CYTOCHALASIN B is a lipid of Polyketides (PK) class. Cytochalasin b is associated with abnormalities such as Renal tubular disorder and Chagas Disease. The involved functions are known as Membrane Protein Traffic, inhibitors, Metabolic Inhibition, Biochemical Pathway and Increased Sensitivy. Cytochalasin b often locates in Cytoplasmic matrix, Plasma membrane, Microtubules, Extracellular and Protoplasm. The associated genes with CYTOCHALASIN B are SLC2A2 gene, PFDN5 gene, SLC2A1 gene, OMG gene and SPEN gene. The related lipids are Steroids, Lipopolysaccharides and Liposomes. The related experimental models are Xenograft Model.
To understand associated biological information of CYTOCHALASIN B, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
CYTOCHALASIN B is suspected in Renal tubular disorder, Chagas Disease and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with CYTOCHALASIN B
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Xenograft Model are used in the study 'Endofacial competitive inhibition of the glucose transporter 1 activity by gossypol.' (Pérez A et al., 2009).
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Authors | Title | Published | Journal | PubMed Link |
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Mrotek JJ and Hall PF | Response of adrenal tumor cells to adrenocorticotropin: site of inhibition by cytochalasin B. | 1977 | Biochemistry | pmid:196628 |
Baldwin SA et al. | Monosaccharide transporter of the human erythrocyte. Characterization of an improved preparation. | 1982 | Biochemistry | pmid:6890381 |
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Tai PK and Carter-Su C | Monoclonal antibody to the human glucose transporter that differentiates between the glucose and nucleoside transporters. | 1988 | Biochemistry | pmid:3191107 |
Bloch R | Inhibition of glucose transport in the human erythrocyte by cytochalasin B. | 1973 | Biochemistry | pmid:4773858 |
Carruthers A and Helgerson AL | Inhibitions of sugar transport produced by ligands binding at opposite sides of the membrane. Evidence for simultaneous occupation of the carrier by maltose and cytochalasin B. | 1991 | Biochemistry | pmid:2018762 |
Blodgett DM and Carruthers A | Quench-flow analysis reveals multiple phases of GluT1-mediated sugar transport. | 2005 | Biochemistry | pmid:15709778 |
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Freer RJ et al. | Further studies on the structural requirements for synthetic peptide chemoattractants. | 1980 | Biochemistry | pmid:7387981 |
Lachaal M et al. | Cadmium increases GLUT1 substrate binding affinity in vitro while reducing its cytochalasin B binding affinity. | 1996 | Biochemistry | pmid:8942661 |
Himmelreich U et al. | 13C NMR studies of vitamin C transport and its redox cycling in human erythrocytes. | 1998 | Biochemistry | pmid:9585573 |
Robichaud T et al. | Determinants of ligand binding affinity and cooperativity at the GLUT1 endofacial site. | 2011 | Biochemistry | pmid:21384913 |
Brekkan E et al. | Immobilized membrane vesicle or proteoliposome affinity chromatography. Frontal analysis of interactions of cytochalasin B and D-glucose with the human red cell glucose transporter. | 1996 | Biochemistry | pmid:8810921 |
May JM et al. | Localization of a reactive exofacial sulfhydryl on the glucose carrier of human erythrocytes. | 1990 | Biochemistry | pmid:2261480 |
Sampath P and Pollard TD | Effects of cytochalasin, phalloidin, and pH on the elongation of actin filaments. | 1991 | Biochemistry | pmid:1899622 |
Sogin DC and Hinkle PC | Binding of cytochalasin B to human erythrocyte glucose transporter. | 1980 | Biochemistry | pmid:7192569 |
Carruthers A | Anomalous asymmetric kinetics of human red cell hexose transfer: role of cytosolic adenosine 5'-triphosphate. | 1986 | Biochemistry | pmid:3718945 |
Katzen HM et al. | Evidence that the insulin-like activities of concanavalin A and insulin are mediated by a common insulin receptor linked effector system. | 1981 | Biochemistry | pmid:7028110 |
Anichini E et al. | Interaction of urokinase-type plasminogen activator with its receptor rapidly induces activation of glucose transporters. | 1997 | Biochemistry | pmid:9115983 |
Yang Q and Lundahl P | Immobilized proteoliposome affinity chromatography for quantitative analysis of specific interactions between solutes and membrane proteins. Interaction of cytochalasin B and D-glucose with the glucose transporter Glut1. | 1995 | Biochemistry | pmid:7779771 |
Scarlata S et al. | Effect of lipid packing on the conformational states of purified GLUT-1 hexose transporter. | 1995 | Biochemistry | pmid:7779817 |
Hamill S et al. | The human erythrocyte sugar transporter presents two sugar import sites. | 1999 | Biochemistry | pmid:10606533 |
Gorga FR and Lienhard GE | Changes in the intrinsic fluorescence of the human erythrocyte monosaccharide transporter upon ligand binding. | 1982 | Biochemistry | pmid:7200802 |
Baldwin SA et al. | Purification of the cytochalasin B binding component of the human erythrocyte monosaccharide transport system. | 1979 | Biochim. Biophys. Acta | pmid:435493 |
Riordan JR and Alon N | Binding of [3H]ctyochalasin B and [3H]colchicine to isolated liver plasma membranes. | 1977 | Biochim. Biophys. Acta | pmid:13829 |
Clark CM and Goodlad GA | Plasma membrane associated actin in liver of normal and tumour-bearing rats. | 1985 | Biochim. Biophys. Acta | pmid:4052415 |
Hallett MB | Quantal secretion and response lag demonstrated in single rat neutrophils. | 1985 | Biochim. Biophys. Acta | pmid:4052458 |
Englund AK and Lundahl P | The isoelectric point of the human red cell glucose transporter. | 1991 | Biochim. Biophys. Acta | pmid:2059652 |
Maruyama K et al. | Cytochalasin B and the structure of actin gels. II. Further evidence for the splitting of F-actin by cytochalasin B. | 1980 | Biochim. Biophys. Acta | pmid:6894243 |
Parisi M et al. | The role of microtubules and microfilaments in the hydrosmotic response to antidiuretic hormone. | 1985 | Biochim. Biophys. Acta | pmid:2410025 |
Wessling M and Pilch PF | Characterization and solubilization of the cytochalasin B binding component from human placental microsomes. | 1984 | Biochim. Biophys. Acta | pmid:6541505 |
Mendz GL et al. | Characterisation of glucose transport in Helicobacter pylori. | 1995 | Biochim. Biophys. Acta | pmid:7599143 |
Higashi N et al. | Fusion between Jurkat cell and PEO-lipid modified liposome. | 1996 | Biochim. Biophys. Acta | pmid:8972702 |
Hashimoto K et al. | Activation of phospholipases in platelets by polyclonal antibodies against a surface membrane protein. | 1992 | Biochim. Biophys. Acta | pmid:1420344 |
Hall PF et al. | The actions of various cytochalasins on mouse adrenal tumor cells in relation to trophic stimulation of steroidogenesis. | 1981 | Biochim. Biophys. Acta | pmid:6269652 |
Lindgren CA et al. | Isolated cardiac myocytes. A new cellular model for studying insulin modulation of monosaccharide transport. | 1982 | Biochim. Biophys. Acta | pmid:6760900 |
Ingermann RL et al. | D-Glucose-sensitive and -insensitive cytochalasin B binding proteins from microvillous plasma membranes of human placenta. Identification of the D-glucose transporter. | 1983 | Biochim. Biophys. Acta | pmid:6681985 |
Mietto L et al. | Internalization of phosphatidylserine by adherent and non-adherent rat mononuclear cells. | 1989 | Biochim. Biophys. Acta | pmid:2790035 |
Zala CA and Perdue JF | Stereospecific D-glucose transport in mixed membrane and plasma membrane vesicles derived from cultured chick embryo fibroblasts. | 1980 | Biochim. Biophys. Acta | pmid:6249359 |
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Borge L et al. | Type II transglutaminase expression in rabbit articular chondrocytes in culture: relation with cell differentiation, cell growth, cell adhesion and cell apoptosis. | 1996 | Biochim. Biophys. Acta | pmid:8672533 |
Ishii T et al. | Facilitated glucose transporter of human erythrocyte: proteolytic mapping of the [3H]cytochalasin B photoaffinity-labeled transporter polypeptide. | 1985 | Biochim. Biophys. Acta | pmid:3902090 |
Jones MN and Nickson JK | Monosaccharide transport proteins of the human erythrocyte membrane. | 1981 | Biochim. Biophys. Acta | pmid:7196262 |
Melchior DL et al. | Alterations in red blood cell sugar transport by nanomolar concentrations of alkyl lysophospholipid. | 1990 | Biochim. Biophys. Acta | pmid:2207116 |