CYTOCHALASIN B is a lipid of Polyketides (PK) class. Cytochalasin b is associated with abnormalities such as Renal tubular disorder and Chagas Disease. The involved functions are known as Membrane Protein Traffic, inhibitors, Metabolic Inhibition, Biochemical Pathway and Increased Sensitivy. Cytochalasin b often locates in Cytoplasmic matrix, Plasma membrane, Microtubules, Extracellular and Protoplasm. The associated genes with CYTOCHALASIN B are SLC2A2 gene, PFDN5 gene, SLC2A1 gene, OMG gene and SPEN gene. The related lipids are Steroids, Lipopolysaccharides and Liposomes. The related experimental models are Xenograft Model.
To understand associated biological information of CYTOCHALASIN B, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
CYTOCHALASIN B is suspected in Renal tubular disorder, Chagas Disease and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with CYTOCHALASIN B
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Xenograft Model are used in the study 'Endofacial competitive inhibition of the glucose transporter 1 activity by gossypol.' (Pérez A et al., 2009).
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Authors | Title | Published | Journal | PubMed Link |
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O'Flaherty JT et al. | Neutrophil-degranulating action of 5,12-dihydroxy-6,8,10,14-eicosatetraenoic acid and 1-O-alkyl-2-O-acetyl-sn-glycero-3-phosphocholine. Comparison with other degranulating agents. | 1981 | Am. J. Pathol. | pmid:6274199 |
Elbim C et al. | Heterogeneity in Lewis-X and sialyl-Lewis-X antigen expression on monocytes in whole blood: relation to stimulus-induced oxidative burst. | 1998 | Am. J. Pathol. | pmid:9546369 |
Fantone JC et al. | Stimulus specificity of prostaglandin inhibition of rabbit polymorphonuclear leukocyte lysosomal enzyme release and superoxide anion production. | 1984 | Am. J. Pathol. | pmid:6324595 |
Okayasu T et al. | Cytochalasin delays but does not prevent cell death from anoxia. | 1984 | Am. J. Pathol. | pmid:6541879 |
O'Flaherty JT et al. | Substances which aggregate neutrophils. Mechanism of action. | 1978 | Am. J. Pathol. | pmid:356621 |
Ward PA et al. | Rat neutrophil activation and effects of lipoxygenase and cyclooxygenase inhibitors. | 1984 | Am. J. Pathol. | pmid:6087668 |
Hsu LS and Becker EL | Volume changes induced in rabbit polymorphonuclear leukocytes by chemotactic factor and cytochalasin B. | 1975 | Am. J. Pathol. | pmid:1180327 |
Ohta M et al. | Changes in the organization and antigenic determinants of intermediate filaments of rat hepatocytes after infusion of cytochalasin B in vivo. | 1988 | Am. J. Pathol. | pmid:2462355 |
White JG and Estensen RD | Cytochemical electron microscopic studies of the action of phorbol myristate acetate on platelets. | 1974 | Am. J. Pathol. | pmid:4814897 |
Lanni C and Becker EL | Release of phospholipase A2 activity from rabbit peritoneal neutrophils by f-Met-Leu-Phe. | 1983 | Am. J. Pathol. | pmid:6624881 |
Ogawa H et al. | Comparative study of eosinophil and neutrophil chemotaxis and enzyme release. | 1981 | Am. J. Pathol. | pmid:7294162 |
O'Flaherty JT et al. | Role of extracellular calcium and neutrophil degranulation responses to 1-O-alkyl-2-O-acetyl-sn-glycero-3-phosphocholine. | 1981 | Am. J. Pathol. | pmid:6271016 |
Mease AD et al. | Irreversible neutrophil aggregation. A mechanism of decreased newborn neutrophil chemotactic response. | 1981 | Am. J. Pathol. | pmid:7258298 |
White JG and Rao GH | Microtubule coils versus the surface membrane cytoskeleton in maintenance and restoration of platelet discoid shape. | 1998 | Am. J. Pathol. | pmid:9466587 |
Ingram DA et al. | Phagocytic activation of human neutrophils by the detergent component of fluosol. | 1992 | Am. J. Pathol. | pmid:1316083 |
Mukherjee C and Lynn WS | Role of ions and extracellular protein in leukocyte motility and membrane ruffling. | 1978 | Am. J. Pathol. | pmid:717536 |
Schollmeyer JV et al. | An actin-binding protein in human platelets. Interactions with alpha-actinin on gelatin of actin and the influence of cytochalasin B. | 1978 | Am. J. Pathol. | pmid:717537 |
Escolar G et al. | Organization of the actin cytoskeleton of resting and activated platelets in suspension. | 1986 | Am. J. Pathol. | pmid:2870643 |
White JG et al. | Glycoprotein Ib is homogeneously distributed on external and internal membranes of resting platelets. | 1999 | Am. J. Pathol. | pmid:10595941 |
Wysolmerski RB and Lagunoff D | Inhibition of endothelial cell retraction by ATP depletion. | 1988 | Am. J. Pathol. | pmid:3394800 |