CYTOCHALASIN B
CYTOCHALASIN B is a lipid of Polyketides (PK) class. Cytochalasin b is associated with abnormalities such as Renal tubular disorder and Chagas Disease. The involved functions are known as Membrane Protein Traffic, inhibitors, Metabolic Inhibition, Biochemical Pathway and Increased Sensitivy. Cytochalasin b often locates in Cytoplasmic matrix, Plasma membrane, Microtubules, Extracellular and Protoplasm. The associated genes with CYTOCHALASIN B are SLC2A2 gene, PFDN5 gene, SLC2A1 gene, OMG gene and SPEN gene. The related lipids are Steroids, Lipopolysaccharides and Liposomes. The related experimental models are Xenograft Model.
Cross Reference
Introduction
To understand associated biological information of CYTOCHALASIN B, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with CYTOCHALASIN B?
CYTOCHALASIN B is suspected in Renal tubular disorder, Chagas Disease and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with CYTOCHALASIN B
PubChem Associated disorders and diseases
What pathways are associated with CYTOCHALASIN B
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with CYTOCHALASIN B?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with CYTOCHALASIN B?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with CYTOCHALASIN B?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with CYTOCHALASIN B?
Related references are published most in these journals:
- Am. J. Physiol., Cell Physiol. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Biochim. Biophys. Acta (1)
- Others (8)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with CYTOCHALASIN B?
Xenograft Model
Xenograft Model are used in the study 'Endofacial competitive inhibition of the glucose transporter 1 activity by gossypol.' (Pérez A et al., 2009).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with CYTOCHALASIN B
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Meroni SB et al. | Possible involvement of microfilaments in the regulation of Sertoli cell aromatase activity. | 1995 | Mol. Cell. Endocrinol. | pmid:7589787 |
| Netchitailo P et al. | In vitro effect of cytochalasin B on adrenal steroidogenesis in frog. | 1985 | Mol. Cell. Endocrinol. | pmid:4076535 |
| Houdebine LM and Djiane J | Effects of lysomotropic agents, and of microfilament- and microtubule-disrupting drugs on the activation of casein-gene expression by prolactin in the mammary gland. | 1980 | Mol. Cell. Endocrinol. | pmid:6244204 |
| Mason JI and Robidoux WF | Pregnenolone biosynthesis in isolated cells of Snell rat adrenocortical carcinoma 494. | 1978 | Mol. Cell. Endocrinol. | pmid:216596 |
| Djiane J et al. | Effects of lysosomotropic agents, cytochalasin B and colchicine on the "down-regulation" of prolactin receptors in mammary gland explants. | 1980 | Mol. Cell. Endocrinol. | pmid:6247227 |
| Lewitt MS and Baxter RC | Cytochalasin B stimulates insulin-like growth factor-binding protein-1 production by Hep G2 cells. | 1991 | Mol. Cell. Endocrinol. | pmid:1726153 |
| Malaisse WJ et al. | The stimulus-secretion coupling of glucose-induced insulin release XIX. The insulinotropic effect of glyceraldehyde. | 1975 Dec-1976 Jan | Mol. Cell. Endocrinol. | pmid:1107091 |
| Unger J and Van Sande J | Modulation of thyroglobulin release by dog thyroid slices. | 1987 | Mol. Cell. Endocrinol. | pmid:3040494 |
| Debuyser A et al. | Adrenaline inhibition of insulin release: role of cyclic AMP. | 1991 | Mol. Cell. Endocrinol. | pmid:1663876 |
| Bandyopadhyay S et al. | Kaempferol and quercetin stimulate granulocyte-macrophage colony-stimulating factor secretion in human prostate cancer cells. | 2008 | Mol. Cell. Endocrinol. | pmid:18346843 |
| Ulisse S et al. | Thyroid hormone stimulates glucose transport and GLUT1 mRNA in rat Sertoli cells. | 1992 | Mol. Cell. Endocrinol. | pmid:1446785 |
| Drews G et al. | Significance of membrane repolarization and cyclic AMP changes in mouse pancreatic B-cells for the inhibition of insulin release by galanin. | 1994 | Mol. Cell. Endocrinol. | pmid:7529734 |
| Horuk R and Olefsky JM | Post-binding events in insulin action. | 1985 | Mol. Cell. Endocrinol. | pmid:3896892 |
| Chen LM and Auersperg N | Response to ACTH and dibutyryl cyclic AMP by enucleated adrenocortical tumor cells. | 1976 | Mol. Cell. Endocrinol. | pmid:177319 |
| Gaertner U et al. | Regulation of glycogen synthase interconversion in cultured muscle cells: actions of insulin, calcium, ionophore A 23187 and cytochalasin B. | 1977 | Mol. Cell. Endocrinol. | pmid:407113 |
| Clark S et al. | Effect of temperature on phospholipase C induced alterations in insulin binding. | 1981 | Mol. Cell. Endocrinol. | pmid:7028538 |
| Bethea CL and Kozak SL | Further characterization of substratum influence on PC12 cell shape and dopamine processing. | 1985 | Mol. Cell. Endocrinol. | pmid:4029503 |
| Song J et al. | Cytoskeletal reorganization during the formation of oligodendrocyte processes and branches. | 2001 | Mol. Cell. Neurosci. | pmid:11312599 |
| Annies M et al. | Clustering transmembrane-agrin induces filopodia-like processes on axons and dendrites. | 2006 | Mol. Cell. Neurosci. | pmid:16364653 |
| Schevzov G et al. | Tropomyosin localization reveals distinct populations of microfilaments in neurites and growth cones. | 1997 | Mol. Cell. Neurosci. | pmid:9143561 |
| Wu X et al. | Cloning and characterization of glucose transporter 11, a novel sugar transporter that is alternatively spliced in various tissues. | 2002 | Mol. Genet. Metab. | pmid:12175779 |
| Liu DY et al. | An anti-actin monoclonal antibody inhibits the zona pellucida-induced acrosome reaction and hyperactivated motility of human sperm. | 2002 | Mol. Hum. Reprod. | pmid:11756568 |
| Correia-Branco A et al. | Xanthohumol impairs glucose uptake by a human first-trimester extravillous trophoblast cell line (HTR-8/SVneo cells) and impacts the process of placentation. | 2015 | Mol. Hum. Reprod. | pmid:26194608 |
| Zreik TG et al. | Identification and characterization of an ascorbic acid transporter in human granulosa-lutein cells. | 1999 | Mol. Hum. Reprod. | pmid:10321800 |
| Alikani M et al. | Cytoplasmic fragmentation in activated eggs occurs in the cytokinetic phase of the cell cycle, in lieu of normal cytokinesis, and in response to cytoskeletal disorder. | 2005 | Mol. Hum. Reprod. | pmid:15863451 |
| Zhou GB and Li N | Cryopreservation of porcine oocytes: recent advances. | 2009 | Mol. Hum. Reprod. | pmid:19251762 |
| Liu DY et al. | An important role of actin polymerization in the human zona pellucida-induced acrosome reaction. | 1999 | Mol. Hum. Reprod. | pmid:10508222 |
| Imamichi T et al. | Different abilities of two types of Fc gamma receptor on guinea-pig macrophages to trigger the intracellular Ca2+ mobilization and O2- generation. | 1990 | Mol. Immunol. | pmid:2145507 |
| Thrall RS et al. | Membrane protein alterations in the neutrophil in response to chemotactic factors. | 1980 | Mol. Immunol. | pmid:6771521 |
| Seligmann B and Gallin JI | Secretagogue modulation of the response of human neutrophils to chemoattractants: studies with a membrane potential sensitive cyanine dye. | 1980 | Mol. Immunol. | pmid:6771522 |
| Sato M et al. | Two distinct Fc gamma Rs on guinea-pig polymorphonuclear leukocytes differ from each other in their eliciting activities for O2- generation. | 1988 | Mol. Immunol. | pmid:2967427 |
| Horváth LI et al. | Changes in the lateral ordering of the macrophage plasma membrane during Fc receptor mediated phagocytosis. | 1982 | Mol. Immunol. | pmid:7162518 |
| Leslie RG | Macrophage handling of soluble immune complexes: evaluation of mechanisms involved in the selective clearance of complexes from the circulation. | 1985 | Mol. Immunol. | pmid:3927153 |
| Gagnerault MC et al. | Two different mechanisms for the inhibition of rosette formation in mice. | 1995 | Mol. Immunol. | pmid:7898494 |
| Cremaschi G et al. | Colchicine blocks beta adrenoceptor and class I antigen-specific interactions. | 1989 | Mol. Immunol. | pmid:2550817 |
| Koukouritaki SB et al. | Tyrosine phosphorylation of focal adhesion kinase and paxillin regulates the signaling mechanism of the rapid nongenomic action of dexamethasone on actin cytoskeleton. | 1999 | Mol. Med. | pmid:10656875 |
| Riley LW et al. | HeLa cell invasion by a strain of enteropathogenic Escherichia coli that lacks the O-antigenic polysaccharide. | 1990 | Mol. Microbiol. | pmid:1706454 |
| Zenewicz LA et al. | Listeria monocytogenes virulence proteins induce surface expression of Fas ligand on T lymphocytes. | 2004 | Mol. Microbiol. | pmid:14982640 |
| Plácido AI et al. | Phosphatase 2A Inhibition Affects Endoplasmic Reticulum and Mitochondria Homeostasis Via Cytoskeletal Alterations in Brain Endothelial Cells. | 2017 | Mol. Neurobiol. | pmid:26732598 |
| GarcÃa-Krauss A et al. | Dehydroascorbic Acid Promotes Cell Death in Neurons Under Oxidative Stress: a Protective Role for Astrocytes. | 2016 | Mol. Neurobiol. | pmid:26497038 |
| Isobe H et al. | Nonviral gene delivery by tetraamino fullerene. | 2006 Mar-Apr | Mol. Pharm. | pmid:16579641 |
| Joost HG et al. | Activation of adenylate cyclase and inhibition of glucose transport in rat adipocytes by forskolin analogues: structural determinants for distinct sites of action. | 1988 | Mol. Pharmacol. | pmid:3357486 |
| Hellwig B and Joost HG | Differentiation of erythrocyte-(GLUT1), liver-(GLUT2), and adipocyte-type (GLUT4) glucose transporters by binding of the inhibitory ligands cytochalasin B, forskolin, dipyridamole, and isobutylmethylxanthine. | 1991 | Mol. Pharmacol. | pmid:1716731 |
| Chao JI and Liu HF | The blockage of survivin and securin expression increases the cytochalasin B-induced cell death and growth inhibition in human cancer cells. | 2006 | Mol. Pharmacol. | pmid:16219911 |
| Mollinedo F et al. | Cytoplasmic microtubules in human neutrophil degranulation: reversible inhibition by the colchicine analogue 2-methoxy-5-(2',3',4'-trimethoxyphenyl)-2,4,6-cycloheptatrien-1- one. | 1989 | Mol. Pharmacol. | pmid:2682203 |
| Kang KW et al. | Phosphatidylinositol 3-kinase regulates nuclear translocation of NF-E2-related factor 2 through actin rearrangement in response to oxidative stress. | 2002 | Mol. Pharmacol. | pmid:12391262 |
| Heasley LE et al. | Export of cyclic AMP from avian red cells. Independence from major membrane transporters and specific inhibition by prostaglandin A. | 1985 | Mol. Pharmacol. | pmid:2981402 |
| Joost HG and Steinfelder HJ | Forskolin inhibits insulin-stimulated glucose transport in rat adipose cells by a direct interaction with the glucose transporter. | 1987 | Mol. Pharmacol. | pmid:3470598 |
| Bradford PG and Rubin RP | Characterization of formylmethionyl-leucyl-phenylalanine stimulation of inositol trisphosphate accumulation in rabbit neutrophils. | 1985 | Mol. Pharmacol. | pmid:2981403 |
| Presicce GA and Yang X | Parthenogenetic development of bovine oocytes matured in vitro for 24 hr and activated by ethanol and cycloheximide. | 1994 | Mol. Reprod. Dev. | pmid:7980946 |
| Shaha C | Antibody-induced changes on rabbit sperm surface inhibit gamete interaction. | 1994 | Mol. Reprod. Dev. | pmid:7980948 |
| Li GP et al. | Rabbit cloning: improved fusion rates using cytochalasin B in the fusion buffer. | 2002 | Mol. Reprod. Dev. | pmid:11803553 |
| Paradis F et al. | RNA interference as a tool to study gene function in bovine oocytes. | 2005 | Mol. Reprod. Dev. | pmid:15570624 |
| Van Stekelenburg-Hamers AE et al. | Nuclear transfer and electrofusion in bovine in vitro-matured/in vitro-fertilized embryos: effect of media and electrical fusion parameters. | 1993 | Mol. Reprod. Dev. | pmid:8286111 |
| Pinto-Correia C et al. | Chromatin and microtubule organization in the first cell cycle in rabbit parthenotes and nuclear transplant embryos. | 1993 | Mol. Reprod. Dev. | pmid:8418814 |
| Lee JW et al. | Optimization of parthenogenetic activation protocol in porcine. | 2004 | Mol. Reprod. Dev. | pmid:15039947 |
| Amikura RM et al. | Cyclic appearance of cytoplasmic NOR-silver-stained particles in sea urchin embryos. | 1991 | Mol. Reprod. Dev. | pmid:1718332 |
| Miao Y et al. | Fate of the first polar bodies in mouse oocytes. | 2004 | Mol. Reprod. Dev. | pmid:15278906 |
| Rho GJ et al. | Microtubulin configuration and mitochondrial distribution after ultra-rapid cooling of bovine oocytes. | 2002 | Mol. Reprod. Dev. | pmid:12412049 |
| Chow RL and Elinson RP | Local alteration of cortical actin in Xenopus eggs by the fertilizing sperm. | 1993 | Mol. Reprod. Dev. | pmid:8507483 |
| DiMaggio AJ et al. | Cortical granule exocytosis in hamster eggs requires microfilaments. | 1997 | Mol. Reprod. Dev. | pmid:9170113 |
| Fukui Y et al. | Parthenogenetic development of bovine oocytes treated with ethanol and cytochalasin B after in vitro maturation. | 1992 | Mol. Reprod. Dev. | pmid:1449802 |
| Popova E et al. | Efficient production of nuclear transferred rat embryos by modified methods of reconstruction. | 2009 | Mol. Reprod. Dev. | pmid:18543283 |
| Song K et al. | Post-activation treatment with demecolcine improves development of somatic cell nuclear transfer embryos in pigs by modifying the remodeling of donor nuclei. | 2009 | Mol. Reprod. Dev. | pmid:19107916 |
| Sutovský P et al. | F-actin is involved in control of bovine cumulus expansion. | 1995 | Mol. Reprod. Dev. | pmid:7576620 |
| Lam SH et al. | Chemical Constituents from the Stems of Tinospora sinensis and Their Bioactivity. | 2018 | Molecules | pmid:30301176 |
| Huang HL et al. | Actin-containing microprocesses in the fusion of cultured chick myoblasts. | 1978 May-Jun | Muscle Nerve | pmid:375087 |
| Matsushima T et al. | Validation study of the in vitro micronucleus test in a Chinese hamster lung cell line (CHL/IU). | 1999 | Mutagenesis | pmid:10567032 |
| Fenech M et al. | Necrosis, apoptosis, cytostasis and DNA damage in human lymphocytes measured simultaneously within the cytokinesis-block micronucleus assay: description of the method and results for hydrogen peroxide. | 1999 | Mutagenesis | pmid:10567036 |
| Snyder RD and Diehl MS | The bleomycin amplification assay in V79 cells predicts frameshift mutagenicity of intercalative agents. | 2000 | Mutagenesis | pmid:10792011 |
| Doepker CL et al. | Lack of induction of micronuclei in human peripheral blood lymphocytes treated with hydroquinone. | 2000 | Mutagenesis | pmid:11076999 |
| Maffei F et al. | Increased cytogenetic damage detected by FISH analysis on micronuclei in peripheral lymphocytes from alcoholics. | 2000 | Mutagenesis | pmid:11077004 |
| Falck GC et al. | Nature of anaphase laggards and micronuclei in female cytokinesis-blocked lymphocytes. | 2002 | Mutagenesis | pmid:11880539 |
| Wojda A et al. | Effects of age and gender on micronucleus and chromosome nondisjunction frequencies in centenarians and younger subjects. | 2007 | Mutagenesis | pmid:17284771 |
| Schultz N and Onfelt A | Video time-lapse study of mitosis in binucleate V79 cells: chromosome segregation and cleavage. | 1994 | Mutagenesis | pmid:8201944 |
| Leopardi P et al. | Influence of donor age on vinblastine-induced chromosome malsegregation in cultured peripheral lymphocytes. | 2002 | Mutagenesis | pmid:11752239 |
| Crott J and Fenech M | Preliminary study of the genotoxic potential of homocysteine in human lymphocytes in vitro. | 2001 | Mutagenesis | pmid:11320146 |
| Tsai MH et al. | Dynamics of changes in micronucleus frequencies in subjects post cessation of chronic low-dose radiation exposure. | 2001 | Mutagenesis | pmid:11320151 |
| Champion AR et al. | The micronucleus assay: an evaluation of its use in determining radiosensitivity in vitro. | 1995 | Mutagenesis | pmid:7666771 |
| Ellard S and Parry EM | A modified protocol for the cytochalasin B in vitro micronucleus assay using whole human blood or separated lymphocyte cultures. | 1993 | Mutagenesis | pmid:8377650 |
| Crofton-Sleigh C et al. | Micronucleus assays using cytochalasin-blocked MCL-5 cells, a proprietary human cell line expressing five human cytochromes P-450 and microsomal epoxide hydrolase. | 1993 | Mutagenesis | pmid:8377657 |
| de Stoppelaar JM et al. | In vivo cytokinesis blocked micronucleus assay with carbendazim in rat fibroblasts and comparison with in vitro assays. | 2000 | Mutagenesis | pmid:10719042 |
| Balajee AS et al. | Multicolour FISH analysis of ionising radiation induced micronucleus formation in human lymphocytes. | 2014 | Mutagenesis | pmid:25217771 |
| Castelain P et al. | Automated detection of cytochalasin-B blocked binucleated lymphocytes for scoring micronuclei. | 1993 | Mutagenesis | pmid:7690875 |
| Varga D et al. | An automated scoring procedure for the micronucleus test by image analysis. | 2004 | Mutagenesis | pmid:15388812 |
| Cakmak Demircigil G et al. | Micronucleus frequencies in peripheral blood lymphocytes of children with chronic kidney disease. | 2011 | Mutagenesis | pmid:21669938 |
| Lee TK et al. | Assessment of two protocols for the human lymphocyte cytokinesis-blocked micronucleus assay. | 1995 | Mutagenesis | pmid:7476276 |
| Burgaz S et al. | Micronucleus frequencies in lymphocytes and buccal epithelial cells from patients having head and neck cancer and their first-degree relatives. | 2011 | Mutagenesis | pmid:21248276 |
| Minissi S et al. | Effect of cytochalasin B on the induction of chromosome missegregation by colchicine at low concentrations in human lymphocytes. | 1999 | Mutagenesis | pmid:10474820 |
| Kirsch-Volders M et al. | Mitotic non-disjunction as a mechanism for in vitro aneuploidy induction by X-rays in primary human cells. | 1996 | Mutagenesis | pmid:8671754 |
| Zijno A et al. | Simultaneous detection of X-chromosome loss and non-disjunction in cytokinesis-blocked human lymphocytes by in situ hybridization with a centromeric DNA probe; implications for the human lymphocyte in vitro micronucleus assay using cytochalasin B. | 1994 | Mutagenesis | pmid:7934962 |
| Guccini S et al. | Effects of spindle poisons in peripheral human lymphocytes by the in vitro cytokinesis-block micronucleus assay. | 2012 | Mutagenesis | pmid:22952150 |
| Touil N et al. | Analysis of chromosome loss and chromosome segregation in cytokinesis-blocked human lymphocytes: non-disjunction is the prevalent mistake in chromosome segregation produced by low dose exposure to ionizing radiation. | 2000 | Mutagenesis | pmid:10640524 |
| Oliveira NG et al. | Assessment of the adaptive response induced by quercetin using the MNCB peripheral blood human lymphocytes assay. | 2000 | Mutagenesis | pmid:10640534 |
| Arsoy NS et al. | Micronuclei in peripheral blood from patients after cytostatic therapy mainly arise ex vivo from persistent damage. | 2009 | Mutagenesis | pmid:19423564 |
| Heddle JA et al. | Concurrent detection of gene mutations and chromosomal aberrations induced in vivo in somatic cells. | 1990 | Mutagenesis | pmid:2188072 |
| Surrallés J et al. | The effect of cytochalasin-B concentration on the frequency of micronuclei induced by four standard mutagens. Results from two laboratories. | 1994 | Mutagenesis | pmid:7968577 |
| Littlefield LG et al. | Comparisons of dose-response parameters for radiation-induced acentric fragments and micronuclei observed in cytokinesis-arrested lymphocytes. | 1989 | Mutagenesis | pmid:2674605 |
| Minissi S et al. | Direct and indirect non-disjunction in the origin of trisomy in cultured human lymphocytes. | 1999 | Mutagenesis | pmid:10567030 |
| Cimini D et al. | Differences in malsegregation rates obtained by scoring ana-telophases or binucleate cells. | 1999 | Mutagenesis | pmid:10567031 |