CYTOCHALASIN B is a lipid of Polyketides (PK) class. Cytochalasin b is associated with abnormalities such as Renal tubular disorder and Chagas Disease. The involved functions are known as Membrane Protein Traffic, inhibitors, Metabolic Inhibition, Biochemical Pathway and Increased Sensitivy. Cytochalasin b often locates in Cytoplasmic matrix, Plasma membrane, Microtubules, Extracellular and Protoplasm. The associated genes with CYTOCHALASIN B are SLC2A2 gene, PFDN5 gene, SLC2A1 gene, OMG gene and SPEN gene. The related lipids are Steroids, Lipopolysaccharides and Liposomes. The related experimental models are Xenograft Model.
To understand associated biological information of CYTOCHALASIN B, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
CYTOCHALASIN B is suspected in Renal tubular disorder, Chagas Disease and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with CYTOCHALASIN B
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Xenograft Model are used in the study 'Endofacial competitive inhibition of the glucose transporter 1 activity by gossypol.' (Pérez A et al., 2009).
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Authors | Title | Published | Journal | PubMed Link |
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Tsukamoto T et al. | Adenosine cyclic 3',5'-monophosphate uptake and regulation of membrane protein kinase in intact human erythrocytes. | 1980 | Biochemistry | pmid:6243958 |
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Hebert DN and Carruthers A | Cholate-solubilized erythrocyte glucose transporters exist as a mixture of homodimers and homotetramers. | 1991 | Biochemistry | pmid:2029513 |
Hah JS et al. | Effects of physical states of phospholipids on the incorporation and cytochalasin B binding activity of human erythrocyte membrane proteins in reconstituted vesicles. | 1983 | Biochemistry | pmid:6626531 |
Gorga FR and Lienhard GE | Equilibria and kinetics of ligand binding to the human erythrocyte glucose transporter. Evidence for an alternating conformation model for transport. | 1981 | Biochemistry | pmid:7295669 |
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Axelrod JD and Pilch PF | Unique cytochalasin B binding characteristics of the hepatic glucose carrier. | 1983 | Biochemistry | pmid:6683102 |
Shanahan MF | Characterization of cytochalasin B photoincorporation into human erythrocyte D-glucose transporter and F-actin. | 1983 | Biochemistry | pmid:6683567 |
Carruthers A and Helgerson AL | Inhibitions of sugar transport produced by ligands binding at opposite sides of the membrane. Evidence for simultaneous occupation of the carrier by maltose and cytochalasin B. | 1991 | Biochemistry | pmid:2018762 |
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Sultzman LA and Carruthers A | Stop-flow analysis of cooperative interactions between GLUT1 sugar import and export sites. | 1999 | Biochemistry | pmid:10350483 |
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Gorga FR and Lienhard GE | Changes in the intrinsic fluorescence of the human erythrocyte monosaccharide transporter upon ligand binding. | 1982 | Biochemistry | pmid:7200802 |
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Johnson G et al. | The effects of cytoskeletal inhibitors on intestinal iron absorption in the rat. | 1985 | Biochim. Biophys. Acta | pmid:4063390 |
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Jhun BH et al. | Glucose and nucleoside transporters of human erythrocytes: effects of detergents on immunoadsorption of a membrane protein to its monoclonal antibody. | 1991 | Biochim. Biophys. Acta | pmid:1705438 |
Smolen JE et al. | The kinetics of lysosomal degranulation of human neutrophils as measured by 9-aminoacridine quenching. | 1983 | Biochim. Biophys. Acta | pmid:6830869 |
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Holman GD and Rees WD | Photolabelling of the hexose transporter at external and internal sites: fragmentation patterns and evidence for a conformational change. | 1987 | Biochim. Biophys. Acta | pmid:3545294 |
George TP et al. | Inhibition of phosphatidylcholine and phosphatidylethanolamine biosynthesis by cytochalasin B in cultured glioma cells: potential regulation of biosynthesis by Ca(2+)-dependent mechanisms. | 1991 | Biochim. Biophys. Acta | pmid:1854804 |
Löw I and Dancker P | Effect of cytochalasin B on formation and properties of muscle F-actin. | 1976 | Biochim. Biophys. Acta | pmid:132190 |
Audhya TK and Gibson KD | Effects of medium composition and metabolic inhibitors on glycosaminoglycan synthesis in chick embryo cartilage and its stimulation by serum and triiodothyronine. | 1976 | Biochim. Biophys. Acta | pmid:133721 |
Bales BL et al. | On cell membrane lipid fluidity and plant lectin agglutinability. A spin label study of mouse ascites tumor cells. | 1977 | Biochim. Biophys. Acta | pmid:16250350 |
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Franklin CC et al. | Insulin regulation of glucose metabolism in HT29 colonic adenocarcinoma cells: activation of glycolysis without augmentation of glucose transport. | 1988 | Biochim. Biophys. Acta | pmid:3052595 |
Smolen JE et al. | The roles of extracellular and intracellular calcium in lysosomal enzyme release and superoxide anion generation by human neutrophils. | 1981 | Biochim. Biophys. Acta | pmid:6271257 |
Licata AA et al. | Effects of prostaglandin E1 on the metabolism in rat parathyroid gland in vitro. | 1979 | Biochim. Biophys. Acta | pmid:760818 |
Wendel H and Dancker P | Kinetics of actin depolymerization: influence of ions, temperature, age of F-actin, cytochalasin B and phalloidin. | 1986 | Biochim. Biophys. Acta | pmid:3756187 |
Duncan R and Lloyd JB | Pinocytosis in the rat visceral yolk sac. Effects of temperature, metabolic inhibitors and some other modifiers. | 1978 | Biochim. Biophys. Acta | pmid:103581 |