CYTOCHALASIN B

CYTOCHALASIN B is a lipid of Polyketides (PK) class. Cytochalasin b is associated with abnormalities such as Renal tubular disorder and Chagas Disease. The involved functions are known as Membrane Protein Traffic, inhibitors, Metabolic Inhibition, Biochemical Pathway and Increased Sensitivy. Cytochalasin b often locates in Cytoplasmic matrix, Plasma membrane, Microtubules, Extracellular and Protoplasm. The associated genes with CYTOCHALASIN B are SLC2A2 gene, PFDN5 gene, SLC2A1 gene, OMG gene and SPEN gene. The related lipids are Steroids, Lipopolysaccharides and Liposomes. The related experimental models are Xenograft Model.

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Introduction

To understand associated biological information of CYTOCHALASIN B, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with CYTOCHALASIN B?

CYTOCHALASIN B is suspected in Renal tubular disorder, Chagas Disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with CYTOCHALASIN B

MeSH term MeSH ID Detail
Melanoma D008545 69 associated lipids
Leukemia D007938 74 associated lipids
Alzheimer Disease D000544 76 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Arteriosclerosis D001161 86 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Insulin Resistance D007333 99 associated lipids
Glioma D005910 112 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with CYTOCHALASIN B

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with CYTOCHALASIN B?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with CYTOCHALASIN B?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with CYTOCHALASIN B?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with CYTOCHALASIN B?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with CYTOCHALASIN B?

Xenograft Model

Xenograft Model are used in the study 'Endofacial competitive inhibition of the glucose transporter 1 activity by gossypol.' (Pérez A et al., 2009).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with CYTOCHALASIN B

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Authors Title Published Journal PubMed Link
Russo MA et al. Ultrastruct pathology of phalloidin-intoxicated hepatocytes in the presence and absence of extracellular calcium. 1982 Am. J. Pathol. pmid:6890315
Fantone JC et al. Stimulus specificity of prostaglandin inhibition of rabbit polymorphonuclear leukocyte lysosomal enzyme release and superoxide anion production. 1984 Am. J. Pathol. pmid:6324595
Becker EL et al. Superoxide production induced in rabbit polymorphonuclear leukocytes by synthetic chemotactic peptides and A23187. 1979 Am. J. Pathol. pmid:219701
Díaz-Ricart M et al. Inhibition of cytoskeletal assembly by cytochalasin B prevents signaling through tyrosine phosphorylation and secretion triggered by collagen but not by thrombin. 2002 Am. J. Pathol. pmid:11786426
O'Flaherty JT et al. Neutrophil aggregation and degranulation. Effect of arachidonic acid. 1979 Am. J. Pathol. pmid:453323
Matsumura N et al. Stable expression in Chinese hamster ovary cells of mutated tau genes causing frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17). 1999 Am. J. Pathol. pmid:10362789
O'Flaherty JT et al. 1-O-Alkyl-sn-glyceryl-3-phosphorylcholines: a novel class of neutrophil stimulants. 1981 Am. J. Pathol. pmid:7223864
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Hsu LS and Becker EL Volume changes induced in rabbit polymorphonuclear leukocytes by chemotactic factor and cytochalasin B. 1975 Am. J. Pathol. pmid:1180327
Ohta M et al. Changes in the organization and antigenic determinants of intermediate filaments of rat hepatocytes after infusion of cytochalasin B in vivo. 1988 Am. J. Pathol. pmid:2462355
Ulevitch RJ et al. Hyperexpression of interferon-gamma-induced MHC class II genes associated with reorganization of the cytoskeleton. 1991 Am. J. Pathol. pmid:1907805
Lanni C and Becker EL Release of phospholipase A2 activity from rabbit peritoneal neutrophils by f-Met-Leu-Phe. 1983 Am. J. Pathol. pmid:6624881
Mease AD et al. Irreversible neutrophil aggregation. A mechanism of decreased newborn neutrophil chemotactic response. 1981 Am. J. Pathol. pmid:7258298
White JG and Rao GH Microtubule coils versus the surface membrane cytoskeleton in maintenance and restoration of platelet discoid shape. 1998 Am. J. Pathol. pmid:9466587
Mukherjee C and Lynn WS Role of ions and extracellular protein in leukocyte motility and membrane ruffling. 1978 Am. J. Pathol. pmid:717536
Schollmeyer JV et al. An actin-binding protein in human platelets. Interactions with alpha-actinin on gelatin of actin and the influence of cytochalasin B. 1978 Am. J. Pathol. pmid:717537
Webster RO et al. Enhancement of human polymorphonuclear leukocyte adherence to plastic and endothelium by phorbol myristate acetate. Comparison with human C5a. 1986 Am. J. Pathol. pmid:3789092
Ginsberg M et al. Mechanisms of platelet response to monosodium urate crystals. 1979 Am. J. Pathol. pmid:426039
White JG et al. Glycoprotein Ib is homogeneously distributed on external and internal membranes of resting platelets. 1999 Am. J. Pathol. pmid:10595941