CYTOCHALASIN B is a lipid of Polyketides (PK) class. Cytochalasin b is associated with abnormalities such as Renal tubular disorder and Chagas Disease. The involved functions are known as Membrane Protein Traffic, inhibitors, Metabolic Inhibition, Biochemical Pathway and Increased Sensitivy. Cytochalasin b often locates in Cytoplasmic matrix, Plasma membrane, Microtubules, Extracellular and Protoplasm. The associated genes with CYTOCHALASIN B are SLC2A2 gene, PFDN5 gene, SLC2A1 gene, OMG gene and SPEN gene. The related lipids are Steroids, Lipopolysaccharides and Liposomes. The related experimental models are Xenograft Model.
To understand associated biological information of CYTOCHALASIN B, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
CYTOCHALASIN B is suspected in Renal tubular disorder, Chagas Disease and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with CYTOCHALASIN B
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
Xenograft Model are used in the study 'Endofacial competitive inhibition of the glucose transporter 1 activity by gossypol.' (Pérez A et al., 2009).
Model | Cross reference | Weighted score | Related literatures |
---|
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Coderre PE et al. | Rapid substrate translocation by the multisubunit, erythroid glucose transporter requires subunit associations but not cooperative ligand binding. | 1995 | Biochemistry | pmid:7626647 |
Connolly TJ et al. | Effects of bilayer cholesterol on human erythrocyte hexose transport protein activity in synthetic lecithin bilayers. | 1985 | Biochemistry | pmid:4040391 |
Mrotek JJ and Hall PF | Response of adrenal tumor cells to adrenocorticotropin: site of inhibition by cytochalasin B. | 1977 | Biochemistry | pmid:196628 |
Baldwin SA et al. | Monosaccharide transporter of the human erythrocyte. Characterization of an improved preparation. | 1982 | Biochemistry | pmid:6890381 |
Cloherty EK et al. | The red blood cell glucose transporter presents multiple, nucleotide-sensitive sugar exit sites. | 2001 | Biochemistry | pmid:11747430 |
Carruthers A and Melchior DL | Human erythrocyte hexose transporter activity is governed by bilayer lipid composition in reconstituted vesicles. | 1984 | Biochemistry | pmid:6543323 |
May JM et al. | Tryptic digestion of the human erythrocyte glucose transporter: effects on ligand binding and tryptophan fluorescence. | 1993 | Biochemistry | pmid:8373759 |
Burant CF and Bell GI | Mammalian facilitative glucose transporters: evidence for similar substrate recognition sites in functionally monomeric proteins. | 1992 | Biochemistry | pmid:1420159 |
Hayden SM et al. | Analysis of the interactions of actin depolymerizing factor with G- and F-actin. | 1993 | Biochemistry | pmid:8399168 |
Heard KS et al. | ATP-dependent substrate occlusion by the human erythrocyte sugar transporter. | 2000 | Biochemistry | pmid:10715121 |
King AP et al. | Cytochalasin B interferes with conformational changes of the human erythrocyte glucose transporter induced by internal and external sugar binding. | 1991 | Biochemistry | pmid:1747373 |
Hebert DN and Carruthers A | Cholate-solubilized erythrocyte glucose transporters exist as a mixture of homodimers and homotetramers. | 1991 | Biochemistry | pmid:2029513 |
Gorga FR and Lienhard GE | Equilibria and kinetics of ligand binding to the human erythrocyte glucose transporter. Evidence for an alternating conformation model for transport. | 1981 | Biochemistry | pmid:7295669 |
Axelrod JD and Pilch PF | Unique cytochalasin B binding characteristics of the hepatic glucose carrier. | 1983 | Biochemistry | pmid:6683102 |
Shanahan MF | Characterization of cytochalasin B photoincorporation into human erythrocyte D-glucose transporter and F-actin. | 1983 | Biochemistry | pmid:6683567 |
Bloch R | Inhibition of glucose transport in the human erythrocyte by cytochalasin B. | 1973 | Biochemistry | pmid:4773858 |
Carruthers A and Helgerson AL | Inhibitions of sugar transport produced by ligands binding at opposite sides of the membrane. Evidence for simultaneous occupation of the carrier by maltose and cytochalasin B. | 1991 | Biochemistry | pmid:2018762 |
Epand RF et al. | Glucose-induced thermal stabilization of the native conformation of GLUT 1. | 1999 | Biochemistry | pmid:9890928 |
Rampal AL et al. | Structure of cytochalasins and cytochalasin B binding sites in human erythrocyte membranes. | 1980 | Biochemistry | pmid:7356953 |
Lachaal M et al. | Cadmium increases GLUT1 substrate binding affinity in vitro while reducing its cytochalasin B binding affinity. | 1996 | Biochemistry | pmid:8942661 |
Himmelreich U et al. | 13C NMR studies of vitamin C transport and its redox cycling in human erythrocytes. | 1998 | Biochemistry | pmid:9585573 |
Robichaud T et al. | Determinants of ligand binding affinity and cooperativity at the GLUT1 endofacial site. | 2011 | Biochemistry | pmid:21384913 |
Brekkan E et al. | Immobilized membrane vesicle or proteoliposome affinity chromatography. Frontal analysis of interactions of cytochalasin B and D-glucose with the human red cell glucose transporter. | 1996 | Biochemistry | pmid:8810921 |
May JM et al. | Localization of a reactive exofacial sulfhydryl on the glucose carrier of human erythrocytes. | 1990 | Biochemistry | pmid:2261480 |
Sampath P and Pollard TD | Effects of cytochalasin, phalloidin, and pH on the elongation of actin filaments. | 1991 | Biochemistry | pmid:1899622 |
Sogin DC and Hinkle PC | Binding of cytochalasin B to human erythrocyte glucose transporter. | 1980 | Biochemistry | pmid:7192569 |
Carruthers A | Anomalous asymmetric kinetics of human red cell hexose transfer: role of cytosolic adenosine 5'-triphosphate. | 1986 | Biochemistry | pmid:3718945 |
Anichini E et al. | Interaction of urokinase-type plasminogen activator with its receptor rapidly induces activation of glucose transporters. | 1997 | Biochemistry | pmid:9115983 |
Hamill S et al. | The human erythrocyte sugar transporter presents two sugar import sites. | 1999 | Biochemistry | pmid:10606533 |
Baldwin SA et al. | Purification of the cytochalasin B binding component of the human erythrocyte monosaccharide transport system. | 1979 | Biochim. Biophys. Acta | pmid:435493 |
Bleken A et al. | Uptake and degradation of desialylated luteinizing hormone by suspended hepatocytes. | 1982 | Biochim. Biophys. Acta | pmid:6177349 |
Kasahara T and Kasahara M | Characterization of rat Glut4 glucose transporter expressed in the yeast Saccharomyces cerevisiae: comparison with Glut1 glucose transporter. | 1997 | Biochim. Biophys. Acta | pmid:9059504 |
Kitagawa K et al. | Analysis of hexose transport in untransformed and sarcoma virus-transformed mouse 3T3 cells by photoaffinity binding of cytochalasin B. | 1985 | Biochim. Biophys. Acta | pmid:2998464 |
Miller NE and Yin JA | Effects of cytochalasin B on low-density lipoproteins metabolism by cultured human fibroblasts. | 1978 | Biochim. Biophys. Acta | pmid:210829 |
Schwendener RA et al. | The effects of charge and size on the interaction of unilamellar liposomes with macrophages. | 1984 | Biochim. Biophys. Acta | pmid:6712952 |
Regoeczi E et al. | Elimination of asialofetuin and asialoorosomucoid by the intact rat. Quantitative aspects of the hepatic clearance mechanism. | 1978 | Biochim. Biophys. Acta | pmid:78729 |
Shefcyk J et al. | Phloretin is a potent inhibitor of rabbit neutrophil activation by chemotactic factors. | 1983 | Biochim. Biophys. Acta | pmid:6830775 |
Sobrino F et al. | Short-term stimulation by adenosine of basal and insulin-induced glycogen synthesis in rat adipose tissue. | 1986 | Biochim. Biophys. Acta | pmid:3002488 |
Niessen HW and Verhoeven AJ | Role of protein phosphorylation in the degranulation of electropermeabilized human neutrophils. | 1994 | Biochim. Biophys. Acta | pmid:8086498 |
Morishige H et al. | In vitro cytostatic effect of TNF (tumor necrosis factor) entrapped in immunoliposomes on cells normally insensitive to TNF. | 1993 | Biochim. Biophys. Acta | pmid:8357820 |
Cuppoletti J et al. | Cytochalasin B binding to Ehrlich ascites tumor cells and its relationship to glucose carrier. | 1981 | Biochim. Biophys. Acta | pmid:7284364 |
Di Virgilio F and Gomperts BD | Ionophore monensin induces Na+-dependent secretion from rabbit neutrophils. requirement for intracellular Ca2+ stores. | 1983 | Biochim. Biophys. Acta | pmid:6626584 |
Leung YM et al. | Calyculin A-induced endothelial cell shape changes are independent of [Ca(2+)](i) elevation and may involve actin polymerization. | 2002 | Biochim. Biophys. Acta | pmid:12007785 |
Kimura Y et al. | Effects of baicalein on leukotriene biosynthesis and degranulation in human polymorphonuclear leukocytes. | 1987 | Biochim. Biophys. Acta | pmid:2825795 |
Loizzi RF et al. | Inhibition by cyclic AMP of lactose production in lactating guinea pig mammary gland slices. | 1975 | Biochim. Biophys. Acta | pmid:164955 |
Gross RL et al. | Characterization of cytochalasin B binding to adult rat liver parenchymal cells in primary culture. | 1980 | Biochim. Biophys. Acta | pmid:7437425 |
Bihler I et al. | Sarcolemmal glucose transport in Ca2+-tolerant myocytes from adult rat heart. Calcium dependence of insulin action. | 1985 | Biochim. Biophys. Acta | pmid:3881135 |
Bennett JP et al. | Use of cytochalasin B to distinguish between early and late events in neutrophil activation. | 1980 | Biochim. Biophys. Acta | pmid:6251879 |
Horne MK and Hart JS | Cytochalasin inhibition of hexose transport by platelets. | 1987 | Biochim. Biophys. Acta | pmid:3651466 |
Leach GJ and Spitzer JA | Endotoxin-induced alterations in glucose transport in isolated adipocytes. | 1981 | Biochim. Biophys. Acta | pmid:7028118 |