CYTOCHALASIN B

CYTOCHALASIN B is a lipid of Polyketides (PK) class. Cytochalasin b is associated with abnormalities such as Renal tubular disorder and Chagas Disease. The involved functions are known as Membrane Protein Traffic, inhibitors, Metabolic Inhibition, Biochemical Pathway and Increased Sensitivy. Cytochalasin b often locates in Cytoplasmic matrix, Plasma membrane, Microtubules, Extracellular and Protoplasm. The associated genes with CYTOCHALASIN B are SLC2A2 gene, PFDN5 gene, SLC2A1 gene, OMG gene and SPEN gene. The related lipids are Steroids, Lipopolysaccharides and Liposomes. The related experimental models are Xenograft Model.

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Introduction

To understand associated biological information of CYTOCHALASIN B, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with CYTOCHALASIN B?

CYTOCHALASIN B is suspected in Renal tubular disorder, Chagas Disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with CYTOCHALASIN B

MeSH term MeSH ID Detail
Erythroblastosis, Fetal D004899 2 associated lipids
CREST Syndrome D017675 2 associated lipids
Factor XII Deficiency D005175 2 associated lipids
Wiskott-Aldrich Syndrome D014923 3 associated lipids
Pharyngeal Neoplasms D010610 4 associated lipids
Pituitary Neoplasms D010911 4 associated lipids
Coronavirus Infections D018352 4 associated lipids
Chancroid D002602 4 associated lipids
Granulomatous Disease, Chronic D006105 4 associated lipids
Systemic Inflammatory Response Syndrome D018746 4 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with CYTOCHALASIN B

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with CYTOCHALASIN B?

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What functions are associated with CYTOCHALASIN B?


Related references are published most in these journals:

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What lipids are associated with CYTOCHALASIN B?

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What genes are associated with CYTOCHALASIN B?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with CYTOCHALASIN B?

Xenograft Model

Xenograft Model are used in the study 'Endofacial competitive inhibition of the glucose transporter 1 activity by gossypol.' (Pérez A et al., 2009).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with CYTOCHALASIN B

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Authors Title Published Journal PubMed Link
Parry JM and Kirsch-Volders M Special issue on in vitro MN trial. 2010 Mutat. Res. pmid:20654729
Kirkland D Evaluation of different cytotoxic and cytostatic measures for the in vitro micronucleus test (MNVit): summary of results in the collaborative trial. 2010 Mutat. Res. pmid:20149894
Kirkland D Evaluation of different cytotoxic and cytostatic measures for the in vitro micronucleus test (MNVit): introduction to the collaborative trial. 2010 Mutat. Res. pmid:20176128
Johnston PJ et al. Induction and distribution of damage in CHO-K1 and the X-ray-sensitive hamster cell line xrs5, measured by the cytochalasin-B-cytokinesis block micronucleus assay. 1997 Mutat. Res. pmid:9372843
Krishna G et al. Use of the cytokinesis-block method for the analysis of micronuclei in V79 Chinese hamster lung cells: results with mitomycin C and cyclophosphamide. 1989 Mutat. Res. pmid:2492079
Dimitrijević A et al. Micronucleus frequency in women with genital Chlamydia Trachomatis infection before and after therapy. 2006 Mutat. Res. pmid:16777475
Erexson GL et al. Diaziquone-induced micronuclei in cytochalasin B-blocked mouse peripheral blood lymphocytes. 1987 Mutat. Res. pmid:3574322
Wakata A and Sasaki MS Measurement of micronuclei by cytokinesis-block method in cultured Chinese hamster cells: comparison with types and rates of chromosome aberrations. 1987 Mutat. Res. pmid:3099194
Lynch AM and Parry JM The cytochalasin-B micronucleus/kinetochore assay in vitro: studies with 10 suspected aneugens. 1993 Mutat. Res. pmid:7683386
Antoccia A et al. Cytokinesis-block micronucleus assay with kinetochore detection in colchicine-treated human fibroblasts. 1993 Mutat. Res. pmid:7683388
Kligerman AD and Erexson GL An evaluation of the feasibility of using cytogenetic damage as a biomarker for alachlor exposure. 1999 Mutat. Res. pmid:10224326
Aardema MJ et al. SFTG international collaborative study on in vitro micronucleus test III. Using CHO cells. 2006 Mutat. Res. pmid:16797224
Curren RD et al. Development of a method for assessing micronucleus induction in a 3D human skin model (EpiDerm). 2006 Mutat. Res. pmid:16781186
Wakata A et al. SFTG international collaborative study on in vitro micronucleus test IV. Using CHL cells. 2006 Mutat. Res. pmid:16782396
Lorge E et al. SFTG international collaborative study on in vitro micronucleus test I. General conditions and overall conclusions of the study. 2006 Mutat. Res. pmid:16815079
Fenech M and Morley AA Cytokinesis-block micronucleus method in human lymphocytes: effect of in vivo ageing and low dose X-irradiation. 1986 Mutat. Res. pmid:3724773
Mun GC et al. Further development of the EpiDerm 3D reconstructed human skin micronucleus (RSMN) assay. 2009 Mutat. Res. pmid:19167515
Chang WP et al. Follow-up in the micronucleus frequencies and its subsets in human population with chronic low-dose gamma-irradiation exposure. 1999 Mutat. Res. pmid:10517983
Phelps JB et al. A protocol for the in vitro micronucleus test. II. Contributions to the validation of a protocol suitable for regulatory submissions from an examination of 10 chemicals with different mechanisms of action and different levels of activity. 2002 Mutat. Res. pmid:12438008
Fellows MD et al. Comparison of different methods for an accurate assessment of cytotoxicity in the in vitro micronucleus test. II: Practical aspects with toxic agents. 2008 Aug-Sep Mutat. Res. pmid:18602493
Lorge E et al. Comparison of different methods for an accurate assessment of cytotoxicity in the in vitro micronucleus test. I. Theoretical aspects. 2008 Aug-Sep Mutat. Res. pmid:18602494
Stopper H et al. Micronucleus induction by neocarzinostatin and methyl methanesulfonate in ionizing radiation--sensitive Chinese hamster V79 cell mutants. 1997 Mutat. Res. pmid:9088343
Fenech M and Morley AA Measurement of micronuclei in lymphocytes. 1985 Feb-Apr Mutat. Res. pmid:3974610
Terzoudi GI et al. Stress induced by premature chromatin condensation triggers chromosome shattering and chromothripsis at DNA sites still replicating in micronuclei or multinucleate cells when primary nuclei enter mitosis. 2015 Mutat Res Genet Toxicol Environ Mutagen pmid:26520389
Hatzi VI et al. Low concentrations of caffeine induce asymmetric cell division as observed in vitro by means of the CBMN-assay and iFISH. 2015 Mutat Res Genet Toxicol Environ Mutagen pmid:26520375
Whitwell J et al. Relationships between p53 status, apoptosis and induction of micronuclei in different human and mouse cell lines in vitro: Implications for improving existing assays. 2015 Mutat Res Genet Toxicol Environ Mutagen pmid:26232254
Matsushima T et al. Validation study of the in vitro micronucleus test in a Chinese hamster lung cell line (CHL/IU). 1999 Mutagenesis pmid:10567032
Fenech M et al. Necrosis, apoptosis, cytostasis and DNA damage in human lymphocytes measured simultaneously within the cytokinesis-block micronucleus assay: description of the method and results for hydrogen peroxide. 1999 Mutagenesis pmid:10567036
Tomanin R et al. Influence of smoking habit on the frequency of micronuclei in human lymphocytes by the cytokinesis block method. 1991 Mutagenesis pmid:2056912
Norppa H et al. Detection of whole chromosomes in micronuclei of cytokinesis-blocked human lymphocytes by antikinetochore staining and in situ hybridization. 1993 Mutagenesis pmid:8133781
Slavotinek A et al. A comparison of micronucleus frequency and radiation survival in lymphoblastoid cell lines. 1993 Mutagenesis pmid:8133787
Schultz N and Onfelt A Video time-lapse study of mitosis in binucleate V79 cells: chromosome segregation and cleavage. 1994 Mutagenesis pmid:8201944
Crott J and Fenech M Preliminary study of the genotoxic potential of homocysteine in human lymphocytes in vitro. 2001 Mutagenesis pmid:11320146
de Stoppelaar JM et al. In vivo cytokinesis blocked micronucleus assay with carbendazim in rat fibroblasts and comparison with in vitro assays. 2000 Mutagenesis pmid:10719042
Castelain P et al. Automated detection of cytochalasin-B blocked binucleated lymphocytes for scoring micronuclei. 1993 Mutagenesis pmid:7690875
Varga D et al. An automated scoring procedure for the micronucleus test by image analysis. 2004 Mutagenesis pmid:15388812
Surrallés J et al. A collaborative study on the improvement of the micronucleus test in cultured human lymphocytes. 1992 Mutagenesis pmid:1474915
Van Hummelen P and Kirsch-Volders M Analysis of eight known or suspected aneugens by the in vitro human lymphocyte micronucleus test. 1992 Mutagenesis pmid:1474920
Cakmak Demircigil G et al. Micronucleus frequencies in peripheral blood lymphocytes of children with chronic kidney disease. 2011 Mutagenesis pmid:21669938
Burgaz S et al. Micronucleus frequencies in lymphocytes and buccal epithelial cells from patients having head and neck cancer and their first-degree relatives. 2011 Mutagenesis pmid:21248276
Zijno A et al. Simultaneous detection of X-chromosome loss and non-disjunction in cytokinesis-blocked human lymphocytes by in situ hybridization with a centromeric DNA probe; implications for the human lymphocyte in vitro micronucleus assay using cytochalasin B. 1994 Mutagenesis pmid:7934962
Nesslany F and Marzin D A micromethod for the in vitro micronucleus assay. 1999 Mutagenesis pmid:10390508
Guccini S et al. Effects of spindle poisons in peripheral human lymphocytes by the in vitro cytokinesis-block micronucleus assay. 2012 Mutagenesis pmid:22952150
Touil N et al. Analysis of chromosome loss and chromosome segregation in cytokinesis-blocked human lymphocytes: non-disjunction is the prevalent mistake in chromosome segregation produced by low dose exposure to ionizing radiation. 2000 Mutagenesis pmid:10640524
Oliveira NG et al. Assessment of the adaptive response induced by quercetin using the MNCB peripheral blood human lymphocytes assay. 2000 Mutagenesis pmid:10640534
Arsoy NS et al. Micronuclei in peripheral blood from patients after cytostatic therapy mainly arise ex vivo from persistent damage. 2009 Mutagenesis pmid:19423564
Heddle JA et al. Concurrent detection of gene mutations and chromosomal aberrations induced in vivo in somatic cells. 1990 Mutagenesis pmid:2188072
Surrallés J et al. The effect of cytochalasin-B concentration on the frequency of micronuclei induced by four standard mutagens. Results from two laboratories. 1994 Mutagenesis pmid:7968577
Minissi S et al. Direct and indirect non-disjunction in the origin of trisomy in cultured human lymphocytes. 1999 Mutagenesis pmid:10567030
Cimini D et al. Differences in malsegregation rates obtained by scoring ana-telophases or binucleate cells. 1999 Mutagenesis pmid:10567031