidulans. 2013 Appl. Environ. Microbiol. pmid:23892751
Wang X et al. Inhibitors of neutrophil recruitment identified using transgenic zebrafish to screen a natural product library. 2014 Dis Model Mech pmid:24291762
Almeida C et al. Chemical and bioactive natural products from Microthyriaceae sp., an endophytic fungus from a tropical grass. 2014 Lett. Appl. Microbiol. pmid:24612068
Pfeiffer E et al. Catechol formation: a novel pathway in the metabolism of sterigmatocystin and 11-methoxysterigmatocystin. 2014 Chem. Res. Toxicol. pmid:25380456
Sasaki R et al. Development of an analytical method for the determination of sterigmatocystin in grains using LCMS after immunoaffinity column purification. 2014 Mycotoxin Res pmid:24696064
Zheng R et al. Simultaneous determination of aflatoxin B(1), B(2), G(1), G(2), ochratoxin A, and sterigmatocystin in traditional Chinese medicines by LC-MS-MS. 2014 Anal Bioanal Chem pmid:24658469
Huang S et al. Impairment of cell cycle progression by sterigmatocystin in human pulmonary cells in vitro. 2014 Food Chem. Toxicol. pmid:24480041
Song F et al. Three new sterigmatocystin analogues from marine-derived fungus Aspergillus versicolor MF359. 2014 Appl. Microbiol. Biotechnol. pmid:24458562
Cabaret O et al. Metabolic detoxification pathways for 5-methoxy-sterigmatocystin in primary tracheal epithelial cells. 2014 Xenobiotica pmid:23756242
Bok JW et al. Illumina identification of RsrA, a conserved C2H2 transcription factor coordinating the NapA mediated oxidative stress signaling pathway in Aspergillus. 2014 BMC Genomics pmid:25416206
Fushimi Y et al. Measurement of sterigmatocystin concentrations in urine for monitoring the contamination of cattle feed. 2014 Toxins (Basel) pmid:25375815
Li M et al. An ultra-sensitive monoclonal antibody-based competitive enzyme immunoassay for sterigmatocystin in cereal and oil products. 2014 PLoS ONE pmid:25184275
Lee MK et al. NsdD is a key repressor of asexual development in Aspergillus nidulans. 2014 Genetics pmid:24532783
Anninou N et al. Mycotoxins' activity at toxic and sub-toxic concentrations: differential cytotoxic and genotoxic effects of single and combined administration of sterigmatocystin, ochratoxin A and citrinin on the hepatocellular cancer cell line Hep3B. 2014 Int J Environ Res Public Health pmid:24514428
Marley E et al. Analysis of sterigmatocystin in cereals, animal feed, seeds, beer and cheese by immunoaffinity column clean-up and HPLC and LC-MS/MS quantification. 2015 Food Addit Contam Part A Chem Anal Control Expo Risk Assess pmid:26515281
Biancardi A and Dall'Asta C Determination of sterigmatocystin in feed by LC-MS/MS. 2015 Food Addit Contam Part A Chem Anal Control Expo Risk Assess pmid:26471726
Olarte RA et al. Enhanced diversity and aflatoxigenicity in interspecific hybrids of Aspergillus flavus and Aspergillus parasiticus. 2015 Mol. Ecol. pmid:25773520
Wu YZ et al. The furofuran-ring selectivity, hydrogen peroxide-production and low Km value are the three elements for highly effective detoxification of aflatoxin oxidase. 2015 Food Chem. Toxicol. pmid:25533793
Hossain MZ and Goto T Determination of sterigmatocystin in grain using gas chromatography-mass spectrometry with an on-column injector. 2015 Mycotoxin Res pmid:25394696
Wang J et al. Sterigmatocystin induces G1 arrest in primary human esophageal epithelial cells but induces G2 arrest in immortalized cells: key mechanistic differences in these two models. 2015 Arch. Toxicol. pmid:25294323
Gao W et al. Sterigmatocystin-induced oxidative DNA damage in human liver-derived cell line through lysosomal damage. 2015 Toxicol In Vitro pmid:25176419
Moore GG et al. Draft Genome Sequences of Two Closely Related Aflatoxigenic Aspergillus Species Obtained from the Ivory Coast. 2015 Genome Biol Evol pmid:26637470
Bryant BR et al. Acute hepatic necrosis and death in a subadult southern white rhinoceros (Ceratotherium simum) associated with exposure to sterigmatocystin in forage contaminated with Aspergillus nidulans. 2016 Aust. Vet. J. pmid:27785798
Despot DJ et al. Species diversity and cytotoxic potency of airborne sterigmatocystin-producing Aspergilli from the section Versicolores. 2016 Sci. Total Environ. pmid:27100010
Liu S et al. Determination of Sterigmatocystin in Infant Cereals from Hangzhou, China. 2016 J AOAC Int pmid:27330032
Zouaoui N et al. Cytotoxic effects induced by patulin, sterigmatocystin and beauvericin on CHO-K1 cells. 2016 Food Chem. Toxicol. pmid:26802678
Xu L et al. One-pot synthesis of carbon dots-embedded molecularly imprinted polymer for specific recognition of sterigmatocystin in grains. 2016 Biosens Bioelectron pmid:26544869