CYTOCHALASIN B

CYTOCHALASIN B is a lipid of Polyketides (PK) class. Cytochalasin b is associated with abnormalities such as Renal tubular disorder and Chagas Disease. The involved functions are known as Membrane Protein Traffic, inhibitors, Metabolic Inhibition, Biochemical Pathway and Increased Sensitivy. Cytochalasin b often locates in Cytoplasmic matrix, Plasma membrane, Microtubules, Extracellular and Protoplasm. The associated genes with CYTOCHALASIN B are SLC2A2 gene, PFDN5 gene, SLC2A1 gene, OMG gene and SPEN gene. The related lipids are Steroids, Lipopolysaccharides and Liposomes. The related experimental models are Xenograft Model.

Cross Reference

Introduction

To understand associated biological information of CYTOCHALASIN B, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with CYTOCHALASIN B?

CYTOCHALASIN B is suspected in Renal tubular disorder, Chagas Disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with CYTOCHALASIN B

MeSH term MeSH ID Detail
Thrombocytopenia D013921 15 associated lipids
Starvation D013217 47 associated lipids
Pituitary Neoplasms D010911 4 associated lipids
Pharyngeal Neoplasms D010610 4 associated lipids
Aggressive Periodontitis D010520 8 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Neutropenia D009503 15 associated lipids
Melanoma D008545 69 associated lipids
Medulloblastoma D008527 22 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Lymphoproliferative Disorders D008232 7 associated lipids
Lymphoma D008223 18 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Lung Neoplasms D008175 171 associated lipids
Leukemia, Myeloid D007951 52 associated lipids
Leukemia, Lymphoid D007945 18 associated lipids
Leukemia, Experimental D007942 42 associated lipids
Leukemia D007938 74 associated lipids
Kidney Diseases D007674 29 associated lipids
Adenoma, Islet Cell D007516 7 associated lipids
Per page 10 20 50 100 | Total 79

PubChem Associated disorders and diseases

What pathways are associated with CYTOCHALASIN B

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with CYTOCHALASIN B?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with CYTOCHALASIN B?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with CYTOCHALASIN B?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with CYTOCHALASIN B?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with CYTOCHALASIN B?

Xenograft Model

Xenograft Model are used in the study 'Endofacial competitive inhibition of the glucose transporter 1 activity by gossypol.' (Pérez A et al., 2009).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with CYTOCHALASIN B

Download all related citations
Per page 10 20 50 100 | Total 4982
Authors Title Published Journal PubMed Link
Coderre PE et al. Rapid substrate translocation by the multisubunit, erythroid glucose transporter requires subunit associations but not cooperative ligand binding. 1995 Biochemistry pmid:7626647
Mrotek JJ and Hall PF Response of adrenal tumor cells to adrenocorticotropin: site of inhibition by cytochalasin B. 1977 Biochemistry pmid:196628
Baldwin SA et al. Monosaccharide transporter of the human erythrocyte. Characterization of an improved preparation. 1982 Biochemistry pmid:6890381
Cloherty EK et al. The red blood cell glucose transporter presents multiple, nucleotide-sensitive sugar exit sites. 2001 Biochemistry pmid:11747430
Burant CF and Bell GI Mammalian facilitative glucose transporters: evidence for similar substrate recognition sites in functionally monomeric proteins. 1992 Biochemistry pmid:1420159
Hayden SM et al. Analysis of the interactions of actin depolymerizing factor with G- and F-actin. 1993 Biochemistry pmid:8399168
Heard KS et al. ATP-dependent substrate occlusion by the human erythrocyte sugar transporter. 2000 Biochemistry pmid:10715121
King AP et al. Cytochalasin B interferes with conformational changes of the human erythrocyte glucose transporter induced by internal and external sugar binding. 1991 Biochemistry pmid:1747373
Hebert DN and Carruthers A Cholate-solubilized erythrocyte glucose transporters exist as a mixture of homodimers and homotetramers. 1991 Biochemistry pmid:2029513
Hah JS et al. Effects of physical states of phospholipids on the incorporation and cytochalasin B binding activity of human erythrocyte membrane proteins in reconstituted vesicles. 1983 Biochemistry pmid:6626531
Bloch R Inhibition of glucose transport in the human erythrocyte by cytochalasin B. 1973 Biochemistry pmid:4773858
Carruthers A and Helgerson AL Inhibitions of sugar transport produced by ligands binding at opposite sides of the membrane. Evidence for simultaneous occupation of the carrier by maltose and cytochalasin B. 1991 Biochemistry pmid:2018762
Epand RF et al. Glucose-induced thermal stabilization of the native conformation of GLUT 1. 1999 Biochemistry pmid:9890928
Rampal AL et al. Structure of cytochalasins and cytochalasin B binding sites in human erythrocyte membranes. 1980 Biochemistry pmid:7356953
Carter-Su C et al. Reconstituted D-glucose transport from the adipocyte plasma membrane. Chromatographic resolution of transport activity from membrane glycoproteins using immobilized concanavalin A. 1980 Biochemistry pmid:7387979
Freer RJ et al. Further studies on the structural requirements for synthetic peptide chemoattractants. 1980 Biochemistry pmid:7387981
Lachaal M et al. Cadmium increases GLUT1 substrate binding affinity in vitro while reducing its cytochalasin B binding affinity. 1996 Biochemistry pmid:8942661
Himmelreich U et al. 13C NMR studies of vitamin C transport and its redox cycling in human erythrocytes. 1998 Biochemistry pmid:9585573
Robichaud T et al. Determinants of ligand binding affinity and cooperativity at the GLUT1 endofacial site. 2011 Biochemistry pmid:21384913
Brekkan E et al. Immobilized membrane vesicle or proteoliposome affinity chromatography. Frontal analysis of interactions of cytochalasin B and D-glucose with the human red cell glucose transporter. 1996 Biochemistry pmid:8810921
Lienhard GE et al. Monosaccharide transport system of the human erythrocyte. Identification of the cytochalasin B binding component. 1977 Biochemistry pmid:911802
Sogin DC and Hinkle PC Binding of cytochalasin B to human erythrocyte glucose transporter. 1980 Biochemistry pmid:7192569
Carruthers A Anomalous asymmetric kinetics of human red cell hexose transfer: role of cytosolic adenosine 5'-triphosphate. 1986 Biochemistry pmid:3718945
Katzen HM et al. Evidence that the insulin-like activities of concanavalin A and insulin are mediated by a common insulin receptor linked effector system. 1981 Biochemistry pmid:7028110
Anichini E et al. Interaction of urokinase-type plasminogen activator with its receptor rapidly induces activation of glucose transporters. 1997 Biochemistry pmid:9115983
Yang Q and Lundahl P Immobilized proteoliposome affinity chromatography for quantitative analysis of specific interactions between solutes and membrane proteins. Interaction of cytochalasin B and D-glucose with the glucose transporter Glut1. 1995 Biochemistry pmid:7779771
Scarlata S et al. Effect of lipid packing on the conformational states of purified GLUT-1 hexose transporter. 1995 Biochemistry pmid:7779817
Hamill S et al. The human erythrocyte sugar transporter presents two sugar import sites. 1999 Biochemistry pmid:10606533
Gorga FR and Lienhard GE Changes in the intrinsic fluorescence of the human erythrocyte monosaccharide transporter upon ligand binding. 1982 Biochemistry pmid:7200802
Meier DA and Garner CW Glucose transport by uterine plasma membranes. 1985 Biochim. Biophys. Acta pmid:4038886
Speizer L et al. Asymmetric transport of a fluorescent glucose analogue by human erythrocytes. 1985 Biochim. Biophys. Acta pmid:4039191
Hu XJ et al. The abnormality of glucose transporter in the erythrocyte membrane of Chinese type 2 diabetic patients. 2000 Biochim. Biophys. Acta pmid:10825451
May JM Differential labeling of the erythrocyte hexose carrier by N-ethylmaleimide: correlation of transport inhibition with reactive carrier sulfhydryl groups. 1989 Biochim. Biophys. Acta pmid:2590670
Bihler I et al. Monensin stimulates sugar transport in avian erythrocytes. 1985 Biochim. Biophys. Acta pmid:4063360
Kitagawa K et al. Effect of tunicamycin on hexose transport in mouse embryo fibroblast Swiss 3T3 cells. 1985 Biochim. Biophys. Acta pmid:4063363
Johnson G et al. The effects of cytoskeletal inhibitors on intestinal iron absorption in the rat. 1985 Biochim. Biophys. Acta pmid:4063390
Pratten MK and Lloyd JB Pinocytosis and phagocytosis: the effect of size of a particulate substrate on its mode of capture by rat peritoneal macrophages cultured in vitro. 1986 Biochim. Biophys. Acta pmid:3008849
Yeh CK and Rodan GA Microtubule disruption enhances prostaglandin E2 production in osteoblastic cells. 1987 Biochim. Biophys. Acta pmid:2880609
Bigornia L and Bihler I 3-O-methyl-D-glucose uptake in isolated bovine adrenal chromaffin cells. 1986 Biochim. Biophys. Acta pmid:3511975
Holman GD and Rees WD Photolabelling of the hexose transporter at external and internal sites: fragmentation patterns and evidence for a conformational change. 1987 Biochim. Biophys. Acta pmid:3545294
Löw I and Dancker P Effect of cytochalasin B on formation and properties of muscle F-actin. 1976 Biochim. Biophys. Acta pmid:132190
Audhya TK and Gibson KD Effects of medium composition and metabolic inhibitors on glycosaminoglycan synthesis in chick embryo cartilage and its stimulation by serum and triiodothyronine. 1976 Biochim. Biophys. Acta pmid:133721
Czech MP et al. Phlorizin--receptor interactions in fat cell plasma membranes. 1973 Biochim. Biophys. Acta pmid:4761095
Brot-Laroche E et al. Characterization of the D-glucose/Na+ cotransport system in the intestinal brush-border membrane by using the specific substrate, methyl alpha-D-glucopyranoside. 1987 Biochim. Biophys. Acta pmid:3663668
Dahlgren C et al. Activation of the oxygen-radical-generating system in granules of intact human neutrophils by a calcium ionophore (ionomycin). 1992 Biochim. Biophys. Acta pmid:1329978
Franklin CC et al. Insulin regulation of glucose metabolism in HT29 colonic adenocarcinoma cells: activation of glycolysis without augmentation of glucose transport. 1988 Biochim. Biophys. Acta pmid:3052595
Goldstein BJ and Livingston JN Effects in adipocytes of diamide on GSH levels, glucose uptake and cell integrity. 1978 Biochim. Biophys. Acta pmid:718890
Cairns MT et al. Investigation of the structure and function of the human erythrocyte glucose transporter by proteolytic dissection. 1987 Biochim. Biophys. Acta pmid:3689782
Diez de los Rios A et al. Cytochalasin B does not stimulate sugar uptake into small intestine of necturus or chick. 1980 Biochim. Biophys. Acta pmid:7448186
Wendel H and Dancker P Kinetics of actin depolymerization: influence of ions, temperature, age of F-actin, cytochalasin B and phalloidin. 1986 Biochim. Biophys. Acta pmid:3756187