CYTOCHALASIN B

CYTOCHALASIN B is a lipid of Polyketides (PK) class. Cytochalasin b is associated with abnormalities such as Renal tubular disorder and Chagas Disease. The involved functions are known as Membrane Protein Traffic, inhibitors, Metabolic Inhibition, Biochemical Pathway and Increased Sensitivy. Cytochalasin b often locates in Cytoplasmic matrix, Plasma membrane, Microtubules, Extracellular and Protoplasm. The associated genes with CYTOCHALASIN B are SLC2A2 gene, PFDN5 gene, SLC2A1 gene, OMG gene and SPEN gene. The related lipids are Steroids, Lipopolysaccharides and Liposomes. The related experimental models are Xenograft Model.

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Introduction

To understand associated biological information of CYTOCHALASIN B, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with CYTOCHALASIN B?

CYTOCHALASIN B is suspected in Renal tubular disorder, Chagas Disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with CYTOCHALASIN B

MeSH term MeSH ID Detail
Body Weight D001835 333 associated lipids
Lung Neoplasms D008175 171 associated lipids
Adenocarcinoma D000230 166 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Hemolysis D006461 131 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Inflammation D007249 119 associated lipids
Hypertension D006973 115 associated lipids
Glioma D005910 112 associated lipids
Insulin Resistance D007333 99 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Arteriosclerosis D001161 86 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Alzheimer Disease D000544 76 associated lipids
Leukemia D007938 74 associated lipids
Melanoma D008545 69 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Dermatitis, Contact D003877 59 associated lipids
Leukemia, Myeloid D007951 52 associated lipids
Asthma D001249 52 associated lipids
Starvation D013217 47 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Leukemia, Experimental D007942 42 associated lipids
Leukemia, Erythroblastic, Acute D004915 41 associated lipids
Diabetic Nephropathies D003928 39 associated lipids
Thyroid Neoplasms D013964 33 associated lipids
Uremia D014511 33 associated lipids
Micronuclei, Chromosome-Defective D048629 33 associated lipids
Endometrial Neoplasms D016889 30 associated lipids
Kidney Diseases D007674 29 associated lipids
Insulinoma D007340 28 associated lipids
Hyperinsulinism D006946 27 associated lipids
Cell Transformation, Viral D002472 26 associated lipids
Lymphoma, B-Cell D016393 24 associated lipids
Birth Weight D001724 23 associated lipids
Medulloblastoma D008527 22 associated lipids
Malaria, Falciparum D016778 22 associated lipids
Carcinoma 256, Walker D002279 22 associated lipids
Hypoxia-Ischemia, Brain D020925 22 associated lipids
Anemia D000740 21 associated lipids
Wounds and Injuries D014947 20 associated lipids
Tuberculosis D014376 20 associated lipids
Leukemia, Lymphoid D007945 18 associated lipids
Lymphoma D008223 18 associated lipids
Leukemia, Myelogenous, Chronic, BCR-ABL Positive D015464 17 associated lipids
Thrombocytopenia D013921 15 associated lipids
Burkitt Lymphoma D002051 15 associated lipids
Thymus Neoplasms D013953 15 associated lipids
Neutropenia D009503 15 associated lipids
Tongue Neoplasms D014062 15 associated lipids
Hypoglycemia D007003 13 associated lipids
Glucose Intolerance D018149 13 associated lipids
Eye Diseases D005128 12 associated lipids
Lymphoma, T-Cell D016399 11 associated lipids
Congenital Abnormalities D000013 11 associated lipids
Foreign-Body Reaction D005549 10 associated lipids
Carbon Monoxide Poisoning D002249 9 associated lipids
Chondrosarcoma D002813 9 associated lipids
Aggressive Periodontitis D010520 8 associated lipids
Adenoma, Islet Cell D007516 7 associated lipids
Lymphoproliferative Disorders D008232 7 associated lipids
Trisomy D014314 6 associated lipids
Ataxia Telangiectasia D001260 6 associated lipids
Galactosemias D005693 5 associated lipids
Infectious Mononucleosis D007244 5 associated lipids
Granulomatosis with Polyangiitis D014890 5 associated lipids
Chancroid D002602 4 associated lipids
Granulomatous Disease, Chronic D006105 4 associated lipids
Systemic Inflammatory Response Syndrome D018746 4 associated lipids
Pharyngeal Neoplasms D010610 4 associated lipids
Pituitary Neoplasms D010911 4 associated lipids
Coronavirus Infections D018352 4 associated lipids
Wiskott-Aldrich Syndrome D014923 3 associated lipids
CREST Syndrome D017675 2 associated lipids
Factor XII Deficiency D005175 2 associated lipids
Erythroblastosis, Fetal D004899 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with CYTOCHALASIN B

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with CYTOCHALASIN B?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with CYTOCHALASIN B?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with CYTOCHALASIN B?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with CYTOCHALASIN B?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with CYTOCHALASIN B?

Xenograft Model

Xenograft Model are used in the study 'Endofacial competitive inhibition of the glucose transporter 1 activity by gossypol.' (Pérez A et al., 2009).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with CYTOCHALASIN B

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Authors Title Published Journal PubMed Link
Lambert DT and Crowe JH Colchicine, cytochalasin B, cyclic AMP, and pigment granule translocation in melanophores of Uca pugilator and Hemigrapsus oregonensis (Crustacea: Decapoda). 1976 Comp. Biochem. Physiol. C, Comp. Pharmacol. pmid:8255
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Batt ER et al. Impermeant maleimides. Identification of an exofacial component of the human erythrocyte hexose transport mechanism. 1976 J. Biol. Chem. pmid:993210
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Schroeder PC and Pendergrass P The inhibition of in-vitro ovulation from follicles of the teleost, Oryzias latipes, by cytochalasin B. 1976 J. Reprod. Fertil. pmid:994105
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Poste G and Nicolson GL Calcium ionophores A23187 and X537A affect cell agglutination by lectins and capping of lymphocyte surface immunoglobulins. 1976 Biochim. Biophys. Acta pmid:764879
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Gordon S and Werb Z Secretion of macrophage neutral proteinase is enhanced by colchicine. 1976 Proc. Natl. Acad. Sci. U.S.A. pmid:176659
Byers B and Goetsch L A highly ordered ring of membrane-associated filaments in budding yeast. 1976 J. Cell Biol. pmid:773946
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Greene WC et al. Cytochalasin sensitive structures and lymphocyte activation. 1976 Exp. Cell Res. pmid:186286
Farber FE and Eberle R Effects of cytochalasin and alkaloid drugs on the biological expression of herpes simplex virus type 2 DNA. 1976 Exp. Cell Res. pmid:186287
Tou JS and Maier C Phospholipid metabolism and lysosomal enzyme secretion by leukocytes. Effects of dibutyryl cyclic adenosine 3':5'-monophosphate and ATP. 1976 Biochim. Biophys. Acta pmid:187223
Furcht LT et al. Independent alterations in cell shape and intramembranous particle topography induced by cytochalasin B and colchicine in normal and transformed cells. 1976 Cancer Res. pmid:187328
Lonchampt MO et al. Microtubules and microfilaments of bovine lens epithelial cells: electron microscopy and immunofluorescence staining with specific antibodies. 1976 Exp. Eye Res. pmid:187441
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Bissell MJ Transport as a rate limiting step in glucose metabolism in virus-transformed cells: studies with cytochalasin B. 1976 J. Cell. Physiol. pmid:188839
Atlas SJ and Lin S High-affinity cytochalasin B binding to normal and transformed BALB/3T3 cells. 1976 J. Cell. Physiol. pmid:188845
Banerjee SN et al. Requirement of cell nucleus for the replication of an arenavirus. 1975-1976 Intervirology pmid:1235853
Hoffstein S and Weissmann G Mechanisms of lysosomal enzyme release from leukocytes. IV. Interaction of monosodium urate crystals with dogfish and human leukocytes. 1975 Mar-Apr Arthritis Rheum. pmid:48382
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Bernard DP et al. Regulation of lymphocyte responses in vitro. VI. -Potentiation of the response to phytohemagglutinin by cytochalasin B. 1975 Feb-Mar Ann. Immunol. (Paris) pmid:1190745
Bernard DP and Waksman BH Regulation of lymphocyte responses in vitro. VII. - "Cell contact inhibition", a possible regulatory mechanism for lymphocyte activation. 1975 Feb-Mar Ann. Immunol. (Paris) pmid:1190746
Malaisse WJ et al. The stimulus-secretion coupling of glucose-induced insulin release XIX. The insulinotropic effect of glyceraldehyde. 1975 Dec-1976 Jan Mol. Cell. Endocrinol. pmid:1107091
Ruch JV et al. [Effects of cytochalasin B and colchicine on dental cytodifferentiation in vitro]. 1975 Apr-Jun Arch Anat Microsc Morphol Exp pmid:1217902
Hsu LS and Becker EL Volume changes induced in rabbit polymorphonuclear leukocytes by chemotactic factor and cytochalasin B. 1975 Am. J. Pathol. pmid:1180327