CYTOCHALASIN B

CYTOCHALASIN B is a lipid of Polyketides (PK) class. Cytochalasin b is associated with abnormalities such as Renal tubular disorder and Chagas Disease. The involved functions are known as Membrane Protein Traffic, inhibitors, Metabolic Inhibition, Biochemical Pathway and Increased Sensitivy. Cytochalasin b often locates in Cytoplasmic matrix, Plasma membrane, Microtubules, Extracellular and Protoplasm. The associated genes with CYTOCHALASIN B are SLC2A2 gene, PFDN5 gene, SLC2A1 gene, OMG gene and SPEN gene. The related lipids are Steroids, Lipopolysaccharides and Liposomes. The related experimental models are Xenograft Model.

Cross Reference

Introduction

To understand associated biological information of CYTOCHALASIN B, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with CYTOCHALASIN B?

CYTOCHALASIN B is suspected in Renal tubular disorder, Chagas Disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with CYTOCHALASIN B

MeSH term MeSH ID Detail
Granulomatous Disease, Chronic D006105 4 associated lipids
Leukemia, Erythroblastic, Acute D004915 41 associated lipids
Melanoma D008545 69 associated lipids
Asthma D001249 52 associated lipids
Kidney Diseases D007674 29 associated lipids
Glioma D005910 112 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Lymphoma D008223 18 associated lipids
Alzheimer Disease D000544 76 associated lipids
Thyroid Neoplasms D013964 33 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with CYTOCHALASIN B

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with CYTOCHALASIN B?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with CYTOCHALASIN B?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with CYTOCHALASIN B?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with CYTOCHALASIN B?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with CYTOCHALASIN B?

Xenograft Model

Xenograft Model are used in the study 'Endofacial competitive inhibition of the glucose transporter 1 activity by gossypol.' (Pérez A et al., 2009).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with CYTOCHALASIN B

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Authors Title Published Journal PubMed Link
O'Flaherty JT et al. Neutrophil-degranulating action of 5,12-dihydroxy-6,8,10,14-eicosatetraenoic acid and 1-O-alkyl-2-O-acetyl-sn-glycero-3-phosphocholine. Comparison with other degranulating agents. 1981 Am. J. Pathol. pmid:6274199
Aikawa M et al. Interactions between macrophagelike cells and Leishmania braziliensis in vitro. 1982 Am. J. Pathol. pmid:7091302
Russo MA et al. Ultrastruct pathology of phalloidin-intoxicated hepatocytes in the presence and absence of extracellular calcium. 1982 Am. J. Pathol. pmid:6890315
Fantone JC et al. Stimulus specificity of prostaglandin inhibition of rabbit polymorphonuclear leukocyte lysosomal enzyme release and superoxide anion production. 1984 Am. J. Pathol. pmid:6324595
Okayasu T et al. Cytochalasin delays but does not prevent cell death from anoxia. 1984 Am. J. Pathol. pmid:6541879
Díaz-Ricart M et al. Inhibition of cytoskeletal assembly by cytochalasin B prevents signaling through tyrosine phosphorylation and secretion triggered by collagen but not by thrombin. 2002 Am. J. Pathol. pmid:11786426
Matsumura N et al. Stable expression in Chinese hamster ovary cells of mutated tau genes causing frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17). 1999 Am. J. Pathol. pmid:10362789
Ward PA et al. Rat neutrophil activation and effects of lipoxygenase and cyclooxygenase inhibitors. 1984 Am. J. Pathol. pmid:6087668
Hsu LS and Becker EL Volume changes induced in rabbit polymorphonuclear leukocytes by chemotactic factor and cytochalasin B. 1975 Am. J. Pathol. pmid:1180327
Ohta M et al. Changes in the organization and antigenic determinants of intermediate filaments of rat hepatocytes after infusion of cytochalasin B in vivo. 1988 Am. J. Pathol. pmid:2462355
White JG and Estensen RD Cytochemical electron microscopic studies of the action of phorbol myristate acetate on platelets. 1974 Am. J. Pathol. pmid:4814897
Lanni C and Becker EL Release of phospholipase A2 activity from rabbit peritoneal neutrophils by f-Met-Leu-Phe. 1983 Am. J. Pathol. pmid:6624881
Ogawa H et al. Comparative study of eosinophil and neutrophil chemotaxis and enzyme release. 1981 Am. J. Pathol. pmid:7294162
O'Flaherty JT et al. Role of extracellular calcium and neutrophil degranulation responses to 1-O-alkyl-2-O-acetyl-sn-glycero-3-phosphocholine. 1981 Am. J. Pathol. pmid:6271016
Holland JA et al. Atherogenic levels of low-density lipoprotein increase endocytotic activity in cultured human endothelial cells. 1992 Am. J. Pathol. pmid:1546741
Ingram DA et al. Phagocytic activation of human neutrophils by the detergent component of fluosol. 1992 Am. J. Pathol. pmid:1316083
Mukherjee C and Lynn WS Role of ions and extracellular protein in leukocyte motility and membrane ruffling. 1978 Am. J. Pathol. pmid:717536
Schollmeyer JV et al. An actin-binding protein in human platelets. Interactions with alpha-actinin on gelatin of actin and the influence of cytochalasin B. 1978 Am. J. Pathol. pmid:717537
Escolar G et al. Organization of the actin cytoskeleton of resting and activated platelets in suspension. 1986 Am. J. Pathol. pmid:2870643
Wysolmerski RB and Lagunoff D Inhibition of endothelial cell retraction by ATP depletion. 1988 Am. J. Pathol. pmid:3394800