CYTOCHALASIN B is a lipid of Polyketides (PK) class. Cytochalasin b is associated with abnormalities such as Renal tubular disorder and Chagas Disease. The involved functions are known as Membrane Protein Traffic, inhibitors, Metabolic Inhibition, Biochemical Pathway and Increased Sensitivy. Cytochalasin b often locates in Cytoplasmic matrix, Plasma membrane, Microtubules, Extracellular and Protoplasm. The associated genes with CYTOCHALASIN B are SLC2A2 gene, PFDN5 gene, SLC2A1 gene, OMG gene and SPEN gene. The related lipids are Steroids, Lipopolysaccharides and Liposomes. The related experimental models are Xenograft Model.
To understand associated biological information of CYTOCHALASIN B, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
CYTOCHALASIN B is suspected in Renal tubular disorder, Chagas Disease and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with CYTOCHALASIN B
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Xenograft Model are used in the study 'Endofacial competitive inhibition of the glucose transporter 1 activity by gossypol.' (Pérez A et al., 2009).
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Authors | Title | Published | Journal | PubMed Link |
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Ni Z et al. | [Primary study on the sensitivity of cytokinesis blocked micronucleus assay in CHL cells]. | 1997 | Hua Xi Yi Ke Da Xue Xue Bao | pmid:10684043 |
Romani AM et al. | Parallel stimulation of glucose and Mg(2+) accumulation by insulin in rat hearts and cardiac ventricular myocytes. | 2000 | Circ. Res. | pmid:10679485 |
Rengan R et al. | Actin cytoskeletal function is spared, but apoptosis is increased, in WAS patient hematopoietic cells. | 2000 | Blood | pmid:10666201 |
Pinkofsky HB et al. | The inhibition of GLUT1 glucose transport and cytochalasin B binding activity by tricyclic antidepressants. | 2000 | Life Sci. | pmid:10666003 |
Ferhat L et al. | The nuclear/mitotic apparatus protein NuMA is a component of the somatodendritic microtubule arrays of the neuron. | 1998 | J. Neurocytol. | pmid:10659681 |
Christopher CW et al. | Paradoxical effects of cycloheximide and cytochalasin B on hamster cell hexose uptake. | 1976 | Proc. Natl. Acad. Sci. U.S.A. | pmid:1065898 |
Schlessinger J et al. | Lateral transport on cell membranes: mobility of concanavalin A receptors on myoblasts. | 1976 | Proc. Natl. Acad. Sci. U.S.A. | pmid:1065895 |
Koukouritaki SB et al. | Tyrosine phosphorylation of focal adhesion kinase and paxillin regulates the signaling mechanism of the rapid nongenomic action of dexamethasone on actin cytoskeleton. | 1999 | Mol. Med. | pmid:10656875 |
Scherberich A et al. | Migration of human vascular smooth muscle cells involves serum-dependent repeated cytosolic calcium transients. | 2000 | J. Cell. Sci. | pmid:10652258 |
Matsuoka A et al. | The 2-phenylbenzotriazole-type water pollutant PBTA-2 has cytochalasin B-mimetic activity. | 2000 | Mutat. Res. | pmid:10648903 |