CYTOCHALASIN B

CYTOCHALASIN B is a lipid of Polyketides (PK) class. Cytochalasin b is associated with abnormalities such as Renal tubular disorder and Chagas Disease. The involved functions are known as Membrane Protein Traffic, inhibitors, Metabolic Inhibition, Biochemical Pathway and Increased Sensitivy. Cytochalasin b often locates in Cytoplasmic matrix, Plasma membrane, Microtubules, Extracellular and Protoplasm. The associated genes with CYTOCHALASIN B are SLC2A2 gene, PFDN5 gene, SLC2A1 gene, OMG gene and SPEN gene. The related lipids are Steroids, Lipopolysaccharides and Liposomes. The related experimental models are Xenograft Model.

Cross Reference

Introduction

To understand associated biological information of CYTOCHALASIN B, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with CYTOCHALASIN B?

CYTOCHALASIN B is suspected in Renal tubular disorder, Chagas Disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with CYTOCHALASIN B

MeSH term MeSH ID Detail
Chondrosarcoma D002813 9 associated lipids
Anemia D000740 21 associated lipids
Hyperinsulinism D006946 27 associated lipids
Congenital Abnormalities D000013 11 associated lipids
Carcinoma 256, Walker D002279 22 associated lipids
Thymus Neoplasms D013953 15 associated lipids
Wiskott-Aldrich Syndrome D014923 3 associated lipids
Erythroblastosis, Fetal D004899 2 associated lipids
Micronuclei, Chromosome-Defective D048629 33 associated lipids
Medulloblastoma D008527 22 associated lipids
Systemic Inflammatory Response Syndrome D018746 4 associated lipids
Insulin Resistance D007333 99 associated lipids
Aggressive Periodontitis D010520 8 associated lipids
Glucose Intolerance D018149 13 associated lipids
Granulomatosis with Polyangiitis D014890 5 associated lipids
Hypoxia-Ischemia, Brain D020925 22 associated lipids
Endometrial Neoplasms D016889 30 associated lipids
Malaria, Falciparum D016778 22 associated lipids
Lymphoma, B-Cell D016393 24 associated lipids
Lymphoma, T-Cell D016399 11 associated lipids
Cell Transformation, Viral D002472 26 associated lipids
Infectious Mononucleosis D007244 5 associated lipids
Ataxia Telangiectasia D001260 6 associated lipids
Pharyngeal Neoplasms D010610 4 associated lipids
Coronavirus Infections D018352 4 associated lipids
Chancroid D002602 4 associated lipids
Trisomy D014314 6 associated lipids
CREST Syndrome D017675 2 associated lipids
Factor XII Deficiency D005175 2 associated lipids
Per page 10 20 50 100 | Total 79

PubChem Associated disorders and diseases

What pathways are associated with CYTOCHALASIN B

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with CYTOCHALASIN B?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with CYTOCHALASIN B?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with CYTOCHALASIN B?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with CYTOCHALASIN B?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with CYTOCHALASIN B?

Xenograft Model

Xenograft Model are used in the study 'Endofacial competitive inhibition of the glucose transporter 1 activity by gossypol.' (Pérez A et al., 2009).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with CYTOCHALASIN B

Download all related citations
Per page 10 20 50 100 | Total 4982
Authors Title Published Journal PubMed Link
Panem S and Kirsten WH Effects of metabolic inhibitors on oncornavirus production during synchronized cell growth. 1975 Bibl Haematol pmid:183717
Lan GC et al. Demecolcine-assisted enucleation of goat oocytes: protocol optimization, mechanism investigation, and application to improve the developmental potential of cloned embryos. 2008 Cloning Stem Cells pmid:18373477
Schmitt M et al. Human tumor cell urokinase-type plasminogen activator (uPA): degradation of the proenzyme form (pro-uPA) by granulocyte elastase prevents subsequent activation by plasmin. 1991 Adv. Exp. Med. Biol. pmid:1837419
Steyn PS et al. Synthesis, complete 1H and 13C NMR assignment and crystal structure of novel epoxide derivatives of cytochalasin B. 2008 Magn Reson Chem pmid:18389494
Nakagawara A et al. Action of cytochalasin E on polymorphonuclear leucocytes of guinea pig peritoneal exudates. 1976 Exp. Cell Res. pmid:183965
Sugimura S et al. Effect of cytochalasins B and D on the developmental competence of somatic cell nuclear transfer embryos in miniature pigs. 2008 Zygote pmid:18405436
Wassarman PM et al. Cytochalasin B-induced pseudo-cleavage of mouse oocytes in vitro: asymmetric localization of mitochondria and microvilli associated with a stage-specific response. 1976 J. Cell. Sci. pmid:184100
Araújo JR et al. Modulation of glucose uptake in a human choriocarcinoma cell line (BeWo) by dietary bioactive compounds and drugs of abuse. 2008 J. Biochem. pmid:18424810
Arderiu G et al. External calcium facilitates signalling, contractile and secretory mechanisms induced after activation of platelets by collagen. 2008 Platelets pmid:18432518
Vu DM et al. Enhancement of permeability in endothelial cells for the development of an antithrombogenic bioartificial hemofilter. 2008 Biotechnol. Bioeng. pmid:18454501
Bauldry SA et al. Tumor necrosis factor-alpha priming of phospholipase A2 activation in human neutrophils. An alternative mechanism of priming. 1991 J. Immunol. pmid:1846897
Huang CK and Laramee GR Stimulation of a histone H4 protein kinase in Triton X-100 lysates of rabbit peritoneal neutrophils pretreated with chemotactic factors: effect of leukotriene B4 and cytochalasin B. 1991 J. Leukoc. Biol. pmid:1846903
Yu S et al. Hypoxic preconditioning up-regulates glucose transport activity and glucose transporter (GLUT1 and GLUT3) gene expression after acute anoxic exposure in the cultured rat hippocampal neurons and astrocytes. 2008 Brain Res. pmid:18474279
Bengtsson T et al. Actin assembly and regulation of neutrophil function: effects of cytochalasin B and tetracaine on chemotactic peptide-induced O2- production and degranulation. 1991 J. Leukoc. Biol. pmid:1847714
Bauldry SA et al. Tumor necrosis factor alpha priming of phospholipase D in human neutrophils. Correlation between phosphatidic acid production and superoxide generation. 1991 J. Biol. Chem. pmid:1847915
Wong K et al. Differential effect of diltiazem and TA-3090 on calcium homeostasis of neutrophils. 1991 Toxicol. Appl. Pharmacol. pmid:1848029
Naccache PH et al. Crystal-induced neutrophil activation. I. Initiation and modulation of calcium mobilization and superoxide production by microcrystals. 1991 Arthritis Rheum. pmid:1848432
Egan JJ et al. Parathyroid hormone promotes the disassembly of cytoskeletal actin and myosin in cultured osteoblastic cells: mediation by cyclic AMP. 1991 J. Cell. Biochem. pmid:1848561
Egan JJ et al. Cell density-dependent decrease in cytoskeletal actin and myosin in cultured osteoblastic cells: correlation with cyclic AMP changes. 1991 J. Cell. Biochem. pmid:1848564
Wardley RC et al. Polymorph-mediated antibody-dependent cytoxicity--modulation of activity by drugs and immune interferon. 1976 Can. J. Microbiol. pmid:184903
Balsamo J et al. Antibodies to the retina N-acetylgalactosaminylphosphotransferase modulate N-cadherin-mediated adhesion and uncouple the N-cadherin transferase complex from the actin-containing cytoskeleton. 1991 J. Cell Biol. pmid:1849140
Rossier MF et al. Subcellular distribution of the calcium-storing inositol 1,4,5-trisphosphate-sensitive organelle in rat liver. Possible linkage to the plasma membrane through the actin microfilaments. 1991 Biochem. J. pmid:1849402
Nurcombe HL et al. Neutrophils isolated from the synovial fluid of patients with rheumatoid arthritis: priming and activation in vivo. 1991 Ann. Rheum. Dis. pmid:1849716
Manara FS et al. Role of degranulation in activation of the respiratory burst in human neutrophils. 1991 J. Leukoc. Biol. pmid:1849954
English D and Taylor GS Divergent effects of propranolol on neutrophil superoxide release: involvement of phosphatidic acid and diacylglycerol as second messengers. 1991 Biochem. Biophys. Res. Commun. pmid:1850243
Cairns MT et al. Cytochalasin B as a probe of protein structure and substrate recognition by the galactose/H+ transporter of Escherichia coli. 1991 J. Biol. Chem. pmid:1850739
DiPasquale A and McGuire J MSH stimulates adenylate cyclase and tyrosinase in cultivated melanoma cells in the presence of cytochalasin B. 1976 Exp. Cell Res. pmid:185075
Terracciano S et al. Synthetic and pharmacological studies on new simplified analogues of the potent actin-targeting Jaspamide. 2008 Bioorg. Med. Chem. pmid:18508272
Waddell ID et al. Identification and characterization of a hepatic microsomal glucose transport protein. T3 of the glucose-6-phosphatase system? 1991 Biochem. J. pmid:1850983
Davies P and Allison AC The secretion of lysosomal enzymes. 1976 Front Biol pmid:185100
Van Obberghen E et al. Cell surface receptors for insulin and human growth hormone. Effect of microtubule and microfilament modifiers. 1976 J. Biol. Chem. pmid:185222
Busse WW and Lee TP Decreased adrenergic responses in lymphocytes and granulocytes in atopic eczema. 1976 J. Allergy Clin. Immunol. pmid:185243
Ito Y et al. The effects of cytochalasin and colchicine on interferon production. 1976 J. Gen. Virol. pmid:185321
Popova E et al. Efficient production of nuclear transferred rat embryos by modified methods of reconstruction. 2009 Mol. Reprod. Dev. pmid:18543283
Popov SV et al. Mechanism of cell protrusion formation in electrical field: the role of actin. 1991 Biochim. Biophys. Acta pmid:1854780
George TP et al. Inhibition of phosphatidylcholine and phosphatidylethanolamine biosynthesis by cytochalasin B in cultured glioma cells: potential regulation of biosynthesis by Ca(2+)-dependent mechanisms. 1991 Biochim. Biophys. Acta pmid:1854804
Lai CK et al. Association of hepatitis C virus replication complexes with microtubules and actin filaments is dependent on the interaction of NS3 and NS5A. 2008 J. Virol. pmid:18562541
Ai JS et al. Roles of microtubules and microfilaments in spindle movements during rat oocyte meiosis. 2008 J. Reprod. Dev. pmid:18594125
Lucas M and Solano F Opposite effect of cytochalasin B on agonist-induced respiratory burst in neutrophils and monocytes. 1991 Biochem. Pharmacol. pmid:1859454
Li X et al. Glucose and glucose transporters regulate lymphatic pump activity through activation of the mitochondrial ATP-sensitive K+ channel. 2008 J Physiol Sci pmid:18597699
Cimmino A et al. Production of phytotoxins by Phoma exigua var. exigua, a potential mycoherbicide against perennial thistles. 2008 J. Agric. Food Chem. pmid:18598037
Fellows MD et al. Comparison of different methods for an accurate assessment of cytotoxicity in the in vitro micronucleus test. II: Practical aspects with toxic agents. 2008 Aug-Sep Mutat. Res. pmid:18602493
Lorge E et al. Comparison of different methods for an accurate assessment of cytotoxicity in the in vitro micronucleus test. I. Theoretical aspects. 2008 Aug-Sep Mutat. Res. pmid:18602494
Yorek MA et al. Trans-hydroxyl group configuration on carbons 2 and 3 of glucose. Responsible for acute inhibition of myo-inositol transport? 1991 Diabetes pmid:1860553
Zijlstra C et al. Blastocyst morphology, actin cytoskeleton quality and chromosome content are correlated with embryo quality in the pig. 2008 Theriogenology pmid:18614224
Winchester JD et al. Hormone-induced dispersion or aggregation of carotenoid-containing smooth endoplasmic reticulum in cultured xanthophores from the goldfish, Carrassius auratus L. 1976 Endocr Res Commun pmid:186249
Greene WC et al. Cytochalasin sensitive structures and lymphocyte activation. 1976 Exp. Cell Res. pmid:186286
Farber FE and Eberle R Effects of cytochalasin and alkaloid drugs on the biological expression of herpes simplex virus type 2 DNA. 1976 Exp. Cell Res. pmid:186287
Casartelli M et al. A megalin-like receptor is involved in protein endocytosis in the midgut of an insect (Bombyx mori, Lepidoptera). 2008 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:18635456
Derbyshire ET et al. Identification, expression and characterisation of a Babesia bovis hexose transporter. 2008 Mol. Biochem. Parasitol. pmid:18638508