AFBI

AFBI is a lipid of Polyketides (PK) class. Afbi is associated with abnormalities such as Pyotraumatic dermatitis, Infection, Hepatitis, Liver diseases and Hepatitis B. The involved functions are known as Immune response, Mutation, Anabolism, Metabolic Inhibition and Increased Sensitivy. Afbi often locates in Body tissue, Hepatic, Cytoplasm, Blood and Micronucleus. The associated genes with AFBI are TP53 gene, Genome, Transgenes, FATE1 gene and MANEA gene. The related lipids are Lipopolysaccharides, Lipid Peroxides, 1-(2-cyano-3,12-dioxooleana-1,9-dien-28-oyl) imidazole and Liposomes.

Cross Reference

Introduction

To understand associated biological information of AFBI, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with AFBI?

AFBI is suspected in Infection, Liver diseases, Hepatitis, Hepatitis B, Simian B disease, Viral hepatitis and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with AFBI

MeSH term MeSH ID Detail
Sarcoma, Experimental D012513 13 associated lipids
Adenocarcinoma D000230 166 associated lipids
Pain D010146 64 associated lipids
Lung Neoplasms D008175 171 associated lipids
Kidney Neoplasms D007680 29 associated lipids
Liver Neoplasms D008113 8 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Cattle Diseases D002418 24 associated lipids
Fatty Liver D005234 48 associated lipids
Body Weight D001835 333 associated lipids
Per page 10 20 50 100 | Total 69

PubChem Associated disorders and diseases

What pathways are associated with AFBI

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with AFBI?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with AFBI?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with AFBI?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with AFBI?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with AFBI?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with AFBI

Download all related citations
Per page 10 20 50 100 | Total 3682
Authors Title Published Journal PubMed Link
Sekijima M et al. Enhancement of glutathione S-transferase placental-form positive liver cell foci development by microcystin-LR in aflatoxin B1-initiated rats. 1999 Carcinogenesis pmid:9934864
Liu DL et al. Armillariella tabescen enzymatic detoxification of aflatoxin B1. Part III. Immobilized enzymatic detoxification. 1998 Ann. N. Y. Acad. Sci. pmid:9928145
Liu DL et al. Armillariella tabescen enzymatic detoxification of aflatoxin B1 (Part II). 1998 Ann. N. Y. Acad. Sci. pmid:9928144
Yao DS et al. Screening of the fungus whose multienzyme system has catalytic detoxification activity towards aflatoxin B1 (Part I). 1998 Ann. N. Y. Acad. Sci. pmid:9928143
Ross MK et al. 5-Methylcytosine in CpG sites and the reactivity of nearest neighboring guanines toward the carcinogen aflatoxin B1-8,9-epoxide. 1999 Biochem. Biophys. Res. Commun. pmid:9920742
Ha TG and Kim ND 2-(allylthio)pyrazine inhibition of aflatoxin B1-induced hepatotoxicity in rats: inhibition of cytochrome P450 2B- and 3A2-mediated bioactivation. 1998 Res. Commun. Mol. Pathol. Pharmacol. pmid:9920347
Qin G et al. Enhancement of aflatoxin B1-induced enzyme altered hepatic foci in rats by treatment with carbon tetrachloride. 1998 Exp. Mol. Med. pmid:9894147
Denissenko MF et al. The p53 codon 249 mutational hotspot in hepatocellular carcinoma is not related to selective formation or persistence of aflatoxin B1 adducts. 1998 Oncogene pmid:9881702
Marzilli LA et al. Mass spectral identification and positional mapping of aflatoxin B1-guanine adducts in oligonucleotides. 1998 J. Am. Soc. Mass Spectrom. pmid:9879377
Raj HG et al. Aflatoxin B1-induced micronuclei and cell cycle alterations in lung and bone marrow cells and their modulation by Piper argyrophyllum extract. 1998 Teratog., Carcinog. Mutagen. pmid:9876014
D'Souza DH and Brackett RE The role of trace metal ions in aflatoxin B1 degradation by Flavobacterium aurantiacum. 1998 J. Food Prot. pmid:9874346
Moon EY et al. Aflatoxin B1-induced suppression of nitric oxide production in murine peritoneal macrophages. 1998 J. Toxicol. Environ. Health Part A pmid:9860325
Raj HG et al. Mechanism of biochemical action of substituted 4-methylbenzopyran-2-ones. Part II: Mechanism-based inhibition of rat liver microsome-mediated aflatoxin B1-DNA binding by the candidate antimutagen 7,8-diacetoxy-4-methylcoumarin. 1998 Bioorg. Med. Chem. pmid:9839019
Ali-Vehmas T et al. Measurement of antibacterial activities of T-2 toxin, deoxynivalenol, ochratoxin A, aflatoxin B1 and fumonisin B1 using microtitration tray-based turbidimetric techniques. 1998 Zentralbl Veterinarmed A pmid:9838857
Yu J et al. Characterization of the critical amino acids of an Aspergillus parasiticus cytochrome P-450 monooxygenase encoded by ordA that is involved in the biosynthesis of aflatoxins B1, G1, B2, and G2. 1998 Appl. Environ. Microbiol. pmid:9835571
Sluis-Cremer N et al. Aflatoxin B1 and sulphobromophthalein binding to the dimeric human glutathione S-transferase A1-1: a fluorescence spectroscopic analysis. 1998 Eur. J. Biochem. pmid:9826190
Belokrylov GA et al. [Parameters of granulocyte phagocytic activity and their immunocorrection during chronic aflatoxicosis B1 and benzene intoxication]. 1998 Biull Eksp Biol Med pmid:9825143
Kiefer F and Wiebel FJ Caffeine potentiates the formation of micronuclei caused by environmental chemical carcinogens in V79 Chinese hamster cells. 1998 Toxicol. Lett. pmid:9820657
Abulu EO et al. Preliminary investigation on aflatoxin in cord blood of jaundiced neonates. 1998 Jul-Sep West Afr J Med pmid:9814089
Manson MM et al. Chemoprevention of aflatoxin B1-induced carcinogenesis by indole-3-carbinol in rat liver--predicting the outcome using early biomarkers. 1998 Carcinogenesis pmid:9806166
Stĕtinová V et al. Changes in the gastrointestinal tract, cardiovascular function and some drug metabolizing processes in rats and guinea-pigs intoxicated with aflatoxin B1. 1998 Mar-Apr Pol J Pharmacol pmid:9798265
Schiller F et al. Liver fibrosis in guinea pigs experimentally induced by combined copper and aflatoxin application. 1998 Exp. Toxicol. Pathol. pmid:9784033
Atroshi F et al. Effects of tamoxifen, melatonin, coenzyme Q10, and L-carnitine supplementation on bacterial growth in the presence of mycotoxins. 1998 Pharmacol. Res. pmid:9774492
Van Ness KP et al. Identification of amino acid residues essential for high aflatoxin B1-8,9-epoxide conjugation activity in alpha class glutathione S-transferases through site-directed mutagenesis. 1998 Toxicol. Appl. Pharmacol. pmid:9772212
Kaplanski C et al. Rearrangements in minisatellite sequences induced by aflatoxin B1 in a metabolically competent strain of Saccharomyces cerevisiae. 1998 Carcinogenesis pmid:9771940
Maxuitenko YY et al. Identification of dithiolethiones with better chemopreventive properties than oltipraz. 1998 Carcinogenesis pmid:9771932
Suttajit M Current status of aflatoxin and its control in Thailand. 1998 J Toxicol Sci pmid:9760457
Makarananda K et al. Monitoring of aflatoxin exposure by biomarkers. 1998 J Toxicol Sci pmid:9760454
Ueng YF et al. Aflatoxin B1 oxidation by human cytochrome P450s. 1998 J Toxicol Sci pmid:9760449
Meyers DM et al. Characterization of aflJ, a gene required for conversion of pathway intermediates to aflatoxin. 1998 Appl. Environ. Microbiol. pmid:9758789
Gyamfi MA and Aniya Y Medicinal herb, Thonningia sanguinea protects against aflatoxin B1 acute hepatotoxicity in Fischer 344 rats. 1998 Hum Exp Toxicol pmid:9756133
Harris AJ et al. Identification of differentially expressed genes in aflatoxin B1-treated cultured primary rat hepatocytes and Fischer 344 rats. 1998 Carcinogenesis pmid:9744542
Cavin C et al. The coffee-specific diterpenes cafestol and kahweol protect against aflatoxin B1-induced genotoxicity through a dual mechanism. 1998 Carcinogenesis pmid:9744531
Yamada A et al. In vivo detection of mutations induced by aflatoxin B1 using human CYP3A7/HITEC hybrid mice. 1998 Biochem. Biophys. Res. Commun. pmid:9735348
Beamand JA et al. Lack of effect of coumarin on unscheduled DNA synthesis in precision-cut human liver slices. 1998 Food Chem. Toxicol. pmid:9734715
Wang H et al. Structure-function relationships of human liver cytochromes P450 3A: aflatoxin B1 metabolism as a probe. 1998 Biochemistry pmid:9730826
Dalcero A et al. Mycoflora and naturally occurring mycotoxins in poultry feeds in Argentina. 1998 Mycopathologia pmid:9725029
Ghaly MF et al. Use of propolis and ultragriseofulvin to inhibit aflatoxigenic fungi. 1998 Folia Microbiol. (Praha) pmid:9721607
Miyazawa M et al. Suppression of the SOS-inducing activity of Trp-P-1 and aflatoxin B1 by meso-dihydroguaiaretic acid from Machilus thunbergii in the Salmonella typhimurium TA1535/pSK1002 umu test. 1998 Biosci. Biotechnol. Biochem. pmid:9720227
Goeger DE et al. Coumarin chemoprotection against aflatoxin B1-induced gene mutation in a mammalian cell system: a species difference in mutagen activation and protection with chick embryo and rat liver S9. 1998 Environ. Mol. Mutagen. pmid:9707100
Neal GE et al. Metabolism and toxicity of aflatoxins M1 and B1 in human-derived in vitro systems. 1998 Toxicol. Appl. Pharmacol. pmid:9705898
Jones WR et al. Refined structure of the doubly intercalated d(TATAFBGCATA)2 aflatoxin B1 adduct. 1998 Chem. Res. Toxicol. pmid:9705748
Liu DL et al. Detoxification of aflatoxin B1 by enzymes isolated from Armillariella tabescens. 1998 Food Chem. Toxicol. pmid:9687963
Iida N et al. Suppression of arachidonic acid cascade-mediated apoptosis in aflatoxin B1-induced rat hepatoma cells by glucocorticoids. 1998 Carcinogenesis pmid:9683177
Ibeh IN and Saxena DK Effect of alpha-tocopherol supplementation on the impact of aflatoxin B1 on the testes of rats. 1998 Exp. Toxicol. Pathol. pmid:9681652
Hayes JD et al. Regulation of rat glutathione S-transferase A5 by cancer chemopreventive agents: mechanisms of inducible resistance to aflatoxin B1. 1998 Chem. Biol. Interact. pmid:9679543
Guengerich FP et al. Activation and detoxication of aflatoxin B1. 1998 Mutat. Res. pmid:9675258
Kusamran WR et al. Effects of neem flowers, Thai and Chinese bitter gourd fruits and sweet basil leaves on hepatic monooxygenases and glutathione S-transferase activities, and in vitro metabolic activation of chemical carcinogens in rats. 1998 Food Chem. Toxicol. pmid:9674955
Beamand JA et al. Effect of some cooked food mutagens on unscheduled DNA synthesis in cultured precision-cut rat, mouse and human liver slices. 1998 Food Chem. Toxicol. pmid:9674953
Gopalaswamy UV et al. Chemopreventive effects of dithiocarbamates on aflatoxin B1 metabolism and formation of AFB1 adducts with glutathione. 1998 May-Jun Anticancer Res. pmid:9673411