CYTOCHALASIN B

CYTOCHALASIN B is a lipid of Polyketides (PK) class. Cytochalasin b is associated with abnormalities such as Renal tubular disorder and Chagas Disease. The involved functions are known as Membrane Protein Traffic, inhibitors, Metabolic Inhibition, Biochemical Pathway and Increased Sensitivy. Cytochalasin b often locates in Cytoplasmic matrix, Plasma membrane, Microtubules, Extracellular and Protoplasm. The associated genes with CYTOCHALASIN B are SLC2A2 gene, PFDN5 gene, SLC2A1 gene, OMG gene and SPEN gene. The related lipids are Steroids, Lipopolysaccharides and Liposomes. The related experimental models are Xenograft Model.

Cross Reference

Introduction

To understand associated biological information of CYTOCHALASIN B, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with CYTOCHALASIN B?

CYTOCHALASIN B is suspected in Renal tubular disorder, Chagas Disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with CYTOCHALASIN B

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Tuberculosis D014376 20 associated lipids
Uremia D014511 33 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Adenocarcinoma D000230 166 associated lipids
Dermatitis, Contact D003877 59 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Lung Neoplasms D008175 171 associated lipids
Wounds and Injuries D014947 20 associated lipids
Adenoma, Islet Cell D007516 7 associated lipids
Insulinoma D007340 28 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Inflammation D007249 119 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetic Nephropathies D003928 39 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Body Weight D001835 333 associated lipids
Foreign-Body Reaction D005549 10 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with CYTOCHALASIN B

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with CYTOCHALASIN B?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with CYTOCHALASIN B?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with CYTOCHALASIN B?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with CYTOCHALASIN B?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with CYTOCHALASIN B?

Xenograft Model

Xenograft Model are used in the study 'Endofacial competitive inhibition of the glucose transporter 1 activity by gossypol.' (Pérez A et al., 2009).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with CYTOCHALASIN B

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Authors Title Published Journal PubMed Link
Kloc M et al. Elaboration of the messenger transport organizer pathway for localization of RNA to the vegetal cortex of Xenopus oocytes. 1996 Dev. Biol. pmid:8948579
Scott D et al. Dose-rate sparing for micronucleus induction in lymphocytes of controls and ataxia-telangiectasia heterozygotes exposed to 60Co gamma-irradiation in vitro. 1996 Int. J. Radiat. Biol. pmid:8947533
Lichtman SN et al. Endocytosis and Ca2+ are required for endotoxin-stimulated TNF-alpha release by rat Kupffer cells. 1996 Am. J. Physiol. pmid:8944708
Fierro IM et al. The involvement of nitric oxide in the anti-Candida albicans activity of rat neutrophils. 1996 Immunology pmid:8943729
Finger EB et al. A differential role for cell shape in neutrophil tethering and rolling on endothelial selectins under flow. 1996 J. Immunol. pmid:8943418
Lachaal M et al. Cadmium increases GLUT1 substrate binding affinity in vitro while reducing its cytochalasin B binding affinity. 1996 Biochemistry pmid:8942661
Masamune S et al. Activation of thiol esters. Partial synthesis of cytochalasins A and B. 1977 J. Am. Chem. Soc. pmid:893906
Stournaras C et al. Altered actin polymerization dynamics in various malignant cell types: evidence for differential sensitivity to cytochalasin B. 1996 Biochem. Pharmacol. pmid:8937443
Shanahan MF and Czech MP Partial purification of the D-glucose transport system in rat adipocyte plasma membranes. 1977 J. Biol. Chem. pmid:893428
Rodriguez-Linares B and Cano E In-vitro platelet responses to arachidonic acid in the rat. 1995 J. Pharm. Pharmacol. pmid:8932686
Ehrhardt AG et al. A large-conductance K+ channel that is inhibited by the cytoskeleton in the smooth muscle cell line DDT1 MF-2. 1996 J. Physiol. (Lond.) pmid:8930834
Peralta Soler A et al. Tissue remodeling during tumor necrosis factor-induced apoptosis in LLC-PK1 renal epithelial cells. 1996 Am. J. Physiol. pmid:8928850
Abu-Hakima R and Davey KG The action of juvenile hormone on follicle cells of Rhodnius prolixus in vitro: the effect of colchicine and cytochalasin B. 1977 Gen. Comp. Endocrinol. pmid:892420
Gervasi DC et al. Carbohydrate-mediated regulation of matrix metalloproteinase-2 activation in normal human fibroblasts and fibrosarcoma cells. 1996 Biochem. Biophys. Res. Commun. pmid:8920947
Nagai R and Kamiya N Differential treatment of Chara cells with cytochalasin B with special reference to its effect on cytoplasmic streaming. 1977 Exp. Cell Res. pmid:891633
Kim NH et al. Microfilament assembly and cortical granule distribution during maturation, parthenogenetic activation and fertilisation in the porcine oocyte. 1996 Zygote pmid:8913028
Marder O et al. Effect of interleukin-1 alpha, interleukin-1 beta and tumor necrosis factor-alpha on the intracellular fluorescein fluorescence polarization of human lung fibroblasts. 1996 Pathobiology pmid:8910920
Dusi S et al. Mechanisms of stimulation of the respiratory burst by TNF in nonadherent neutrophils: its independence of lipidic transmembrane signaling and dependence on protein tyrosine phosphorylation and cytoskeleton. 1996 J. Immunol. pmid:8906841
Ferrara CM et al. Exercise training and the glucose transport system in obese SHHF/Mcc-fa(cp) rats. 1996 J. Appl. Physiol. pmid:8904585
Peterson RN et al. Binding of cytochalasin B to hexose transport sites on human spermatozoa and inhibition of binding by purines. 1977 Biol. Reprod. pmid:889991