CYTOCHALASIN B

CYTOCHALASIN B is a lipid of Polyketides (PK) class. Cytochalasin b is associated with abnormalities such as Renal tubular disorder and Chagas Disease. The involved functions are known as Membrane Protein Traffic, inhibitors, Metabolic Inhibition, Biochemical Pathway and Increased Sensitivy. Cytochalasin b often locates in Cytoplasmic matrix, Plasma membrane, Microtubules, Extracellular and Protoplasm. The associated genes with CYTOCHALASIN B are SLC2A2 gene, PFDN5 gene, SLC2A1 gene, OMG gene and SPEN gene. The related lipids are Steroids, Lipopolysaccharides and Liposomes. The related experimental models are Xenograft Model.

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Introduction

To understand associated biological information of CYTOCHALASIN B, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with CYTOCHALASIN B?

CYTOCHALASIN B is suspected in Renal tubular disorder, Chagas Disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with CYTOCHALASIN B

MeSH term MeSH ID Detail
Micronuclei, Chromosome-Defective D048629 33 associated lipids
Hypoxia-Ischemia, Brain D020925 22 associated lipids
Systemic Inflammatory Response Syndrome D018746 4 associated lipids
Coronavirus Infections D018352 4 associated lipids
Glucose Intolerance D018149 13 associated lipids
CREST Syndrome D017675 2 associated lipids
Endometrial Neoplasms D016889 30 associated lipids
Malaria, Falciparum D016778 22 associated lipids
Lymphoma, T-Cell D016399 11 associated lipids
Lymphoma, B-Cell D016393 24 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with CYTOCHALASIN B

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with CYTOCHALASIN B?

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What functions are associated with CYTOCHALASIN B?


Related references are published most in these journals:

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What lipids are associated with CYTOCHALASIN B?

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What genes are associated with CYTOCHALASIN B?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with CYTOCHALASIN B?

Xenograft Model

Xenograft Model are used in the study 'Endofacial competitive inhibition of the glucose transporter 1 activity by gossypol.' (Pérez A et al., 2009).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with CYTOCHALASIN B

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Authors Title Published Journal PubMed Link
Michelakakis H and Danpure CJ The effect of cytochalasin B on the release of lysosomal enzymes and intra-lysosomally-stored polyvinylpyrrolidone in the isolated perfused rat liver. 1984 Biochem. Pharmacol. pmid:6430298
Elferink JG Chlorpromazine inhibits phagocytosis and exocytosis in rabbit polymorphonuclear leukocytes. 1979 Biochem. Pharmacol. pmid:375938
Tsuruo T and Iida H Effects of cytochalasins and colchicine on the accumulation and retention of daunomycin and vincristine in drug resistant tumor cells. 1986 Biochem. Pharmacol. pmid:3457567
Skidgel RA et al. Metabolism of substance P and bradykinin by human neutrophils. 1991 Biochem. Pharmacol. pmid:1708255
Smith RJ and Iden SS Pharmacological modulation of chemotactic factor-elicited release of granule-associated enzymes from human neutrophils. Effects of prostaglandins, nonsteroid anti-inflammatory agents and corticosteroids. 1980 Biochem. Pharmacol. pmid:7426044
Theodoropoulos PA et al. Cytochalasin B may shorten actin filaments by a mechanism independent of barbed end capping. 1994 Biochem. Pharmacol. pmid:8204105
Smith RJ et al. Stimulation of the human neutrophil superoxide anion-generating system with 1-O-hexadecyl/octadecyl-2-acetyl-sn-glyceryl-3- phosphorylcholine. 1984 Biochem. Pharmacol. pmid:6324816
Dayer JM et al. Effects of prostaglandin E2, indomethacin, trifluoperazine and drugs affecting the cytoskeleton on collagenase production by cultured adherent rheumatoid synovial cells. 1984 Biochem. Pharmacol. pmid:6089839
Zhou HL et al. Association between leukotriene B4-induced phospholipase D activation and degranulation of human neutrophils. 1993 Biochem. Pharmacol. pmid:8394074
Fujita H et al. Involvement of Ras/extracellular signal-regulated kinase, but not Akt pathway in risedronate-induced apoptosis of U937 cells and its suppression by cytochalasin B. 2005 Biochem. Pharmacol. pmid:15869745
Michelakakis H and Danpure CJ The release of intralysosomally-stored 125I-Triton WR-1339 and lysosomal enzymes from the isolated perfused rat liver in the presence and absence of cytochalasin B. 1986 Biochem. Pharmacol. pmid:3082335
Soares-da-Silva P Actin cytoskeleton, tubular sodium and the renal synthesis of dopamine. 1992 Biochem. Pharmacol. pmid:1449540
DoKhac L et al. Differential role of microtubules in the control of prostaglandin E2 and beta-adrenergic stimulation of cyclic AMP accumulation in the rat myometrium. 1983 Biochem. Pharmacol. pmid:6193795
Trush MA et al. Oxidant-mediated electronic excitation of imipramine. 1984 Biochem. Pharmacol. pmid:6329228
Lucas M and Solano F Opposite effect of cytochalasin B on agonist-induced respiratory burst in neutrophils and monocytes. 1991 Biochem. Pharmacol. pmid:1859454
Kim JY et al. Src-mediated regulation of inflammatory responses by actin polymerization. 2010 Biochem. Pharmacol. pmid:19769947
Malaisse WJ et al. The coupling of metabolic to secretory events in pancreatic islets: inhibition by 2-cyclohexene-1-one of the secretory response to cyclic AMP and cytochalasin B. 1986 Biochem. Pharmacol. pmid:2877668
Smith RJ Phagocytic release of lysosomal enzymes from guinea pig neutrophils--regulation by corticosteroids, autonomic neurohormones and cyclic nucleotides. 1977 Biochem. Pharmacol. pmid:21664
Stournaras C et al. Altered actin polymerization dynamics in various malignant cell types: evidence for differential sensitivity to cytochalasin B. 1996 Biochem. Pharmacol. pmid:8937443
Morita K et al. Effects of cytoskeleton-disrupting drugs on ouabain-stimulated catecholamine secretion from cultured adrenal chromaffin cells. 1988 Biochem. Pharmacol. pmid:3401261
Michelakakis H and Danpure CJ The effect of cytochalasin B on the release of lysosomal enzymes from isolated rat hepatocytes [proceedings]. 1979 Biochem. Soc. Trans. pmid:119657
Walmsley AR et al. The pre-steady-state kinetics of conformational changes in sugar transporters. 1994 Biochem. Soc. Trans. pmid:7821656
al-Habori M et al. Cytochalasins potently inhibit glycogen synthesis in hepatocyte cultures by an indirect mechanism. 1991 Biochem. Soc. Trans. pmid:1794472
Michelakakis H and Danpure CJ The uptake and release of lysosomal enzymes by isolated perfused rat liver. 1980 Biochem. Soc. Trans. pmid:6778741
Drewes LR et al. Inhibition of unidirectional influx of glucose into the isolated perfused dog brain by cytochalasin B. 1976 Biochem. Soc. Trans. pmid:1001606
Schmitt M and Bültmann B Fluorescent chemotactic peptides as tools to identify the f-Met-Leu-Phe receptor on human granulocytes. 1990 Biochem. Soc. Trans. pmid:2379691
Brant AM et al. Immunological identification of five members of the human facilitative glucose transporter family. 1992 Biochem. Soc. Trans. pmid:1426534
O'Dowd Y and Newsholme P Regulation of superoxide production in human polymorphonuclear leukocytes (PMNs). 1997 Biochem. Soc. Trans. pmid:9191411
Charalambous BM et al. Detection of proton-linked sugar transport proteins in Enterobacteriaceae. 1989 Biochem. Soc. Trans. pmid:2546838
Hales CN et al. Sugar transport in lysosomes? 1982 Biochem. Soc. Trans. pmid:7199491
Jones MN and Nickson JK The human erythrocyte monosaccharide transporter in bilayer lipid membranes. 1982 Biochem. Soc. Trans. pmid:7199492
Haslam RJ and Lynham JA Increased phosphorylation of specific blood platelet proteins in association with the release reaction. 1976 Biochem. Soc. Trans. pmid:187490
Dean RT Effects of cytochalasin B on the pinocytosis and degradation of proteins by macrophages [proceedings]. 1979 Biochem. Soc. Trans. pmid:570939
Gallo SA et al. HIV-1 gp41 six-helix bundle formation occurs rapidly after the engagement of gp120 by CXCR4 in the HIV-1 Env-mediated fusion process. 2001 Biochemistry pmid:11591141
Tsukamoto T et al. Adenosine cyclic 3',5'-monophosphate uptake and regulation of membrane protein kinase in intact human erythrocytes. 1980 Biochemistry pmid:6243958
Schürmann A et al. Role of conserved arginine and glutamate residues on the cytosolic surface of glucose transporters for transporter function. 1997 Biochemistry pmid:9335548
King AP et al. Cytochalasin B interferes with conformational changes of the human erythrocyte glucose transporter induced by internal and external sugar binding. 1991 Biochemistry pmid:1747373
Hah JS et al. Effects of physical states of phospholipids on the incorporation and cytochalasin B binding activity of human erythrocyte membrane proteins in reconstituted vesicles. 1983 Biochemistry pmid:6626531
Cloherty EK et al. Regulation of GLUT1-mediated sugar transport by an antiport/uniport switch mechanism. 1996 Biochemistry pmid:8855962
Tai PK and Carter-Su C Monoclonal antibody to the human glucose transporter that differentiates between the glucose and nucleoside transporters. 1988 Biochemistry pmid:3191107
Reyes AM et al. Nicotinamide is not a substrate of the facilitative hexose transporter GLUT1. 2002 Biochemistry pmid:12069599
Blodgett DM and Carruthers A Quench-flow analysis reveals multiple phases of GluT1-mediated sugar transport. 2005 Biochemistry pmid:15709778
Carter-Su C et al. Reconstituted D-glucose transport from the adipocyte plasma membrane. Chromatographic resolution of transport activity from membrane glycoproteins using immobilized concanavalin A. 1980 Biochemistry pmid:7387979
Freer RJ et al. Further studies on the structural requirements for synthetic peptide chemoattractants. 1980 Biochemistry pmid:7387981
Lienhard GE et al. Monosaccharide transport system of the human erythrocyte. Identification of the cytochalasin B binding component. 1977 Biochemistry pmid:911802
Sultzman LA and Carruthers A Stop-flow analysis of cooperative interactions between GLUT1 sugar import and export sites. 1999 Biochemistry pmid:10350483
Katzen HM et al. Evidence that the insulin-like activities of concanavalin A and insulin are mediated by a common insulin receptor linked effector system. 1981 Biochemistry pmid:7028110
Yang Q and Lundahl P Immobilized proteoliposome affinity chromatography for quantitative analysis of specific interactions between solutes and membrane proteins. Interaction of cytochalasin B and D-glucose with the glucose transporter Glut1. 1995 Biochemistry pmid:7779771
Scarlata S et al. Effect of lipid packing on the conformational states of purified GLUT-1 hexose transporter. 1995 Biochemistry pmid:7779817
Gorga FR and Lienhard GE Changes in the intrinsic fluorescence of the human erythrocyte monosaccharide transporter upon ligand binding. 1982 Biochemistry pmid:7200802