CYTOCHALASIN B is a lipid of Polyketides (PK) class. Cytochalasin b is associated with abnormalities such as Renal tubular disorder and Chagas Disease. The involved functions are known as Membrane Protein Traffic, inhibitors, Metabolic Inhibition, Biochemical Pathway and Increased Sensitivy. Cytochalasin b often locates in Cytoplasmic matrix, Plasma membrane, Microtubules, Extracellular and Protoplasm. The associated genes with CYTOCHALASIN B are SLC2A2 gene, PFDN5 gene, SLC2A1 gene, OMG gene and SPEN gene. The related lipids are Steroids, Lipopolysaccharides and Liposomes. The related experimental models are Xenograft Model.
To understand associated biological information of CYTOCHALASIN B, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
CYTOCHALASIN B is suspected in Renal tubular disorder, Chagas Disease and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with CYTOCHALASIN B
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Xenograft Model are used in the study 'Endofacial competitive inhibition of the glucose transporter 1 activity by gossypol.' (Pérez A et al., 2009).
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Authors | Title | Published | Journal | PubMed Link |
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Connolly TJ et al. | Effects of bilayer cholesterol on human erythrocyte hexose transport protein activity in synthetic lecithin bilayers. | 1985 | Biochemistry | pmid:4040391 |
Baldwin SA et al. | Monosaccharide transporter of the human erythrocyte. Characterization of an improved preparation. | 1982 | Biochemistry | pmid:6890381 |
Tsukamoto T et al. | Adenosine cyclic 3',5'-monophosphate uptake and regulation of membrane protein kinase in intact human erythrocytes. | 1980 | Biochemistry | pmid:6243958 |
Cloherty EK et al. | The red blood cell glucose transporter presents multiple, nucleotide-sensitive sugar exit sites. | 2001 | Biochemistry | pmid:11747430 |
Carruthers A and Melchior DL | Human erythrocyte hexose transporter activity is governed by bilayer lipid composition in reconstituted vesicles. | 1984 | Biochemistry | pmid:6543323 |
May JM et al. | Tryptic digestion of the human erythrocyte glucose transporter: effects on ligand binding and tryptophan fluorescence. | 1993 | Biochemistry | pmid:8373759 |
Heard KS et al. | ATP-dependent substrate occlusion by the human erythrocyte sugar transporter. | 2000 | Biochemistry | pmid:10715121 |
May JM and Beechem JM | Monitoring conformational change in the human erythrocyte glucose carrier: use of a fluorescent probe attached to an exofacial carrier sulfhydryl. | 1993 | Biochemistry | pmid:8457556 |
Gorga FR and Lienhard GE | Equilibria and kinetics of ligand binding to the human erythrocyte glucose transporter. Evidence for an alternating conformation model for transport. | 1981 | Biochemistry | pmid:7295669 |
Axelrod JD and Pilch PF | Unique cytochalasin B binding characteristics of the hepatic glucose carrier. | 1983 | Biochemistry | pmid:6683102 |
Shanahan MF | Characterization of cytochalasin B photoincorporation into human erythrocyte D-glucose transporter and F-actin. | 1983 | Biochemistry | pmid:6683567 |
Tai PK and Carter-Su C | Monoclonal antibody to the human glucose transporter that differentiates between the glucose and nucleoside transporters. | 1988 | Biochemistry | pmid:3191107 |
Bloch R | Inhibition of glucose transport in the human erythrocyte by cytochalasin B. | 1973 | Biochemistry | pmid:4773858 |
Epand RF et al. | Glucose-induced thermal stabilization of the native conformation of GLUT 1. | 1999 | Biochemistry | pmid:9890928 |
Reyes AM et al. | Nicotinamide is not a substrate of the facilitative hexose transporter GLUT1. | 2002 | Biochemistry | pmid:12069599 |
Rampal AL et al. | Structure of cytochalasins and cytochalasin B binding sites in human erythrocyte membranes. | 1980 | Biochemistry | pmid:7356953 |
Lachaal M et al. | Cadmium increases GLUT1 substrate binding affinity in vitro while reducing its cytochalasin B binding affinity. | 1996 | Biochemistry | pmid:8942661 |
Himmelreich U et al. | 13C NMR studies of vitamin C transport and its redox cycling in human erythrocytes. | 1998 | Biochemistry | pmid:9585573 |
Robichaud T et al. | Determinants of ligand binding affinity and cooperativity at the GLUT1 endofacial site. | 2011 | Biochemistry | pmid:21384913 |
Brekkan E et al. | Immobilized membrane vesicle or proteoliposome affinity chromatography. Frontal analysis of interactions of cytochalasin B and D-glucose with the human red cell glucose transporter. | 1996 | Biochemistry | pmid:8810921 |
May JM et al. | Localization of a reactive exofacial sulfhydryl on the glucose carrier of human erythrocytes. | 1990 | Biochemistry | pmid:2261480 |
Sampath P and Pollard TD | Effects of cytochalasin, phalloidin, and pH on the elongation of actin filaments. | 1991 | Biochemistry | pmid:1899622 |
Lienhard GE et al. | Monosaccharide transport system of the human erythrocyte. Identification of the cytochalasin B binding component. | 1977 | Biochemistry | pmid:911802 |
Sogin DC and Hinkle PC | Binding of cytochalasin B to human erythrocyte glucose transporter. | 1980 | Biochemistry | pmid:7192569 |
Carruthers A | Anomalous asymmetric kinetics of human red cell hexose transfer: role of cytosolic adenosine 5'-triphosphate. | 1986 | Biochemistry | pmid:3718945 |
Anichini E et al. | Interaction of urokinase-type plasminogen activator with its receptor rapidly induces activation of glucose transporters. | 1997 | Biochemistry | pmid:9115983 |
Yang Q and Lundahl P | Immobilized proteoliposome affinity chromatography for quantitative analysis of specific interactions between solutes and membrane proteins. Interaction of cytochalasin B and D-glucose with the glucose transporter Glut1. | 1995 | Biochemistry | pmid:7779771 |
Scarlata S et al. | Effect of lipid packing on the conformational states of purified GLUT-1 hexose transporter. | 1995 | Biochemistry | pmid:7779817 |
Hamill S et al. | The human erythrocyte sugar transporter presents two sugar import sites. | 1999 | Biochemistry | pmid:10606533 |
Kasahara T and Kasahara M | Characterization of rat Glut4 glucose transporter expressed in the yeast Saccharomyces cerevisiae: comparison with Glut1 glucose transporter. | 1997 | Biochim. Biophys. Acta | pmid:9059504 |
Deziel M et al. | Labelling of the human erythrocyte glucose transporter with 3H-labelled cytochalasin B occurs via protein photoactivation. | 1984 | Biochim. Biophys. Acta | pmid:6539126 |
Shefcyk J et al. | Phloretin is a potent inhibitor of rabbit neutrophil activation by chemotactic factors. | 1983 | Biochim. Biophys. Acta | pmid:6830775 |
Jhun BH et al. | Glucose and nucleoside transporters of human erythrocytes: effects of detergents on immunoadsorption of a membrane protein to its monoclonal antibody. | 1991 | Biochim. Biophys. Acta | pmid:1705438 |
Plagemann PG and Woffendin C | Comparison of the equilibrium exchange of nucleosides and 3-O-methylglucose in human erythrocytes and of the effects of cytochalasin B, phloretin and dipyridamole on their transport. | 1987 | Biochim. Biophys. Acta | pmid:3580369 |
Kitagawa K | Ca2+-dependent translocation of hexose carrier in mouse fibroblast Swiss 3T3 cells. | 1987 | Biochim. Biophys. Acta | pmid:3105598 |
George TP et al. | Inhibition of phosphatidylcholine and phosphatidylethanolamine biosynthesis by cytochalasin B in cultured glioma cells: potential regulation of biosynthesis by Ca(2+)-dependent mechanisms. | 1991 | Biochim. Biophys. Acta | pmid:1854804 |
Wardzala LJ and Jeanrenaud B | Identification of the D-glucose-inhibitable cytochalasin B binding site as the glucose transporter in rat diaphragm plasma and microsomal membranes. | 1983 | Biochim. Biophys. Acta | pmid:6338925 |
Cremaschi D et al. | Endocytosis inhibitors abolish the active transport of polypeptides in the mucosa of the nasal upper concha of the rabbit. | 1996 | Biochim. Biophys. Acta | pmid:8634313 |
Glick JM and Rothblat GH | Effects of metabolic inhibitors on the synthesis and release of lipoprotein lipase in cultured cells derived from the stromal-vascular fraction of rat adipose tissue. | 1980 | Biochim. Biophys. Acta | pmid:7378429 |
Smolen JE et al. | The roles of extracellular and intracellular calcium in lysosomal enzyme release and superoxide anion generation by human neutrophils. | 1981 | Biochim. Biophys. Acta | pmid:6271257 |
Rosenthal KS et al. | Herpes simplex virus type 1 penetration initiates mobilization of cell surface proteins. | 1988 | Biochim. Biophys. Acta | pmid:2838084 |
Kimura Y et al. | Effects of baicalein on leukotriene biosynthesis and degranulation in human polymorphonuclear leukocytes. | 1987 | Biochim. Biophys. Acta | pmid:2825795 |
Holman GD et al. | Photolabeling of erythrocyte and adipocyte hexose transporters using a benzophenone derivative of bis(D-mannose). | 1988 | Biochim. Biophys. Acta | pmid:3207733 |
Vénien C and Le Grimellec C | The involvement of cytoskeletal proteins in the maintenance of phospholipid topology in renal brush-border membranes. | 1988 | Biochim. Biophys. Acta | pmid:3207748 |
Jessen F and Hoffmann EK | Activation of the Na+/K+/Cl- cotransport system by reorganization of the actin filaments in Ehrlich ascites tumor cells. | 1992 | Biochim. Biophys. Acta | pmid:1390848 |
Miller JH et al. | Polarity of transport of 2-deoxy-D-glucose and D-glucose by cultured renal epithelia (LLC-PK1). | 1992 | Biochim. Biophys. Acta | pmid:1390850 |
Ko HH et al. | Chemistry and biological activities of constituents from Morus australis. | 1999 | Biochim. Biophys. Acta | pmid:10434047 |
Dancker P and Fischer S | The influence of adenosine triphosphate, adenosine diphosphate and cytochalasin B on nucleotide exchange of F-actin. Evidence that treadmilling is not involved. | 1985 | Biochim. Biophys. Acta | pmid:3967046 |
Bakker-Grunwald T et al. | Effects of cytochalasin B on Na+ content and cell volume of Entamoeba histolytica. | 1985 | Biochim. Biophys. Acta | pmid:2859891 |
Dijkstra J et al. | Effects of (dihydro)cytochalasin B, colchicine, monensin and trifluoperazine on uptake and processing of liposomes by Kupffer cells in culture. | 1985 | Biochim. Biophys. Acta | pmid:3978127 |