CYTOCHALASIN B

CYTOCHALASIN B is a lipid of Polyketides (PK) class. Cytochalasin b is associated with abnormalities such as Renal tubular disorder and Chagas Disease. The involved functions are known as Membrane Protein Traffic, inhibitors, Metabolic Inhibition, Biochemical Pathway and Increased Sensitivy. Cytochalasin b often locates in Cytoplasmic matrix, Plasma membrane, Microtubules, Extracellular and Protoplasm. The associated genes with CYTOCHALASIN B are SLC2A2 gene, PFDN5 gene, SLC2A1 gene, OMG gene and SPEN gene. The related lipids are Steroids, Lipopolysaccharides and Liposomes. The related experimental models are Xenograft Model.

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Introduction

To understand associated biological information of CYTOCHALASIN B, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with CYTOCHALASIN B?

CYTOCHALASIN B is suspected in Renal tubular disorder, Chagas Disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with CYTOCHALASIN B

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Tuberculosis D014376 20 associated lipids
Uremia D014511 33 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Adenocarcinoma D000230 166 associated lipids
Dermatitis, Contact D003877 59 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Lung Neoplasms D008175 171 associated lipids
Wounds and Injuries D014947 20 associated lipids
Adenoma, Islet Cell D007516 7 associated lipids
Insulinoma D007340 28 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Inflammation D007249 119 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetic Nephropathies D003928 39 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Body Weight D001835 333 associated lipids
Foreign-Body Reaction D005549 10 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with CYTOCHALASIN B

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with CYTOCHALASIN B?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with CYTOCHALASIN B?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with CYTOCHALASIN B?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with CYTOCHALASIN B?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with CYTOCHALASIN B?

Xenograft Model

Xenograft Model are used in the study 'Endofacial competitive inhibition of the glucose transporter 1 activity by gossypol.' (Pérez A et al., 2009).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with CYTOCHALASIN B

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Authors Title Published Journal PubMed Link
von Figura K and Kresse H Inhibition of pinocytosis by cytochalasin B. Decrease in intracellular lysosomal-enzyme activities and increased storage of glycosaminoglycans. 1974 Eur. J. Biochem. pmid:4280968
Hansson HA and Hydén H A membrane-associated network of protein filaments in nerve cells. 1974 Neurobiology pmid:4141755
Dourmashkin RR and Tyrrell DA Electron microscopic observations on the entry of influenza virus into susceptible cells. 1974 J. Gen. Virol. pmid:4367305
Copeland M The cellular response to cytochalasin B: a critical overview. 1974 Cytologia (Tokyo) pmid:4448103
Borel JF [Biological phenomena of chemotaxis]. 1974 Mar-Apr Nouv Rev Fr Hematol pmid:4277138
Hatzfeld J and Buttin G Temperature-sensitive cell cycle mutants: a chinese hamster cell line with a reversible block in cytokinesis. 1975 Cell pmid:1170022
Goldman RD et al. Properties of enucleated cells. III. Changes in cytoplasmic architecture of enucleated BHK21 cells following trypsinization and replating. 1975 Exp. Cell Res. pmid:1170079
Ichikawa Y et al. Induction of differentiated functions which are reversibly suppressed by cytochalasin B. 1975 Exp. Cell Res. pmid:123508
Kramer JJ and Granger GA Relationship of lymphotoxin secretion and DNA synthesis in the human mixed lymphocytes reaction in vitro. 1975 Cell. Immunol. pmid:123828
Spooner BS and Conrad GW The role of extracellular materials in cell movement. I. Inhibition of mucopolysaccharide synthesis does not stop ruffling membrane activity or cell movement. 1975 J. Cell Biol. pmid:123925
Malaisse WJ et al. Role of microtubules in the phasic pattern of insulin release. 1975 Ann. N. Y. Acad. Sci. pmid:1096725
Malawista SE Microtubules and the movement of melanin granules in frog dermal melanocytes. 1975 Ann. N. Y. Acad. Sci. pmid:1096728
Alexander J Effect of the antiphagocytic agent cytochalasin B on macrophage invasion by Leishmania mexicana promastigotes and Trypanosoma cruzi epimastigotes. 1975 J. Protozool. pmid:1097661
Chertow BS et al. Subcellular mechanisms of parathyroid hormone secretion: ultrastructural changes in response to calcium, vitamin A, vinblastine, and cytochalasin B. 1975 Lab. Invest. pmid:1113510
Partridge T et al. Cytochalasin B inhibits stabilisation of adhesions in fast-aggregating cell systems. 1975 Nature pmid:1113855
Redman CM et al. Colchicine inhibition of plasma protein release from rat hepatocytes. 1975 J. Cell Biol. pmid:1141379
Menna JH et al. Characterization of an in vitro persistent-state measles virus infection: establishment and virological characterization of the BGM/MV cell line. 1975 Infect. Immun. pmid:803920
Fristom D and Fristom JW The mechanism of evagination of imaginal discs of Drosophila melanogaster. 1. General considerations. 1975 Dev. Biol. pmid:807489
Beloussov LV et al. Mechanical stresses and morphological patterns in amphibian embryos. 1975 J Embryol Exp Morphol pmid:1082486
Edwards JG et al. Trypsinized BHK21 cells aggregate in the presence of metabolic inhibitors and in the absence of divalent cations. 1975 J. Cell. Sci. pmid:173727