CYTOCHALASIN B is a lipid of Polyketides (PK) class. Cytochalasin b is associated with abnormalities such as Renal tubular disorder and Chagas Disease. The involved functions are known as Membrane Protein Traffic, inhibitors, Metabolic Inhibition, Biochemical Pathway and Increased Sensitivy. Cytochalasin b often locates in Cytoplasmic matrix, Plasma membrane, Microtubules, Extracellular and Protoplasm. The associated genes with CYTOCHALASIN B are SLC2A2 gene, PFDN5 gene, SLC2A1 gene, OMG gene and SPEN gene. The related lipids are Steroids, Lipopolysaccharides and Liposomes. The related experimental models are Xenograft Model.
To understand associated biological information of CYTOCHALASIN B, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
CYTOCHALASIN B is suspected in Renal tubular disorder, Chagas Disease and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with CYTOCHALASIN B
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Xenograft Model are used in the study 'Endofacial competitive inhibition of the glucose transporter 1 activity by gossypol.' (Pérez A et al., 2009).
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Authors | Title | Published | Journal | PubMed Link |
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Michelakakis H and Danpure CJ | The effect of cytochalasin B on the release of lysosomal enzymes and intra-lysosomally-stored polyvinylpyrrolidone in the isolated perfused rat liver. | 1984 | Biochem. Pharmacol. | pmid:6430298 |
Elferink JG | Chlorpromazine inhibits phagocytosis and exocytosis in rabbit polymorphonuclear leukocytes. | 1979 | Biochem. Pharmacol. | pmid:375938 |
Tsuruo T and Iida H | Effects of cytochalasins and colchicine on the accumulation and retention of daunomycin and vincristine in drug resistant tumor cells. | 1986 | Biochem. Pharmacol. | pmid:3457567 |
Skidgel RA et al. | Metabolism of substance P and bradykinin by human neutrophils. | 1991 | Biochem. Pharmacol. | pmid:1708255 |
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Theodoropoulos PA et al. | Cytochalasin B may shorten actin filaments by a mechanism independent of barbed end capping. | 1994 | Biochem. Pharmacol. | pmid:8204105 |
Smith RJ et al. | Stimulation of the human neutrophil superoxide anion-generating system with 1-O-hexadecyl/octadecyl-2-acetyl-sn-glyceryl-3- phosphorylcholine. | 1984 | Biochem. Pharmacol. | pmid:6324816 |
Dayer JM et al. | Effects of prostaglandin E2, indomethacin, trifluoperazine and drugs affecting the cytoskeleton on collagenase production by cultured adherent rheumatoid synovial cells. | 1984 | Biochem. Pharmacol. | pmid:6089839 |
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Michelakakis H and Danpure CJ | The release of intralysosomally-stored 125I-Triton WR-1339 and lysosomal enzymes from the isolated perfused rat liver in the presence and absence of cytochalasin B. | 1986 | Biochem. Pharmacol. | pmid:3082335 |
Soares-da-Silva P | Actin cytoskeleton, tubular sodium and the renal synthesis of dopamine. | 1992 | Biochem. Pharmacol. | pmid:1449540 |
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Lucas M and Solano F | Opposite effect of cytochalasin B on agonist-induced respiratory burst in neutrophils and monocytes. | 1991 | Biochem. Pharmacol. | pmid:1859454 |
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Smith RJ | Phagocytic release of lysosomal enzymes from guinea pig neutrophils--regulation by corticosteroids, autonomic neurohormones and cyclic nucleotides. | 1977 | Biochem. Pharmacol. | pmid:21664 |
Stournaras C et al. | Altered actin polymerization dynamics in various malignant cell types: evidence for differential sensitivity to cytochalasin B. | 1996 | Biochem. Pharmacol. | pmid:8937443 |
Morita K et al. | Effects of cytoskeleton-disrupting drugs on ouabain-stimulated catecholamine secretion from cultured adrenal chromaffin cells. | 1988 | Biochem. Pharmacol. | pmid:3401261 |
Michelakakis H and Danpure CJ | The effect of cytochalasin B on the release of lysosomal enzymes from isolated rat hepatocytes [proceedings]. | 1979 | Biochem. Soc. Trans. | pmid:119657 |
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Michelakakis H and Danpure CJ | The uptake and release of lysosomal enzymes by isolated perfused rat liver. | 1980 | Biochem. Soc. Trans. | pmid:6778741 |
Drewes LR et al. | Inhibition of unidirectional influx of glucose into the isolated perfused dog brain by cytochalasin B. | 1976 | Biochem. Soc. Trans. | pmid:1001606 |
Schmitt M and Bültmann B | Fluorescent chemotactic peptides as tools to identify the f-Met-Leu-Phe receptor on human granulocytes. | 1990 | Biochem. Soc. Trans. | pmid:2379691 |
Brant AM et al. | Immunological identification of five members of the human facilitative glucose transporter family. | 1992 | Biochem. Soc. Trans. | pmid:1426534 |
O'Dowd Y and Newsholme P | Regulation of superoxide production in human polymorphonuclear leukocytes (PMNs). | 1997 | Biochem. Soc. Trans. | pmid:9191411 |
Charalambous BM et al. | Detection of proton-linked sugar transport proteins in Enterobacteriaceae. | 1989 | Biochem. Soc. Trans. | pmid:2546838 |
Hales CN et al. | Sugar transport in lysosomes? | 1982 | Biochem. Soc. Trans. | pmid:7199491 |
Jones MN and Nickson JK | The human erythrocyte monosaccharide transporter in bilayer lipid membranes. | 1982 | Biochem. Soc. Trans. | pmid:7199492 |
Haslam RJ and Lynham JA | Increased phosphorylation of specific blood platelet proteins in association with the release reaction. | 1976 | Biochem. Soc. Trans. | pmid:187490 |
Dean RT | Effects of cytochalasin B on the pinocytosis and degradation of proteins by macrophages [proceedings]. | 1979 | Biochem. Soc. Trans. | pmid:570939 |
Gallo SA et al. | HIV-1 gp41 six-helix bundle formation occurs rapidly after the engagement of gp120 by CXCR4 in the HIV-1 Env-mediated fusion process. | 2001 | Biochemistry | pmid:11591141 |
Tsukamoto T et al. | Adenosine cyclic 3',5'-monophosphate uptake and regulation of membrane protein kinase in intact human erythrocytes. | 1980 | Biochemistry | pmid:6243958 |
Carruthers A and Melchior DL | Human erythrocyte hexose transporter activity is governed by bilayer lipid composition in reconstituted vesicles. | 1984 | Biochemistry | pmid:6543323 |
Schürmann A et al. | Role of conserved arginine and glutamate residues on the cytosolic surface of glucose transporters for transporter function. | 1997 | Biochemistry | pmid:9335548 |
May JM et al. | Tryptic digestion of the human erythrocyte glucose transporter: effects on ligand binding and tryptophan fluorescence. | 1993 | Biochemistry | pmid:8373759 |
King AP et al. | Cytochalasin B interferes with conformational changes of the human erythrocyte glucose transporter induced by internal and external sugar binding. | 1991 | Biochemistry | pmid:1747373 |
May JM and Beechem JM | Monitoring conformational change in the human erythrocyte glucose carrier: use of a fluorescent probe attached to an exofacial carrier sulfhydryl. | 1993 | Biochemistry | pmid:8457556 |
Gorga FR and Lienhard GE | Equilibria and kinetics of ligand binding to the human erythrocyte glucose transporter. Evidence for an alternating conformation model for transport. | 1981 | Biochemistry | pmid:7295669 |
Cloherty EK et al. | Regulation of GLUT1-mediated sugar transport by an antiport/uniport switch mechanism. | 1996 | Biochemistry | pmid:8855962 |
Axelrod JD and Pilch PF | Unique cytochalasin B binding characteristics of the hepatic glucose carrier. | 1983 | Biochemistry | pmid:6683102 |
Shanahan MF | Characterization of cytochalasin B photoincorporation into human erythrocyte D-glucose transporter and F-actin. | 1983 | Biochemistry | pmid:6683567 |
Tai PK and Carter-Su C | Monoclonal antibody to the human glucose transporter that differentiates between the glucose and nucleoside transporters. | 1988 | Biochemistry | pmid:3191107 |
Reyes AM et al. | Nicotinamide is not a substrate of the facilitative hexose transporter GLUT1. | 2002 | Biochemistry | pmid:12069599 |
Blodgett DM and Carruthers A | Quench-flow analysis reveals multiple phases of GluT1-mediated sugar transport. | 2005 | Biochemistry | pmid:15709778 |
May JM et al. | Localization of a reactive exofacial sulfhydryl on the glucose carrier of human erythrocytes. | 1990 | Biochemistry | pmid:2261480 |
Sampath P and Pollard TD | Effects of cytochalasin, phalloidin, and pH on the elongation of actin filaments. | 1991 | Biochemistry | pmid:1899622 |
Sultzman LA and Carruthers A | Stop-flow analysis of cooperative interactions between GLUT1 sugar import and export sites. | 1999 | Biochemistry | pmid:10350483 |