CYTOCHALASIN B is a lipid of Polyketides (PK) class. Cytochalasin b is associated with abnormalities such as Renal tubular disorder and Chagas Disease. The involved functions are known as Membrane Protein Traffic, inhibitors, Metabolic Inhibition, Biochemical Pathway and Increased Sensitivy. Cytochalasin b often locates in Cytoplasmic matrix, Plasma membrane, Microtubules, Extracellular and Protoplasm. The associated genes with CYTOCHALASIN B are SLC2A2 gene, PFDN5 gene, SLC2A1 gene, OMG gene and SPEN gene. The related lipids are Steroids, Lipopolysaccharides and Liposomes. The related experimental models are Xenograft Model.
To understand associated biological information of CYTOCHALASIN B, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
CYTOCHALASIN B is suspected in Renal tubular disorder, Chagas Disease and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with CYTOCHALASIN B
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Xenograft Model are used in the study 'Endofacial competitive inhibition of the glucose transporter 1 activity by gossypol.' (Pérez A et al., 2009).
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Kazhdan M et al. | Human neutrophil respiratory burst response to influenza A virus occurs at an intracellular location. | 1994 | J. Leukoc. Biol. | pmid:8027671 |
GarcÃa-GarcÃa E et al. | Phosphatidylinositol 3-kinase and ERK are required for NF-kappaB activation but not for phagocytosis. | 2001 | J. Leukoc. Biol. | pmid:11590203 |
Bates EJ et al. | Docosahexanoic acid (22:6, n-3) but not eicosapentaenoic acid (20:5, n-3) can induce neutrophil-mediated injury of cultured endothelial cells: involvement of neutrophil elastase. | 1993 | J. Leukoc. Biol. | pmid:8245712 |
Van Epps DE et al. | Modulation of neutrophil-reduced pyridine nucleotide content following stimulation with phorbol myristate acetate and chemotactic factors. | 1985 | J. Leukoc. Biol. | pmid:2995525 |
Mukherjee G et al. | Remodeling of the plasma membrane after stimulation of neutrophils with f-Met-Leu-Phe and dihydrocytochalasin B: identification of membrane subdomains containing NADPH oxidase activity. | 1994 | J. Leukoc. Biol. | pmid:8195693 |
Seetoo KF et al. | A cytosolic calcium transient is not necessary for degranulation or oxidative burst in immune complex-stimulated neutrophils. | 1997 | J. Leukoc. Biol. | pmid:9307071 |
Miron S et al. | Pervanadate-induced adhesion of CD4+ T cell to fibronectin is associated with tyrosine phosphorylation of paxillin. | 1997 | J. Leukoc. Biol. | pmid:9307082 |
Gjøen T et al. | Binding of metastatic colon carcinoma cells to liver macrophages. | 1989 | J. Leukoc. Biol. | pmid:2495336 |
Sha'afi RI et al. | Dissociation of the 47-kilodalton protein phosphorylation from degranulation and superoxide production in neutrophils. | 1988 | J. Leukoc. Biol. | pmid:2826626 |
Kito K et al. | MCP-1 receptor binding affinity is up-regulated by pre-stimulation with MCP-1 in an actin polymerization-dependent manner. | 2001 | J. Leukoc. Biol. | pmid:11310855 |
Bengtsson T et al. | Actin assembly and regulation of neutrophil function: effects of cytochalasin B and tetracaine on chemotactic peptide-induced O2- production and degranulation. | 1991 | J. Leukoc. Biol. | pmid:1847714 |
Manara FS et al. | Role of degranulation in activation of the respiratory burst in human neutrophils. | 1991 | J. Leukoc. Biol. | pmid:1849954 |
Kusunoki T et al. | Involvement of CD11b/CD18 in enhanced neutrophil adhesion by Fc gamma receptor stimulation. | 1994 | J. Leukoc. Biol. | pmid:7910840 |
Dib K et al. | The histamine H4 receptor is a potent inhibitor of adhesion-dependent degranulation in human neutrophils. | 2014 | J. Leukoc. Biol. | pmid:24799603 |
Smith RJ et al. | Diacylglycerols modulate human polymorphonuclear neutrophil responsiveness: effects on intracellular calcium mobilization, granule exocytosis, and superoxide anion production. | 1988 | J. Leukoc. Biol. | pmid:2836539 |
Földes-Filep E and Filep JG | Mepacrine inhibits fMLP-induced activation of human neutrophil granulocytes, leukotriene B4 formation, and fMLP binding. | 1992 | J. Leukoc. Biol. | pmid:1331280 |
Richter J | Effect of adenosine analogues and cAMP-raising agents on TNF-, GM-CSF-, and chemotactic peptide-induced degranulation in single adherent neutrophils. | 1992 | J. Leukoc. Biol. | pmid:1371803 |
Woods GM et al. | Processing of complex antigens and simple hapten-like molecules by epidermal Langerhans cells. | 1995 | J. Leukoc. Biol. | pmid:7790772 |
Tissot M et al. | Polyphosphoinositide metabolism in polymorphonuclear cells from healthy and thermally injured rats: effect of the immunomodulator RU 41740. | 1991 | J. Leukoc. Biol. | pmid:1658175 |
Fittschen C and Henson PM | Selective secretion of azurophil granule contents induced by monovalent cation ionophores in human neutrophils: evidence for direct ionophore effects on the granule membrane. | 1991 | J. Leukoc. Biol. | pmid:1660915 |
Nauclér C et al. | Signaling to localized degranulation in neutrophils adherent to immune complexes. | 2002 | J. Leukoc. Biol. | pmid:11927658 |
Lichtman SN et al. | Lipopolysaccharide-stimulated TNF-alpha release from cultured rat Kupffer cells: sequence of intracellular signaling pathways. | 1998 | J. Leukoc. Biol. | pmid:9738664 |
Smallwood JI and Malawista SE | Protein kinase C isoforms in human neutrophil cytoplasts. | 1992 | J. Leukoc. Biol. | pmid:1311015 |
Ozaki Y et al. | Potentiation of neutrophil function by recombinant DNA-produced interleukin 1a. | 1987 | J. Leukoc. Biol. | pmid:3500253 |
Rahat MA et al. | Hypoxia reduces the output of matrix metalloproteinase-9 (MMP-9) in monocytes by inhibiting its secretion and elevating membranal association. | 2006 | J. Leukoc. Biol. | pmid:16434697 |
Cypcar D et al. | Rat eosinophils: isolation and characterization of superoxide production. | 1996 | J. Leukoc. Biol. | pmid:8699113 |
Bohnsack JF et al. | Mechanisms of beta 1 integrin-dependent adherence of granulocytic HL60 to fibronectin. | 1995 | J. Leukoc. Biol. | pmid:7536788 |
Chadwick VS et al. | Assessment of neutrophil leukocyte secretory response to fMLP in whole blood in vitro. | 1992 | J. Leukoc. Biol. | pmid:1506768 |
Masuda M et al. | Change of membrane fluidity of rat neutrophils accompanying Escherichia coli inoculation. | 1989 | J. Leukoc. Biol. | pmid:2501441 |
Huang CK and Laramee GR | Stimulation of a histone H4 protein kinase in Triton X-100 lysates of rabbit peritoneal neutrophils pretreated with chemotactic factors: effect of leukotriene B4 and cytochalasin B. | 1991 | J. Leukoc. Biol. | pmid:1846903 |
Broussas M et al. | Inhibition of fMLP-triggered respiratory burst of human monocytes by adenosine: involvement of A3 adenosine receptor. | 1999 | J. Leukoc. Biol. | pmid:10496321 |
Wenzel-Seifert K et al. | Complex regulation of human neutrophil activation by actin filaments: dihydrocytochalasin B and botulinum C2 toxin uncover the existence of multiple cation entry pathways. | 1997 | J. Leukoc. Biol. | pmid:9201261 |
Fletcher MP and Seligmann BE | Monitoring human neutrophil granule secretion by flow cytometry: secretion and membrane potential changes assessed by light scatter and a fluorescent probe of membrane potential. | 1985 | J. Leukoc. Biol. | pmid:3855949 |
Labadia ME et al. | A synthetic peptide containing a predominant protein kinase C site within p47phox inhibits the NADPH oxidase in intact neutrophils. | 1996 | J. Leukoc. Biol. | pmid:8558059 |
Wiles ME et al. | Regulation of polymorphonuclear leukocyte membrane fluidity: effect of cytoskeletal modification. | 1994 | J. Leukoc. Biol. | pmid:7915297 |
Egesten A et al. | Phorbol ester-induced degranulation in adherent human eosinophil granulocytes is dependent on CD11/CD18 leukocyte integrins. | 1993 | J. Leukoc. Biol. | pmid:8095965 |
Arvieux J et al. | Neutrophil activation by anti-beta 2 glycoprotein I monoclonal antibodies via Fc gamma receptor II. | 1995 | J. Leukoc. Biol. | pmid:7884309 |
Karabasil MR et al. | Trafficking of GFP-AQP5 chimeric proteins conferred with unphosphorylated amino acids at their PKA-target motif ((152)SRRTS) in MDCK-II cells. | 2009 | J. Med. Invest. | pmid:19262015 |
Brown T | Inhibition by amoeba-specific antiserum and by cytochalasin B of the cytopathogenicity of Naegleria fowleri in mouse embryo-cell cultures. | 1979 | J. Med. Microbiol. | pmid:469930 |
Taylor G and Howard CJ | Interaction of Mycoplasma pulmonis with mouse peritoneal macrophages and polymorphonuclear leucocytes. | 1980 | J. Med. Microbiol. | pmid:7359575 |
Thornley JP et al. | Adherence of Aeromonas caviae to human cell lines Hep-2 and Caco-2. | 1996 | J. Med. Microbiol. | pmid:8958248 |
Barrow PA and Lovell MA | Invasion of Vero cells by Salmonella species. | 1989 | J. Med. Microbiol. | pmid:2643706 |
Andrade JR et al. | An endocytic process in HEp-2 cells induced by enteropathogenic Escherichia coli. | 1989 | J. Med. Microbiol. | pmid:2643705 |
Jung KY et al. | Involvement of staphylococcal protein A and cytoskeletal actin in Staphylococcus aureus invasion of cultured human oral epithelial cells. | 2001 | J. Med. Microbiol. | pmid:11192502 |
Richardson MD and Chung I | GM-CSF-modulated phagocytosis of Trichosporon beigelii by human neutrophils. | 1997 | J. Med. Microbiol. | pmid:9128196 |
Chu JJ et al. | Actin filaments participate in West Nile (Sarafend) virus maturation process. | 2003 | J. Med. Virol. | pmid:12966555 |
Lucas WJ and Dainty J | Spatial distribution of functional OH- carriers along a characean internodal cell: determined by the effect of cytochalasin B on H14CO3- assimilation. | 1977 | J. Membr. Biol. | pmid:16139 |
Janoshazi A and Solomon AK | Interaction among anion, cation and glucose transport proteins in the human red cell. | 1989 | J. Membr. Biol. | pmid:2593137 |
Gershon ND et al. | Computer assisted analysis of ferritin-insulin receptor sites on adipocytes and the effects of cytochalasin B on groups of insulin receptor sites. | 1981 | J. Membr. Biol. | pmid:7218336 |
Plagemann PG et al. | Membrane effects of cytochalasin B. Competitive inhibition of facilitated diffusion processes in rat hepatoma cells and other cell lines and effect on formation of functional transport sites. | 1975 | J. Membr. Biol. | pmid:1165581 |
Hakimian J and Ismail-Beigi F | Enhancement of glucose transport in clone 9 cells by exposure to alkaline pH: studies on potential mechanisms. | 1991 | J. Membr. Biol. | pmid:1708427 |
Cornet M et al. | Relation between cytoskeleton, hypo-osmotic treatment and volume regulation in Ehrlich ascites tumor cells. | 1993 | J. Membr. Biol. | pmid:8433352 |
Pasternak CA and Micklem KJ | Permeability changes during cell fusion. | 1973 | J. Membr. Biol. | pmid:4360299 |
Sánchez Olea R et al. | Osmolarity-sensitive release of free amino acids from cultured kidney cells (MDCK). | 1991 | J. Membr. Biol. | pmid:1646888 |
Niles WD and Malik AB | Endocytosis and exocytosis events regulate vesicle traffic in endothelial cells. | 1999 | J. Membr. Biol. | pmid:9878078 |
Maenz DD and Cheeseman CI | The Na+-independent D-glucose transporter in the enterocyte basolateral membrane: orientation and cytochalasin B binding characteristics. | 1987 | J. Membr. Biol. | pmid:3625759 |
Ito S et al. | Studies on the formation of a permeable cell membrane junction. I. Coupling under various conditions of membrane contact. Effects of colchicine, cytochalasin B, dinitrophenol. | 1974 | J. Membr. Biol. | pmid:4459472 |
Cornet M et al. | Cytoskeleton and ion movements during volume regulation in cultured PC12 cells. | 1993 | J. Membr. Biol. | pmid:7685822 |
Wolosin JM | Regeneration of resistance and ion transport in rabbit corneal epithelium after induced surface cell exfoliation. | 1988 | J. Membr. Biol. | pmid:3184177 |
Michalke W | A gradient of diffusible substance in a monolayer of cultured cells. | 1977 | J. Membr. Biol. | pmid:864683 |
Jansson T and Illsley NP | Osmotic water permeabilities of human placental microvillous and basal membranes. | 1993 | J. Membr. Biol. | pmid:8496946 |
Janoshazi A and Solomon AK | Initial steps of alpha- and beta-D-glucose binding to intact red cell membrane. | 1993 | J. Membr. Biol. | pmid:8496948 |
Liu X et al. | Stretch-activated potassium channels in hypotonically induced blebs of atrial myocytes. | 2008 Nov-Dec | J. Membr. Biol. | pmid:19015804 |
van Rossum GD and Russo MA | Ouabain-resistant mechanism of volume control and the ultrastructural organization of liver slices recovering from swelling in vitro. | 1981 | J. Membr. Biol. | pmid:7195430 |
Levitan I et al. | Modulation of a volume-regulated chloride current by F-actin. | 1995 | J. Membr. Biol. | pmid:8558594 |
Wang ZY et al. | Actin microfilament involved in regulation of pacemaking activity in cultured interstitial cells of Cajal from murine intestine. | 2010 | J. Membr. Biol. | pmid:20349180 |
Gonzalez-Mariscal L et al. | Tight junction formation in cultured epithelial cells (MDCK). | 1985 | J. Membr. Biol. | pmid:4032460 |
Hartwig JH and Stossel TP | Cytochalasin B and the structure of actin gels. | 1979 | J. Mol. Biol. | pmid:583431 |
Singh BN et al. | Association of alphaB-crystallin, a small heat shock protein, with actin: role in modulating actin filament dynamics in vivo. | 2007 | J. Mol. Biol. | pmid:17196975 |
Seraydarian MW et al. | Cytochalasin B: effect on mammalian cardiac muscle cells in culture. | 1973 | J. Mol. Cell. Cardiol. | pmid:4797448 |
Haneskog L et al. | Biomembrane affinity chromatographic analysis of nitrobenzylthioinosine binding to the reconstituted human red cell nucleoside transporter. | 1998 | J. Mol. Recognit. | pmid:10076807 |
Dabrowska R et al. | The effect of cytochalasin and glutaraldehyde on F-actin filaments containing muscle and non-muscle tropomyosin. | 1983 | J. Muscle Res. Cell. Motil. | pmid:6404932 |
Wright GL and Battistella-Patterson AS | Involvement of the cytoskeleton in calcium-dependent stress relaxation of rat aortic smooth muscle. | 1998 | J. Muscle Res. Cell. Motil. | pmid:9635283 |
Lin MC et al. | Eunicellin-based diterpenoids from the Formosan soft coral Klyxum molle with inhibitory activity on superoxide generation and elastase release by neutrophils. | 2013 | J. Nat. Prod. | pmid:24020806 |
Chen JJ et al. | Neolignans, a coumarinolignan, lignan derivatives, and a chromene: anti-inflammatory constituents from Zanthoxylum avicennae. | 2008 | J. Nat. Prod. | pmid:18211005 |
Muhammad I et al. | A new antimalarial quassinoid from Simaba orinocensis. | 2004 | J. Nat. Prod. | pmid:15165136 |
Muhammad I et al. | Antimalarial, cytotoxic, and antifungal alkaloids from Duguetia hadrantha. | 2001 | J. Nat. Prod. | pmid:11374943 |
Weng JR et al. | Anti-inflammatory constituents and new pterocarpanoid of Crotalaria pallida. | 2003 | J. Nat. Prod. | pmid:12662101 |
Chan HH et al. | Bioactive constituents from the roots of Panax japonicus var. major and development of a LC-MS/MS method for distinguishing between natural and artifactual compounds. | 2011 | J. Nat. Prod. | pmid:21417387 |
Musza LL et al. | Cucurbitacins, cell adhesion inhibitors from Conobea scoparioides. | 1994 | J. Nat. Prod. | pmid:7852999 |
Chen JJ et al. | Benzophenone derivatives from the fruits of Garcinia multiflora and their anti-inflammatory activity. | 2009 | J. Nat. Prod. | pmid:19203247 |
Muhammad I et al. | Antiparasitic alkaloids from Psychotria klugii. | 2003 | J. Nat. Prod. | pmid:12880315 |
Chou TH et al. | Phthalides from Pittosporum illicioides var. illicioides with inhibitory activity on superoxide generation and elastase release by neutrophils. | 2008 | J. Nat. Prod. | pmid:18817445 |
Johansson S et al. | A neutrophil multitarget functional bioassay to detect anti-inflammatory natural products. | 2002 | J. Nat. Prod. | pmid:11809061 |
Huang YC et al. | Anti-inflammatory flavonoids from the rhizomes of Helminthostachys zeylanica. | 2009 | J. Nat. Prod. | pmid:19583252 |
Kokoshka JM et al. | Cell-based screen for identification of inhibitors of tubulin polymerization. | 1996 | J. Nat. Prod. | pmid:8988604 |
Geder L et al. | Human cells transformed in vitro by human cytomegalovirus: tumorigenicity in athymic nude mice. | 1977 | J. Natl. Cancer Inst. | pmid:191621 |
Hart IR et al. | Effect of cytoskeleton-disrupting agents on the metastatic behavior of melanoma cells. | 1980 | J. Natl. Cancer Inst. | pmid:6929000 |
De Brabander M et al. | A new culture model facilitating rapid quantitative testing of mitotic spindle inhibition in mammalian cells. | 1976 | J. Natl. Cancer Inst. | pmid:1255766 |
Spiro TP and Mundy GR | In vitro migraton of Walker 256 carcinosarcoma cells: dependence on microtubule and microfilament function. | 1980 | J. Natl. Cancer Inst. | pmid:6931262 |
O'Neill FJ | Limitation of nuclear division by protease inhibitors in cytochalasin-B-treated tumor cells. | 1974 | J. Natl. Cancer Inst. | pmid:4857021 |
Borenfreund E et al. | Properties and malignant transformation of established rat liver parenchymal cells in culture. | 1975 | J. Natl. Cancer Inst. | pmid:1159824 |
O'Neill FJ | Brief communication: chromosome pulverization in cultured normal and neoplastic cells treated with cytochalasin B. | 1972 | J. Natl. Cancer Inst. | pmid:4675110 |
Cobb JP et al. | Response of Cloudman S91 melanoma cells to melanocytestimulating hormone: enhancement by cytochalasin B. | 1976 | J. Natl. Cancer Inst. | pmid:994199 |
Sethi KK and Brandis H | Protection of mice from malignant tumor implants by enucleated tumor cells. | 1974 | J. Natl. Cancer Inst. | pmid:4372368 |
Nunn ME et al. | Natural cytotoxic reactivity of rat lymphocytes against syngeneic Gross virus-induced lymphoma. | 1976 | J. Natl. Cancer Inst. | pmid:1082939 |
O'Neill FJ et al. | Differential response to cytochalasin B among cells transformed by DNA and RNA tumor viruses. | 1975 | J. Natl. Cancer Inst. | pmid:171432 |
O'Neill FJ | Limitation of multinucleation by dibutyryl adenosine 3',5'-cyclic monophosphate in tumor cells treated with cytochalasin B. | 1976 | J. Natl. Cancer Inst. | pmid:176385 |
O'Neill FJ | Suppression of uncontrolled nuclear division in somatic cell hybrids of normal and transformed cells. | 1980 | J. Natl. Cancer Inst. | pmid:6931930 |
Wu CF et al. | Giant Drosophila neurons differentiated from cytokinesis-arrested embryonic neuroblasts. | 1990 | J. Neurobiol. | pmid:2112589 |