CYTOCHALASIN B

CYTOCHALASIN B is a lipid of Polyketides (PK) class. Cytochalasin b is associated with abnormalities such as Renal tubular disorder and Chagas Disease. The involved functions are known as Membrane Protein Traffic, inhibitors, Metabolic Inhibition, Biochemical Pathway and Increased Sensitivy. Cytochalasin b often locates in Cytoplasmic matrix, Plasma membrane, Microtubules, Extracellular and Protoplasm. The associated genes with CYTOCHALASIN B are SLC2A2 gene, PFDN5 gene, SLC2A1 gene, OMG gene and SPEN gene. The related lipids are Steroids, Lipopolysaccharides and Liposomes. The related experimental models are Xenograft Model.

Cross Reference

Introduction

To understand associated biological information of CYTOCHALASIN B, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with CYTOCHALASIN B?

CYTOCHALASIN B is suspected in Renal tubular disorder, Chagas Disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with CYTOCHALASIN B

MeSH term MeSH ID Detail
Erythroblastosis, Fetal D004899 2 associated lipids
CREST Syndrome D017675 2 associated lipids
Factor XII Deficiency D005175 2 associated lipids
Wiskott-Aldrich Syndrome D014923 3 associated lipids
Pharyngeal Neoplasms D010610 4 associated lipids
Pituitary Neoplasms D010911 4 associated lipids
Coronavirus Infections D018352 4 associated lipids
Granulomatous Disease, Chronic D006105 4 associated lipids
Chancroid D002602 4 associated lipids
Systemic Inflammatory Response Syndrome D018746 4 associated lipids
Granulomatosis with Polyangiitis D014890 5 associated lipids
Galactosemias D005693 5 associated lipids
Infectious Mononucleosis D007244 5 associated lipids
Ataxia Telangiectasia D001260 6 associated lipids
Trisomy D014314 6 associated lipids
Adenoma, Islet Cell D007516 7 associated lipids
Lymphoproliferative Disorders D008232 7 associated lipids
Aggressive Periodontitis D010520 8 associated lipids
Carbon Monoxide Poisoning D002249 9 associated lipids
Chondrosarcoma D002813 9 associated lipids
Foreign-Body Reaction D005549 10 associated lipids
Lymphoma, T-Cell D016399 11 associated lipids
Congenital Abnormalities D000013 11 associated lipids
Eye Diseases D005128 12 associated lipids
Hypoglycemia D007003 13 associated lipids
Glucose Intolerance D018149 13 associated lipids
Neutropenia D009503 15 associated lipids
Tongue Neoplasms D014062 15 associated lipids
Thrombocytopenia D013921 15 associated lipids
Burkitt Lymphoma D002051 15 associated lipids
Thymus Neoplasms D013953 15 associated lipids
Leukemia, Myelogenous, Chronic, BCR-ABL Positive D015464 17 associated lipids
Lymphoma D008223 18 associated lipids
Leukemia, Lymphoid D007945 18 associated lipids
Tuberculosis D014376 20 associated lipids
Wounds and Injuries D014947 20 associated lipids
Anemia D000740 21 associated lipids
Hypoxia-Ischemia, Brain D020925 22 associated lipids
Malaria, Falciparum D016778 22 associated lipids
Medulloblastoma D008527 22 associated lipids
Carcinoma 256, Walker D002279 22 associated lipids
Birth Weight D001724 23 associated lipids
Lymphoma, B-Cell D016393 24 associated lipids
Cell Transformation, Viral D002472 26 associated lipids
Hyperinsulinism D006946 27 associated lipids
Insulinoma D007340 28 associated lipids
Kidney Diseases D007674 29 associated lipids
Endometrial Neoplasms D016889 30 associated lipids
Uremia D014511 33 associated lipids
Micronuclei, Chromosome-Defective D048629 33 associated lipids
Per page 10 20 50 100 | Total 79

PubChem Associated disorders and diseases

What pathways are associated with CYTOCHALASIN B

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with CYTOCHALASIN B?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with CYTOCHALASIN B?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with CYTOCHALASIN B?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with CYTOCHALASIN B?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with CYTOCHALASIN B?

Xenograft Model

Xenograft Model are used in the study 'Endofacial competitive inhibition of the glucose transporter 1 activity by gossypol.' (Pérez A et al., 2009).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with CYTOCHALASIN B

Download all related citations
Per page 10 20 50 100 | Total 4982
Authors Title Published Journal PubMed Link
Barja F and Turian G Cytochalasin B-sensitive actin-mediated nuclear RNA export in germinating conidia of Neurospora crassa. 1994 Cell Biol. Int. pmid:8000364
Cho SJ et al. Structure and dynamics of the fusion pore in live cells. 2002 Cell Biol. Int. pmid:11779219
Volobuyeva OV et al. Influence of inhibitors of cytoskeleton proteins on water exchange of wheat roots under the after-action of water stress. 2000 Cell Biol. Int. pmid:10860574
Abdrakhimova YR et al. Influence of cytoskeletal agents on the respiratory electron transport pathways in the cells of winter wheat leaves. 2000 Cell Biol. Int. pmid:10860575
Roy SG Role of stress fibers in the association of intermediate filaments with microtubules in fibroblast cells. 1993 Cell Biol. Int. pmid:8374596
Song Z et al. Unpolymerized nuclear actin is involved in the activation of CSF-1 gene transcription. 2004 Cell Biol. Int. pmid:15261158
Katsaros C et al. F-actin cytoskeleton and cell wall morphogenesis in brown algae. 2003 Cell Biol. Int. pmid:12681310
Court JB et al. The survival of cytochalasin-induced polykaryons following exposure to cytotoxic agents. 1993 Cell Biol. Int. pmid:8513297
Rotsch C et al. AFM imaging and elasticity measurements on living rat liver macrophages. 1997 Cell Biol. Int. pmid:9817809
Rebecchi IM et al. Oxidative metabolism and release of myeloperoxidase from polymorphonuclear leukocytes obtained from blood sedimentation in a Ficoll-Hypaque gradient. 2000 Cell Biochem. Funct. pmid:10814971
Malaisse WJ et al. Pancreatic fate of D-[3H] mannoheptulose. 2001 Cell Biochem. Funct. pmid:11494306
Fjose A and Pryme IF Altered distribution profiles of endoplasmic reticulum subfractions after incubation of Krebs II ascites cells with different concentrations of cytochalasin B. 1984 Cell Biochem. Funct. pmid:6540633
Shock A and Baum H Inactivation of alpha-1-proteinase inhibitor in serum by stimulated human polymorphonuclear leucocytes. Evidence for a myeloperoxidase-dependent mechanism. 1988 Cell Biochem. Funct. pmid:2832092
Cetik S et al. Uptake and metabolism of D-glucose in isolated acinar and ductal cells from rat submandibular glands. 2014 Cell Biochem. Funct. pmid:24888554
Malaisse WJ et al. Effect of cytochalasin B on glucose uptake, utilization, oxidation and insulinotropic action in tumoral insulin-producing cells. 1987 Cell Biochem. Funct. pmid:3038362
Evangelisti R et al. Modulation of phenotypic expression of fibroblasts by alteration of the cytoskeleton. 1995 Cell Biochem. Funct. pmid:7720189
Torti M et al. Stimulation of human platelets with concanavalin A involves phospholipase C activation. 1992 Cell Biochem. Funct. pmid:1576730
Theodoropoulos PA et al. Normal and Ha-ras-1 oncogene transformed Buffalo rat liver (BRL) cells show differential resistance to cytoskeletal protein inhibitors. 1992 Cell Biochem. Funct. pmid:1473269
Katsantonis J et al. Differences in the G/total actin ratio and microfilament stability between normal and malignant human keratinocytes. 1994 Cell Biochem. Funct. pmid:7834816
Nakada MT et al. Neutralization of TNF by the antibody cA2 reveals differential regulation of adhesion molecule expression on TNF-activated endothelial cells. 1998 Cell Adhes. Commun. pmid:9791729
MacLean-Fletcher S and Pollard TD Mechanism of action of cytochalasin B on actin. 1980 Cell pmid:6893016
Grumet M and Lin S A platelet inhibitor protein with cytochalasin-like activity against actin polymerization in vitro. 1980 Cell pmid:6893297
Storrie B and Edelson PJ Distribution of concanavalin A in fibroblasts: direct endocytosis versus surface capping. 1977 Cell pmid:195744
Wang YL and Taylor DL Probing the dynamic equilibrium of actin polymerization by fluorescence energy transfer. 1981 Cell pmid:6101197
Kreis TE and Birchmeier W Stress fiber sarcomeres of fibroblasts are contractile. 1980 Cell pmid:6893813
Toyama S and Toyama S A variant form of beta-actin in a mutant of KB cells resistant to cytochalasin B. 1984 Cell pmid:6202424
Ghosh A et al. Inhibition of mycoplasma cell division by cytochalasin B. 1978 Cell pmid:620423
Carroll RC et al. Separable assembly of platelet pseudopodal and contractile cytoskeletons. 1982 Cell pmid:6890413
Lenk R and Penman S The cytoskeletal framework and poliovirus metabolism. 1979 Cell pmid:222454
Maness PF and Walsh RC Dihydrocytochalasin B disorganizes actin cytoarchitecture and inhibits initiation of DNA synthesis in 3T3 cells. 1982 Cell pmid:6215122
Hatzfeld J and Buttin G Temperature-sensitive cell cycle mutants: a chinese hamster cell line with a reversible block in cytokinesis. 1975 Cell pmid:1170022
Pike MC et al. Influence of cytoskeletal assembly on phosphatidylcholine synthesis in intact phagocytic cells. 1980 Cell pmid:7190071
Stoker M The effects of topoinhibition and cytochalasin B on metabolic cooperation. 1975 Cell pmid:1182805
Lenk R et al. A cytoskeletal structure with associated polyribosomes obtained from HeLa cells. 1977 Cell pmid:837445
Levitt D and Cooper MD Mouse pre-B cells synthesize and secrete mu heavy chains but not light chains. 1980 Cell pmid:6767547
Pollack R et al. Properties of enucleated cells. II. Characteristic overlapping of transformed cells is reestablished by enucleates. 1974 Cell pmid:4370294
Shields R and Pollock K The adhesion of BHK and PyBHK cells to the substratum. 1974 Cell pmid:4370432
Manel N et al. The ubiquitous glucose transporter GLUT-1 is a receptor for HTLV. 2003 Cell pmid:14622599
Hynes RO and Destree AT 10 nm filaments in normal and transformed cells. 1978 Cell pmid:340048
Gordon WE et al. Characterization of the intermediate (10 nm) filaments of cultured cells using an autoimmune rabbit antiserum. 1978 Cell pmid:342115
Ehrnst A and Sundqvist KG Polar appearance and nonligand induced spreading of measles virus hemagglutinin at the surface of chronically infected cells. 1975 Cell pmid:808272
Laufer JS et al. Segregation of developmental potential in early embryos of Caenorhabditis elegans. 1980 Cell pmid:7363324
Weber MJ et al. Decreased adherence to the substrate in Rous sarcoma virus-transformed chicken embryo fibroblasts. 1977 Cell pmid:189934
Lambert CR et al. Local drug delivery. 1997 Cathet Cardiovasc Diagn pmid:9213019
Kocisová J and Srám RJ [The micronuclei detection test in stimulated human peripheral lymphocytes using cytochalasin B]. 1989 Cas. Lek. Cesk. pmid:2736600
Kubzová E et al. [Use of cytochalasin B in the micronucleus test in human peripheral lymphocytes]. 1990 Cas. Lek. Cesk. pmid:2257572
Dick DJ and Lab MJ Mechanical modulation of stretch-induced premature ventricular beats: induction of mechanoelectric adaptation period. 1998 Cardiovasc. Res. pmid:9683920
Pieper GM and Dondlinger L Glucose elevations alter bradykinin-stimulated intracellular calcium accumulation in cultured endothelial cells. 1997 Cardiovasc. Res. pmid:9217887
Takeuchi T and Morimoto K Crocidolite asbestos increased 8-hydroxydeoxyguanosine levels in cellular DNA of a human promyelocytic leukemia cell line, HL60. 1994 Carcinogenesis pmid:8149473
Ochalek T et al. Correlation between cell deformability and metastatic potential in B16-F1 melanoma cell variants. 1988 Cancer Res. pmid:3409238
Varani J and Fantone JC Phorbol myristate acetate-induced adherence of Walker 256 carcinosarcoma cells. 1982 Cancer Res. pmid:7053849
Somers KD and Murphey MM Multinucleation in response to cytochalasin B: a common feature in several human tumor cell lines. 1982 Cancer Res. pmid:6177397
Mak WW et al. Accumulation of actin microfilaments in adult rat hepatocytes cultured on collagen gel/nylon mesh. 1980 Cancer Res. pmid:6893678
Bystryn JC and Perlstein J Autocatabolism of surface macromolecules shed by human melanoma cells. 1982 Cancer Res. pmid:7074605
Delicado E et al. Effects of insulin on glucose transporters and metabolic patterns in Harding-Passey melanoma cells. 1986 Cancer Res. pmid:3089579
Asch BB et al. Comparative responses of normal and malignant mouse mammary cells to modulation of surface properties. 1980 Cancer Res. pmid:6248204
Zhang X et al. Microfilament depletion and circumvention of multiple drug resistance by sphinxolides. 1997 Cancer Res. pmid:9288783
Bousquet PF et al. Effects of cytochalasin B in culture and in vivo on murine Madison 109 lung carcinoma and on B16 melanoma. 1990 Cancer Res. pmid:2302708
Plagemann PG and Erbe J Transport and metabolism of glucosamine by cultured Novikoff rat hepatoma cells and effects on nucleotide pools. 1973 Cancer Res. pmid:4347714
O'Neill FJ and Renzetti L In vitro growth control phenotypes of transformed rodent cells prior to and following tumorigenesis. 1983 Cancer Res. pmid:6848175
O'Neill FJ Selective destruction of cultured tumor cells with uncontrolled nuclear division by cytochalasin B and cytosine arabinoside. 1975 Cancer Res. pmid:1182703
Smith BM et al. Calcium modulation of phorbol ester-induced alterations in murine macrophage morphology. 1983 Cancer Res. pmid:6189598
Tan P and Auersperg N Effects of the antineoplastic alkaloid acronycine on the ultrastructure and growth patterns of cultured cells. 1973 Cancer Res. pmid:4355024
Ebisuzaki K et al. Temporal mapping of the differentiation pathway of the murine erythroleukemia cell. 1991 Cancer Res. pmid:1998957
Marchok AC and Martin DH Sequential appearance of anchorage independence, uncontrolled nuclear division and tumorigenicity in 7,12-dimethylbenz(a)anthracene-exposed rat tracheal epithelial cells. 1987 Cancer Res. pmid:3107810
Ronquist G and Agren GK A Mg2+- and Ca2+-stimulated adenosine triphosphatase at the outer surface of Ehrlich ascites tumor cells. 1975 Cancer Res. pmid:124205
Shibamoto Y and Streffer C Estimation of the dividing fraction and potential doubling time of tumors using cytochalasin B. 1991 Cancer Res. pmid:1913638
Bosman C et al. Phagocytosis of nerve growth factor-coated erythrocytes in neuroblastoma rosette-forming cells. 1975 Cancer Res. pmid:1116148
O'Neill FJ Loss of controlled nuclear division in BHK21 cells passed in vivo. 1976 Cancer Res. pmid:944618
Cotter TG et al. Microfilament-disrupting agents prevent the formation of apoptotic bodies in tumor cells undergoing apoptosis. 1992 Cancer Res. pmid:1737363
O'Brien TG et al. The effect of colchicine on the induction of ornithine decarboxylase by 12-O-tetradecanoyl-phorbol-13-acetate. 1976 Cancer Res. pmid:954002
Russo J et al. Expression of phenotypical changes by human breast epithelial cells treated with carcinogens in vitro. 1988 Cancer Res. pmid:3129189
Tsiftsoglou AS and Sartorelli AC Dimethyl sulfoxide-induced differentiation of Friend erythroleukemia cells in the absence of cytokinesis. 1979 Cancer Res. pmid:289437
Medina D et al. Distinction between preneopastic and neoplastic mammary cell populations in vitro by cytochalasin B-induced multinucleation. 1980 Cancer Res. pmid:7356516
Butler WB et al. Relation of in vitro properties to tumorigenicity for a series of sublines of the human breast cancer cell line MCF-7. 1986 Cancer Res. pmid:3779650
Kelly F Chromosome analysis of a simian virus 40-transformed mouse cell line and two variant sublines that are resistant to cytochalasin B1. 1975 Cancer Res. pmid:164282
Yan B et al. Tumor necrosis factor-alpha is a potent endogenous mutagen that promotes cellular transformation. 2006 Cancer Res. pmid:17178846
Ebina T and Ishida N Inhibition of formation of microtubular paracrystals in HeLa-S3 cells by neocarzinostatin. 1975 Cancer Res. pmid:172232
Wang M and Stearns ME Blocking of collagenase secretion by estramustine during in vitro tumor cell invasion. 1988 Cancer Res. pmid:2846150
Matsui T et al. Effects of calmodulin antagonists and cytochalasins on proliferation and differentiation of human promyelocytic leukemia cell line HL-60. 1985 Cancer Res. pmid:3855282
Somers KD and Murphey MM Multinucleation in the presence of cytochalasin B by RNA tumor virus-transformed cells. 1980 Cancer Res. pmid:6254645
Smith CD et al. Cryptophycin: a new antimicrotubule agent active against drug-resistant cells. 1994 Cancer Res. pmid:7913408
Furcht LT et al. Independent alterations in cell shape and intramembranous particle topography induced by cytochalasin B and colchicine in normal and transformed cells. 1976 Cancer Res. pmid:187328
Steiner MR et al. Differential response of cultured mouse mammary cells of varying tumorigenicity to cytochalasin B. 1978 Cancer Res. pmid:679176
Wertz PW and Mueller GC Rapid stimulation of phospholipid metabolism in bovine lymphocytes by tumor-promoting phorbol esters. 1978 Cancer Res. pmid:679198
Kwong CH and Mueller GC Antagonism of concanavalin A capping in phorbol ester-activated lymphocytes by calmodulin inhibitors and certain amino acid esters. 1982 Cancer Res. pmid:7200397
Smith CD et al. Scytophycins, novel microfilament-depolymerizing agents which circumvent P-glycoprotein-mediated multidrug resistance. 1993 Cancer Res. pmid:8095179
Leung SW et al. Inhibition by N-(phosphonacetyl)-L-aspartate of Ehrlich ascites tumour growth and glucose transport. 1984 Cancer Lett. pmid:6744243
Takeshita H et al. Actin organization associated with the expression of multidrug resistant phenotype in osteosarcoma cells and the effect of actin depolymerization on drug resistance. 1998 Cancer Lett. pmid:9563651
Iwazaki R et al. The role of the cytoskeleton in migration and proliferation of a cultured human gastric cancer cell line using a new metastasis model. 1997 Cancer Lett. pmid:9570371
Lecavalier D and Mackillop WJ The effect of hyperthermia on glucose transport in normal and thermal-tolerant Chinese hamster ovary cells. 1985 Cancer Lett. pmid:4075291
Mozdarani H and Monfared AS Laserthermia enhances the clastogenic effects of antineoplastic agents in aerobic and chronically hypoxic HeLa cells in vitro. 2001 Cancer Lett. pmid:11323094
Trendowski M et al. Preferential enlargement of leukemia cells using cytoskeletal-directed agents and cell cycle growth control parameters to induce sensitivity to low frequency ultrasound. 2015 Cancer Lett. pmid:25667120
Fung KP et al. Suppression of Ehrlich ascites tumor growth in mice by starvation and streptozotocin-induced diabetes. 1985 Cancer Lett. pmid:3902210
Yi M et al. Response of fibroblast cultures from ataxia-telangiectasia patients to oxidative stress. 1990 Cancer Lett. pmid:2208088
Ber R et al. Cell surface antigen expression in cytoplasts and karyoplasts of mouse L cells. 1978 Cancer Lett. pmid:688187
Kuroki H et al. Streptococcal preparation OK-432: a new maturation factor of monocyte-derived dendritic cells for clinical use. 2003 Cancer Immunol. Immunother. pmid:14627128
Bogyo D et al. Cytochalasin-B-induced immunosuppression of murine allogeneic anti-tumor response and the effect of recombinant human interleukin-2. 1991 Cancer Immunol. Immunother. pmid:1901032
Hosari E et al. Microcell-mediated chromosome transfer from human tumor cells to human recipient cells evidenced by premature condensation of the transferred chromosomes. 1986 Cancer Genet. Cytogenet. pmid:3455863
Crossen PE et al. Chromosome abnormalities in chronic lymphocytic leukemia revealed by cytochalasin B and Epstein-Barr virus. 1987 Cancer Genet. Cytogenet. pmid:3038300