CYTOCHALASIN B

CYTOCHALASIN B is a lipid of Polyketides (PK) class. Cytochalasin b is associated with abnormalities such as Renal tubular disorder and Chagas Disease. The involved functions are known as Membrane Protein Traffic, inhibitors, Metabolic Inhibition, Biochemical Pathway and Increased Sensitivy. Cytochalasin b often locates in Cytoplasmic matrix, Plasma membrane, Microtubules, Extracellular and Protoplasm. The associated genes with CYTOCHALASIN B are SLC2A2 gene, PFDN5 gene, SLC2A1 gene, OMG gene and SPEN gene. The related lipids are Steroids, Lipopolysaccharides and Liposomes. The related experimental models are Xenograft Model.

Cross Reference

Introduction

To understand associated biological information of CYTOCHALASIN B, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with CYTOCHALASIN B?

CYTOCHALASIN B is suspected in Renal tubular disorder, Chagas Disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with CYTOCHALASIN B

MeSH term MeSH ID Detail
Insulinoma D007340 28 associated lipids
Insulin Resistance D007333 99 associated lipids
Inflammation D007249 119 associated lipids
Infectious Mononucleosis D007244 5 associated lipids
Hypoglycemia D007003 13 associated lipids
Hypertension D006973 115 associated lipids
Hyperinsulinism D006946 27 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Hemolysis D006461 131 associated lipids
Granulomatous Disease, Chronic D006105 4 associated lipids
Glioma D005910 112 associated lipids
Galactosemias D005693 5 associated lipids
Foreign-Body Reaction D005549 10 associated lipids
Factor XII Deficiency D005175 2 associated lipids
Eye Diseases D005128 12 associated lipids
Leukemia, Erythroblastic, Acute D004915 41 associated lipids
Erythroblastosis, Fetal D004899 2 associated lipids
Diabetic Nephropathies D003928 39 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with CYTOCHALASIN B

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with CYTOCHALASIN B?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with CYTOCHALASIN B?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with CYTOCHALASIN B?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with CYTOCHALASIN B?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with CYTOCHALASIN B?

Xenograft Model

Xenograft Model are used in the study 'Endofacial competitive inhibition of the glucose transporter 1 activity by gossypol.' (Pérez A et al., 2009).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with CYTOCHALASIN B

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Authors Title Published Journal PubMed Link
Ohkuro M and Hishinuma I The alpha integrin cytoplasmic motif KXGFFKR is essential for integrin-mediated leukocyte adhesion. 2010 Int. J. Mol. Med. pmid:20127050
Johnsson AK and Karlsson R Microtubule-dependent localization of profilin I mRNA to actin polymerization sites in serum-stimulated cells. 2010 Eur. J. Cell Biol. pmid:20129697
Cai X et al. Connection between biomechanics and cytoskeleton structure of lymphocyte and Jurkat cells: An AFM study. 2010 Micron pmid:20060729
Cura AJ and Carruthers A Acute modulation of sugar transport in brain capillary endothelial cell cultures during activation of the metabolic stress pathway. 2010 J. Biol. Chem. pmid:20231288
Lowes DA et al. Dehydroascorbic acid as pre-conditioner: protection from lipopolysaccharide induced mitochondrial damage. 2010 Free Radic. Res. pmid:20166893
Gravett CM et al. Interactive inhibitory effects of formoterol and montelukast on activated human neutrophils. 2010 Eur. Respir. J. pmid:20413544
Xiao D et al. Pregnancy downregulates actin polymerization and pressure-dependent myogenic tone in ovine uterine arteries. 2010 Hypertension pmid:20855655
Nesslany F and Marzin D Cytosine arabinoside, vinblastine, diethylstilboestrol and 2-aminoanthracene tested in the in vitro human TK6 cell line micronucleus test (MNvit) at Institut Pasteur de Lille in support of OECD draft test guideline 487. 2010 Mutat. Res. pmid:20348020
Wang ZY et al. Actin microfilament involved in regulation of pacemaking activity in cultured interstitial cells of Cajal from murine intestine. 2010 J. Membr. Biol. pmid:20349180
Fowler P et al. Cadmium chloride, benzo[a]pyrene and cyclophosphamide tested in the in vitro mammalian cell micronucleus test (MNvit) in the human lymphoblastoid cell line TK6 at Covance laboratories, Harrogate UK in support of OECD draft Test Guideline 487. 2010 Mutat. Res. pmid:20206291
Hoki S et al. Enhancement of fibrinolysis by gel-filtered platelets and its quenching by cytochalasin B and GPIIb/IIIa antagonists. 2009 Sep-Oct Pharmacol Rep pmid:19904011
Sudarikova AV et al. [Functional properties of sodium channels in cholesterol-depleted K562 cells]. 2009 Tsitologiia pmid:19799352
Wang C et al. Analysis of cat oocyte activation methods for the generation of feline disease models by nuclear transfer. 2009 Reprod. Biol. Endocrinol. pmid:20003339
Gu S et al. Functional membrane androgen receptors in colon tumors trigger pro-apoptotic responses in vitro and reduce drastically tumor incidence in vivo. 2009 Mol. Cancer pmid:19948074
Zhang J et al. Improved development of ovine matured oocyte following solid surface vitrification (SSV): effect of cumulus cells and cytoskeleton stabilizer. 2009 Anim. Reprod. Sci. pmid:18242892
Opp D et al. Use of electric cell-substrate impedance sensing to assess in vitro cytotoxicity. 2009 Biosens Bioelectron pmid:19230649
Westphal GA et al. The benzene metabolite para-benzoquinone is genotoxic in human, phorbol-12-acetate-13-myristate induced, peripheral blood mononuclear cells at low concentrations. 2009 Arch. Toxicol. pmid:19212761
Cunnick JM et al. Bcr and Abr cooperate in negatively regulating acute inflammatory responses. 2009 Mol. Cell. Biol. pmid:19703997
Prager-Khoutorsky M and Spira ME Neurite retraction and regrowth regulated by membrane retrieval, membrane supply, and actin dynamics. 2009 Brain Res. pmid:19022228
Lovelady DC et al. Detecting effects of low levels of cytochalasin B in 3T3 fibroblast cultures by analysis of electrical noise obtained from cellular micromotion. 2009 Biosens Bioelectron pmid:19026529