CYTOCHALASIN B is a lipid of Polyketides (PK) class. Cytochalasin b is associated with abnormalities such as Renal tubular disorder and Chagas Disease. The involved functions are known as Membrane Protein Traffic, inhibitors, Metabolic Inhibition, Biochemical Pathway and Increased Sensitivy. Cytochalasin b often locates in Cytoplasmic matrix, Plasma membrane, Microtubules, Extracellular and Protoplasm. The associated genes with CYTOCHALASIN B are SLC2A2 gene, PFDN5 gene, SLC2A1 gene, OMG gene and SPEN gene. The related lipids are Steroids, Lipopolysaccharides and Liposomes. The related experimental models are Xenograft Model.
To understand associated biological information of CYTOCHALASIN B, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
CYTOCHALASIN B is suspected in Renal tubular disorder, Chagas Disease and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with CYTOCHALASIN B
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Xenograft Model are used in the study 'Endofacial competitive inhibition of the glucose transporter 1 activity by gossypol.' (Pérez A et al., 2009).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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O'Flaherty JT et al. | Neutrophil-degranulating action of 5,12-dihydroxy-6,8,10,14-eicosatetraenoic acid and 1-O-alkyl-2-O-acetyl-sn-glycero-3-phosphocholine. Comparison with other degranulating agents. | 1981 | Am. J. Pathol. | pmid:6274199 |
Aikawa M et al. | Interactions between macrophagelike cells and Leishmania braziliensis in vitro. | 1982 | Am. J. Pathol. | pmid:7091302 |
Elbim C et al. | Heterogeneity in Lewis-X and sialyl-Lewis-X antigen expression on monocytes in whole blood: relation to stimulus-induced oxidative burst. | 1998 | Am. J. Pathol. | pmid:9546369 |
Okayasu T et al. | Cytochalasin delays but does not prevent cell death from anoxia. | 1984 | Am. J. Pathol. | pmid:6541879 |
Becker EL et al. | Superoxide production induced in rabbit polymorphonuclear leukocytes by synthetic chemotactic peptides and A23187. | 1979 | Am. J. Pathol. | pmid:219701 |
O'Flaherty JT et al. | Neutrophil aggregation and degranulation. Effect of arachidonic acid. | 1979 | Am. J. Pathol. | pmid:453323 |
O'Flaherty JT et al. | 1-O-Alkyl-sn-glyceryl-3-phosphorylcholines: a novel class of neutrophil stimulants. | 1981 | Am. J. Pathol. | pmid:7223864 |
O'Flaherty JT et al. | Substances which aggregate neutrophils. Mechanism of action. | 1978 | Am. J. Pathol. | pmid:356621 |
Hsu LS and Becker EL | Volume changes induced in rabbit polymorphonuclear leukocytes by chemotactic factor and cytochalasin B. | 1975 | Am. J. Pathol. | pmid:1180327 |
Ulevitch RJ et al. | Hyperexpression of interferon-gamma-induced MHC class II genes associated with reorganization of the cytoskeleton. | 1991 | Am. J. Pathol. | pmid:1907805 |
Lanni C and Becker EL | Release of phospholipase A2 activity from rabbit peritoneal neutrophils by f-Met-Leu-Phe. | 1983 | Am. J. Pathol. | pmid:6624881 |
Ogawa H et al. | Comparative study of eosinophil and neutrophil chemotaxis and enzyme release. | 1981 | Am. J. Pathol. | pmid:7294162 |
O'Flaherty JT et al. | Role of extracellular calcium and neutrophil degranulation responses to 1-O-alkyl-2-O-acetyl-sn-glycero-3-phosphocholine. | 1981 | Am. J. Pathol. | pmid:6271016 |
Holland JA et al. | Atherogenic levels of low-density lipoprotein increase endocytotic activity in cultured human endothelial cells. | 1992 | Am. J. Pathol. | pmid:1546741 |
Mease AD et al. | Irreversible neutrophil aggregation. A mechanism of decreased newborn neutrophil chemotactic response. | 1981 | Am. J. Pathol. | pmid:7258298 |
White JG and Rao GH | Microtubule coils versus the surface membrane cytoskeleton in maintenance and restoration of platelet discoid shape. | 1998 | Am. J. Pathol. | pmid:9466587 |
Mukherjee C and Lynn WS | Role of ions and extracellular protein in leukocyte motility and membrane ruffling. | 1978 | Am. J. Pathol. | pmid:717536 |
Webster RO et al. | Enhancement of human polymorphonuclear leukocyte adherence to plastic and endothelium by phorbol myristate acetate. Comparison with human C5a. | 1986 | Am. J. Pathol. | pmid:3789092 |
Ginsberg M et al. | Mechanisms of platelet response to monosodium urate crystals. | 1979 | Am. J. Pathol. | pmid:426039 |
White JG et al. | Glycoprotein Ib is homogeneously distributed on external and internal membranes of resting platelets. | 1999 | Am. J. Pathol. | pmid:10595941 |